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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) E-Jurnal Medika Udayana Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Manuju : Malahayati Nursing Journal Jurnal Farmasi Indonesia Jurnal Karinov Jurnal Farmagazine Jurnal Ilmiah Medicamento Poltekita: Jurnal Pengabdian Masyarakat Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Pengabdian kepada Masyarakat Jurnal Farmasi Indonesia Usadha
Debby Juliadi
UNIVERSITAS MAHASARASWATI DENPASAR
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Usadha

 1 
Formulasi Dan Uji Mutu Fisik Dari Granul Effervescent Ekstrak Daun Salam (Syzyginum polyanthum) Dewi, Ni Luh Samila; Suradnyana, I Gede Made; Juliadi, Debby
Usadha Vol 3 No 2 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i2.7180

Abstract

  Bay leaf is one plant that has benefits as traditional medicine, acting as an antioxidant with flavonoid content. The processing is still very simple, which has an impact on the short shelf life of the herb. One alternative to prevent this is to formulat e bay leaf extract into effervescent granule preparations, which provide a more comfortable feeling with a large concentration of active substances. This study aims to determine the difference in the physical quality of effervescent granule preparations wit h variations of effervescent salts and to determine the concentration of acids and bases that produce effervescent granules of bay leaf extract with good physical quality. In 3 effervescent granule preparation formulas, the variation in acid and base concentrations (citric acid, tartric acid, and sodium bicarbonate) is F1 by 9.4%; 18.7%; 27%, F2 by 8.6%; 17.2%; 29%, and F3 by 7.9%; 15.8%; 31%. Physical quality evaluation of effervescent granule preparations includes organoleptis, flow velocity, rest angle, disperse time, pH, and moisture content. Quantitative data were analyzed with the One Way Anova test to determine the difference in physical quality of the three effervescent granule preparation formulas. Based on the results of physical quality tests, the three greenish-white granule formulas were obtained, the characteristic smell of bay leaf extract, and the granule form with a flow speed of 10 g / second, a stati onary angle in the range of 31-35 °, a dispersion time of < 5 minutes, a pH in the range of 5-6, and a moisture content of < 5 minutes. The results of One Way Anova testing found that the three formulas with variations of effervescent salts have different physical qualities, and acid-base concentrations that produce good physical qualities, namely F1 and F3
Formulasi dan Uji Mutu Fisik Sediaan Lip Balm Ekstrak Umbi Bit (Beta vulgaris L.) Tiarini, Diah Galuh; Suradnyana, I Gede Made; Juliadi, Debby
Usadha Vol 3 No 3 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i3.7181

Abstract

Dry and chapped lips are one of the problems often faced by some people that will cause pain and discomfort. Lip balm is made from the main ingredient oil or fat that will provide moisture to the lips. The addition of color to lip balm preparations will add its own attractiveness, especially for women, because occasionally it can help improve facial aesthetics. Beetroot (Beta vulgaris L.) It is one of the plants that contains betacyanin pigment which has the potential as a natural dye and has very strong antioxidant activity. The purpose of this study was to determine whether there was a difference in the physical quality of lip balm preparations with variations in beetroot extract (Beta vulgaris L). This research is a laboratory study by formulating beetroot ethanol extract into lip balm preparations in 3 formulas with variations in extract concentration, namely formula I (6%), formula II (10%), and formula III (14%). Physical quality tests of the preparations observed are organoleptis, homogeneity, adhesion, and dispersion. Analysis of organoleptical data and homogeneity was carried out descriptively while the results of adhesion and dispersion tests were analyzed with inferential statistics using IBM SPSS statistics 26 at a 95% confidence level with the One-Way ANOVA test. The results of this study showed that there were differences in the physical quality of beetroot extract lip balm (Beta vulgaris L.) at a FI (6%) with a FII (10%) and FIII (14%) especially in the dosage color, adhesion, and spreadability.
Formulasi Dan Evaluasi Mutu Fisik Granul Ekstrak Etanol Kunyit Putih (Curcuma zedoaria) Dengan Variasi Konsentrasi Bahan Pengikat Polivinil Pirolidon Apriliani, Wayan; Juliadi, Debby; Suradnyana, I Gede Made
Usadha Vol 3 No 2 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i2.7578

