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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) HIGEIA (Journal of Public Health Research and Development) Majalah Farmasetika Afiasi : Jurnal Kesehatan Masyarakat Indonesian Journal of Global Health research Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Farmasi Binawan Student Journal Jurnal Progress Administrasi Publik (JPAP) Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Berita Kedokteran Masyarakat Journal Microbiology Science Journal of Indonesian Health Policy and Administration Pharmacon: Jurnal Farmasi Indonesia Jurnal Pengabdian Masyarakat Inovatif Jurnal Pengabdian Masyarakat Inovatif Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Hermawati, Ema
Unknown Affiliation
Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Effect of Ambient Particulate Matter 2.5 Micrometer (PM2.5) to Prevalence of Impaired Lung Function and Asthma in Tangerang and Makassar Haryanto, Budi; Resosoedarmo, Budy; Utami, Sri Tjahjani Budi; Hartono, Budi; Hermawati, Ema
Kesmas Vol. 10, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Emisi partikel debu 2,5 mikrometer (PM2.5) meningkat dengan bertambahnya jumlah penduduk kota akibat peningkatan angka kendaraan bermotor sebagai transportasi penduduk sehari-hari. Penelitian ini bertujuan untuk mengetahui tingkat gangguan fungsi paru dan asma serta hubungannya dengan kadar ambien PM2.5 pada masyarakat migran di Tangerang dan Makassar dan kondisi sosial ekonomi. Desain potong lintang digunakan dengan melibatkan 4.250 dan 2.900 responden di Tangerang dan Makassar pada bulan April sampai September 2010. Pendekatan cluster sampling diterapkan. Pengukuran ambien PM2.5 di masing-masing kota berdasarkan koordinat 40 lokasi Global Positioning System (GPS). Kadar PM2.5 ditemukan lebih tinggi pada pagi hari dibandingkan siang hari di kedua kota tersebut dengan rata-rata enam kali lipat dari pedoman World Health Organization (WHO) 35 mg/m3. Prevalensi asma ditemukan sama pada kedua kota (1,3%) dan prevalensi gangguan fungsi paru di Makassar lebih tinggi (24%) dibandingkan di Tangerang (21%). Data menunjukkan bahwa tidak terdapat hubungan antara kadar PM2.5 terhadap prevalensi asma dan gangguan fungsi paru di kedua kota. Penelitian ini menguatkan bahwa pajanan PM2.5 berkaitan dengan prevalensi asma dan gangguan fungsi paru serta bukti yang diberikan menunjukkan bahwa efek polusi udara diubah oleh karakteristik lingkungan tertentu. Temuan ini menyarankan adanya perbaikan ventilasi rumah dan ruang tamu yang lebih luas untuk sirkulasi oksigen yang lebih baik. Particulate matter 2.5 micrometer (PM2.5) emission increased with increasing number of urban population as a result of increasing number of motor vehicles for their daily transportation. This study aimed to determine the level of impaired lung function and asthma and its relation to ambient levels of PM2.5 among migrant communities in Tangerang and Makassar and socioeconomic conditions. A cross-sectional design was implemented by involving 4,250 and 2,900 respondents in Tangerang and Makassar respectively on April to September 2010. Cluster sampling approach was applied. PM2.5 ambient measurements in each city were based on the coordinates of 40 global positioning system locations. The PM2.5 levels found higher in the morning than afternoon in both cities, with average about six folds of WHO guideline of 35 mg/m3. Asthma prevalence was found similar in both cities (1.3%) and impaired lung function prevalence in Makassar was higher (24%) than Tangerang (21%). Data showed there was no association between PM2.5 levels to the prevalence of asthma and impaired lung function in both cities. The study confirmed that exposure to PM2.5 is associated with prevalence of asthma and impaired lung function and provided evidence showed that the effect of air pollution was modified by certain living environment characteristics. These findings suggest the improvement of housing ventilations and larger space of living room for better oxygen circulation.
Evaluating spatial analysis of tuberculosis prevalence to identify priority districts or municipalities that need policy attention in West Java Emilia Pandin Madao; Hermawati, Ema; Putri, Nur A’isyah Amalia; Makful, Martya Rahmaniati
BKM Public Health and Community Medicine Vol 40 No 04 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.v40i04.12160

