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Preparation and Characterization of Ethanol Extract of Spons Xestospongia sp. Indalifiany, Astrid; Sahidin, Sahidin; Wahyuni, Wahyuni; Fristiohady, Adryan; Sadarun, Baru; Andriani, Rina; Aspadiah, Vica Aspadiah; Naimah, Naimah
FARMASIS: Jurnal Sains Farmasi Vol 2 No 1 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i1.3542

Abstract

Background: Xestospongia sp. is a species of the Demospongiae class that can be used as a medicinal substance. Xestospongia sp is known to have various activities such as anticancer, antibiotic, anti-fungal, cardiotonic, and antimalarial. One of the ways to make the formulation of natural ingredients is the phytosome vesicle technique. This method can be used to increase the penetration of compounds through cell membranes, increase their absorption and increase its bioavailability in the body. Objective: The aim of this study was to obtain the optimum phytosome composition in the ethanol extract of Xestospongia sp. and phosphatidylcholine with approprite vesicle characteristics. Methods: The preparation was carried out by varying the extract and phosphatidylcholine with a thin layer hydration method at a ratio of 1:1, 1:2, 2:1, and 2:2 and and phytosome characterization was carried out in each of these formulas to obtain the optimal formula. Results: In this study, the optimum phytosome formula has met the criteria based on morphological test parameters using an optical microscope obtained by spherical morphology, stability of physical appearance observations stored at 2oC-8oC ± 1oC temperature, pH measurement using a pH meter obtained a pH value of 4.20, and particle size determination using the Particle Size Analyzer (PSA) obtained a particle size of 180.6 nm and particle distribution value (IP) of 0.133. Conclusion: Composition of the optimum phytosome formula in the ratio of extract and phosphatidylcholine 1: 1 with the LUV phytosome category (Large Unilamellar Vesicle)
Edukasi Pengenalan Obat Dan Dagusibu Obat Pada Siswa Siswi Madrashah Aliyah Indotec Muhammadiyah Kendari : Education on Drug Recognition and Drug Administration for Students of Madrashah Aliyah Indotec Muhammadiyah Kendari Indalifiany, Astrid; Zubaydah, Wa Ode Sitti; Sartina, Ari; La Ogo, Annisa Rizky; Megawati, Megawati; Putri, Nadila; Surianti, Wa Ode; Zunnurain, Zunnurain
Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Vol. 3 No. 1 (2025): NADIKAMI: Januari 2025
Publisher : POLITEKNIK BINA HUSADA KENDARI

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Abstract

Penggunaan obat yang tepat merupakan aspek penting dalam menjaga kesehatan masyarakat. Namun, kesadaran dan pengetahuan masyarakat, terutama generasi muda, mengenai pengelolaan obat yang rasional masih terbatas. Program edukasi bertema "Edukasi Pengenalan Obat dan Dagusibu (Dapatkan, Gunakan, Simpan, dan Buang) Obat" telah dilaksanakan di Madrasah Aliyah Indotec Muhammadiyah Kendari sebagai bagian dari pengabdian kepada masyarakat. Kegiatan ini bertujuan untuk meningkatkan pemahaman siswa-siswi tentang konsep DAGUSIBU. Metode yang digunakan meliputi pemberian ceramah, sesi tanya jawab, diskusi interaktif, dan pemberian plakat penghargaan kepada pihak sekolah. Hasil kegiatan menunjukkan antusiasme tinggi dari siswa-siswi dan pihak sekolah. Para siswa aktif berpartisipasi dalam diskusi dengan mengajukan pertanyaan terkait penggunaan obat, pengenalan obat kadaluarsa, serta prosedur penyimpanan dan pembuangan obat yang benar. Penyampaian materi secara interaktif dan kontekstual terbukti efektif dalam meningkatkan pemahaman siswa terhadap konsep DAGUSIBU. Pihak sekolah juga memberikan apresiasi positif dan menyatakan komitmen untuk mendukung program serupa di masa mendatang. Kegiatan ini tidak hanya berhasil meningkatkan literasi kesehatan siswa-siswi, tetapi juga mempererat hubungan antara institusi pendidikan dan masyarakat. Implementasi program seperti ini diharapkan dapat diterapkan secara luas untuk mengurangi dampak negatif dari penggunaan obat yang tidak rasional, sekaligus mendorong perilaku bijak dalam pengelolaan obat di masyarakat.
Sosialisasi Dampak Negatif Kecanduan Game Online Dan Media Sosial Bagi Kesehatan Mental Remaja Smp Negeri 13 Kendari: Socialization of the Negative Impact of Online Game Addiction and Social Media for Mental Health of Adolescents of Smp Negeri 13 Kendari Wahyuni, Wahyuni; Mahmudah, Rifa’atul; Azis, Muhammad Israwan; Malik, Fadhliyah; Indalifiany, Astrid
Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Vol. 3 No. 1 (2025): NADIKAMI: Januari 2025
Publisher : POLITEKNIK BINA HUSADA KENDARI

