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Journal : JURNAL GIZI INDONESIA

Hubungan jenis kelamin, status gizi, konsumsi susu dan olahannya dengan kadar asam urat pada lansia Novianti, Anugrah; Ulfi, Eriliyabuduni; Hartati, Lilik Sri
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 2 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.951 KB) | DOI: 10.14710/jgi.7.2.133-137

Abstract

Background: The prevalence of gout increased based on age, highest at age 70-79 years 9.3%, age 60-69 years 8%, age 50-59 years 3.7%, and age 40-49 years 3.3%. Meanwhile, based on gender, the prevalence of gout diagnosed with health workers was higher in women at 13.4% compared to men 10.3%. Overweight and obesity can trigger an increase in uric acid levels, so it is one of a risk factor for hyperuricemia. Various high protein and purine foods have long been considered a risk factor for gout. Similarly, the possibility that consumption of dairy products especially cow's milk has a role in protecting the risk of gout based on the results of metabolic studies.Objective: To determined the relationship of sex, body mass index (BMI), dairy products consumption and uric acid levels of the elderly in Cipondoh Sub-District Tangerang.Methods: This study used a cross-sectional design. Research participants were collected by using purposive sampling. Primary data consisted of respondent characteristics, dairy products consumption, BMI, and uric acid levels.Results: The results of this research have shown there was a correlation between BMI and uric acid level p = 0.007, dairy products consumption and uric acid level p = 0.0001, but there was no correlation between sex and uric acid level p = 0.204 in the elderly at Cipondoh Sub-District Tangerang.Conclusion: There was a correlation between BMI, dairy products consumption with uric acid levels of the elderly in Cipondoh Sub-District Tangerang.
Melatonin menurunkan berat badan tetapi tidak menurunkan kadar TNF-α pada tikus wistar jantan yang diberi minyak jelantah selama 28 hari Novianti, Anugrah; Dharmana, Edi; Widyastiti, Nyoman Suci
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.997 KB) | DOI: 10.14710/jgi.5.2.127-132

Abstract

Backgound: Non Alcoholic Fatty Liver Disease (NAFLD) occurs when the intake and free fatty acid synthesis occurs more frequently than its oxidation and resecretion in the blood. Melatonin is a powerful antioxidant that can boost the synthesis of endogenous antioxidants in the body, suppress the inflammatory response and inhibit the formation of steatosis.Objective: To analyze the effect of melatonin supplementation in reducing body weight andTNF-α levels in male Wistar rats were fed by waste cooking oil.Methods: True experimental studyusing post-test only control group design. This study was done on 18 male wistar rats were divided into 3 groups : the positive control group (P0) was administrated waste cooking oil, the treated group 1 (P1) was administrated waste cooking oil and 5mg/kgBW melatonin, and the treated group 2 (P2) was administrated waste cooking oil and 10mg/kgBW melatonin for 28 days.Data analysis using One Way ANOVA test and followed by Tukey test to determine the most effective dose of melatonin.Results: There was significant difference in body weightbetween P2group and K0 group (p=0,019) with the mean body weight difference was 19,167g lower than K0 group. There was no difference in TNF-α levels between the three groups (p=0,155). Conclusion: Melatonin dose of 10mg/kgBWloses body weight male Wistar rats have given by waste cooking oil for 28 days, but does not reduce TNF-α levels.