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All Journal Gema As-syifaa Jurnal Farmasi The Spirit of Society Journal : International Journal of Society Development and Engagement Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Journal of Nutraceuticals and Herbal Medicine Pharmed: Journal of Pharmaceutical Science and Medical Research Jurnal Farmasi Indonesia Jurnal Jamu Indonesia Jurnal Ilmiah Farmasi Farmasyifa Jurnal Peduli Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian AL MA'ARIEF : JURNAL PENDIDIKAN SOSIAL DAN BUDAYA IJECS: Indonesian Journal of Empowerment and Community Services Jurnal Pengabdian Teknologi Tepat Guna Jurnal Farmasi Sains dan Praktis Borobudur Pharmacy Review Duta Pharma Journal Abdi Implementasi Pancasila: Jurnal Pengabdian kepada Masyarakat Jurnal Farmasetis Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Farmasi SYIFA SmartComp Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Nutraceuticals and Herbal Medicine
abdul, ahwan
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ANALISIS IN SILICO INTERAKSI SENYAWA KURKUMINOID TERHADAP ENZIM MAIN PROTEASE 6LU7 DARI SARS-COV-2 Ahwan abdul; Angkininta Ayu Winih Kinasih; Fadilah Qonitah
Duta Pharma Journal Vol. 3 No. 1 (2023): Duta Pharma Journal
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/djp.v3i1.2904

Abstract

Covid-19 merupakan penyakit yang disebabkan coronavirus jenis baru (SARS-CoV-2) di akhir tahun 2019. Sampai saat ini tidak ada obat khusus yang tersedia untuk mengobati penyakit ini. Pengobatan tradisional telah memainkan peran positif dalam memerangi Covid-19. Beberapa senyawa aktif mulai dilakukan penelitian untuk menangkal virus Covid-19 salah satunya adalah senyawa kurkumin. Kurkumin merupakan senyawa aktif dari tanaman kunyit dan temulawak. Berdasarkan penelitian dilaporkan kurkumin dapat menghambat agregasi trombosit, antidiabetes, antitumor, efek antiinflamasi, efek antioksidan, dan antivirus. Penelitian ini bertujuan untuk mengetahui interaksi antara senyawa kurkuminoid terhadap enzim main protease 6LU7 dari SARS CoV-2 serta senyawa kurkuminoid yang dapat berikatan dengan enzim main protease 6LU7 dari SARS CoV-2. Penelitian ini termasuk jenis penelitian eksperimental secara in silico. Hasil penelitian ini diperoleh senyawa uji kurkumin dan turunannya yaitu kurkumin, bisdemetoksikurkumin, dan demetoksikurkumin telah memenuhi syarat hukum Lipinksi Rule of Five. Bisdemetoksikurkumin memiliki kemampuan sebagai antivirus SARS-CoV-2 karena memiliki persamaan residu asam amino paling banyak dengan ligan pembanding (Favipiravir) yaitu residu ASN A:142; GLY A:143; CYS A:145; HIS A:163; HIS A:172; LEU A:141; SER A:144; GLU A:166; PHE A:140 dengan docking score sebesar -6,7 kkal/mol.
Implementasi Algoritma One Time Pad Untuk Enkripsi dan Dekripsi pada Peresepan Data Obat di Puskesmas Purwodiningratan Surakarta Farid Fitriyadi; Ahwan Ahwan
Smart Comp :Jurnalnya Orang Pintar Komputer Vol 12, No 4 (2023): Smart Comp: Jurnalnya Orang Pintar Komputer
Publisher : Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/smartcomp.v12i4.3958

