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All Journal Majalah Farmasetika Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Lumbung Farmasi : Jurnal Ilmu Kefarmasian Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Insan Farmasi Indonesia Jurnal Farmasi Jurnal Buana Farma Binawan Student Journal Parapemikir Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian
Chandra, Pra Panca Bayu
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Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Journal : Jurnal Buana Farma

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LITERATURE REVIEW: POTENSI OBAT BAHAN ALAM DARI TANAMAN SEMANGGI AIR (Marsilea crenata) Chandra, Pra Panca Bayu; Laksmitawati, Dian Ratih
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1383

Abstract

The use of plants as natural medicine is used because Indonesia has a wealth of natural resources. One of the plants used is water clover (Marsilea crenata). This plant is used as food and medicine. This study aims to identify the potential of natural medicine from water clover (Marsilea crenata). The research method in the literature study is to apply journal searches to the Google Scholar, Science Direct, and Pubmed databases with the keywords water clover (Marsilea crenata) and pharmacological activity. The journals used are national and international journals published from 2012 to 2025. The journals used are research on the potential of water clover as a natural medicine in silico, in vitro and in vivo. From the results of the literature study, 9 journals were obtained. After obtaining research data from journals, they were then combined and studied, then explained and explained systematically. The results of the study showed that water clover leaves in both extract and fraction forms have pharmacological activities including anticholesterolemia, antihyperglycemia, antioxidant, anti-inflammatory, HMG-CoA reductase enzyme inhibitory activity, sperm quality improvement activity in hyperglycemic mice, anti-neuroinflammatory serum. The content of secondary metabolites found in Marsilea crenata is a bioactive compound that is responsible for providing pharmacological activity.
AKTIVITAS ANTIJAMUR EKSTRAK ETANOL DAUN KARI TERHADAP Candida albicans ATCC 14053 Sari, Putri Eka; Chandra, Pra Panca Bayu; Lisnawati, Nia; Ami, Neng
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1400

Abstract

Medicinal plants are recognized as valuable sources of secondary metabolites with therapeutic potential. Candidiasis caused by Candida albicans is a common health problem in tropical regions. The prolonged use of synthetic antifungal agents may lead to resistance, highlighting the need for effective natural alternatives. Curry leaves (Murraya koenigii (L) Spreng) are known to contain flavonoids and alkaloids with potential antifungal activity. This study aimed to evaluate the antifungal activity of the 96% ethanol extract of curry leaves against Candida albicans ATCC 14503. The extract was prepared by maceration using 96% ethanol as the solvent. Phytochemical screening revealed the presence of flavonoids and saponins. The antifungal activity was tested using the disc diffusion method at concentrations of 6,25%, 12,5%, 25%, and 50%. Ketoconazole was used as positive control, while 96% ethanol served as a negative control. The test was performed in triplicate, and the inhibition zones were measured and averaged. The results showed that the 96% ethanol extract of curry leaves at all tested concentrations did not exhibited antifungal activity against C. albicans as indicated by the absence of inhibition zones on the media. It can be concluded that the extract, under the given conditions, was not effective in inhibiting fungal growth. This suggests that the extraction method and tested concentrations may not have been sufficient to isolate or concentrate the active compounds. Further studies using alternative extraction techniques, higher concentrations or isolated compounds are needed to better evaluate the antifungal potential of M. koenigii.
Co-Authors Adini, Syilvi Ami, Neng Dian Ratih Laksmitawati Efrilia, Mega Endrawati, Santi Falestin , Senny Listy Kartika Falestin, Senny Listy Kartika Handayani, Indri Astuti Hermawati, Ema Ismyama, Dian Farida Lisnawati, Nia Loimalitna, Pricillya Maria Meryta, Aries PUTRI EKA SARI, PUTRI EKA Putri, Weni Pratiwi Qodriah, Rahmatul Sabrina, Alifa Shobah, Afifah Nur Tan, Ardy Tanfil Whardhani, Sabrina K. Yulius Evan Christian