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Jurnal Kesehatan
Published by Universitas Islam Negeri Alauddin Makassar
ISSN : 20862555     EISSN : 26227363     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Kesehatan is an academic journal that publishes medical and health scientific articles. We regularly publish the issues in June and December. The journal accepts research-based papers, literature/health research regarding of pharmacy, nursing public science and midwifery. This journal published by Medical and Health Science Faculty, Universitas Islam Negeri Alauddin Makassar.
Arjuna Subject : -
Articles 206 Documents
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ACE2 EXPRESSION OF HYPERTENSIVE RAT LUNGS GIVEN ACE-I, CCB, AND SWITCHING ACEI TO CCB Abustani, Muthiah; Arsyad, Aryadi; Idris, Irfan; Djabir, Yulia Yusrini; Djaharuddin, Irawaty; Kasim, Hasim; Ismail, Amirah Febrianti
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.38444

Abstract

Latar belakang : Hipertensi merupakan komorbid terbanyak pada COVID-19 dan ACE2 sebagai reseptor yang akan berikatan dengan virus SARS-COV-2, juga berperan dalam regulasi tekanan darah. Penggunaan obat antihipertensi seperti ACE-I atau CCB dapat mempengaruhi ekspresi ACE2. Penggunaan ACE-I selama pandemi menuai pro dan kontra yang memunculkan saran penggantian golongan obat antihipertensi seperti CCB. Tujuan : Mengetahui ekspresi ACE2 jaringan paru tikus setelah induksi hipertensi dan dilanjutkan dengan pemberian ACE-I (kaptopril) atau CCB (amlodipine), dan switching ACE-I menjadi CCB. Metode : Post control group design menggunakan 30 sampel tikus Sprague dawley yang dibagi menjadi 5 kelompok yaitu non-hipertensi, hipertensi, hipertensi + ACE-I, hipertensi + CCB, dan hipertensi + ACE-I switching CCB. Induksi hipertensi menggunakan L-NAME selama 6 minggu dan pengukuran tekanan darah menggunakan metode non-invasif. Pemberian obat antihipertensi diberikan selama 1 minggu. Ekspresi ACE2 diukur menggunakan ELISA kit Elabscience®. Hasil : Ekspresi ACE2 pada kelompok non hipertensi vs hipertensi tidak ditemukan perbedaan bermakna. Ekspresi ACE2 pada kelompok hipertensi dengan pengobatan ACE-I vs CCB ditemukan lebih tinggi pada kelompok CCB (p = 0.042). Ekspresi ACE2 pada kelompok hipertensi dengan pengobatan lebih tinggi dibanding kelompok hipertensi tanpa pengobatan (p = 0.001). Diskusi : Ekspresi ACE2 lebih tinggi pada kelompok dengan pengobatan ACE-I dengan cara menghambat efek Angiotensin II, sehingga kadar ACE2 meningkat sebagai mekanisme kompensasi. Sedangkan CCB akan meningkatkan kadar Angiotensin I dan menurunkan rasio Angiotensin (1-7)/ Angiotensin I dan menurunkan rasio ACE2/ACE Kesimpulan : Ekspresi ACE2 meningkat pada jaringan paru hipertensi dengan pengobatan ACE-I, CCB, dan switching ACE-I menjadi CCB.
PELUANG PEMANFAATAN TERAPI LASER AKUPUNKTUR SEBAGAI ADJUVAN PEMBENTUKAN ANTIBODI TERHADAP PASIEN PASKA VAKSINASI VAKSIN SINOVAC Flora Eka Sari
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.38837