Abstract

Puskesmas menurut  Peraturan Menteri Kesehatan Nomor 43 Tahun 2019 Tentang Pusat Kesehatan Masyarakat adalah suatu tempat yang digunakan untuk menyelenggarakan upaya pelayanan kesehatan, baik promotif, preventif,  kuratif  maupun  rehabilitatif  yang  dilakukan  oleh  pemerintah,  pemerintah  daerah dan/atau masyarakat. Puskesmas biasanya menyimpan obat-obatan di apotek sebelum diberikan/dijual kepada pasien. Resep obat merupakan sebuah permintaan tertulis dari dokter kepada seorang apoteker yang wajib dirahasiakan karena didalamya terdapat takaran dosis obat tertentu maupun jenis obat yang tidak boleh diketahui oleh sembarang orang, terutama bagi yang tidak berkepentingan. Banyaknya penyalahgunaan data yang sering terjadi sehingga menyebabkan kebocoran data pada pihak yang tidak bertanggung jawab, untuk itu diperlukan adanya suatu sistem yang dapat mengamankan data dalam bentuk enkripsi pada data obat sehingga hal tersebut meningkatkan keamanan informasi. Tujuan penelitian ini adalah untuk membuat sebuah aplikasi peresepan elektronik yang terenkripsi dengan menggunakan metode One Time Pad sehingga dapat meningkatkan keamanan data persepan obat. Algoritma One Time Pad yang merupakan salah satu jenis algoritma klasik dalam bidang kriptografi. Algoritma One Time Pad dapat melakukan proses enkripsi dan dekripsi. Hasil akhir dari penelitian ini adalah terbentukanya suatu sistem aplikasi presepan obat yang dapat berguna untuk mengamankan data dan informasi kepada pasien sehingga dapat terciptanya keamanan informasi pada data obat.
SKRINNING FITOKIMIA EKSTRAK ETANOL DAUN JERUK PURUT (Citrus hystrix) DARI KABUPATEN KLATEN Fadilah Qonitah; Reni Ariastuti; Ahwan; Pratiwi Maharani, Nurul Astia Wuri
GEMA Vol 34 No 01 (2022): GEMA
Publisher : LP3M

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kaffir lime leaves are used for traditional medicine and cosmetic ingredients. Phytochemical screening aims to provide information related to the class of compounds contained in the ethanol extract of kaffir lime leaves. The extraction process uses the maceration method with ethanol 96%. The components contained in the extract were analyzed by their compounds by colour test (qualitative) with several reagents for flavonoids, saponins, tannins, terpenoids, steroids, alkaloids, and essential oils. The results of the phytochemical screening test showed that the ethanol extract of kaffir lime leaves contained a class of flavonoid compounds, saponins, tannins, triterpenoids, alkaloids and essential oils
EFFECT OF TOTAL PHENOLIC AND TOTAL FLAVONOID LEVELS ON THE ANTIOXIDANT POWER OF WATER EXTRACT, ETHANOL AND CHLOROFORM OF GREEN TEA LEAVES (Camellia sinensis L) Ahwan Ahwan; Anik Suwarni; Reni Ariastuti; Rosyadah Hafidz; Sinta Mei Enjelina
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.940

Abstract

Tea (Camellia sinensis L.) was originally used as a refresh drink. Tea has many benefits, especially for health and beauty. The most widely used tea in the market is green tea, because its properties can be used as a daily drink to improve the quality of life in carrying out daily activities. The aim of this study was to determine the effect of the relationship between total phenolic and total flavonoid levels in water extract (EA), ethanol (EE), and chlorophorom (EK) of green tea leaves on antioxidant power. This experimental study used the extraction method, qualitative analysis, quantitative analysis using the colorimetric method, and antioxidant power using the DPPH method. The data obtained were statistically analyzed using SPPS and Microsoft Excel. The results obtained in The extraction process yielded extracts: EA (21.44%), EE (11.20 %), and EK (3.58 %). Qualitative analysis of flavonoid and phenolic compounds in all the extracts revealed the presence of these compounds. In the total phenolic test, the levels were: 229.07 ± 0.99 (EA); 573.70 ± 3.93 (EE); 45.27 ± 0.73 mg/g (EK) GAE (Galic Acid Equivalent). Meanwhile, the flavonoid content was 13.10 ± 0.31 (EA); 40.49 ± 0.67 (EE); 20.94 ± 0.50 mg/g (EK) QE (Quercetin Equivalent). The antioxidant results have an IC50 (Inhibitory Concentration) value of 34.64 ± 0.74 (EA); 7.02 ± 0.15 (EE); 99.11 ± 1.23; positive control 5.94 ± 0.07 µg/mL (vitamin C) ...
The Value of the Diagonal Shear Stress of the Masonry on Laboratory Testing Marwahyudi, Marwahyudi; Rifai, Muhammad Dian; Ahwan, Ahwan; Arifin, Muhammad Yusuf; Shafyna, Ganaia Laisya; Allai, Danang Yuli
THE SPIRIT OF SOCIETY JOURNAL : International Journal of Society Development and Engagement Vol 7 No 1: September 2023
Publisher : LPPM of NAROTAMA UNIVERSITY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29138/scj.v7i1.2451

