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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Sains dan Komunitas Jurnal Penelitian Farmasi Indonesia Jurnal Kreativitas PKM Jurnal Farmasi Higea Jurnal Farmamedika (Pharmamedica Journal) Jurnal Riset Kefarmasian Indonesia Borneo Journal Of Pharmascientech Journal SAGO Gizi dan Kesehatan Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Jurnal Farmasi Indonesia Inovasi Jurnal Pengabdian Masyarakat (IJPM) Jurnal Pengabdian Masyarakat Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Pratiwi, Erniza
Sekolah Tinggi Ilmu Farmasi Riau
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Evaluasi kuantitatif penggunaan antipsikotik pada pasien skizofrenia dengan metode ATC/DDD dan DU 90% di RSJ Tampan Provinsi Riau tahun 2023 Novia Sinata; Defrika Dian Tami; Erniza Pratiwi
Jurnal SAGO Gizi dan Kesehatan Vol 7, No 2 (2026): Agustus
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v7i2.3004

Abstract

Background: Schizophrenia is a major cause of disability, and antipsychotics are the main pharmacological treatment. Their use requires evaluation because adverse effects may affect treatment safety and adherence. Antipsychotic utilization among inpatients at RSJ Tampan has not previously been evaluated using the World Health Organization (WHO) ATC/DDD and DU 90% methods.Objectives: This study aimed to quantitatively evaluate antipsychotic utilization among inpatients with schizophrenia using the ATC/DDD and DU 90% methods.Methods: This descriptive observational study used a retrospective review of medical records from January to December 2023. A total of 101 records that met the eligibility criteria were selected through purposive sampling. Antipsychotic utilization was calculated as defined daily doses (DDD) per 100 bed-days. Drugs were ranked by utilization volume, and cumulative percentages were used to identify the DU 90% segment.Results: Total antipsychotic utilization was 123.82 DDD/100 bed-days and was dominated by typical antipsychotics. Five drugs comprised the DU 90% segment: haloperidol (74.58 DDD/100 bed-days; 60.23%), risperidone (14.95; 12.07%), aripiprazole (14.42; 11.65%), fluphenazine (5.36; 4.33%), and trifluoperazine (4.73; 3.82%), with a cumulative proportion of 92.10%.Conclusion: Antipsychotic utilization was concentrated in five drugs, with haloperidol accounting for the largest proportion. These quantitative findings support further evaluation of prescribing appropriateness and treatment safety.
Co-Authors ., Nofriyanti agistia, nesa Agistia, Nesa Anggraini, Laurentin Leni Azizah, Mifza Azizah, Wahyu Deddi Prima Putra Defrika Dian Tami Deswinda, Intan Ayu Devi Safitri Dinda Farahdilla Farel Anugrah Ferdy Firmansyah Furi, Mustika Haiyul Fadhli Hidayati, Fika Husnawati Husnawati Husnawati Husnawati Ihsan Ikhtiarudin Indah Lestari, Indah Indah Wahyuni Indriyati Hadi Sulistyaningrum Iswari, Yuwanda Jumira Jumira Laia, Cindy Oktaviana Laura Syahrul Lestari, Kurnia Dwi Maqfiroh, Wirdarani Mardianti, Tengku Shella Meiriza Djohari, Meiriza Mifza Azizah Muhammad Thesa Ghozali Musyirna Rahmah Nst Muti’ah, Try Hadirah Nofriyanti Nofriyanti Nouval Zamra Prasojo Pribadi Putri, Sella Hilmalia Nur Al Putri, Wulandari Yulia Rahmatunnur, Siti Rahmi, Helvy Ramadhan, Fariz Putra Ratna Sari Dewi Rifani, Mhd Rosidi, Fatmarzuqni Putri Sastrawati, Atriwida Septi Muharni septia roza Shelna, Khafiza Sinata, Novia Sumbarita, Silvia Wulan Sari Firmes Putri Yuwanda Iswari Zahira, Rifka Zamri, Wiedya Alfitrya