Abstract

Vaccination is often really needed by the community, especially in pandemic conditions, namely when the formation of antibodies is needed quickly, so that the vaccine's permit is considered an emergency decision. The formation of vaccine antibodies also depends on adjuvants, namely substances added to strengthen the formation of antibodies. The most commonly used adjuvants are aluminum salts, but they are not always optimal. The adjuvant view of vaccines can shift to a holistic meaning that is bioenergetic and homeostatic. For this purpose, the vaccine can be optimized with a 650nm bioenergetic laser administered at acupuncture points, becoming a vaccine adjuvant. The purpose of this study was to provide an overview of the benefits of laser acupuncture as a vaccine adjuvant, namely to increase antibodies and administer vaccines. This research wants to prove the increase in Sinovac vaccine RBD antibody titer, which at the beginning. This research method is a two-group, two-posttest only design (observational) with a control group and purposive sampling in collaboration with Lakespra and laboratory approval, starting in early February 2022 and ending in March 2022. Subjects who met the inclusion and exclusion criteria were given vaccine administration according to their group, and then blood specimens were taken for RBD antibody testing. The data was evaluated to see the increase in antibodies after the first and second vaccines compared to the control group of the prediction was in doubt about the formation of antibodies.
STATUS KEBERSIHAN RONGGA MULUT DAN KEBUTUHAN PERAWATAN JARINGAN PERIODONTAL PADA LANSIA DI DAERAH PESISIR PUGER, KABUPATEN JEMBER Utha, Maria Fransisca; Fany, Manta; Wahyukundari, Melok Aris; Pudjiastuti, Peni; Prasetya, Rendra C.; Harmono, Happy; Wanodyo, Ari Tri; Sari, Desi Sandra
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.38943

Abstract

Background: Periodontal disease is a dental and oral health problem that is often experienced by the elderly. Aging affects the ability of the elderly to carry out their daily activities, including cleaning the oral cavity. Increased accumulation of calculus due to poor oral hygiene can lead to the incidence of periodontal disease which affects the quality of life of the elderly. Purpose: to examine the status of oral hygiene and the need for periodontal tissue care in the elderly in the Pesisir Puger and Payangan area, Jember Regency. Methods: Descriptive observational with a cross-sectional approach. Subjects were selected as many as 192 elderly by purposive sampling technique. Data were obtained by taking questionnaires and clinical examinations in the form of OHI-S and CPITN. Results: the majority of elderly in the Pesisir Puger area of Jember district have a poor oral hygiene status of 96.88% and , the condition of the periodontal tissue has a 4-5 mm periodontal pocket of 66.67% and the need for periodontal tissue treatment is in the form of oral hygiene instructions and SRP procedures of 96.88%. Conclusion: Majority of the elderly in Pesisir Puger and Payangan have poor oral hygiene and require periodontal tissue treatment in the form of oral hygiene instructions and scaling and root planing procedures
THE POTENTIAL OF SECANG WOOD DECOCTION AS AN ODOR CONTROL FOR DIABETIC FOOT ULCER : POTENSI AIR REBUSAN KAYU SECANG SEBAGAI PENGONTROL BAU ULKUS KAKI DIABETIK Harli, Kurnia; Irfan; Febrianti, Nur Auliyah; Azzahra, Siti Fatimah; Bauk, Ikram; Mursyid, Aco
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.39658

Abstract

Diabetic foot ulcers are a serious complication that can significantly affect the quality of life for individuals with diabetes. One common issue associated with diabetic foot ulcers is the presence of unpleasant odors. This study aims to investigate the potential of secang wood decoction as an effective odor control for diabetic foot ulcers. This research follows an experimental design with pre-test post-test control group. The study sample consists of 32 patients with diabetic foot ulcers, randomly assigned to two groups. The treatment group received wound cleansing with secang wood decoction, while the control group was washed with a 0.9% NaCl solution. The results indicated a significant reduction in odor intensity both treatment and control group. This research concludes that secang wood decoction demonstrated potential effectiveness in controlling odors associated with diabetic foot ulcers. These findings suggest that secang wood decoction holds promise as a natural and accessible method for managing odor in diabetic foot ulcers. Further research is needed to explore its long-term effects and potential side effects. Additionally, studies with larger sample sizes and diverse populations would provide more comprehensive insights into the effectiveness and safety of secang wood decoction as an odor control measure for diabetic foot ulcers.
THE APPLICATION OF LEAN HOSPITAL IN ANALYZING THE WAITING TIME OF INPATIENT PATIENTS AT THE EMERGENCY ROOM OF UNHAS HOSPITAL Wirawan, Nur Surya
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.52031

