Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Usadha

Uji Aktivitas Antibakteri Rebusan dan Infusa Daun Jeruju (Achantus illicifolious) terhadap Bakteri Methicilin Resistant Staphylococcus aureus (MRSA) Maria Dewi, Ni Putu; Cahyaningsih, Erna; Arman Anita Dewi, Ni Luh Kade; Surya Rahadi, I Wayan; Sandhi Kusuma Yuda, Putu Era; Santoso, Puguh
Usadha Vol 3 No 1 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i1.7222

Abstract

Infectious diseases are still a health problem throughout the world, including in Indonesia. One cause of infection that needs to be watched out for is resistance to Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria. Continuous use of antibiotics can cause problems with microbial resistance. Indonesia has various plant species that can actually provide benefits but have not been specifically cultivated. Jeruju leaves (Achanthus ilicifolius) from mangrove plants contain bioactive compounds that have the potential to be antibacterial. The aim of this research is to determine the antibacterial activity of Jeruju leaf decoction and infusion against MRSA bacteria. Antibacterial activity testing uses MRSA bacteria. The results of the phytochemical screening of Jeruju leaf infusion contained secondary metabolite compounds in the form of flavonoids, tannins, saponins and quinones. Meanwhile, the results of the phytochemical screening of Jeruju leaf decoction contained secondary metabolites in the form of tannins, saponins and quinones. Based on the results of research conducted on infusions and decoctions of Jeruju leaves at concentrations of 30%, 60% and 90%, they did not have inhibitory power on the antibacterial activity of MRSA, as seen from the inhibition zone. Zero inhibition zone for MRSA bacteria. It can be concluded that the infusion and decoction of Jeruju (Achantus illicifolious) leaves do not have antibacterial activity against MRSA.
Identifikasi Senyawa Fitokimia dan Uji Aktivitas Antioksidan pada Cascara (Coffea arabica L.) Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Yuda, Putu Era Sandhi Kusuma; Handani, Dewa Ayu Sri; Dewi, Ni Luh Kade Arman Anita; Megawati, Fitria; Tirtayasa, Gede Agus Ari
Usadha Vol 4 No 1 (2025): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v4i1.12181

Abstract

Cascara refers to the dried husk of coffee cherries. It has garnered significant attention in recent research due to its phytochemical composition and potential health benefits. Several studies have highlighted the presence of bioactive compounds and the antioxidant activity exhibited by cascara. This study aims to investigate the phytochemical content and antioxidant potential of cascara. The cascara was extracted using the maceration method with 96% ethanol, followed by phytochemical screening for alkaloids, flavonoids, tannins, saponins, terpenoids, steroids, and quinones using standard color reactions in test tubes. Antioxidant activity was assessed via the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay, with ascorbic acid as a reference compound. The phytochemical profile of the extract was identified using gas chromatography-mass spectrometry (GC-MS). The findings indicated that cascara contains alkaloids, flavonoids, tannins, saponins, and triterpenoids. GC-MS analysis identified caffeine, hexadecanoic acid (methyl ester), and hexadecanoic acid (ethyl ester) as the predominant compounds in cascara. The antioxidant activity test using the DPPH method demonstrated that the ethanol extract of cascara possesses moderate antioxidant potential, with an average IC50 value of 108.49 ± 1.28 ppm. Ascorbic acid, the reference compound used in this study, yielded an IC50 of 2.53 ppm, categorized as very strong. This research underscores cascara’s potential as a valuable source of antioxidants with significant health benefits, influenced by geographic factors affecting its bioactive compound profile. Consequently, cascara holds promise for further development as a raw material for functional health-promoting products.
Review: Pemanfaatan Tanaman sebagai Fitoterapi pada Diabetes Mellitus Dewi, Ni Luh Kade Arman Anita; Prameswari, Putu Nimas Diyah; Cahyaningsih, Erna; Megawati, Fitria; Agustini, Ni Putu Dewi; Juliadi, Debby
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5562

Abstract

Diabetes is a chronic disease that occurs due to high levels of sugar in the blood, this can occur when the pancreas does not produce enough insulin (a hormone that regulates blood sugar or glucose), or when the body cannot effectively use the insulin it produces. Management of DM patients can be carried out with non-pharmacological and pharmacological therapies. The method used in the journal review was to search for the keyword "diabetes mellitus herbal medicine" for clinical studies on plant-derived products for the treatment of diabetes mellitus. Search terms included “phytotherapy”, “phytochemicals”, “medicinal plant products”, “herbal medicine”, and “diabetes mellitus”. Involving plant-derived compounds and pigmentation as outcome measures were included. In this review article, 30 journals were collected from which the objectives and results of the research in the journal were obtained. The goal is as an alternative management treatment to control blood sugar levels. For some of the compounds we discuss, among others: Flavonoids, Allicin, Lectins, Alkaloids, Andrographolid, Curcumin, Cinnamaldehyde, peptides, Phenolics, Tannins.
Kajian Etnofarmasi Kelompok Masyarakat Banjar Kepisah Sumerta Kelod Denpasar Dewi, Ni Luh Kade Arman Anita; Adi Lestari, Ni Putu Wisnu; Suradnyana, I Gede
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7390

Abstract

Ethnopharmacy is a part of pharmaceutical science that includes understanding medicinal plants used and studying how certain ethnic or community communities use drugs. Studies on ethnopharmaceuticals have never been carried out on the community in the Sumerta Kelod area, especially the Banjar Keseparat community. Where there are still many Banjar Keseparat people who use plants as medicine. This research is a descriptive research. Data collection was done by interview method. The sampling technique in this study used a non-probability sampling method. The results showed that ethnopharmaceutical research that had been carried out in Banjar Kejuangan, Sumerta Kelod obtained in general 12 types of plants that were located in Banjar Kejuangan, Sumerta Kelod. Where the plant parts used were 67% leaves, 17% rhizomes, 8% stems, and 8% flowers. The method of processing plants with the highest frequency was by boiling, which was 92%. The most frequently used method of using ethnopharmaceutical plants is by drinking, which is equal to 83%, and the most frequently used indication for medicinal plants is to treat joint problems, such as muscle pain and gout (28%).