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Journal : Jurnal Riset Ilmiah

PERBANDINGAN FAKTOR RISIKO DAN MANIFESTASI KLINIS HPV 16 DENGAN HPV 18 PADA PENDERITA KARSINOMA SERVIKS Anavelda, Aura Putri; Putra, Andani Eka; Defrin, Defrin; Suharti, Netti; Antonius, Puja Agung; Elmatris, Elmatris
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 4 (2025): SINERGI : Jurnal Riset Ilmiah, April 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i4.1114

Abstract

Background: High-risk Human Papillomavirus (hrHPV) infection causes 99.7% of cervical carcinoma cases. Among the thirteen types of hrHPV, types 16 and 18 have a strong correlation with- cervical carcinoma. HPV 16 infection makes the immune system in the cervix hyporesponsive compared to HPV 18 infection. Objective: This study aims to compare the risk factors and clinical manifestations of HPV 16 with HPV 18 in cervical carcinoma patients. Method: This is an analytic study with a retrospective cohort approach using secondary data from the research of Dr. dr. Andani Eka Putra, M.Sc and dr. Syandrez Prima Putra which has been collected into a research master table. The sampling technique was non-probability sampling with convenience sampling on 38 respondents whose specimens were stored at the Central Laboratory of Diagnostics and Research on Infectious Diseases, Faculty of Medicine, Andalas University. Data analysis was carried out using Fisher's Exact test. Results: The results of statistical tests on the comparison of marriageable age between patients with HPV 16 and HPV 18 types showed a value of p = 0.038 (p <0.05). In this study, women who are > 45 years old, married early (<20 years), have a low level of education, work as housewives, and have a multiparity history are at high risk of cervical carcinoma. Patients with HPV 16 and 18 had risk factors and clinical manifestations were not much different (p>0.05). Conclusion: There is no significant comparison of the risk factors and clinical manifestations of HPV 16 with HPV 18 in patients with cervical carcinoma.
PREVALENSI ANEMIA PADA KEHAMILAN : SEBUAH TINJAUAN LITERATUR SISTEMATIS Azmira, Nazurah; Defrin, Defrin; Burhan, Ida Rahmah; Rustam, Erlina; Antonius, Puja Agung; Yusri, Elfira
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 9 (2025): SINERGI : Jurnal Riset Ilmiah, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i9.1374

Abstract

Background : Anemia has become a public health problem that bring many potencial danger to both maternal and neonatal side. Many studies show that there are significant correlation between maternal mortality and anemia during pregnancy.Objective: This review is done to determine the prevalence and risk factors of anemia among pregnant women Methods : This study is a systematic literature review focused on the prevalence of anemia during pregnancy from 2011-2020. Literature search on Pubmed and Proquest databases was carried out to identify studies included in inclusion criteria related to prevalence of anemia during pregnancy. In this review, 60 articles were reviewed after 4105 articles found in both databases were screened using PRISMA guidelines. A total of 49589 participants from 20 developing countries were included. Results : The results showed that the rate of anemia in pregnancy range from 7,4% to 90%, with an average of 36,2%. The most reported risk factors are low economic level/ household income (10,2%), maternal age (9,6), rural residence (7,8%), educational status of the mother (7,2%)and less consumption of iron/folic acid (7,2%). Conclusion : Based on the review, available evidence suggest that prevalence of anemia remain high especially in low and middle income countries. Maximum efforts need to be initiated to help prevent anemia during pregnancies. Public should be educated on early initiation of antenatal care to enhance surveillance, identification and treatment of anemia