Abstract

The earthquake resulted in structural, non-structural damage, material and non-material losses and even death. Material losses in the form of damage to houses, household furniture, loss of property. Non-material losses in the form of loss of peace, comfort. The above damage is anticipated by increasing the brick wall elements which contribute well to increasing its capacity to carry the combined external forces that occur during the earthquake. In particular, increasing the strength of a brick wall can be done by selecting the quality of the wall constituent materials and designing the brick wall. This research is addressed to investigate the value of the diagonal shear stress of the masonry brick due to the external forces. The testing was carried out as laboratory testing by using the preference model and method. The results of this study is that normal bricks reach 1500 to 1800 Kgf, and the normal diagonal shear stress reaches 1.6603788 Kg/cm2, while initial cracking at 400 to 800 Kgf, later cracking at 800 to 1,000 Kgf and failing at 1,500 – 1,800 Kgf.
Gambaran Penggunaan Obat Analgetik NSAID Di Apotek Hidayah Metro Lampung Periode Januari-Desember 2022 Dahlia, Ajeng; Abdul, Ahwan; Ariastuti, Reni
Borobudur Pharmacy Review Vol 3 No 2 (2023): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v3i2.10354

Abstract

Analgetik NSAID adalah obat yang digunakan untuk mengurangi peradangan, meredakan nyeri, dan menurunkan demam. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan obat analgetik NSAID di Apotek Hidayah Metro Lampung periode Januari – Desember 2023, metode penelitian menggunakan desain deskriptif kualitatif yang diperoleh dari observasi langsung dan pengambilan data secara retrospektif. Sampel penelitian yang digunakan sejumlah 40.056 sediaan. Hasil penelitian didapatkan persentase penggunaan obat NSAID bermerk lebih banyak 31.194 (77,88 %) sediaan dibandingkan analgetik NSAID generik 8.862 (22,12 %) sediaan. Penggunaan analgetik NSAID bermerk lebih banyak secara non resep 31.156 (99,88 %) sediaan, dengan isi zat aktif asam mefenamat 9.149 (29,37 %) sediaan, golongan oksikam 9.430 (30,27 %) sediaan dengan mekanisme kerja nonselektif (COX) 29.306 (94,06 %) sediaan dan berbentuk tablet 29.568 (94,90 %). Penggunaan analgetik NSAID generik lebih banyak secara non resep 8.647 (97,57 %) sediaan, obat yang digunakan piroxicam 3.120 (36,08 %) sediaan, golongan oksikam 3.760 (43,48 %) sediaan dengan mekanisme kerja nonselektif (COX) 7.147 (82,65 %) sediaan, dan berbentuk tablet 29.568 (94,90 %). Kesimpulan: Hasil penelitian ini didapatkan penggunaan analgetik NSAID bermerk lebih banyak, pembelian tanpa resep dokter, obat NSAID dengan isi zat aktif asam mefenamat dan berbentuk tablet yang bekerja secara nonselektif.
Uji Skrining Fitokimia Ekstrak Etanol 96% Daun Markisa Ungu (Passiflora edulis Sims) Septiningrum, Chintya Hayu; Ariastuti, Reni; Ahwan, Ahwan
Jurnal Farmasi SYIFA Vol 2 No 2 (2024): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v2i2.430