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Abstract

Game online dan sosial media merupakan salah satu bentuk hiburan yang sering dilakukan oleh masyarakat khususnya remaja saat ini. Namun, penggunaan media sosial dan game online yang tidak terkontrol dapat mempengaruhi kesehatan mental dan menyebabkan terjadinya depresi, stress, kecemasan, bahkan kesepian. Sosialisasi dampak negatif kecanduan game online dan media sosial di SMP Negeri 13 Kendari bertujuan untuk meningkatkan pengetahuan dan kesadaran akan bahaya yang ditimbulkan terhadap kesehatan mental. Kegiatan ini melibatkan metode presentasi, diskusi, dan penyebaran leaflet untuk memberikan informasi yang komprehensif tentang efek negatif dari penggunaan berlebihan gadget, termasuk gangguan tidur, kecemasan, stres, dan penurunan prestasi akademik. Sosialisasi diawali dengan pretest untuk menilai pemahaman awal siswa dan diakhiri dengan posttest guna mengukur efektivitas program. Hasil kegiatan menunjukkan peningkatan pemahaman siswa sebesar 75%, dari sebelumnya hanya 25% yang memahami dampak kecanduan game online dan media sosial. Edukasi ini membuktikan bahwa pendekatan melalui metode ceramah dan media visual efektif dalam memberikan kesadaran akan pentingnya menjaga kesehatan mental. Dengan demikian, program ini diharapkan mampu membantu siswa mengatur penggunaan gadget secara bijak dan mendukung keseimbangan antara aktivitas digital dan kesehatan mental mereka.
PELATIHAN PEMBUATAN BAKSO UNTUK PENGGERAK PEREKONOMIAN USAHA RUMAHAN PADA DASAWISMA KEMUNING KELURAHAN KORUMBA KOTA KENDARI Arif, Norma; Bahari, Bahari; Bahari, Doddy Ismunandar; Indalifiany, Astrid; Husnaeni, Husnaeni
EJOIN : Jurnal Pengabdian Masyarakat Vol. 2 No. 5 (2024): EJOIN : Jurnal Pengabdian Masyarakat, Mei 2024
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/ejoin.v2i5.2687

Abstract

Fish-balls Processing businesses in Korumba Subdistrict, Kendari City, are generally home industry that are conducted to fill leisure time and in form household scale. This product can be enriched with Moringa leaves and chopped carrots, which are the source of vegetable protein and fiber. The target of community service is Dasawisma Kemuning which has 10 members. The objective of these community service efforts is to enhance the knowledge and abilities of Dasawisma Kemuning members in terms of (1) the production process of fish balls in healthy way and nutritious; (2) principles of making hygienic functional fish balls (3) business implementation of processed functional fish ball products that enriched with Moringa leaves and chopped carrots on a household scale; (4) the benefits of processed fish ball products as functional food that is cheap, healthy and nutritious. Derived from the entirety of training activities, not only in discussions, but also in demonstrations of making functional fish balls. The findings indicated that participants' understanding of the training content improved significantly, rising from an average score of 27.55% before the training to 98.25% in the final evaluation. Based on field implementation from the functional fish ball business shows that a raw material requirement of 2 kg/day, 295 fish balls were obtained. Based price per item of IDR 1100,- a profit/month of IDR is obtained. 3,135.00,-. Calculations of the financial aspects of functional fish balls have been resulting in a BEP value (product units sold) of 746. If in one month you can sell 746 fish balls, all costs incurred in a month are covered.
PENGEMBANGAN APLIKASI TOLAK STUNTING DAN EDUKASI PENGGUNAANYA SEBAGAI MEDIA PENINGKAT LITERASI DIGITAL UNTUK MENCEGAH STUNTING DI KONAWE SELATAN Indalifiany, Astrid; Jabbar, Asriullah; Aspadiah, Vica; Pascayantri, Asniar; Mahmudah, Rifa’atul
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 6 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i6.598

