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All Journal Jurnal Ilmiah Farmasi Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Reswara: Jurnal Pengabdian Kepada Masyarakat Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Mandala Pengabdian Masyarakat Jurnal Ilmu Kesehatan Masyarakat Indonesia Jurnal Farmasi Tinctura Empowerment Journal Generics: Journal of Research in Pharmacy International Journal of Health and Pharmaceutical (IJHP) Jurnal Farmasi Klinik dan Sains Jurnal Keperawatan Duta Medika Duta Pharma Journal Bengawan :Jurnal Pengabdian Masyarakat Al-Aqlu : Jurnal Matematika, Teknik dan Sains (MJN) Jurnal Pengabdian Masyarakat dan Riset Pendidikan Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Generics : Journal of Research in Pharmacy Journal of Pharmascience
suhesti, iin
D3 Farmasi, Politeknik Indonusa Surakarta
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Optimalisasi Penatalaksanaan Hipertensi melalui Edukasi Penggunaan Nifedipine pada Pasien Lansia Puskesmas Pajang: Penelitian Suhesti, Iin; Izzah, Raihana Nurul; Ardianto, Riko Tri; Tyas, Hesty Hayuning
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 2 (October 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i2.4309

Abstract

Hypertension is a significant public health issue, especially among the elderly, with a high risk of cardiovascular complications. The use of nifedipine as an antihypertensive drug is effective in lowering blood pressure; however, patient understanding of medication use and healthy lifestyle remains limited. This community service activity aimed to improve knowledge of elderly patients at Puskesmas Pajang regarding hypertension and nifedipine use through educational counseling. The method involved interactive material delivery, leaflet distribution, and a question-and-answer session attended by 27 elderly Prolanis members. The results showed an increased understanding of nifedipine’s mechanism of action, side effects, and the importance of a healthy lifestyle summarized by the acronym CERDIK. The interactive discussion provided participants the opportunity to clarify various questions related to hypertension management. Although there were technical limitations such as leaflet shortages and limited discussion time, the activity successfully enhanced health literacy among the elderly and supported therapy adherence. This activity is expected to contribute to hypertension control and complication prevention at the primary healthcare level.
Optimalisasi Penatalaksanaan Hipertensi melalui Edukasi Penggunaan Nifedipine pada Pasien Lansia Puskesmas Pajang: Penelitian Suhesti, Iin; Izzah, Raihana Nurul; Ardianto, Riko Tri; Tyas, Hesty Hayuning
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 2 (October 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i2.4309

Abstract

Hypertension is a significant public health issue, especially among the elderly, with a high risk of cardiovascular complications. The use of nifedipine as an antihypertensive drug is effective in lowering blood pressure; however, patient understanding of medication use and healthy lifestyle remains limited. This community service activity aimed to improve knowledge of elderly patients at Puskesmas Pajang regarding hypertension and nifedipine use through educational counseling. The method involved interactive material delivery, leaflet distribution, and a question-and-answer session attended by 27 elderly Prolanis members. The results showed an increased understanding of nifedipine’s mechanism of action, side effects, and the importance of a healthy lifestyle summarized by the acronym CERDIK. The interactive discussion provided participants the opportunity to clarify various questions related to hypertension management. Although there were technical limitations such as leaflet shortages and limited discussion time, the activity successfully enhanced health literacy among the elderly and supported therapy adherence. This activity is expected to contribute to hypertension control and complication prevention at the primary healthcare level.
Optimalisasi Penatalaksanaan Hipertensi melalui Edukasi Penggunaan Nifedipine pada Pasien Lansia Puskesmas Pajang: Penelitian Suhesti, Iin; Izzah, Raihana Nurul; Ardianto, Riko Tri; Tyas, Hesty Hayuning
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 2 (October 202
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i2.4309

Abstract

Hypertension is a significant public health issue, especially among the elderly, with a high risk of cardiovascular complications. The use of nifedipine as an antihypertensive drug is effective in lowering blood pressure; however, patient understanding of medication use and healthy lifestyle remains limited. This community service activity aimed to improve knowledge of elderly patients at Puskesmas Pajang regarding hypertension and nifedipine use through educational counseling. The method involved interactive material delivery, leaflet distribution, and a question-and-answer session attended by 27 elderly Prolanis members. The results showed an increased understanding of nifedipine’s mechanism of action, side effects, and the importance of a healthy lifestyle summarized by the acronym CERDIK. The interactive discussion provided participants the opportunity to clarify various questions related to hypertension management. Although there were technical limitations such as leaflet shortages and limited discussion time, the activity successfully enhanced health literacy among the elderly and supported therapy adherence. This activity is expected to contribute to hypertension control and complication prevention at the primary healthcare level.
STABILITY TEST OF FACIAL MOISTURIZING CREAM FROM SNAIL SLIME (Achatina fulica) WITH VARIATIONS IN STEARIC ACID Suhesti, Iin; Putri, Vania Santika; Hidayah, Dian Nurul
Medical Journal of Nusantara Vol. 4 No. 3 (2025): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v4i3.1761

