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All Journal Jurnal Kesehatan Lingkungan indonesia Jurnal Sumberdaya Hayati Jurnal Surya Medika Jurnal Kedokteran Universitas Palangka Raya Journal of Experimental and Clinical Pharmacy (JECP) Barigas: Jurnal Riset Mahasiswa
Frethernety, Agnes
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Differences in Urea And Creatinine Levels in St-Elevation Myocardial Infarction (STEMI) And Non-St-Elevation Myocardial Infarction (NSTEMI) at Dr. Doris Sylvanus Hospital Mallewa, Nurul Ilmi; Patricia, Tisha; Frethernety, Agnes; Permatasari, Silvani; Shinta, Herlina Eka
Barigas: Jurnal Riset Mahasiswa Vol. 3 No. 3 (2025): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v3i3.17663

Abstract

Acute Kidney Injury (AKI) in Acute Myocardial Infarction (AMI) patients occurs due to decreased blood flow to the kidneys. Decreased blood flow caused by blockage in coronary arteries of AMI patients both in ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI) which causes reduced blood flow so the oxygen supply carried by the blood to the myocardium is reduced. Decreased oxygen supply to myocardium reduces the heart's ability to pump blood throughout the body including to kidneys. Decreased blood flow to kidneys results decreased kidney function. Laboratory examination parameters commonly used to assess kidney function are urea and creatinine. This study aims to determine the differences urea and creatinine levels in STEMI and NSTEMI patients. This research method uses analytical observation with cross-sectional approach. Data urea and creatinine levels taken from medical records using a purposive sampling technique. Samples in this study was 170 people. Data analysis using the manwhitney test and the results of comparison of urea levels in STEMI and NSTEMI patients with a p value = 0.416 and for creatinine levels with a p value = 0.756. This means that there is no significant difference between urea and creatinine levels in STEMI and NSTEMI patients.
Literature Review: The Potential Activity of Secondary Metabolite Compounds in The Rutaceae Family Plants Against Streptococcus Mutans Elvariani, Ni Wayan Dessy Risma; Frethernety, Agnes; Furtuna, Dewi Klarita
Barigas: Jurnal Riset Mahasiswa Vol. 3 No. 3 (2025): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v3i3.18883

Abstract

Dental caries is caused by Streptococcus mutans, with resistance to fluoride becoming a significant challenge, thus requiring new antibacterial alternatives. The purpose of this literature review is to examine the potential of metabolite compounds from the Rutaceae plant family against S. mutans through a systematic review. The method used includes a literature review from databases such as Google Scholar, PubMed, and Research Gate (2014–2024) following the PRISMA protocol. The analysis covers plants from the Rutaceae family, bacterial inhibition zone tests, and secondary metabolite content. A total of 15 journals (6 national, 9 international) demonstrated that the Rutaceae family plants possess strong antibacterial activity. Active compounds such as flavonoids, alkaloids, tannins, saponins, and terpenoids were found in the bark, leaves, and fruits of the plants. Extracts from the bark of Citrus aurantifolia showed the largest inhibition zone against S. mutans (28.7 mm). Flavonoids and tannins played a significant role in antibacterial activity. The conclusion derived is that the Rutaceae family has great potential as a natural antibacterial agent for the prevention of dental caries. These findings provide a foundation for developing safe and effective oral care products based on natural ingredients. Further research, particularly in the formulation of safe and effective natural-based oral care products
Co-Authors Abi Bakring Balyas Abigail, Keshia Alexandra, Francisca Diana Amiani, Winney Aprelea, Reza Nathasya Berliani, Victoria Desimaria Panjaitan Dian Mutiasari, Dian Elsa Trinovita Elvariani, Ni Wayan Dessy Risma Elvina Damayanti Faradila, Faradila Fitri, Nurul Aulia Francisca Diana Alexandra Furtuna, Dewi Klarita Halisa, Nida Hanasia Handayani, Septi Herlina Eka Shinta Jakung, Benedikta Cemara Raninai Jelita, Helena Larasaty, Anggie Lestarisa, Trilianty Malik, Handayani Mallewa, Nurul Ilmi Nugrahini, Shinta Patricia, Tisha Permatasari, Silvani Prillyanisa , Pasca Purba, As Gaby Clarita Ranti, Dalia Rian Ka Praja Rovik, Anwar Sampurna Putra, Ravenalla Abdurrahman Al Hakim Sri Yuliani, Ni Nyoman Turnip, Oktaviani Naulita Widayati, Ratna Ysrafil, Ysrafil