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Brigitta Laksmi Paramita
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Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati
Published by Universitas Atma Jaya Yogyakarta
ISSN : 25273221     EISSN : 2527323X     DOI : doi.org/10.24002/biota
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology
Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati merupakan jurnal ilmiah yang memuat hasil-hasil penelitian, kajian-kajian pustaka dan berita-berita terbaru tentang ilmu dan teknologi kehayatian (biologi, bioteknologi dan bidang ilmu yang terkait). Biota terbit pertama kali bulan Juli 1995 dengan ISSN 0853-8670. Biota terbit tiga nomor dalam satu tahun (Februari, Juni, dan Oktober).
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 1,193 Documents
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Dualisme Pemanfaatan Gulma Genjer (Limnocharis flava): Peluang Sebagai Agen Fitoremediasi dan Pangan Nutraseutika Ramagita, Marsahanda Astri; Ie, Johanes Juan Yutama Putra; Kasmiyati, Sri; Kristiani, Elizabeth Betty Elok
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.10270

Abstract

Tanaman Genjer (Limnocharis flava) adalah salah satu jenis gulma yang memiliki fungsi ganda sebagai bahan pangan nutraseutikan dan agen fitoremediasi. Pemanfaatan Genjer sebagai bahan pangan didasarkan pada kandungan metabolit sekunder yang terdapat didalamnya, seperti flavonoid, fenol, serta antioksidan yang berpotensi untuk dikembangkan sebagai bahan pangan fungsional serta obat tradisional. Selain itu, kemampuan tanaman Genjer sebagai agen fitoremediasi dalam menyerap senyawa pencemar seeperti logam berat, menjadikannya efektif dalam pengelolaan limbah cair. Tujuan review artikel ini dibuat untuk mengeksplorasi keunggulan dan tantangan dalam pengaplikasiannya. Metode penelitian ini yaitu literature review dengan menentukan topik yang dikaji, mengumpulkan artikel – artike, evaluasi, dan interpretasi hasil. Artikel yang digunakan merupakan artikel penelitian dari tahun 2015-2024 dan berasal dari google scholar. Hasil review menunjukkan bahwa tanaman Genjer tidak hanya berperan dalam kesehatan manusia melalui kandungan nutrisinya. Tapi juga mendukung keberlanjutan lingkungan dengan kemampuan sebagai agen fitoremediasi. Dengan pemahaman yang lebih lanjut, tanaman Genjer dapat dioptimalkan sebagai solusi yang inovatif dalam bidang pangan serta lingkungan.
Pharmacological Benefits of Porang (Amorphophallus muelleri Blume): A Review Isnaini, Hanik; Yuhana, Titan Memory; Sholehah, Washeilatus; Jannah, Akyunul
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.10308

Abstract

Porang (Amorphophallus muelleri Blume) is a tuber plant from the Araceae family that grows wild in Indonesian forests. Porang tubers have a high content of the active compound glucomannan, a low-calorie hydrocolloid dietary fiber with various health benefits. However, its potential in the pharmaceutical field has not been fully explored scientifically, so this scientific review aims to explore the potential of glucomannan and other bioactive compounds in porang in the pharmaceutical field based on literature studies, as well as the challenges of developing it as a leading commodity in Indonesia. In addition to glucomannan, porang also contains secondary metabolites such as alkaloid, flavonoids, saponins, tannins, and steroids. Research studies show that porang can be used in the treatment of various diseases, such as diabetes (especially type-2 diabetes mellitus), obesity, hypertension, and has the potential as anti-cholesterol, anti-tumor, anti-inflammatory, prebiotic agent, anti-bacterial, and wound healing. The majority of applications that are still in preclinical in vivo trials on experimental animals and the presence of calcium oxalate as an irritant compound are the challenges of developing Porang as herbal medicine. Therefore, the use of porang as herbal medicine still requires further research regarding safe processing and clinically appropriate dosage. Keywords: cacao fruit-rot, Phytophthora palmivora, biological control, decomposer.
Allium spp. as a Source of Bioactive Antibacterials: A Review of Compounds, Mechanisms, and Effectiveness Hasibuan, Febry Rahmadhani; Pujiyanti, Aloysia Sri; Ilmi, Annisa Nurul; Hariani, Nova
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.10858

