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Review Artikel: Ekstrak Sebagai Antihiperlipidemia Anjani, Siti Monica; Agustina, Ani
Sains Medisina Vol 4 No 3 (2026): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v4i3.981

Abstract

Hiperlipidemia adalah gangguan metabolisme lipid yang meningkatkan kadar kolesterol total, trigliserida, dan LDL. Meskipun terapi farmakologi seperti statin efektif, penggunaan jangka panjang sering memicu efek samping, sehingga diperlukan alternatif dari bahan alam. Review ini bertujuan mengidentifikasi senyawa kimia dan penggunaan tradisional berbagai tumbuhan yang memiliki aktivitas antihiperlipidemia. Metode yang digunakan adalah studi pustaka melalui basis data Google Scholar dan PubMed dengan kata kunci spesifik seperti “Aktivitas antihiperlipidemia” dan “Antihyperlipidemic activity”. Pencarian dilakukan menggunakan operator Boolean dan filter lanjutan untuk memperoleh referensi yang akurat dan relevan. Berdasarkan sintesis terhadap 10 artikel penelitian in vivo, ditemukan bahwa ekstrak berbagai tanaman secara signifikan mampu menurunkan kadar kolesterol total pada tikus yang diinduksi pakan tinggi lemak dibandingkan dengan kontrol negatif. Senyawa metabolit sekunder seperti flavonoid, saponin, tanin, dan triterpenoid diidentifikasi sebagai komponen utama yang berperan dalam aktivitas tersebut. Mekanisme kerjanya meliputi penghambatan penyerapan lemak dan regulasi enzim metabolisme kolesterol. Hasil ini menegaskan potensi besar tanaman herbal sebagai agen antihiperlipidemia alami yang lebih aman untuk penggunaan jangka panjang.
The Effect of Family Support and Flash Card Education on Medication Adherence Among Elderly Patients with Type 2 Diabetes Mellitus Fitriani, Anita; Budi, Setia; Agustina, Ani
Indonesian Journal of Science and Pharmacy Vol. 3 No. 3 (2026): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v3i3.166

Abstract

Suboptimal medication adherence remains a major challenge in managing type 2 diabetes mellitus among older adults, particularly in primary healthcare settings with limited long-term monitoring. Limited understanding of medication use and low family involvement are frequently associated with poor adherence behavior. This study aimed to assess changes in medication adherence following the implementation of family support and flash card–based education among elderly patients with type 2 diabetes mellitus. A pre-experimental one-group pretest–posttest design was conducted involving 88 purposively selected participants. Medication adherence was measured using a validated instrument. Data were analyzed using the Wilcoxon signed-rank test to compare pre- and post-intervention scores, Spearman correlation to examine the association between family support and adherence, and multiple linear regression to identify contributing factors. The results showed a significant increase in adherence scores after the intervention (p<0.001). Family support was moderately associated with medication adherence (r=0.462). Furthermore, the combined variables explained 33.0% of the variance in adherence (R²=0.330). These findings suggest that family-oriented visual education may serve as a feasible pharmaceutical care approach to support medication adherence among elderly patients, although further controlled studies are needed to confirm causal relationships.
Edukasi Cara Pengolahan Sediaan Herbal Untuk Hipertensi di Kampung Ketupat RT. 07 Kota Banjarmasin Pebrianti, Pebrianti; Safitri, Zahra Desy; Elisier, Michael; Nawwal, Nawwal; Syifa, Nur; Agustina, Ani; Rohama, Rohama
Prima Abdika: Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2026): Volume 6 Nomor 2 Tahun 2026 (Juni 2026)
Publisher : Program Studi Pendidikan Guru Sekolah Dasar Universitas Flores Ende

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/abdika.v6i2.6989

Abstract

The rapid advancement of science and technology in pharmaceutical preparations has not entirely shifted public preference toward modern medicine. This is evident from the fact that many community groups continue to use herbal plants as alternative therapeutic options, although their knowledge regarding appropriate use remains limited. This community engagement program aimed to improve residents' knowledge and skills in Kampung Ketupat RT. 07, Banjarmasin City, in the utilization of herbal plants as antihypertensive agents. The program consisted of three phases: the preparation phase (survey and material development), the implementation phase (education and a workshop on celery juice preparation), and the evaluation phase, which involved comparing pre-test and post-test results. Educational activities were conducted in person using leaflets as learning media. The results showed an improvement in participants’ knowledge, as indicated by an increase in the number of participants with good knowledge levels—from 4 (26.67%) before the intervention (pre-test) to 10 (66.67%) after the educational session (post-test).