Abstract

  White turmeric (Curcuma zedoaria) is a medicinal plant that Indonesian people widely use as a treatment for a disease. This plant is processed by blending it and serving it as a traditional medicine. However, the method of processing which is still very traditional allows errors in processing to make the efficacy of white turmeric not optimal, besides that the preparations that are processed cannot be used for a long time. Granule is a solid dosage form intended for oral use, the advantage of this preparation is the flexible dosage weight which allows for the formulation of large amounts of active ingredients such as most extracts. This study aims to obtain white turmeric ethanol extract granules with varying concentrations of polyvinyl pyrrolidone, namely 1%, 3%, and 5% which have good physical quality. The test results from this study showed that the physical quality of the preparation was good, in which the organoleptic preparation obtained was light yellow, smelled of orange aroma, and granular form. The granule compressibility test of the three formulas complied with the requirements because it was <20%. The granule flow rate test showed that the three formulas met the requirements, namely >10 gram/second. Test angle of repose of the three formula granules meet the requirements> 40o. The granule soluble time test showed that the three formulas met the requirements, namely <5 minutes and the granule water content test of the three formulas met the requirements, namely <5%. Polyvinyl pyrrolidone (PVP) binders with concentrations of 1%, 3%, and 5% produced good granules.
Review: Pemanfaatan Tanaman sebagai Fitoterapi pada Diabetes Mellitus Dewi, Ni Luh Kade Arman Anita; Prameswari, Putu Nimas Diyah; Cahyaningsih, Erna; Megawati, Fitria; Agustini, Ni Putu Dewi; Juliadi, Debby
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5562

Abstract

Diabetes is a chronic disease that occurs due to high levels of sugar in the blood, this can occur when the pancreas does not produce enough insulin (a hormone that regulates blood sugar or glucose), or when the body cannot effectively use the insulin it produces. Management of DM patients can be carried out with non-pharmacological and pharmacological therapies. The method used in the journal review was to search for the keyword "diabetes mellitus herbal medicine" for clinical studies on plant-derived products for the treatment of diabetes mellitus. Search terms included “phytotherapy”, “phytochemicals”, “medicinal plant products”, “herbal medicine”, and “diabetes mellitus”. Involving plant-derived compounds and pigmentation as outcome measures were included. In this review article, 30 journals were collected from which the objectives and results of the research in the journal were obtained. The goal is as an alternative management treatment to control blood sugar levels. For some of the compounds we discuss, among others: Flavonoids, Allicin, Lectins, Alkaloids, Andrographolid, Curcumin, Cinnamaldehyde, peptides, Phenolics, Tannins.
Formulasi Dan Uji Mutu Fisik Sediaan Foot Lotion Ekstrak Etanol Daun Sirih (Piper bettle L.) Dengan Variasi Konsentrasi Asam Stearat Juliadi, Debby; Juanita, Rr Asih; Dewi Agustini, Ni Putu
Usadha Vol 2 No 1 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.6420

Abstract

Betel leaf extract (Piper bettle L.) is known to contain flavonoid compounds that have antibacterial activity. Betel leaf extract needs to be formulated as a foot preparation lotion to increase the comfort of use as a topical antibacterial. The composition of the emulsifier influences the physical stability of the preparation foot lotion used. This study aims to determine the variation of stearic acid preparations foot lotion, which has good physical quality and is stable in storage. This research is purely experimental laboratory research that aims at development (development), namely developing something in an existing field (development of test methods, drug formulation). The observed responses were the physical quality of the preparations, which included organoleptic tests, homogeneity tests, pH tests, spreadability tests, and adhesion tests. The physical quality of preparations of foot lotion was analyzed descriptively. This research began with a maceration process using 70% ethanol to obtain a thick betel leaf extract (Piper bettle L.). This study made three preparation formulas with foot lotion with stearic acid concentrations of 10%, 12.5%, and 15%. The preparations that have been made are then tested for their physical quality and stability during four weeks of storage. The results of this study indicate that the preparations obtained foot lotion betel leaf ethanol extract (Piper bettle L.) with a variation of stearic acid of 10% to produce preparations of foot lotion with good physical quality seen from organoleptic tests, homogeneity, pH, spreadability, and adhesion and stable in storage for four weeks.
Tingkat Pengetahuan Penggunaan Tanaman Obat Tradisional Sebagai Alternatif Pengobatan Pada Masyarakat Desa Wisata Bindu Dewi Agustini, Ni Putu; Megawati, Fitria; Juliadi, Debby; Widiari, Ni Nyoman Sri
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7145