Abstract

Allium spp. has long been recognized for its diverse therapeutic benefits, particularly as a natural source of antibacterial agents. Various bioactive compounds found in Allium spp., such as allicin, diallyl disulfide, ajoene, and quercetin, have demonstrated significant antimicrobial activity against both gram-positive and gram-negative bacterial pathogens. Research on the mechanisms of antibacterial action of these compounds reveals that they work by disrupting bacterial cell membranes, inhibiting protein synthesis, and interfering with bacterial metabolism. This literature review aims to examine existing studies on the antibacterial potential of Allium spp., reviewing the bioactive compounds involved, their mechanisms of action, and their effectiveness in inhibiting bacterial growth, including antibiotic-resistant pathogens such as methicillin- resistant Staphylococcus aureus (MRSA) and Escherichia coli. The findings of this review indicate that while their effectiveness may vary depending on the specific compound and form of application, Allium spp. shows considerable promise as a natural alternative for combating bacterial infections and addressing the growing issue of antibiotic resistance. This article provides deeper insights into the relevance and potential of Allium spp. in the development of antimicrobial therapies based on natural sources through a literature-based approach.
Enhancing Red-Chili (Capsicum annuum L.) Growth Using Black Soldier Fly (Hermetia illucens) Probiotics as Carrier Hadid, Mulyana; Sanjaya, Yayan; Kusnadi
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.11214

Abstract

Red chili (Capsicum annuum L.) is a crucial horticultural commodity in Indonesia, necessitating expansion to meet the growing food demands. The formulation of carriers with probiotics is a promising solution for improving red chili growth. This study examines how the combination of carriers containing bacteria and Trichoderma from the intestines of Hermetia illucens larvae affects the growth of red chili cultivar Lembang-1. The research method used a Randomized Block Design (RBD) with six treatments. The treatment consisted of a group with the addition of a kaolin carrier with bacteria and Trichoderma (BTrK), a talc carrier with bacteria and Trichoderma (BTrT), a zeolite carrier with bacteria and Trichoderma (BTrZ), and a control group without a carrier (KtC), a positive control (K(+)), and a negative control (K(-). The Least Significant Difference (LSD) test showed that the addition of carriers affected increasing plant height and the number of branches compared to the negative control. Specifically, BTrK demonstrated the highest number of leaves and branches. The result concluded that adding carriers with probiotics from the intestine isolate of BSF larvae contributes to the improved growth of red chili. The implementation of carrier addition with probiotics is considered to be a sustainable strategy in agriculture.
Isolation and Screening of Cellulolytic Soil Bacteria from Dramaga Forest in Bogor Weridyaningrum, Ratu; Imaningsih, Witiyasti; Fasha, Gusti Nur Aida
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.11262

Abstract

Cellulolytic bacteria can produce cellulase enzymes, which allow them to degrade cellulose into simpler chemicals while using it as a growth substrate. These bacteria have drawn a lot of interest due to their unique properties and potential uses, such as in agriculture and the food industry. Soil is one of the habitats of cellulolytic bacteria. This study aims to determine the potential and screening of cellulolytic bacterial isolates. Cellulolytic bacteria were isolated from soil samples and cultured using selective Carboxyl Methyl Cellulose (CMC) media. Five purified isolates were collected, and their cellulase enzyme activity was qualitatively assessed using the Congo red test. Isolated bacteria code Area Jalan Setapak (AJS1) produced a higher clear zone index and will be used for further testing. Quantitative analysis of isolate AJS1 revealed its highest enzyme activity after ten minutes of incubation, with 0.0049 U/mL unit activity and 0.018 U/mg specific activity. Based on morphological and biochemical characteristics, isolated AJS1 was identified as Corynebacterium spp.
Sago Starch-Lipid Complex Formation under Varying Fatty Acid Concentrations for Emulsion Stability Improvement Tethool, Eduard Fransisco; Pranoto, Yudi; Raharjo, Sri; Supriyadi, Supriyadi
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 2 (2025): June 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i2.11610