Abstract

Stunting is a health problem that has a serious impact on the growth and development of children in Indonesia, including in South Konawe, Southeast Sulawesi, which has a high prevalence of stunting. This community service program aims to improve digital literacy in the community in preventing stunting through the Tolak Stunting application. Activities include stunting education and application socialization as a digital innovation. The approach used includes interactive lectures, leaflet distribution, and application demonstrations. This application provides information about stunting, breastfeeding and MPASI guidelines, nutrition calculators, and related government programs. The results of the program show an increase in public awareness of stunting and the importance of digital literacy in understanding the causative factors and prevention efforts. This success emphasizes the importance of collaboration between digital literacy and health education to overcome stunting in the community..
PENINGKATKAN KESADARAN SISWA-SISWI SMKN 05 KENDARI MELALUI EDUKASI INTERAKTIF MENGENAI IDENTIFIKASI DAN PEMILIHAN KOSMETIK YANG AMAN DAN LEGAL Muliadi, Rahmat; Leorita, Mesi; Tias, Ayuning; Sarry, Elita Puspita; Rosmaria, Rosmaria; Hartawaty, Siska Septy; Septrilia, Shara; Aspadiah, Vica; Malik, Fadhliyah; Indalifiany, Astrid
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 6 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i6.1338

Abstract

Educating young people about product safety is becoming increasingly important as the cosmetics industry evolves rapidly. A community outreach program was held at SMKN 05 Kendari in Southeast Sulawesi to enhance teenagers’ awareness of selecting safe and legally approved cosmetic products. The program utilized an engaging educational format, including presentations, group discussions, and interactive Q&A sessions, supported by PowerPoint slides. Key topics included identifying the differences between legal and illegal cosmetics, understanding the dangers of harmful substances in beauty products, and learning how to verify products using the BPOM KLIK platform. The outcome showed a noticeable improvement in participants' knowledge regarding the selection of safe cosmetics. This initiative is expected to encourage more informed consumer choices and help reduce the use of illegal cosmetics among teenagers
PEMAHAMAN TENTANG BAHAYA PENYALAHGUNAAN NARKOBA (NARKOTIKA, PSIKOTROPIKA DAN BAHAN ADIKTIF) SERTA BAHAYA MEROKOK PADA SISWA MA PESRI KENDARI Munasari, Dian; Indalifiany, Astrid; Sartinah, Ari; Fadhilah, Ainur; Afifah, Nur; Rizal, Nurul Zahra Alifah; Sempurno, Sumino Jati; Tonapa, Sry Artha
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 6 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i6.1392

Abstract

Narkoba adalah singkatan dari narkotika dan obat atau bahan berbahaya yaitu NAPZA yang merupakan singkatan dari (Narkotika,psikotropika, dan zat adiktif). Tujuan sosialisasi ini untuk memberikan edukasi dan informasi pengetahuan mengenai pemahaman tentang bahaya penyalahgunaan narkoba serta bahaya merokok pada siswa siswi. Metode yang digunakan adalah ceramah interaktif, dengan pemberian leaflet kepada peserta untuk memberikan informasi mengenai NAPZA dan bahaya rokok. Hasil kegiatan menunjukkan bahwa siswa siswi memahami tentang bahaya narkoba dan rokok ditandai dengan siswa siswi yang menjawab pertanyaan dengan baik dan benar. Dengan demikian, pemberian edukasi mengenai bahaya akan penyalahgunaan narkoba dan rokok untuk mengurangi serta mencegah bertambahnya korban penyalahgunaan narkoba serta rokok dikalangan pelajar.
Natural Self-Foaming Clay Soap with Etlingera elatior Fruit Extract for Skincare Aspadiah, Vica; Zubaydah, Wa Ode Sitti; Indalifiany, Astrid; Sahidin, Sahidin; Fristiohady, Adryan; Malaka, Muhammad Hajrul; Muliadi, Rahmat; Parrung, Arsyani
Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i2.5800

