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Evy Diah Woelansari
Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Surabaya Surabaya
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY

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Validation of Rapid Antibody (IgM – IgG) Test Kit for SARS-CoV-2 Infection in Surabaya, Indonesia Museyaroh Museyaroh; Puspa Wardani; Aryati Aryati; Evy Diah Woelansari
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 4 No 2 (2022): Enhanced knowledge of laboratory medicine's role in healthcare
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v4i2.3027

Abstract

At the beginning of the Corona Virus Disease 2019 (COVID-19) pandemic, rapid test examinations were widely used as a screening for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. The purpose of this examination was to detect SARS-CoV-2 IgM/IgG antibodies in the patient's body. One of these tests uses the immunochromatographic method. This study aims to determine the validity of immunochromatography. The study was conducted from August to September 2020. The sample used in this study was 100 patients. The research was conducted at Husada Utama Hospital Surabaya, Indonesia. According to the study's findings, the Zybio brand reagent kit has an accuracy of 85%, a sensitivity of 82%, a specificity of 88%, a positive predictive value of 87%, and a negative predictive value of 83%. In the group of patients who experienced clinical symptoms, < 7 had a sensitivity of 50%, specificity of 88%, positive predictive value of 60%, negative predictive value of 83%, and accuracy of 77.94% while the group of patients experiencing clinical symptoms > 7 days, had a sensitivity value of 100 %, specificity of 88%, positive predictive value of 84%, negative predictive value of 100%, and accuracy of 92.68%. Based on these results, the conclusion is that the Zybio brand reagent kit has a relatively high sensitivity, specificity, positive predictive value, negative value, and sample accuracy. In the group with clinical sensitivity < 7 days, the positive predictive value and accuracy are lower than the sample group with clinical symptoms > 7 days but have the same specificity.
Co-Authors , Suhariyadi ., Pestariati A.A. Ketut Agung Cahyawan W Abror, Yogi Khoirul Adelia Gita Prasasti Alifiah, Salsabiil Rochman Aliya Ayu Rizqiyah Anggraini, Anita Dwi Anita Dwi Anggraini Aprilyadi, Nadi Arifin, Syamsul Diah Arta, Shela Yuni Aryati Aryati Ayu Puspitasari, Ayu Cheppy Juwita Ayuningrum Christ Kartika Rahayuningsih Christiyaningsih, Juliana Diah Titik Mutiarawati Edy Haryanto Eka Safitri, Devayanti Endarini, Lully Hanni Entuy Kurniawan Kurniawan Evi Yunita Nugrahini Fadia Rakhmalia Fortuna Aliza Dewi Ginarsih, Yuni Handayati, Anik Hariyanto Hariyanto Hermiyanti, Pratiwi Ira Puspita Sari Ira Rahayu Tiyar Istanto, Wisnu Istiqomah Istiqomah istiqomah istiqomah Juliana Christyaningsih Kasiati Kiaonarni O.W Krihariyani, Dwi Kumahartati, Intan Lembunai Tat Alberta Liliek Soetjiatie Lully Hani Endarini Luthfi Rusyadi Mamik Mamik Mamik Mamik Minarti Minarti Minarti Minarti Mohd Nazil Salleh Mujayanto Museyaroh, Museyaroh Mutiarawati, Diah Titik Nabilah, Musholli Himmatun Niswata, Navila Arfianti Novikasari, Caturizkyana Nur Hatijah Nurwening TW P, Teresia Retna Pertiwi, Resty Cahya Prasasti, Adelia Gita Purnomowati, Anik Purwati Purwati Puspa Wardani Rahayu Sumaningsih Rahayuningsih, Christ Kartika Rahayuningsih, Christ. Kartika Rahma Yuliana, Putri Ramadhany, Rieke Dwi Retno Sasongkowati Retno Sasongkowati Retno Sasongkowati Rieke Dwi Ramadhany Riyanto, Digdo Rizqiyah, Aliya Ayu Salsabiil Rochman Alifiah Sasongkowati, Retno Sri Sulami Endah Astuti Sri Utami Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suhariyadi Suliati Suliati Suliati Suliati Suliati Sumasto, Hery Syafira, Nurah Teta Puji Rahayu Widiastutik, Dyah Wisnu Istanto Yohanes Kambaru W Zerlinda, Nur