Abstract

The purpose of this study was to examine the variables that affect the length of waiting time for inpatients in the UNHAS Hospital Makassar emergency room when using the Lean Hospital strategy. This study employed a qualitative methodology that included in-depth interviews with 36 patients and emergency room staff in addition to real-time observation. Descriptive interpretation of the data was carried out, along with value stream mapping to illustrate waiting times and fishbone problem analysis According to the findings, patients at emergency rooms had to wait six hours and six minutes. During patient surveillance, non-value-adding activities predominate, with the main ones being waiting time waste, human talent, flaws, overprocessing, motion, overproducing, and transportation. The resources analysis reveals that more personnel, specifically admissions and registration officials, are required.
GAMBARAN STATUS KEBERSIHAN RONGGA MULUT DAN KESEHATAN JARINGAN PERIODONTAL PADA LANSIA DI WILAYAH PERKEBUNAN RENTENG (STUDI KASUS DI DESA MANGARAN, KECAMATAN AJUNG, KABUPATEN JEMBER) Sonya Cut Yumita Putri; Peni Pujiastuti; Depi Praharani
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.35718

Abstract

Periodontal disease is an infection in the tissues supporting the teeth. In general, periodontal disease consists of gingivitis and periodontitis. The main cause of this disease is dental plaque bacteria. This disease can affect anyone, including the elderly. Periodontal disease is caused by degenerative changes and plaque accumulation over a long period of time. The purpose of this study was to determine the description of oral hygiene status and periodontal health of elderly in Renteng Plantation area (Mangaran Village, Ajung District, Jember Regency). The research method was observational descriptive cross-sectional, with 90 people divided into two groups of 60–69 years and 70 years. The examinations included oral hygiene with OHI-S and periodontal tissue health with CPITN are presented in tables and figures. The results showed that the level of oral hygiene based on the OHI-S score was 1 person (1.1%) classified as good, 14 people (15.6%) classified as moderate, and 75 people (83.3%) classified as poor. In examining the health status of periodontal tissue based on the CPITN score, 46 people (51.1%) had score of 2, 40 people (44.4%) had score of 3, and 4 people (4.5%) had score of 4. No one had CPITN scores of 0 and 1. The conclusion is that the oral hygiene status of the elderly in the joint plantation area mostly classified as poor at 83.3%. Meanwhile, the health status of the periodontal tissue was mostly found to have supragingival or subgingival calculus at 51.1%.
HUBUNGAN HUBUNGAN AKTIVITAS FISIK DENGAN KEJADIAN DIABETES MELITUS TIPE 2 DI PUSKESMAS BANJAREJO Lutfiah, Nabilla Fitriq Lailattul; Ratnawati, Riska; Wibowo, Pipid Ari
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.39127

Abstract

Diabetes mellitus was a chronic disease that lead to metabolic disturbances, which characterized by an increase in blood glucose levels above normal. The incidence of type 2 diabetes mellitus is among the top 10 disease trends in the city of Madiun. Based on data from the Banjarejo Health Center, the number of type 2 diabetes mellitus patients in the elderly aged 60-74 years in 2022 was 58 cases. The objective to analyze the relationship between physical activity and the incidence of type 2 diabetes mellitus of Banjarejo Health Center. The research method with a case-control study design. The population includes all patients with type 2 diabetes mellitus in the working area of Banjarejo Health Center. The sample consist 78 respondents. The sampling technique used simple random sampling. The data this study obtained through questionnaires and interviews. The data analysis includes univariate analysis and bivariate analysis using the Chi-Square test. The research results revealed a relationship between physical activity and the occurrence of type 2 diabetes mellitus (P value = 0.000; OR = 14.481; 95% CI = 3.823-54.858).
KEMAMPUAN GEL EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora) DALAM MENURUNKAN TRAP PADA TIKUS MODEL PERIODONTITIS YANG DIINDUKSI KOMBINASI LPS P. gingivalis DAN WIRE NITI Rachmawati, Dessy; Setyaningsih, Sari; Herniyati; Rahmah, Tanzilal Azizir
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.39781