Abstract

The skin is exposed to free radicals from the environment every day which can cause premature aging. The aging process is characterized by decreased sweat gland production, followed by decreased skin moisture due to reduced skin elasticity and the skin's ability to retain water, so the skin needs moisturizer. Snail slime (Achatina fulica) contains active substances glycosaminoglycan and allantoin with a concentration of 3% functioning as a tightener, softener and moisturizer for facial skin and contains achasin protein which has antibacterial activity against Propionibacterium acnes with an inhibitory power of 16.0 mm ± 2.6 at a concentration of 11%. This study aims to determine the effect of achasin protein on Propionibacterium acnes on skin elasticity.to know the variation of stearic acid concentration and stability of facial moisturizing cream from snail slime. This study used an experimental method with 3% snail slime as the active ingredient and stability testing was carried out using 2 methods, namely cycling test and centrifugation. Snail slime was formulated into a cream preparation with varying stearic acid concentrations of 5%, 7%, 9% and 11%. Based on the results of the stability test using the cycling test method, it was found that all cream formulas were physically stable because they did not experience phase separation, while based on the results of the stability test using the centrifugation method, it was found that the cream in formula 4 was more physically stable when compared to formulas 1, 2 and 3 because it experienced phase separation at the 150th minute. Conclusion: The resulting facial moisturizer cream was stable in the cycling test method but not stable in the centrifugation method.
STABILITY TEST OF FACIAL MOISTURIZING CREAM FROM SNAIL SLIME (Achatina fulica) WITH VARIATIONS IN STEARIC ACID Suhesti, Iin; Putri, Vania Santika; Hidayah, Dian Nurul
Medical Journal of Nusantara Vol. 4 No. 3 (2025): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v4i3.1761

Abstract

The skin is exposed to free radicals from the environment every day which can cause premature aging. The aging process is characterized by decreased sweat gland production, followed by decreased skin moisture due to reduced skin elasticity and the skin's ability to retain water, so the skin needs moisturizer. Snail slime (Achatina fulica) contains active substances glycosaminoglycan and allantoin with a concentration of 3% functioning as a tightener, softener and moisturizer for facial skin and contains achasin protein which has antibacterial activity against Propionibacterium acnes with an inhibitory power of 16.0 mm ± 2.6 at a concentration of 11%. This study aims to determine the effect of achasin protein on Propionibacterium acnes on skin elasticity.to know the variation of stearic acid concentration and stability of facial moisturizing cream from snail slime. This study used an experimental method with 3% snail slime as the active ingredient and stability testing was carried out using 2 methods, namely cycling test and centrifugation. Snail slime was formulated into a cream preparation with varying stearic acid concentrations of 5%, 7%, 9% and 11%. Based on the results of the stability test using the cycling test method, it was found that all cream formulas were physically stable because they did not experience phase separation, while based on the results of the stability test using the centrifugation method, it was found that the cream in formula 4 was more physically stable when compared to formulas 1, 2 and 3 because it experienced phase separation at the 150th minute. Conclusion: The resulting facial moisturizer cream was stable in the cycling test method but not stable in the centrifugation method.
Penggunaan Antibiotik untuk Penanganan Ulkus dan Gangren Diabetikum Pasien Rawat Inap di Rumah Sakit Riyan Stiyanto; Iin Suhesti
Journal of Pharmascience Vol. 7 No. 2 (2020): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8578