Abstract

Markisa ungu (Passiflora edulis Sims) diketahui mengandung senyawa bioaktif yang berpotensi sebagai antioksidan seperti karotenoid, antosianin, flavonoid, dan vitamin C. Daun markisa ungu (Passiflora edulis Sims) telah diketahui memiliki kandungan senyawa flavonoid. Skrining fitokimia pada penelitian ini bertujuan untuk mengetahui kandungan senyawa metabolit sekunder pada ekstrak etanol daun markisa ungu. Metode penelitian yang digunakan yaitu eksperimen laboraturium. Penelitian ini dilakukan dengan beberapa proses yaitu penyiapan simplisia, ekstraksi simplisia menggunakan metode maserasi dengan etanol 96%, dan skrining fitokimia. Berdasarkan penelitian dapat disimpulkan bahwa ekstrak etanol daun markisa ungu (Passiflora edulis Sims) positif mengandung senyawa flavonoid, fenolik, tanin, saponin, alkaloid, dan steroid.
Uji Daya Hambat Antibakteri Ekstrak Air, Etanol, Dan Kloroform Daun Teh Hijau (Camellia Sinensis L. Kuntze) Terhadap Pertumbuhan Bakteri Escherichia Coli Ghaliyah Hidastri Rukmana; Ahwan; Fadilah Qonita
An-Najat Vol. 2 No. 4 (2024): NOVEMBER - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i4.1680

Abstract

Infection is a major disease problem in the world, especially in Indonesia. One of the bacteria that causes infection is Escherichia coli. A common symptom of infection is diarrhea, infection can be treated using antibiotics. Antibacterial compounds derived from plant extracts are green tea leaves (Camellia Sinensis L. Kuntze). This study aims to determine the differences in the inhibitory power tests of water, ethanol and chloroform extracts of green tea leaves (Camellia Sinensis L. Kuntze) against bacterial growth Escherichia coli. In antibacterial testing, the disc diffusion method is used, and the data is processed using the test Oneway ANOVA. The test results showed that all samples had antibacterial activity. The strong inhibitory category is owned by ethanol extract of green tea leaves with a concentration of 16% (13.23 ± 0.10) mm and 64% (18.35 ± 0.05) mm, chloroform 16% (11.38 ± 0.19 ) mm and 64%, (13.48 ± 0.24) mm, water 64% (12.25 ± 0.05) mm. The moderate inhibitory power category belongs to water extract concentrations of 4% (7.87 ± 0.08) and 16% (8.45 ± 0.22) mm. Meanwhile, the positive control of 3% chloramphenicol has a very strong inhibitory power with an average zone of inhibition of (29.38 ± 0.15) mm, and the weak inhibitory power of the negative control of 1% DMSO is (0 ± 0.00) mm. . Based on the research results, it can be concluded that the three extracts of water, ethanol and chloroform were proven to have antibacterial activity against Escherichia coli which is significantly different (p value) < 0,05.
Aktivitas Antibakteri Ekstrak Air, Etanol, Kloroform Teh Hijau (Camelia Sinensis L.) Terhadap Pertumbuhan Stophylococcus Epidermis Salwa Pratiwi; Ahwan; Fadilah Qonitah
An-Najat Vol. 2 No. 4 (2024): NOVEMBER - An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i4.1691