Abstract

Public knowledge about the use of plants as medicine is mostly limited to hereditary knowledge as a form of interaction between the community and the environment, especially plants. Currently medicinal plants or herbal plants have been widely used in the medical or health fields. Today's society prefers to use products that come from nature for safety reasons. This study aims to determine the level of knowledge of the use of traditional medicine as an alternative treatment in the community of Bindu Tourism Village. The research method used is a descriptive survey method with a cross-sectional design where the research object is only observed once without any pre-test and post-test with data collection techniques using questionnaires distributed via online in Bindu Tourism Village. The data obtained from the research results were then processed by calculating the percentage of respondent answers. The results of the questionnaire data analysis obtained from 104 respondents showed that the people who had a good level of knowledge were 51 people (49%), 46 people (44%), and the level of knowledge in the poor category were 7 people (7%). The average value of knowledge from 104 respondents is 77% which is included in the range (76%-100%), so the level of knowledge of respondents is good.
Formulasi Dan Uji Mutu Fisik Ekstrak Etanol Rimpang Kunyit Putih (Curcuma Zedoaria) Pada Sediaan Tablet Dengan Variasi Bahan Polivinil Pirolidon Dan Starch 1500 Rika, Putu; Juliadi, Debby; Putra, I Made Agus Sunadi
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7363

Abstract

The white turmeric plant (Curcuma zedoaria) is a species from the Zingiberaceae family which is very important in traditional medicine and the medicinal industry. Apart from being used as a food or beverage ingredient, white turmeric is also used as a traditional medicine, such as stomach ache medicine, stomach booster, fever reducer and can treat skin diseases. This study aims to determine the effect of the concentration of polyvinyl pyrrolidone binder and starch 1500 disintegrating agent on the physical properties of tablets and to obtain a white turmeric rhizome ethanol extract tablet formula which has the best physical quality test. The method used in the manufacture of tablets is the wet granulation method, because this method can improve flow properties and increase compressibility. The results of this study on the physical quality testing of FI and FIII tablets have fulfilled the physical quality test requirements for tablets, but FII has not fulfilled the physical quality test requirements for tablet preparations because FII does not meet the disintegration time test requirements, this is influenced by the concentration of polyvinyl pyrrolidone binder (PVP) was higher than Starch 1500 disintegrant. In this study, FIII had the best physical quality test, where FIII was a physical quality test and had the fastest tablet disintegration time, which was 10 minutes. This is influenced by the higher concentration of Starch 1500 disintegrant, which is 8% compared to the polyvinyl pyrrolidone (PVP) binder, which is 5%.
Co-Authors Agustini, Ni Putu Dewi Apriliani, Wayan Astya Putri, Ni Kadek Dita Darmawan, I Wayan Agus Dewa Ayu Ika Pramitha Dewi Agustini, Ni Putu Dewi, Kade Ayu Yasinta Dewi, Ni Luh Samila Erna Cahyaningsih I Gede Made Suradnyana I Gede Made Suradnyana Suradnyana I Gede Yodhi Trismawan I Putu Pasek Jaya Separsa Ida Ayu Gede Syntya Mahayani Kade Ayu Yasinta Dewi Kadek Desy Aryantini Ketut Agus Adrianta Luh Tuti Suryati Megawati, Fitria Mendra, Ni Nyoman Yudianti Ni Luh Kade Arman Anita Dewi Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Nyoman Wahyu Udayani Ni Nyoman Yudianti Mendra Ni Putu Dewi Agustini Ni Putu Udayana Antari Ni Wayan Yuliasih Novita Dewi Nyoman Budiartha Siada Prameswari, Putu Nimas Diyah Pratiwi, Dewa Ayu Yunika Puguh Santoso puguh santoso, puguh Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putri, Ni Kadek Dila Pratiwi Putri, Ni Kadek Nisa Leoni Putu Era Sandhi Kusuma Yuda Rika, Putu RR. Asih Juanita Sasadara, Maria Malida Vernandes Suradnyana, I Gede Made Tiarini, Diah Galuh Wardani, I Gusti Agung Ayu Kusuma Widiari, Ni Nyoman Sri Yanti, Ni Kadek Pradnya Yuliasih, Ni Wayan