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All Journal Jurnal Kesehatan Reproduksi Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Indonesian Journal of Medicine Journal of Maternal and Child Health Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Jurnal Abdidas Indonesian Basic and Experimental Health Sciences
Laqif, Abdurahman
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Economics, Econometrics & Finance Education Health Professions Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Convalescent Plasma Treatment for Moderate to Critical Ill COVID-19 Patients – A Safe but Futile Treatment: A Non-Randomized Comparative Study Aphridasari, Jatu; Soetjahjo, Bintang; Joko, Agus; Sidharta, Rina; Harsini, Harsini; Arifin, Arifin; Permana, Septian Adi; Saraswati, Kunti; Adhiputri, Artrien; Marwanta, Sri; Laqif, Abdurahman; Danuaji, Rivan
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.4.620

Abstract

Background: In a number of cases of viral infection, convalescent plasma therapy has been effective. Reportedly, the use of convalescent plasma as a therapy for COVID-19 patients with severe and life-threatening disorders is beneficial at this time. This study aims to assess the effectiveness and safety of convalescent plasma transfusions in hospitalized COVID-19 patients. Subjects and Method: This was a clinical trial employing a non-randomized comparative study. A historical control group (21 samples) and convalescent plasma transfusions (21 samples) was selected consecutively from hospitalized COVID-19 patients between May 6th, 2020, and May 6th, 2021 at Dr. Moewardi General Hospital. We assessed and quantified viral clearance in the laboratory. Statistical analysis is performed in SPSS version 20.0. Results: Plasma was taken from fifteen convalescent donors. In the plasma convalescent treatment group, there was a statistically significant difference between outcome and severity degree (p = 0.005). In addition, there was a substantial discrepancy between the result group and the control group (p 0.005). Significant differences in post-treatment NLR between the control and treatment groups (p 0.005). In addition, there were statistically significant differences between the control and treatment groups in post-treatment hsCRP levels (p 0.005). In addition, there were statistically significant differences (p 0.005) between all groups' inflammatory markers and outcomes. Conclusion: Using convalescent plasma to treat patients with COVID-19 is a rather safe practice. Our analysis demonstrated that the administration of convalescent plasma did not enhance survival or clinical outcomes for COVID-19 patients with moderate to severe disease. Keywords: COVID-19, convalescent therapy, critical ill
Edukasi Menopause Sehat bersama Ikatan Istri Dokter Indonesia (IIDI) Menuju Kehidupan Berkualitas Budihastuti, Uki Retno; Melinawati, Eriana; Laqif, Abdurahman; Anggraeni, Asih; Ratnasari, Affi Angelia
Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Vol 7, No 1 (2025): Januari-Juni
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/baktiku.v7i1.13032

Abstract

Menopause is a natural phase that every woman must experience, but it is often accompanied by various physical and emotional complaints that can interfere with daily life and reduce the quality of life. The lack of understanding and access to information makes most women unprepared to face this phase. The purpose of community service activities is to increase the knowledge and awareness of women aged 40 years or older about the concept of healthy menopause. The activity was carried out in a hybrid manner at the Auditorium of the Faculty of Medicine, Sebelas Maret University, involving obstetrics and gynecology specialists, health workers, and members of the IIDI Solo Branch. The implementation method includes counseling, interactive discussions, and evaluation through a pretest and a posttest. The results of the activity showed an increase in the average knowledge score of participants from 82.43 to 85.59, accompanied by an increase in awareness of the importance of early detection and handling of menopausal complaints. These findings confirm that sustainable education is an effective strategy to improve the quality of life of women in the lead-up to old age, in line with the goals of SDG 3, which emphasizes the importance of ensuring healthy lives and well-being for all ages.
Testosterone Levels And Dna Fragmentation Index In Male Undergoing Intrauterine Insemination After Vitamin D3 Supplementation Wijayanti, Agung Sari; Budihastuti, Uki Retno; Melinawati, Eriana; Laqif, Abdurahman; Fahsan, Fatmiyanti
Indonesian Basic and Experimental Health Sciences Vol. 13 No. 1 (2024): November
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol13iss1pp16-22

Abstract

Nutrition is one of the factors that contribute to male infertility. Vitamin D3 are known to affect spermatozoa and usually served in fertility supplementation in doses of 400 and 1000 IU. Low levels of vitamin D3 have been linked to decreased sperm quality and quantity. This research would like to know the effect of Vitamin D3 to the DNA Fragmentation Index (DFI) and Testosterone blood level in men undergoing intrauterine insemination (IUI). This was an analytical observational study with two groups and a pretest-posttest design. Seventeen men aged 20 to 45 who were undergoing the IUI program and did not have diabetes or hypertension are participate in this study. Sperm DFI was determined by using an ELISA method with a DNA Kit. Blood testosterone levels in ng/mL units was measure using ELISA. IBM-SPSS version 22 was used to perform univariate and bivariate analysis on the collected data. The blood level of Vitamin D3 was significantly increased after the intervention of six week Vitamin D3. Meanwhile, this study shows there are no differences in the level of blood testosterone before and after treatment. The DFI was significantly increased in the 400 IU groups.
Mosaic Form of Turner Syndrome Laqif, Abdurahman; Wijayanti, Agung Sari; Moelyo, Annang Giri; Budihastuti, Uki Retno; Melinawati, Eriana
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 1 January 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i1.1826