Abstract

The amount of fatty acids added is critical in creating starch-lipid complexes, which can affect their formation and properties. To use the complex to stabilize oil-in-water emulsion systems, this study intends to assess the effects of fatty acid concentrations on the effectiveness of starch-lipid complex formation and the properties of the resulting complexes. Ultrasonication was used to produce starch-lipid complexes from sago starch with different fatty acid contents (10, 12.5, 15, 17.5, and 20%) for the study. The results demonstrated that adding fatty acids up to 15% concentration significantly improved the water absorption capacity (WAC). In contrast, increasing the complexing index (CI), relative crystallinity (RC), oil absorption capacity (OAC), and contact angle of sago starch-lipid complexes. When the concentration of fatty acids was raised over 15%, the properties of the starch-lipid complex did not change considerably. A concentration of 15% with CI 67.07%, RC 37.94%, WAC 1.352 mL/g, OAC 1.370 mL/g, contact angle 70.82 °, emulsion capacity 36.72%, and emulsion stability 35.80% was shown to be the optimal amount of fatty acids for the production of sago starch-lipid complex. Emulsion stability and capacity can be maintained using a sago starch-lipid complex with an ideal fatty acid concentration of 15%.
Formulated Pellet Feed from Cabbage Waste and Fish Meal for Local Catfish (Clarias batrachus) Yuansah, Afrika; Listiana, Ika; Supriyadi
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 3 (2025): October 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i3.11601

Abstract

Cabbage waste is household and market industry waste that contains significant nutrients, such as protein, fat, fiber, vitamins, and minerals. This waste has the potential to be utilized as animal feed, for example, for local catfish (Clarias batrachus). This study aims to utilize cabbage waste as an alternative feed. The research was conducted from April to June 2024 using a quantitative experimental method and proximate analysis on the feed, with four treatments, three replications, and a positive control. The results showed that treatment 3, with a feed dosage of 12%, was the most effective in influencing all observed parameters. This treatment resulted in a length growth of 14.22 cm, weight growth of 20.59 g, and a feed conversion ratio (FCR) of 1.73, which was better than the other treatments. The proximate analysis results indicated that the feed in treatment 3 contained 32.14% protein, 5.24% fat, and 9.30% carbohydrates.
In Silico Study of Hops Plant Compounds (Humulus lupulus L.) as Phytoestrogens for Insulin Resistance Siagian, Johanna Berliana; Hermansyah, Inas Fathinah; Pendy, Violent Irene; Wibowo, Mutia Amara Putri; Haq, Dhiya'Ul; Pramudita, Fransisca Widi; Aulifa, Diah Lia
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 3 (2025): October 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i3.12143

Abstract

Postmenopausal women often experience insulin resistance, a condition linked to declining estrogen levels. Structurally similar to endogenous estrogen, phytoestrogens derived from Humulus lupulus L. (hops) hold potential as natural agents in hormone replacement strategies. This research utilized a comprehensive in silico methodology to assess 20 bioactive hop-derived compounds for their ability to act as agonists of estrogen receptor alpha (ERα). The evaluation involved Lipinski’s Rule of Five, ADME-Tox profiling, pharmacophore-based screening, and molecular docking analyses. Seven compounds satisfied the pharmacophore model criteria. Among them, Isoxanthohumol and 8-prenylnaringenin displayed the most favorable binding affinities, while Desmethylxanthohumol and Naringenin showed interaction patterns closely aligned with those of the native ligand. Although the majority demonstrated favorable pharmacokinetic properties, a few compounds presentedpotential mutagenic or carcinogenic effects. Considering binding performance, interaction resemblance, and predicted safety, these four compounds emerge as strong phytoestrogen candidates for ERα modulation in insulin resistance. Experimental validation through biological studies is necessary to substantiate these computational findings.
Studi Pendahuluan Tipe Sarang Alami dan Semi Alami Penyu di Pantai Pelangi Yudha, Donan Satria; Putranto, Dimas Anggoro; Putri, Rahmi Ramadhani
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 3 (2025): October 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i3.8136

