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Gambaran Potensi Interaksi Obat Hipoglikemia Oral (OHO) dengan Obat Lain pada Pasien Diabetes Mellitus Tipe II di Puskesmas Pajang sofia, Sofia alvani kambayong; Sakti Pambudi, Risma
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 2 No. 2 (2024): Bulan November 2024 Faskes : Jurnal Farmasi, Kesehatan, dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v2i2.3298

Abstract

Latar Belakang : Diabetes Mellitus (DM) merupakan gangguan metabolisme yang ditandai dengan tingginya kadar gula darah karena gangguan produksi insulin. Diabetes Mellitus juga mempunyai komplikasi sehingga menimbulkan kematian, komplikasi yang muncul yaitu makrovaskuler dan mikrovaskuler. Tujuan : penelitian ini yaitu melihat pemahaman masyarakat tentang gambaran potensi interaksi OHO (Obat Hipoglikemia Oral) dengan obat lain pada pasien Diabetes Mellitus Tipe II di Puskesmas Pajang. Metode : Penelitian ini bersifat deskriptif dengan mengambil data secara restrospektif. Data penelitian akan dilakukan analisis interaksi obat OHO dengan kombinasi terapi obat lainnya berdasarkan Drug Interaction Cheker. Hasil : penelitian menunjukan bahwa profil pengunaan obat hipoglikemia oral (OHO)158 obat yang terdiri dari metformin 84 obat, glimepiride 72 obat dan glibenklamid 2 obat dan obat non hipoglikemia oral (Non OHO) 260 obat yaitu amlodipin 58 obat, natrium dsiklofenat 27 obat dan simvastatin 24 obat. Berdasarkan penelitian yang dilakukan maka Kesimpulan dan Saran : profil penggunaan obat yang diperoleh yaitu OHO  158 obat (37,79%) non OHO 260 obat (62,20%), Interaksi obat secara farmakokinetik sebanyak 8 kejadian (11,59%), farmakodinamik sebanyak 61 kejadian (88,40%) dan jenis mekanisme interaksi obat berdasarkan signifikansi yaitu minor sebanyak 31 kejadian (44,92%), moderate 38 kejadian (55,07%).
Antidiabetic Activities and Phytochemical Screening of Broccoli Plants (Brassica oleracea L. var. italica) Chairunnisa, Alya; Haryoto, Haryoto; Abdul, Ahwan
Journal of Nutraceuticals and Herbal Medicine Vol 5, No 1 (2024): JNHM 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jnhm.v5i1.3705

Abstract

Diabetes mellitus is a metabolic disease that is characterized by hyperglycemia which is closely related to pancreatic β cell dysfunction and insulin resistance. Brassica oleracea L. var. italica is a member of the Brassicaceae family which has antidiabetic properties. These effects are caused by the presence of various phytochemical compounds in broccoli plants, flavonoids, tannins, saponins, alkaloids, steroids, glucosinolates, isothiocyanates, and phenolics. The aim of this review is to find out the antidiabetic activity of broccoli plants and the mechanism of action of phytochemical compounds in broccoli plants that support these benefits. The preparation of this review was sourced from articles obtained from the PubMed and Google Scholar databases with the interval 2012-2021 publication year. Based on the selected articles, it shows that the content of phytochemical compounds in broccoli plants has an effect on reducing blood sugar levels through various mechanisms. Therefore, the results of this study are expected to be used as support for the use of broccoli plants as antidiabetic agents.
The Use of Herbal Medicine and Medicinal Plants as Immunity Enhancers for Migrant Workers in Malaysia by Utilizing Herbal Plants Around the House as Body Immune Enhancers ahwan, ahwan
JURNAL PENGABDIAN TEKNOLOGI TEPAT GUNA Vol 6 No 1 (2025): Teknologi Tepat Guna (TTG)
Publisher : Universitas Sahid Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47942/jpttg.v6i1.1966

Abstract

Indonesian migrant workers in Malaysia face various challenges, including limited access to health services and vulnerability to diseases due to demanding working conditions and unfamiliar environments. This community service aims to increase knowledge and skills regarding the use of traditional medicinal plants to improve immunity. The method used is to provide training materials on identifying, processing, and consuming available medicinal plants safely. Evaluation of this community service activity showed an increase in participants' knowledge about traditional medicine, its benefits, and safe use practices. The long-term goal is to encourage sustainable practices in utilizing local herbal resources for self-care among PMI in Malaysia, which contributes to their overall health, productivity, and well-being while preserving traditional Indonesian medicinal practices.