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Journal : Jurnal Ilmiah Medicamento

Survey Penerimaan Konsumen dan Uji Iritasi terhadap Sediaan Gel Masker Peel-Off Batang Pisang (Musa paradisiaca L.) dan Bunga Widuri (Calotropis gigantea L.) Megawati, Fitria; Dewi, Ni Luh Kade Arman Anita; Agustini, Ni Putu Dewi; Suwantara, I Putu Tangkas; Dewi, Ni Made Sintia
Jurnal Ilmiah Medicamento Vol 10 No 1 (2024): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v10i1.5372

Abstract

Peel-off gel masks made from extracts of banana stem (Musa paradisiaca L.) and widuri flower (Calotropis gigantea L.) are natural cosmetic products that contain flavonoids, a secondary metabolite that acts as an antioxidant. The evaluation by consumers is important to understand the level of product acceptance and preference in the market. This study aims to evaluate consumer acceptance of peel-off gel masks made from banana stem and widuri flower extracts, using a quantitative descriptive survey. The sample was collected using an accidental sampling technique from panelists aged between 20 and 40 years old at Universitas Mahasaraswati Denpasar. The survey was conducted through a Google Form that contained questions about consumer preferences (hedonic test) for aroma, viscosity, texture, color, stickiness, and overall product. A total of 40 panelists participated in the hedonic test, while the irritation test was conducted on 9 panelists to observe the possibility of redness or itching reactions on the skin after use. The banana stems peel-off gel mask scored 21.1 in the hedonic test, while the widuri flower peel-off gel mask scored 20.3. The results indicate that the banana stem peel-off gel mask was accepted by 84.4% of the participants in the hedonic test, while the widuri flower peel-off gel mask was accepted by 81.5% of the participants. The irritation test results indicate that neither type of peel-off gel mask caused any irritation after use. Panelists preferred the banana stem peel-off gel mask over the widuri flower peel-off gel mask, with a score of 21.1 and a percentage of 84.4%. Both types of peel-off gel masks are safe to use.
Karagenan Rumput Laut Merah Bali (Gracilaria sp.) sebagai Antibakteri terhadap Delapan Bakteri Patogen Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Dewi, Ni Luh Kade Arman Anita; Yuda, Putu Era Sandhi Kusuma; Wardani, I Gusti Agung Ayu Kusuma; Juliadi, Debby; Putri, Ni Kadek Dila Pratiwi; Putri, Ni Kadek Nisa Leoni; Darmawan, I Wayan Agus; Yanti, Ni Kadek Pradnya
Jurnal Ilmiah Medicamento Vol 11 No 1 (2025): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i1.10349

Abstract

The increase in infection cases every year, coupled with the rise in resistance cases, increases the urgency of exploring antimicrobial agents. Gracilaria sp. is a red seaweed that is widely known as one of the potential producers of active metabolites, sulfated polysaccharides. Carrageenan is one form of sulfated polysaccharide that has antimicrobial activity. This study was conducted to evaluate the antibacterial activity of carrageenan derived from Gracilaria sp. against several pathogenic bacteria, including Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, Streptococcus pyogenes, and Salmonella typhi. Carrageenan was extracted from Gracilaria sp. samples obtained from the South Denpasar area (Bali) using KOH. An antibacterial activity assay of carrageenan was carried out using an agar well diffusion method with nutrient agar media. Tests were conducted at concentrations of 1 and 5 mg/mL (E. coli and S. epidermidis), 20, 30, 40 mg/mL (S. aureus, S. pyrogenes, E. faecalis, and S. typhi), 50, 75, and 100 mg/mL (P. aeruginosa and K. pneumoniae). Incubation was carried out for 24 hours at ± 37 °C. Data were analyzed statistically by one-way ANOVA and Kruskal-Wallis with a 95% confidence level. The results showed that carrageenan extracted from Gracilaria sp. exhibited significant antibacterial activity against several pathogenic bacteria, especially gram-negative bacteria. The antibacterial activity produced in this study was proportional to the increase in concentration, where the inhibitory activity produced increased as the concentration of carrageenan increased. It can be concluded that carrageenan has the potential to be an antibacterial.