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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) HIGEIA (Journal of Public Health Research and Development) Majalah Farmasetika Afiasi : Jurnal Kesehatan Masyarakat Jurnal Farmasi Binawan Student Journal Jurnal Progress Administrasi Publik (JPAP) Berita Kedokteran Masyarakat Journal Microbiology Science Journal of Indonesian Health Policy and Administration Jurnal Pengabdian Masyarakat Inovatif Jurnal Pengabdian Masyarakat Inovatif Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Hermawati, Ema
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Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Analisis Kuantitatif Flavonoid Total dalam Ekstrak Daun Bidara (Ziziphus mauritiana) sebagai Dasar Pengembangan Produk Farmasi Alami: Quantitative Analysis of Total Flavonoids in Bidara (Ziziphus mauritiana) Leaf Extract as a Basis for Natural Pharmaceutical Product Development Christian, Yulius Evan; Chandra, Pra Panca Bayu; Hermawati, Ema; Ismyama, Dian Farida
Binawan Student Journal Vol. 7 No. 2 (2025)
Publisher : Direktorat Penelitian, Pengabdian Masyarakat, Dan Kerjasama Universitas Binawan (DPPMK Universitas Binawan)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54771/v2zj1q78

Abstract

Bidara leaves (Ziziphus mauritiana) are a herbal plant that is known to be rich in bioactive compounds, especially flavonoids, which have antioxidant, anti-inflammatory and antimicrobial activities. This study aims to determine the total flavonoid content in bidara leaf extract and evaluate the potential of its secondary metabolites for pharmaceutical and cosmetic applications. Phytochemical screening was carried out to identify secondary metabolite content, which included flavonoids, alkaloids, saponins, tannins and phenolics. Extraction was carried out using the maceration method with 96% ethanol solvent, followed by filtering and evaporation of the solvent using a rotary vacuum evaporator at a temperature of 40°C to produce a thick extract. Determination of total flavonoid levels was carried out using the UV-Vis spectrophotometric method with aluminum chloride reagent at a wavelength of 441 nm, using quercetin as a standard. The results showed that the total flavonoid content in bidara leaf extract reached 3202.43 mg QE/100 g dry extract. This high flavonoid content supports antioxidant activity through the mechanism of capturing free radicals, chelating transition metal ions, and inhibiting lipid peroxidation. In addition, the flavonoids in the extract have the potential to be anti-inflammatory by inhibiting pro-inflammatory enzymes and modulating cytokines, as well as antimicrobial through disrupting microbial membranes. The conclusion of this research is that bidara leaf extract has great potential to be developed as an active ingredient in pharmaceutical and cosmetic formulations.
ANALISIS PENGELOLAAN ASET DALAM MENDUKUNG OPERASIONAL PELAYANAN DI MAL PELAYANAN PUBLIK KOTA CIMAHI Hermawati, Ema; Afandi, Muhamad Nur; Yustiono, Eris; Kurniawan, Iwan
Jurnal Progress Administrasi Publik Vol. 5 No. 2 (2025): Jurnal Progress Administrasi Publik (JPAP)
Publisher : Program Studi Administrasi Publik, FISIP, Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/61bet020

Abstract

Asset management is one of the important aspects in supporting the operational services at the Public Service Mall (MPP) of Cimahi City as a center for integrated services for the community. This research aims to analyze asset management at the MPP of Cimahi City. The research method used is descriptive qualitative with data collection techniques through interviews, observations, and documentation studies. The analysis is conducted using the asset management theory approach according to Siregar which includes five indicators: asset inventory, legal audit, asset valuation, asset optimization, and supervision and control. The results of the study indicate that asset management at the MPP of Cimahi City is already functioning quite well. However, several constraints were found, namely the presence of assets in several tenants that do not have asset inventory labeling, in addition, the inventory data regarding asset damage and loss is still minimal, and there are assets that have not been optimally utilized. The conclusion of this study is that asset management in the MPP of Cimahi City has generally supported operational services, but there are still constraints in the aspects of asset inventory and asset optimization. To address this, a digital reporting system is needed to record asset damage or loss in real time. Additionally, it is necessary to prepare clear and structured Standard Operating Procedures (SOP) regarding the management of regional-owned goods. The next effort involves socialization and education for tenant officers and related parties involved in asset management, including technical training in the operation of certain assets.   Keywords: Asset Management; Public Service Mall; Service Operation
Faktor Organisasi dengan Kinerja Penyuluh Keluarga Berencana di Kabupaten Jember Arta, Magdalena Yuni; Hermawati, Ema; Sandra, Christyana; Witcahyo, Eri
Afiasi : Jurnal Kesehatan Masyarakat Vol. 10 No. 3 (2025): Afiasi
Publisher : Universitas Wiralodra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31943/afiasi.v10i3.543