Abstract

Penyakit Diabetes melitus yang tidak dikelola dengan baik dapat menyebabkan komplikasi dan membahayakan kehidupan pengidapnya. Salah satu komplikasi diabetik yang sering terjadi adalah neuropati (kerusakan syaraf) di kaki yang menyebabkan ulkus kaki, infeksi, dan bahkan keharusan untuk amputasi kaki. Penelitian ini bertujuan untuk mengidentifikasi persentase penggunaan antibiotika empiris yang rasional serta pengaruhnya terhadap outcome terapi pada pasien Diabetes melitus dengan ulkus dan gangren di RSUD Dr Moewardi Surakarta dan RSUD Bagas Waras Klaten. Penelitian ini merupakan penelitian observasional dengan pengambilan data pada penelitian dilakukan secara retrospektif dan prospektif selama periode Januari sampai Agustus 2018. Ketidakrasionalan penggunaan antibiotika empiris dievaluasi dengan metode Gyssens. Sebanyak 36 pasien yang memenuhi kriteria inklusi 75% pasien mendapatkan terapi antibiotika empiris yang rasional dan 25% pasien mendapatkan terapi antibiotika empiris yang tidak rasional. Uji Chi Square dengan taraf kepercayaan 5% (p < 0,05) digunakan untuk membandingkan rasionalitas pengunaan antibiotika terhadap outcome terapi. Hasil Fisher’s Exact Test (Two Tailed) menunjukkan bahwa ada hubungan/pengaruh antara rasionalitas penggunaan antibiotika empiris dengan outcome terapi tetapi pemberian antibiotika empiris tidak berpengaruh pada angka leukosit bagi pasien, baik di RSUD Bagas Waras Klaten maupun RSUD dr. Moewardi Surakarta.Diabetes mellitus that is not managed properly can cause complications to endanger life. One of the diabetic complications that often occurs is foot neuropathy (nerve damage) inducing foot ulcers, infections, and even the necessity for a leg amputation. This study aims to determine the percentage of rational use of empirical antibiotics and their effects on outcomes therapy of diabetes mellitus patient with ulcers and gangrene in RSUD dr. Moewardi Hospital Surakarta and Bagas Waras Hospital Klaten. This study is an observational study with data collection in the study carried out retrospectively and prospectively from January to August 2018. The irrationality of using empirical antibiotics evaluated by the Gyssens method. Thirty six patients were enrolled and 75% of them treated with rational and empirical antibiotic therapy,. Chi-Square Test with a confidence level of 5% (p <0.05) used to compare the rationality of antibiotic use to the therapeutic outcome, the results of the Fisher Exact Test (Two-Tailed) indicated that there were relationship/influence between the rationality of using empirical antibiotics and outcomes therapy, but there was no influence between the rationality of using empirical antibiotics and leucocyte both in RSUD Bagas Waras Klaten and RSUD dr. Moewardi Surakarta.Keywords: Diabetes mellitus, therapeutic outcome, empirical antibiotic rationality
Formulation and Physical Stability Testing of Exfoliating Gel and Moisturizing Gel From Sugarcane Bagasse Extract Iin Suhesti; Ester Dwi Antari; Syafa Chasna Nasrina; Marzela Pancaya Putra
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 1 (2025): February 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i1.397

Abstract

Sugarcane bagasse extract (Saccharum officinarum Linn.) has high antioxidant activity due to its phenolic compounds, which are beneficial for moisturizing dry skin, smoothing the skin, and combating free radicals. This study aimed to evaluate the physical stability of exfoliating and moisturizing gel formulations containing sugarcane bagasse extract at concentrations of 1%, 3%, and 5% using the cycling test method over six cycles (12 days) at temperatures of ±4°C and ±40°C. Parameters tested included organoleptic properties, homogeneity, pH, viscosity, spreadability, and adhesiveness. The results showed that the formulations without extract (control) and those with 1% extract concentration met the physical stability parameters and remained stable throughout the cycling test, with viscosity ranging from 13,665.7 to 20,180.6 cPs, pH between 4.76 and 5.43, spreadability from 3.25 to 5.64 cm, and adhesiveness from 0.42 to 1.52 seconds. In contrast, formulations with 3% and 5% extract concentrations exhibited physical instability, such as changes in pH, viscosity, and spreadability, failing to pass the stability test cycles.
Formulation and Physical Stability Testing of Exfoliating Gel and Moisturizing Gel From Sugarcane Bagasse Extract Iin Suhesti; Ester Dwi Antari; Syafa Chasna Nasrina; Marzela Pancaya Putra
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 1 (2025): February 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i1.397

Abstract

Sugarcane bagasse extract (Saccharum officinarum Linn.) has high antioxidant activity due to its phenolic compounds, which are beneficial for moisturizing dry skin, smoothing the skin, and combating free radicals. This study aimed to evaluate the physical stability of exfoliating and moisturizing gel formulations containing sugarcane bagasse extract at concentrations of 1%, 3%, and 5% using the cycling test method over six cycles (12 days) at temperatures of ±4°C and ±40°C. Parameters tested included organoleptic properties, homogeneity, pH, viscosity, spreadability, and adhesiveness. The results showed that the formulations without extract (control) and those with 1% extract concentration met the physical stability parameters and remained stable throughout the cycling test, with viscosity ranging from 13,665.7 to 20,180.6 cPs, pH between 4.76 and 5.43, spreadability from 3.25 to 5.64 cm, and adhesiveness from 0.42 to 1.52 seconds. In contrast, formulations with 3% and 5% extract concentrations exhibited physical instability, such as changes in pH, viscosity, and spreadability, failing to pass the stability test cycles.
Formulation and Physical Stability Testing of Exfoliating Gel and Moisturizing Gel From Sugarcane Bagasse Extract Iin Suhesti; Ester Dwi Antari; Syafa Chasna Nasrina; Marzela Pancaya Putra
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 1 (2025): February 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i1.397