Abstract

Periodontitis is an inflammatory disease of the tooth supporting tissues caused by pathogenic microorganisms in dental plaque. P. gingivalis as the main etiology of periodontitis has a virulence factor in the form of lipopolysaccharide (LPS). The use of NiTi wires in initial orthodontic treatment can exacerbate periodontitis. Robusta coffee beans contain active compounds such as chlorogenic acid, caffeic acid, ferulic acid and caffeine as anti-inflammatories and antioxidants. This study aims to analyze the ability of robusta coffee bean extract gel to reduce TRAP in a rat model of periodontitis induced by the combination of LPS P. gingivalis and NiTi wire. The 28 male wistar rats were classified into 7 groups of normal (K), injected with LPS (P1), NiTi wire (P2), combination of LPS and NiTi wire (P3), injected with LPS and 500 mg/ml robusta coffee bean gel (P4), NiTi wire and 500 mg/ml robusta coffee bean gel (P5), combination of LPS and NiTi wire with 500 mg/ml robusta coffee bean gel (P6). The rats were decapitated, and then the tissue was stained with HE and IHC. The expression of TRAP was counted in the area around alveolar bone of the lower-left M1. Data were analyzed using SPSS software by going through several test, such as Saphiro-Wilk, Levene-Test, Kruskal-Wallis, and followed by Mann-Whitney. The results of TRAP expression showed a significant decreased (p<0,05) on combination of LPS and NiTi wire with robusta coffee bean extract gel. Robusta coffee bean extract gel was able to reduce TRAP expression on periodontitis model rats induced by the combination of LPS P. gingivalis and NiTi wire.
ANALISIS KESUKSESAN SISTEM INFORMASI SIBUBA DALAM PENCATATAN DAN PELAPORAN P4K KABUPATEN BONDOWOSO Vindiarta Ansori, Fara; Khoiri, Abu; Sandra, Christyana
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.39927

Abstract

The childbirth planning and complication prevention (P4K) program is one of the efforts to reduce MMR and IMR. One activities of P4K is to record and report on mothers and babies. In 2019, Bondowoso district published a maternal and infant recording and reporting application called SIBUBA. During its use, the SIBUBA application experienced errors when officers entered data but the data did not appear in the system. This study aims to analyze the factors related to the success of the SIBUBA information system in supporting the recording and reporting of the P4K program in Bondowoso district. This research is an analytic study with a cross sectional design. The research is conducted in 5 health center areas selected by cluster sampling with a total sample of 52 respondents. Data analysis is conducted with logistic regression test. The results showed that system quality (p = 1.182), information quality (p = 0.629), service quality (p = 0.551) have no effect on usage. System quality (p = 0.017), information quality (p = 0.003), service quality (p = 0.011) affect user satisfaction. The usage (p = 0.222) has no effect on net benefits. User satisfaction (p=0.001) affects net benefits.
HUBUNGAN STATUS EKONOMI DAN DUKUNGAN SUAMI DENGAN KEJADIAN DEPRESI POSTPARTUM Ratna Kusuma, Wulan; Achyar, Khamidah
Jurnal Kesehatan Vol 17 No 2 (2024): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v17i2.40798

Abstract

Background: The issues postpartum mothers face in Puskesmas II Kembaran's working area are a lack of support, particularly from their husbands, and economic conditions that may not adequately meet their needs. Objective: This study aimed to determine the correlation between economic status, husband's support, and the incidence of postpartum depression in the working area of Puskesmas II Kembaran. Method: This quantitative study employed a Cross-Sectional approach. The total sampling technique was obtained to select 52 postpartum mothers within two weeks of delivery in the working area of Puskesmas II Kembaran. Data were collected using questionnaires and analyzed bivariate through the Chi-Square test. Results: The univariate analysis results revealed that the average age of postpartum mothers was between 20 to 35 years (94.2%), with a High School education level (42.3%), and primarily primiparous mothers (53.8%). Most postpartum mothers obtained a low economic status on average (59.6%) and a high economic status on average (40.4%). About (59.6%) of postpartum mothers received their husband's support, while (40.4%) did not. The incidence of mild postpartum depression in Puskesmas II Kembaran was (51.9%), and (48.1%) of respondents did not experience postpartum depression. The bivariate analysis using the Chi-Square test indicated a correlation between economic status, husband's support, and the incidence of postpartum depression in the working area of Puskesmas II Kembaran, with a P-value of 0.000. Conclusion: There is a correlation between economic status, husband's support, and the incidence of postpartum depression in the working area of Puskesmas II Kembaran. Therefore, economic status and husband's support are crucial for postpartum mothers.

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