Abstract

Etlingera elatior (Wualae), a plant recognized for its flavonoid-derived antioxidant properties, presents a potential source for cosmeceutical applications. This study investigated the formulation and evaluation of a Self-Foaming Clay Soap (SFCS) incorporating an ethanol extract of E. elatior fruit. The SFCS base, comprising surfactant as a cleansing and foaming agent combined with bentonite clay for enhanced serviceability and oil adsorption, was formulated with varying concentrations of bentonite (0%, 5%, 10%, 15%, and 20% w/w), designated as FI to FV, respectively, alongside other necessary excipients. The resulting SFCS preparations underwent rigorous physical and chemical stability assessments following accelerated storage conditions (freeze-thaw cycles). Evaluated parameters included organoleptic properties, foam stability and height, viscosity, dispersibility, homogeneity, and pH. The evaluation revealed that Formulation II (FII), containing 5% w/w bentonite, exhibited the most favorable stability profile and met the established criteria for SFCS semisolid preparations. Specifically, FII demonstrated a foam stabilization rate of 84.61% and a foam height of 2.6 cm after freeze-thaw cycling, a viscosity of 10,000 cPs, a spreadability diameter of 4.1 cm, a homogeneous texture devoid of coarse particles, and a skin-compatible pH of 5. These findings suggest that an SFCS formulation incorporating a 5% w/w concentration of bentonite and E. elatior fruit extract holds promising potential as a stable and efficacious skincare preparation.
Efek Imunomodulator Ekstrak Etanol Spons Melophlus sarasinorum Terhadap Aktivitas Fagositosis Sel Makrofag Pada Mencit Jantan Balb/C: Immunomodulatory Effects of Ethanol Extract of Melophlus sarasinorum Sponge Against Phagocytosis Activity of Macrophage Cells on Balb/C Male Mice Wahyuni, Wahyuni; Yusuf, Muhammad Ilyas; Malik, Fadhliyah; Lubis, Adryan Fristiohady; Indalifiany, Astrid; Sahidin, I
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.925 KB) | DOI: 10.22487/j24428744.2019.v5.i2.13611

Abstract

Immunomodulator is an ingredient or drug that can modulate immune system functions and activities. This study was conducted to determine the effect of ethanol extract of Melophlus sarasinorum sponge on macrophage phagocytosis activity. Twenty four male mice balb/c were divided into six groups. The first group received 100 mg/kg of ethanol extract of Melophlus Sarasinorum sponge, the second group received 200 mg/kg of ethanol extract of Melophlus sarasinorum sponge, the third group received 300 mg/kg of ethanol extract of Melophlus Sarasinorum sponge and the fourth group received 400 mg/kg of ethanol extract of Melophlus Sarasinorum sponge. The positive control group received Phyllanthus niruri linn extract (Stimuno®) 0,13 mg/g and the negative control group received NaCMC 0,5%. The extract was orally administered from first day to seventh day. On the eighth day, each of the mice was injected Staphylococcus aureus bacteria (SA) 0.5 mL intraperitoneally. Macrophage cell activity is calculated from smears of peritoneal fluid of mice. Increased doses of ethanol extract of Melophlus sarasinorum sponge increase the amount of macrophage phagocytosis activity that are 25,25% (negative control), 61,5% (positive control), 55,75% (100 mg/kg), 60,75% (200 mg/kg), 62,25% (300 mg/kg) dan 66,25% (400 mg/kg). The results showed that the ethanol extract of Melophlus sarasinorum sponge has the potential as immunomodulator at a doses of 300 mg/kgBB and 400 mg/kg with no significantly different effectiveness with positive control in increasing macrophage cell phagocytosis activity based on the result of post-hoc statistical test of Tukey (sig.> 0,05).