Abstract

Acne is a skin condition that often occurs on the face, neck, chest, and back. The oil glands in the skin are very active, causing the skin pores to become clogged with fat deposits. One of the factors causing acne is Staphylococcus epidermis bacterial infection, and skin conditions. Alternative treatments used are plants that have benefits as antibacterials. This study was experimental in nature, the aim of which was to determine the differences in the antibacterial activity test of Water Extract (EA), Ethanol Extract (EE), and Chloroform Extract (EK) of green tea leaves (Camellia Sinensis.L) against the growth of Staphylococcus epidermis bacteria. The disc diffusion method was used in testing antibacterial activity. The results showed that each positive extract had antibacterial activity against Staphylococcus epidermis bacteria with different levels of inhibition. The strong inhibition category is owned by EE 40% (12.41 ± 0.20) mm, EE 60% (14.4 ± 0.23) mm, EK 40% (11.5 ± 0.31) mm, and EK 60% (13.3 ± 0.1) mm. The moderate inhibition category is owned by EA 10%, (6.38 ± 0.15), EA 40% (8.53 ± 0.28), EA 60% (9.36 ± 0.21), EE 10% (9.76 ± 0.18) mm, and EK 10% (7.38 ± 0.20) mm. Meanwhile, the positive control of clindamycin 1.5% had a very strong inhibitory power with an average of (30.83 ± 0.10) mm, and the negative control of DMSO 1% had a weak inhibitory power of (0.00 ± 0.00). Based on the results of the study, it can be concluded that water, ethanol and chloroform extracts of green tea leaves have been proven to have antibacterial activity against Staphylococcus epidermis bacteria which are significantly different (p value 0.000 <0.05).
A comparison of Islamic religious practices in Pakistan and Indonesia: A sociocultural perspective Wijianto, Diski Wahyu; Arini Nur Yunia Puspitaningrum Rahmwati; Hidayah Kurniawati; Peni Indrayudha; Tri Yulianti; Ahwan Abdul; Muhammad Ajmal Shah
AL MA'ARIEF : Jurnal Pendidikan Sosial dan Budaya Vol 6 No 2 (2024): Al Ma'arief: Jurnal Pendidikan Sosial dan Budaya
Publisher : Program Studi Tadris IPS Institut Agama Islam Negeri (IAIN) Parepare

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35905/almaarief.v6i2.11638

Abstract

Islam is the majority religion in both Pakistan and Indonesia, the two countries with the largest Muslim populations in the world. While both uphold Islam as the primary faith, religious practices in each country are influenced by differing historical, social, and cultural contexts. This article compares Islamic religious practices in these two nations from a socio-cultural perspective. The research method utilized includes a lecture delivered by Assist. Prof. Muhammad Ajmal Shah, an academic and practitioner from Pakistan. The analysis covers various aspects, such as the size of the Muslim population, the application of Sharia law, variations in Islamic sects and practices, and the interplay between religion and politics. The findings indicate that in Pakistan, Islam serves as a foundational basis for policymaking and national identity, with stricter implementation of Sharia law. In contrast, Indonesia integrates Islamic law with customary and secular laws within a pluralistic framework. Both countries face challenges in maintaining religious tolerance and social stability amidst globalization and modernization. The study concludes that despite differences in the implementation of Islamic law and politics, religion continues to play a significant role in both countries, presenting challenges and opportunities to uphold societal harmony.
Co-Authors Allai, Danang Yuli Angkininta Ayu Winih Kinasih Anik Suwarni Ariastuti, Reni Arifin, Muhammad Yusuf Arini Nur Yunia Puspitaningrum Rahmwati Arinta Mayang Chairunnisa, Alya Dahlia, Ajeng Dian Muhammad Rifai Fadilah Qonita Fadilah Qonitah Fadilah Qonitah Fadilah Qonitah Fadilah Qonitah Fadilah Qonitah Farid Fitriyadi Ghaliyah Hidastri Rukmana Haryoto Haryoto Hidayah Kurniawati Marilis Rosana Marwahyudi Marwahyudi Muhammad Ajmal Shah Musta’an Musta’an Musta’an Musta’an Nuning Nurhayati Partonowati _ Peni Indrayudha Pratiwi Maharani, Nurul Astia Wuri Raden Roro Karina Pambudi Reni Ariastuti Reni Ariastuti Reni Ariastuti Rifai, Muhammad Dian Rosyadah Hafidz Sakti Pambudi, Risma Salwa Pratiwi Santoso, Bilal Subchan Agus Septiningrum, Chintya Hayu Shafyna, Ganaia Laisya Sinta Mei Enjelina Sukma Shinta Yunianti Sulis Fajarwati Susi Rahmawati Syahnaz Sanjiwani Agatha Ruth Mahawikan Syaifur Rahman Tri Yulianti Uswatun Hasana Wijianto, Diski Wahyu _, Partonowati