Abstract

The coverage of active KB participants has a target based on the Estimated Community Demand (PPM), so each year it is expected that the achievements will meet or exceed the target. The problem lies in the significant disparity in the coverage rates of new family planning participants, based on the 2023 data on the achievements of new participants from government and private sectors, the districts with the lowest achievements of new KB participants were Patrang (7.22%), Sukorambi (8.41%), Balung (9.98%), Arjasa (12.87%), Mayang (20.20%), Jelbuk (27.87%), Silo (28.87%), and Umbul Sari District (29.58%). The districts with the highest achievements were Sukowono (719.27%), Wuluhan (694.80%), Tempurejo (644.23%), and Rambipuji (596.35%). The purpose of this study was to analyze organizational factors associated with the performance of KB Counselor. This study employed a quantitative approach with a cross-sectional design. The independent variables were age, years of service, perception of rewards, work motivation, and leadership, while the dependent variable was the performance of KB Counselor. Data analysis included univariate, bivariate, and multivariate analyses using logistic regression. The results showed that there was a significant relationship between work motivation (p-value = 0.045) and leadership (p-value = 0.000) with the performance of KB Counselor, while no significant relationship was found between age (p-value = 0.405), years of service (p-value = 0.513), and perception of rewards (p-value = 1.000) with performance. The most dominant variable associated with KB Counselor performance was leadership, with an OR = 11.2 (95% CI = 2.2–56.2).
Evaluasi Aktivitas Antiinflamasi Nanoemulsi Teripang (Stichopus variegatus) Secara In Vitro dengan Metode Denaturasi Bovine Serum Albumin Hermawati, Ema; Ismyama, Dian Farida; Christian, Yulius Evan; Chandra, Pra Panca Bayu
Majalah Farmasetika Vol 11, No 2 (2026)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v11i2.69257

Abstract

Teripang atau dikenal juga dengan sebutan gamat (Stichopus variegatus) merupakan bahan alam kelautan yang banyak dimanfaatkan di berbagai negara Asia, termasuk Indonesia. Teripang berpotensi dikembangkan di bidang obat maupun bidang kosmetik, karena mengandung berbagai macam bioaktif.  Salah satu kandungan teripang adalah saponin yang berpotensi memiliki aktivitas sebagai antiinflamasi dan aktibakteri. Tantangan dari pembuatan produk kosmetik yang terbuat dari bahan aktif bahan alam adalah stabilitas dan penetrasi bahan aktif ke dalam kulit. Teknologi nanopartikel digunakan untuk meningkatkan stabilitas dan bioavabilitas bahan aktif. Ekstrak teripang diperoleh melalui metode maserasi dengan rendemen 5,3%. Kadar saponin pada ekstrak teripang yang ditetapkan secara kuantitatif menggunakan spektrofotometer UV-Vis menunjukkan kadar sebesar 6,14 mg/g sampel. Nanoemulsi ekstrak teripang diformulasikan menggunakan metode gelasi ionik dengan kitosan sebagai polimer pembentuk. Hasil karakterisasi menunjukkan ukuran partikel rata-rata 733,7 nm, polydispersity index (PDI) 0,584, serta zeta potensial +29,14 mV, yang mengindikasikan stabilitas koloid yang baik. Aktivitas antiinflamasi diuji menggunakan metode denaturasi Bovine Serum Albumin (BSA) dan diperoleh nilai IC₅₀ sebesar 144,34 bpj, yang menunjukkan kemampuan penghambatan denaturasi protein.
Co-Authors . Syamsudin Achmad Rizki Azhari Afandi, Muhamad Nur Agustin Kusumayati Ahmad Subagiyo Arta, Magdalena Yuni Bayu Chandra, Pra Panca Budi Hartono Budi Haryanto Chandra, Pra Panca Bayu Christyana Sandra Emilia Pandin Madao Eri Witcahyo Fitria Dewi Sulistiyono Ike Yulia Wiendarlina Irawati, Septiria Ismyama, Dian Farida Iwan Kurniawan Mahyuni, Siti Makful, Martya Rahmaniati Marybet Tri Retno Handayani Novi Fajar Utami Oom Komala Putri, Nur A’isyah Amalia RAHMAT, DENI Resosoedarmo, Budy Rikkit T, Ardy Tanfil Tan, Ardy Tanfil Tanfil T, Ardy Utami, Sri Tjahjani Budi Yulianita Yulius Evan Christian Yustiono, Eris Yustiono