Abstract

Penelitian jenis penyu, sarang alami dan semi-alaminya di Pantai Selatan Yogyakarta telah beberapa kali dilakukan. Hasilnya pantai di Bantul termasuk Pantai Pelangi memiliki lokasi pendaratan penyu untuk bertelur yang baik. Penelitian jenis dan sarang penyu di Pantai Pelangi perlu diperbaharui. Penelitian ini bertujuan untuk mengkaji awal jenis penyu yang bersarang di pantai Pelangi selama Juni hingga Agustus tahun 2023 dan mengetahui pengaruh karakter fisik sarang alami dan semi-alami terhadap keberhasilan penetasan telur. Penelitian dilakukan pada Juni hingga Agustus 2023 di Pantai Pelangi, Kabupaten Bantul, Daerah Istimewa Yogyakarta. Penelitian dilakukan dengan metode survei. Data yang didapatkan: Penyu yang mendarat dan bertelur di Pantai Pelangi adalah penyu lekang (Lepidochelys olivacea). Kegagalan penetasan telur penyu di Pantai Pelangi disebabkan oleh beberapa hal, yaitu: lebar sarang semi-alami yang lebih sempit dari sarang alami; kedalaman sarang semi-alami terlalu dalam dan tegak lurus dibandingkan sarang alami; dan suhu pasir sarang semi-alami cukup panas. Saran: sarang semi-alami tidak perlu menggunakan ember, agar lebar dan kedalaman sarang dapat disesuaikan, kedalaman sarang dibuat agak miring guna memudahkan tukik merangkak keluar; perlu naungan di area sarang semi-alami guna mengurangi suhu panas pasir sarang semi-alami.
Potensi Propolis Homotrigona apicalis Sebagai Inhibitor NLRP3 Pada Aterosklerosis: Studi in silico Lestari, Ika Widya; Siregar, Khalish Arsy Al Khairy; Kustiawan, Paula Mariana
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 10, No 3 (2025): October 2025
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v10i3.10862

Abstract

Peradangan adalah respons perlindungan sistem imun terhadap  kekebalan rangsangan berbahaya. Aterosklerosis, penyakit pembuluh darah progresif yang ditandai penumpukan plak lemak dinding arteri, disebabkan oleh peradangan. NLRP3 berperan dalam berbagai penyakit inflamasi, termasuk aterosklerosis. Alternatif berbasis bahan alami seperti propolis Homotrigona apicalis dapat mengurangi peradangan dan mencegah perkembangan penyakit. Sebaliknya, obat antiinflamasi seperti NSAID dan steroid sering memiliki efek samping. Untuk pemahaman dari interaksi ini, digunakan pendekatan molekuler docking. Pendekatan ini memungkinkan penggunaan senyawa propolis H.apicalis sebagai antiinflamasi yang aman dan efektif. Dengan menggunakan metode molekuler docking, penelitian ini mengkaji potensi senyawa propolis H. apicalis sebagai penghambat jalur peradangan NLRP3 pada aterosklerosis. Senyawa dalam propolis, seperti Alpha-Amyrin dan Beta-Amyrin, menunjukkan aktivitas anti-inflamasi melalui interaksi hidrofobik dengan residu kunci pada protein NLRP3. Nilai afinitas ikatan tinggi Alpha-Amyrin (-10,7) kcal/mol dan Beta-Amyrin (-10,6kcal/mol), menunjukkan potensi penghambatan inflamasi yang efektif. Maka dapat disimpulkan bahwa Senyawa Alpha-Amyrin dan Beta-Amyrin dari propolis H. apicalis memiliki potensi sebagai penghambatan jalur inflamasi NLRP3 dalam aterosklerosis. Hal ini mengindikasikan Alpha-Amyrin sebagai kandidat yang sangat kuat dengan Beta-Amyrin sebagai senyawa pendukung dengan potensi serupa.

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