Abstract

Purpose: This study assesses the spatial autocorrelation of tuberculosis (TB) with population density, poverty, personal hygiene and environmental sani- tation (perilaku hidup bersih sehat, PHBS), and housing quality to identify critical areas for targeted TB management in West Java. Methods: This ecological study analyzes secondary data from all TB patients across 27 regencies/cities in West Java Province for 2022. Spatial patterns were examined using the Global Moran's Index and Local Indicators of Spatial Association (LISA). Results: The analysis revealed significant clustering of TB prevalence with population density (p-value = 0.001) and PHBS (p-value = 0.047). At the same time, dispersion was noted with poverty (p-value = 0.355) and a non-significant clustering with housing quality (p-value = 0.270). Notably, ten regencies/cities exhibited significant local spatial autocorrelat- ion, indicating priority areas for intervention. Conclusion: TB prevalence in West Java show a positive spatial correlation with population density and PHBS, indicating clustered patterns that necessitate focused policy attention. The absence of a spatial correlation between poverty and housing quality suggests different intervention strategies may be required. TB intervention should be prioritized in areas like Bekasi Regency, Bekasi City, Bogor Regency, Bogor City, Cianjur Regency, and Depok City, where TB prevalence is significantly associated with key spatial factors.
MAP of Tuberculosis Incidence in West Java Province in 2023 Wulandini, Fondariesta; Hermawati, Ema; Wulandari, Melly
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6140

Abstract

Indonesia has various infectious diseases, one of which is tuberculosis. This disease is caused by a pathogenic agent, namely the bacteria Mycobacterium tuberculosis, which can cause primary symptoms such as a continuous cough. West Java Province is ranked first in the most TB cases in Indonesia, with a total of 203,226 cases in 2023. This study aims to map the spread of the disease by describing the distribution of tuberculosis cases and mapping the level of vulnerability through tuberculosis risk factors. The method used is a descriptive research on the Geographic Information System (GIS) approach with scoring techniques. The data used is in the form of secondary data from the official website (open data access) of the Central Statistics Agency (BPS) of West Java Province. After the collection of variable data from BPS, it is then analyzed with shapefile spatial data through the QGIS program software. The results of this study show that of the 27 districts/cities in West Java Province, there are 2 areas, namely Bogor Regency and Bekasi City, which have a very high level of vulnerability. This vulnerability overview is expected to be the government's initial step in efforts to control and prevent tuberculosis incidents through case detection, strengthening TB prevention programs and establishing cross-sectoral cooperation related to TB incidence, especially in high-risk areas.
Analisis Kuantitatif Flavonoid Total dalam Ekstrak Daun Bidara (Ziziphus mauritiana) sebagai Dasar Pengembangan Produk Farmasi Alami: Quantitative Analysis of Total Flavonoids in Bidara (Ziziphus mauritiana) Leaf Extract as a Basis for Natural Pharmaceutical Product Development Christian, Yulius Evan; Chandra, Pra Panca Bayu; Hermawati, Ema; Ismyama, Dian Farida
Binawan Student Journal Vol. 7 No. 2 (2025)
Publisher : Direktorat Penelitian, Pengabdian Masyarakat, Dan Kerjasama Universitas Binawan (DPPMK Universitas Binawan)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54771/v2zj1q78

Abstract

Bidara leaves (Ziziphus mauritiana) are a herbal plant that is known to be rich in bioactive compounds, especially flavonoids, which have antioxidant, anti-inflammatory and antimicrobial activities. This study aims to determine the total flavonoid content in bidara leaf extract and evaluate the potential of its secondary metabolites for pharmaceutical and cosmetic applications. Phytochemical screening was carried out to identify secondary metabolite content, which included flavonoids, alkaloids, saponins, tannins and phenolics. Extraction was carried out using the maceration method with 96% ethanol solvent, followed by filtering and evaporation of the solvent using a rotary vacuum evaporator at a temperature of 40°C to produce a thick extract. Determination of total flavonoid levels was carried out using the UV-Vis spectrophotometric method with aluminum chloride reagent at a wavelength of 441 nm, using quercetin as a standard. The results showed that the total flavonoid content in bidara leaf extract reached 3202.43 mg QE/100 g dry extract. This high flavonoid content supports antioxidant activity through the mechanism of capturing free radicals, chelating transition metal ions, and inhibiting lipid peroxidation. In addition, the flavonoids in the extract have the potential to be anti-inflammatory by inhibiting pro-inflammatory enzymes and modulating cytokines, as well as antimicrobial through disrupting microbial membranes. The conclusion of this research is that bidara leaf extract has great potential to be developed as an active ingredient in pharmaceutical and cosmetic formulations.
ANALISIS PENGELOLAAN ASET DALAM MENDUKUNG OPERASIONAL PELAYANAN DI MAL PELAYANAN PUBLIK KOTA CIMAHI Hermawati, Ema; Afandi, Muhamad Nur; Yustiono, Eris; Kurniawan, Iwan
Jurnal Progress Administrasi Publik Vol. 5 No. 2 (2025): Jurnal Progress Administrasi Publik (JPAP)
Publisher : Program Studi Administrasi Publik, FISIP, Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/61bet020