Abstract

Objective: To report a case of breast growth disorder in a mosaic form of Turner Syndrome. Turner syndrome is a chromosomal condition characterized by small height and primary ovarian insufficiency that affects one in every 2500 female births. Mosaicism is likely to occur when monosomy X develops in only a few cells during development. The clinical presentation of Turner syndrome mosaicism is atypical, with symptom severity varying based on the number of affected cells. This case discusses issues with secondary sex development, including mild hyperandrogenism, and explores how combination hormonal treatment can aid in enhancing secondary sex development. Method: Case Report. Case: A 21-year-old woman presented with chief complaint of the lack of breast enlargement. She exhibited normal genitalia internally and externally and had a regular menstrual cycle. Karyotyping revealed a mosaic pattern of 45, X/46, XX (1 percent/99%) with normal estradiol levels and elevated testosterone levels (indicating mild hyperandrogenism). The patient underwent two cycles of hormone therapy using Ethinyl Estradiol and Drospirenone, resulting in breast growth progression from Tanner stage 1 to Tanner stage 2. Conclusion: Mosaicism in Turner syndrome is plausible, and the severity of clinical symptoms correlates with the number of defective chromosomes. The presentation of Turner syndrome mosaicism varies, and therapy should be tailored to address specific symptoms. While breast development is observed in some girls with Turner Syndrome, instances of breast growth disorder may occur, involving estrogen activity and estrogen receptor sensitivity. Although the exact cause of impaired breast growth remains unknown, administering estrogen in such cases can improve secondary sexual characteristics. Keywords: mild hyperandrogenism, mosaicism, turner syndrome
Comparison of the Incidence of Preterm Labor Between Pregnant Woman with Systemic Lupus Erythematosus Mild and Moderate-Savere Pradani, Yulistiya Kusuma; Bachnas, Muhammad Adianes; Aryoseto, Lukman; Laqif, Abdurahman
Journal of Maternal and Child Health Vol. 9 No. 6 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2024.09.06.05

Abstract

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can affect pregnancy, particularly by increasing the risk of preterm birth. This condition can be influenced by various factors, including the level of SLE activity. Therefore, this study aims to analyze the relationship between preterm birth and the activity level of SLE categorized as mild and moderate-to-severe. Subjects and Method: This study used an analytical observational technique with a cross-sectional research design based on medical record data of pregnant women with SLE at Dr. Moewardi Hospital in the 2021-2023 period, selected through consecutive sampling This study involved 77 pregnant patients with SLE. The dependent variable is preterm labor. The independent variable in this study is pregnant women with SLE. The data were collected by medical record. The data were analyzed by Fisher’s exact test. Results: There was no significant association between the degree of systemic lupus erythematosus activity and preterm labor (p= 0.759). Conclusion: This study shows that there is no significant relationship between the incidence of preterm labor and the degree of systemic lupus erythematosus activity (mild and moderate-to-severe).
Co-Authors ., Darto Abd. Rasyid Syamsuri Adhiputri, Artrien Alifa, Rosita Angelia Ratnasari, Affi Anggraeni, Asih Annang Giri Moelyo Arifin Arifin Aryoseto, Lukman Bachnas, Muhammad Adianes Darto Darto Darto Ediningtyas, Atifa Nadira Eriana Melinawati Fahsan, Fatmiyanti Farras Wahdan, Arib Hafiizha, Attahira Amalia Hermawan Udiyanto Heru Priyanto Heru Priyanto Jatu Aphridasari Joko, Agus Mahandaru, Araafi Hariza Marwanta, Sri Mochammad Imron Awalludin Mushthafa, Mufti Ngudi Insan Ksyatria, Yudhistira Permana, Septian Adi Pradani, Yulistiya Kusuma Prasetya, Hanung Prisasanti, Dympna Prameilita Rachma, Dhea Fitria Rantasari, Affi Angelia Ratnasari, Affi Angelia Rivan Danuaji Saraswati, Kunti Sidharta, Rina Soetjahjo, Bintang Soetrisno Soetrisno Sri Sulistyowati Supriyadi Hari Respati Suryoningrat, Dewanto Teguh Prakosa, Teguh Uki Retno Budihastuti Wasyanto, Trisulo Wijayanti, Agung Sari