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All Journal Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Nasional Komputasi dan Teknologi Informasi JISIP: Jurnal Ilmu Sosial dan Pendidikan Pharmaceutical Journal of Indonesia Stannum : Jurnal Sains dan Terapan Kimia Aksara: Jurnal Ilmu Pendidikan Nonformal Community Development Journal: Jurnal Pengabdian Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Insan Farmasi Indonesia Journal of Vocational Nursing Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal of Scientific Research, Education, and Technology Journal of Pharmaceutical and Sciences.
emelda, emelda
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Journal : Journal of Pharmaceutical and Sciences.

 1 
Pengaruh variasi konsentrasi terhadap uji sifat fisik dan stabilitas freeze- thaw cycling pada formula sediaan gel kombinasi ekstrak daun kelor dan ekstrak daun jeruk nipis Juliana, Intan; Fatmawati, Annisa; Munir, Muhammad Abdurrahman; Emelda, Emelda; Rahmawati, Feti
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.188

Abstract

Moringa leaves are a major source of antioxidant compounds due to their high content in carotenoids, ascorbic acid, glucosinolates and other bioactives. Lime contains elements of useful chemical compounds, such as alkaloids, polysaccharides, flavonoids, and essential oils. This study aims to obtain a gel formula that is physically stable and stable during storage using the Freeze-Thaw Cycling method from Moringa leaf extract and lime leaf extract. This research is a laboratory experimental research. Gel preparation was carried out with varying concentrations of Moringa leaf extract and lime leaf extract F1 (75%:25%), F2 (50%:50%), and F3 (25%:75%). Testing the physical properties of the gel includes organoleptic, pH, homogeneity, viscosity, spreadability, adhesion and syneresis. The stability test carried out was a stability test using the Freeze-Thaw Cycling method for 3 cycles by observing the stability to be carried out where each cycle observed physical changes in the gel including organoleptic, homogeneity and pH. The results of gel preparations of the combination of ethanol extract of moringa leaves and lime leaves of formulations 1, 2, and 3 with differences in the concentration of the active substance were declared stable, because there was no significant change from organoleptic observations, homogeneity, pH, adhesion and spreadability. However, statistical tests stated that the 4℃ temperature adhesion test obtained a p value (<0.05) and a 40℃ temperature p value (>0.05), while the 4℃ and 40℃ temperature spreadability test obtained a p value (<0. 05).
Evaluasi aktivitas analgesik dan antidiare ekstrak etanol bunga telang (Clitoria ternatea Linn.) Ananda, RA Dewinta Sukma; Kusumawardani , Nurul; Fauzi , Rizal; Estiningsih , Daru; Emelda, Emelda; Solikah , Wahyu Yuliana; Nurinda , Eva; Gunawan , Adhi; Ramandani , Wulan; Stiawati , Rika
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.558

Abstract

The analgesic and antidiarrheal effects of Clitoria ternatea Linn. flower extract were tested in mice. A significant analgesic response (p<0.05) was observed in acetic acid-induced pain models in a dose-dependent manner. The percent protection of analgesic properties was calculated from the reduction of writhing by butterfly pea ethanol extract. The Butterfly pea extract doses at 100, 200, and 400 mg/ kg showed analgesic protection by 76.6% (9.4  ± 3.65), 93.9% (2.4 ± 1.95), and 97.5% (1.0 ± 0.71), respectively. The antidiarrheal properties of Clitoria ternatea Linn. flower extract were assessed using the castor oil-induced diarrhea method. Clitoria ternatea Linn. flower extract delayed the onset of castor oil-induced diarrhea in a dose-dependent manner and reduced the frequency of defecation. There was no significant difference (p>0.05) between the effects of 400 mg/kg of Clitoria ternatea Linn. flower extract and loperamide in protecting mice against castor oil-induced diarrhea. Based on the study results, it is suggested that the Clitoria ternatea Linn. flower extract has strong analgesic and antidiarrheal properties. 
Co-Authors Abd. Rasyid Syamsuri Ajat, Ajat Azizah, Abibatul Banafsaj, Zakia Irbah Calista, Avissa Dewi, Alvina Fitriya Didik Yuni Prasetya Dilla, Triani Utami Dwinta, Eliza Eliyanah, Eliyanah Estiningsih , Daru Estiningsih, Daru Fatmawati, Annisa Fauzi , Rizal Fitri, Nurwijaya Gunawan , Adhi Hafid, Pera Yulia Hafid, Perawati Haryanggita, Bariqna'im Katon Heriyani, Yeni Ichwan Ridwan Rais Juliana, Intan Kusumawardani , Nurul Kusumawardani, Nurul Lubis, Abdul Rahman Mardianna, Nova Mindari, Ellisyah Muhammad Abdurrahman Munir Nabila , Lathifa Nofrianto, Robby Norhayatun, Norhayatun Nurhidayanti, Nurhidayanti Nurinda , Eva Octaviani, Ani Pothitirat, Werayut Pratiwi, Dinda Ayu Pratiwi, Sindi Priyanti, Nita Putri Ayu Lestari Putri, Ade Lia Rahmawati, Feti Rahmi, Lisa Amelia Ramadhani, Sunainatul Ramandani , Wulan Rizal Fauzi Robby, Robby Safitri, Eka Asriani Saroya, Nadia Tus Sarwadhamana, Raden Jaka Septariani, Jumania Septiawan, Azizah Nada Solikah , Wahyu Yuliana Solikah, Wahyu Yuliana Sri Watini Stiawati , Rika Sukma Ananda , RA Dewinta Yeni Haryani, Yeni Yeni Heryani Yunitasari, Septiyani Endang