Abstract

Asset management is one of the important aspects in supporting the operational services at the Public Service Mall (MPP) of Cimahi City as a center for integrated services for the community. This research aims to analyze asset management at the MPP of Cimahi City. The research method used is descriptive qualitative with data collection techniques through interviews, observations, and documentation studies. The analysis is conducted using the asset management theory approach according to Siregar which includes five indicators: asset inventory, legal audit, asset valuation, asset optimization, and supervision and control. The results of the study indicate that asset management at the MPP of Cimahi City is already functioning quite well. However, several constraints were found, namely the presence of assets in several tenants that do not have asset inventory labeling, in addition, the inventory data regarding asset damage and loss is still minimal, and there are assets that have not been optimally utilized. The conclusion of this study is that asset management in the MPP of Cimahi City has generally supported operational services, but there are still constraints in the aspects of asset inventory and asset optimization. To address this, a digital reporting system is needed to record asset damage or loss in real time. Additionally, it is necessary to prepare clear and structured Standard Operating Procedures (SOP) regarding the management of regional-owned goods. The next effort involves socialization and education for tenant officers and related parties involved in asset management, including technical training in the operation of certain assets.   Keywords: Asset Management; Public Service Mall; Service Operation
Faktor Organisasi dengan Kinerja Penyuluh Keluarga Berencana di Kabupaten Jember Arta, Magdalena Yuni; Hermawati, Ema; Sandra, Christyana; Witcahyo, Eri
Afiasi : Jurnal Kesehatan Masyarakat Vol. 10 No. 3 (2025): Afiasi
Publisher : Universitas Wiralodra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31943/afiasi.v10i3.543

Abstract

The coverage of active KB participants has a target based on the Estimated Community Demand (PPM), so each year it is expected that the achievements will meet or exceed the target. The problem lies in the significant disparity in the coverage rates of new family planning participants, based on the 2023 data on the achievements of new participants from government and private sectors, the districts with the lowest achievements of new KB participants were Patrang (7.22%), Sukorambi (8.41%), Balung (9.98%), Arjasa (12.87%), Mayang (20.20%), Jelbuk (27.87%), Silo (28.87%), and Umbul Sari District (29.58%). The districts with the highest achievements were Sukowono (719.27%), Wuluhan (694.80%), Tempurejo (644.23%), and Rambipuji (596.35%). The purpose of this study was to analyze organizational factors associated with the performance of KB Counselor. This study employed a quantitative approach with a cross-sectional design. The independent variables were age, years of service, perception of rewards, work motivation, and leadership, while the dependent variable was the performance of KB Counselor. Data analysis included univariate, bivariate, and multivariate analyses using logistic regression. The results showed that there was a significant relationship between work motivation (p-value = 0.045) and leadership (p-value = 0.000) with the performance of KB Counselor, while no significant relationship was found between age (p-value = 0.405), years of service (p-value = 0.513), and perception of rewards (p-value = 1.000) with performance. The most dominant variable associated with KB Counselor performance was leadership, with an OR = 11.2 (95% CI = 2.2–56.2).
Quality Evaluation and Phytochemical Screening of Kaempferia galanga and Zingiber zerumbet Rhizome Extracts Christian, Yulius Evan; Hermawati, Ema; Qodriah, Rahmatul; Efrilia, Mega; Falestin, Senny Listy Kartika; Chandra, Pra Panca Bayu; Whardhani, Sabrina K.
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.651

