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PENGARUH VARIASI BASIS TERHADAP DAYA SIMPAN SALEP YANG MENGANDUNG  EKSTRAK ETANOL DAUN BELIMBING WULUH (Averhoa bilimbi (L)) Lestari, Tri Puji; Kurniawati, Evi; Widyaningrum, Esti Ambar
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.519

Abstract

            Starfruit wuluh, scientifically known as Averrhoa blimbi L., contains secondary metabolites such as flavonoids and tannins, which function as antibacterial agents. The extract of starfruit wuluh leaves is formulated into a ointment for easy application. The selection of a suitable ointment base is crucial to achieve the formulation's effectiveness. Understanding the influence of using different bases, specifically oil-in-water emulsion base and water-soluble ointment base, on the stability of ointment containing ethanol extract of starfruit wuluh leaves is the aim of this research. Stability testing is conducted for two weeks at room temperature. Physicochemical tests include organoleptic evaluation, homogeneity, adhesiveness, pH, and spreading ability of the formulation. The results indicate that the variation in the type of base does not affect organoleptic aspects, homogeneity, and pH during storage but does impact adhesiveness and spreading ability of the ointment containing starfruit wuluh leaf extract during storage
PERBEDAAN KADAR TANIN TOTAL EKSTRAK DAUN TURI (Sesbania grandiflora L.) VARIETAS MERAH DAN PUTIH DENGAN METODE SPEKTROFOTOMETRI UV-VIS Kurniawati, Evi; Lestari, Tri Puji; Hardini, Pri Hardini
Jurnal Riset Kefarmasian Indonesia Vol. 6 No. 2 (2024): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v6i2.520

Abstract

Turi is one of the plants that has activity as an antimicrobial, antifungal, anti-inflammatory and antioxidant. The content of secondary metabolites in turi leaves are flavonoids, tannins, and alkaloids. Tannins are phenol compounds with hydroxy groups and several other groups such as carboxyl. This study aims to determine the difference in total tannin levels in turi leaf extracts of red and white varieties. The extraction process with maceration using 70% ethanol solvent. Then the extract obtained was carried out screening tests, thin layer chromatography tests, and determination of tannin levels by UV-Vis spectrophotometry. Parameters of analytical method validation were carried out by determining linearity, accuracy, precision, LOD and LOQ. The results of the validation of the linearity analysis method obtained a linear regression equation y = 0.0038x + 0.3153 r value = 0.9985. The accuracy results obtained are in the range of 97-103%, RSD value of 0.18% and the LOD value is 6,213 ppm and LOQ is 20,711 ppm. The measurement results of total tannin content in turi leaf extracts of red and white varieties at a wavelength of 750 nm are 7.876% w / w TAE and 9.195% w / w TAE, respectively. Independent sample T-test results show there is a significant difference (p < 0.05) in the total tannin content of turi leaf extracts of red and white varieties. Keywords: Turi leaves, tannin, UV-vis spectrophotometer
Anticoagulant Activity and Gel Formulation of Black Garlic (Allium sativum Linn.) Extract Agustina, Lia; Prameswari, Dinasty Isna; Yuliati, Ninis; Lestari, Tri Puji; Soehartono, David Raditya
MPI (Media Pharmaceutica Indonesiana) Vol. 8 No. 1 (2026): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v8i1.8185

Abstract

Bruising or contusion can cause pain, discomfort, and aesthetic concerns that may affect phy­sical function and overall quality of life. Therefore, topical anticoagulants are needed as a targeted therapy to improve local circulation and accelerate tissue repair and recovery. However, limitations of conven­tional anticoagulants highlight the need for safer alternatives, with black garlic emerging as a promising natural source of anticoagulant bioactive compounds. This study aimed to evaluate the in vitro anticoagu­lant activity of black garlic and determine the influence of different extract concentrations on the physi­cal characteristics of gel formulations. The experimental design utilized the Lee-White method to observe blood clotting time. Gel preparations containing black garlic at concentrations of 2.5%, 5.0%, and 20.0% were formulated and evaluated for organoleptic properties, homogeneity, pH, adhesion, spreadability, vis­cosity, and irritation. The anticoagulant activity assay revealed a concentration­dependent increase in anticoagulant activity, with the 20% formulation showing the most pronounced effect. The results showed that all three concentrations exhibited anticoagulant effects. Statistical analysis using the Kruskal–Wallis revealed significant differences (p < 0.05), indicating varying anticoagulant activity among formulations. Physical evaluation showed that increasing extract concentration significantly affected pH, organoleptic properties, and viscosity, with pH ranging from 5.50–6.19, spreadability 5.75–6.36 cm, and adhesion 5.06– 5.32 s, while all formulations remained homogeneous, non-irritating, and exhibited decreased viscosity at higher concentrations (F3 was below standard). Overall, black garlic extract demonstrated potential as an anticoagulant agent in topical formulations.
Me and My Emotions: Learning to Manage Feelings and Behave Well at School Putri, Intan Alifiah; Indahyani, Riska Nur; Madani, Ely Roy; Qur'aniyah, Millatil; Sintia, Rina; Halizah, Siti Nor; Falaasifah, Imroatul; Mardiyah, Khayatul; Woko, Putri Ainnur; Lestari, Tri Puji
Society : Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2026): Mei
Publisher : Edumedia Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55824/1qd4zv82

Abstract

Bullying is often interpreted as part of aggressive behavior. This aggressivebehavior is also caused by elementary school children's difficulty in regulating their emotions. Elementary school education is a particular focus because it is the level of education that experiences the most cases of bullying and violence. The psychoeducation program “Me and My Emotions: Learning to Manage Feelings and Behave Well at School” was conducted as a community service with the aim of increasing students' knowledge of emotional regulation skills as a means of preventing bullying behavior among 6th grade students at SDN 1 Curahmalang. The results of this effort show that psychoeducation provides significant benefits for participants. Of the 36 students who were given post-test questions, the results show that psychoeducation had a positive impact on participants. From these results, it can be concluded that psychoeducation hasan impact on good emotion management. In addition, students also showed an increase in understanding about bullying and efforts to improve emotional regulation as a preventive measure against bullying, both from the perpetrators and victims.