Abstract

Sugarcane bagasse extract (Saccharum officinarum Linn.) has high antioxidant activity due to its phenolic compounds, which are beneficial for moisturizing dry skin, smoothing the skin, and combating free radicals. This study aimed to evaluate the physical stability of exfoliating and moisturizing gel formulations containing sugarcane bagasse extract at concentrations of 1%, 3%, and 5% using the cycling test method over six cycles (12 days) at temperatures of ±4°C and ±40°C. Parameters tested included organoleptic properties, homogeneity, pH, viscosity, spreadability, and adhesiveness. The results showed that the formulations without extract (control) and those with 1% extract concentration met the physical stability parameters and remained stable throughout the cycling test, with viscosity ranging from 13,665.7 to 20,180.6 cPs, pH between 4.76 and 5.43, spreadability from 3.25 to 5.64 cm, and adhesiveness from 0.42 to 1.52 seconds. In contrast, formulations with 3% and 5% extract concentrations exhibited physical instability, such as changes in pH, viscosity, and spreadability, failing to pass the stability test cycles.
The Effect of Varying Concentrations of Mugwort Leaf Extract (Artemisia vulgaris L.) on SPF and Cream Physical Stability Umi Nafisah; Adeta Selvia Devi; Iin Suhesti
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.793

Abstract

Mugwort (Artemisia vulgaris L.) has antioxidant activity that can neutralize free radicals on the skin and also has sunscreen activity to protect the skin from UV exposure. This study highlights the benefits of the mugwort plant, which are currently unknown to the general public, requiring investigation into the formulation of its topical cream. This research aims to determine the stability of mugwort leaf extract cream and its SPF value. The extraction process uses the maceration method with 96% ethanol as the solvent. This study employed variations in mugwort leaf extract concentrations across formulas, starting from the control at 0% extract and increasing to 0.5%, 1%, 1.5%, and 2%. The organoleptic test results of the cream in the control formula showed a white color and green color in F1 to F4, with a characteristic smell and a semi-solid texture. The physical quality test for homogeneity indicates that all formulas are homogeneous. The pH test results of the formulation obtained values of 4,74-5,49, which meet the skin pH standard. The spreadability results obtained values of 6,15-6,38 cm. The cream's viscosity was in the range of 4,870-4,950 cPs. The hedonic test results showed that panelists preferred F1 with an extract concentration of 0.5%. The SPF test yielded scores ranging from 6,45 to 14,71. All formulations were able to preserve the physical quality stability of the preparations, according to the findings of the stability test conducted using the cycling test.
Co-Authors Achmad Chasan Fadlan Afifatus Salamah Aisyah Nur Hidayah Alya Putri Pasakti Amalia, Annora Rizky Anisa Hariyani Annisa Diyan Meitasari Aptika Oktaviana Trisna Dewi Arofah Frisca Sahara Ayu Wulandari Cici Hana Safitri Dewi Weni Sari Dian Nurul Hidayah Diaz Eka Pangesti Dicky Saputra Dinar Azizah Dita Nurhaliza Kurniawati Diyan Sakti Purwanto Diyan Sakti Purwanto Erlin Devi Isnaini Ester Dwi Antari Fara Istiq Farina Mahaloka Fira Wirawati Gilang Ramadhan Putra Susilo Ihsan Rohdiyanto Isnaini Milarsih Isnaini Putri Indriyani Izzah, Raihana Nurul Kiky Adhianna Sulistyawati Kustini, Henny Lailatul Mujtahidah Maya Tri Nugroho Meitasari, Annisa Diyan Nafisah, Umi Nana Yunita Patricia Nayla Salsabila Nia Tri Mandasari Nichy Eka Putri Niken Ayuningtyas Nila Efa Sulistiana Nory Bagus Wardani Priska Andini Puput Muryanti Ika Safitri Purwanto, Diyan Sakti Putri, Vania Santika Riyan Setiyanto Riyan Stiyanto Rury Ayu Rahmawati Setiyanto, Riyan Syalva Oktaviyana Aswandari Umi Nafisah Yunita Dian Permata Sari