Abstract

Indonesia has rich biodiversity that provides potential sources of traditional medicine, including Kaempferia galanga and Zingiber zerumbet rhizomes, which are widely used in ethnomedicine. This study aimed to evaluate the quality parameters and phytochemical constituents of both rhizomes in accordance with pharmacopoeial standards. The research involved simplicia preparation, extraction using 96% ethanol by maceration, and subsequent quality testing, including specific, non-specific, and phytochemical screening. Macroscopic and microscopic examinations confirmed the authenticity of the rhizomes, and purity tests showed that foreign organic matter levels were within the acceptable limits (≤2%). The extractive values demonstrated that K. galanga had a higher water-soluble content, whereas the two species had comparable ethanol fractions. Specific and non-specific quality parameters were quantitatively determined in compliance with the Indonesian Herbal Pharmacopoeia. The water-soluble extractive value was 11.30% for K. galanga and 9.20% for Z. zerumbet, while ethanol-soluble extractive values were both 5.30%. Loss on drying and moisture content remained below 10% for both rhizomes, meeting the required threshold. Specific gravity values of 0.8367 g/mL (K. galanga) and 0.79 g/mL (Z. zerumbet) indicated proper extract concentration. These parameters confirm the extracts' quality, stability, and suitability for further phytopharmaceutical development.
Evaluasi Aktivitas Antiinflamasi Nanoemulsi Teripang (Stichopus variegatus) Secara In Vitro dengan Metode Denaturasi Bovine Serum Albumin Hermawati, Ema; Ismyama, Dian Farida; Christian, Yulius Evan; Chandra, Pra Panca Bayu
Majalah Farmasetika Vol. 11 No. 2, Tahun 2026 (In Press)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v11i2.69257

Abstract

Teripang atau dikenal juga dengan sebutan gamat (Stichopus variegatus) merupakan bahan alam kelautan yang banyak dimanfaatkan di berbagai negara Asia, termasuk Indonesia. Teripang berpotensi dikembangkan di bidang obat maupun bidang kosmetik, karena mengandung berbagai macam bioaktif.  Salah satu kandungan teripang adalah saponin yang berpotensi memiliki aktivitas sebagai antiinflamasi dan aktibakteri. Tantangan dari pembuatan produk kosmetik yang terbuat dari bahan aktif bahan alam adalah stabilitas dan penetrasi bahan aktif ke dalam kulit. Teknologi nanopartikel digunakan untuk meningkatkan stabilitas dan bioavabilitas bahan aktif. Ekstrak teripang diperoleh melalui metode maserasi dengan rendemen 5,3%. Kadar saponin pada ekstrak teripang yang ditetapkan secara kuantitatif menggunakan spektrofotometer UV-Vis menunjukkan kadar sebesar 6,14 mg/g sampel. Nanoemulsi ekstrak teripang diformulasikan menggunakan metode gelasi ionik dengan kitosan sebagai polimer pembentuk. Hasil karakterisasi menunjukkan ukuran partikel rata-rata 733,7 nm, polydispersity index (PDI) 0,584, serta zeta potensial +29,14 mV, yang mengindikasikan stabilitas koloid yang baik. Aktivitas antiinflamasi diuji menggunakan metode denaturasi Bovine Serum Albumin (BSA) dan diperoleh nilai IC₅₀ sebesar 144,34 bpj, yang menunjukkan kemampuan penghambatan denaturasi protein.
Co-Authors . Syamsudin Achmad Rizki Azhari Afandi, Muhamad Nur Agustin Kusumayati Ahmad Subagiyo Andarini, Sari Yuli Arta, Magdalena Yuni Bayu Chandra, Pra Panca Budi Hartono Budi Haryanto Chandra, Pra Panca Bayu Christyana Sandra Efrilia, Mega Emilia Pandin Madao Eri Witcahyo Falestin, Senny Listy Kartika Fitria Dewi Sulistiyono Handayani, Marybet Tri Retno Hayuni, Julia Putri Ike Yulia Wiendarlina Irawati, Septiria Ismyama, Dian Farida Iwan Kurniawan Laila Fitria M. Romli Mahyuni, Siti Makful, Martya Rahmaniati Novi Fajar Utami Oom Komala Putri, Nur A’isyah Amalia Qodriah, Rahmatul RAHMAT, DENI Resosoedarmo, Budy Rikkit Sifa Fauzia, Sifa T, Ardy Tanfil Tan, Ardy Tanfil Tanfil T, Ardy Tri Retno Handayani, Marybet Utami, Sri Tjahjani Budi Whardhani, Sabrina K. Wulandari, Melly Wulandini, Fondariesta Yulianita Yulius Evan Christian Yustiono, Eris Yustiono Zakianis Zakianis