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The Effect of Varying Concentrations of Mugwort Leaf Extract (Artemisia vulgaris L.) on SPF and Cream Physical Stability Umi Nafisah; Adeta Selvia Devi; Iin Suhesti
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.793

Mugwort (Artemisia vulgaris L.) has antioxidant activity that can neutralize free radicals on the skin and also has sunscreen activity to protect the skin from UV exposure. This study highlights the benefits of the mugwort plant, which are currently unknown to the general public, requiring investigation into the formulation of its topical cream. This research aims to determine the stability of mugwort leaf extract cream and its SPF value. The extraction process uses the maceration method with 96% ethanol as the solvent. This study employed variations in mugwort leaf extract concentrations across formulas, starting from the control at 0% extract and increasing to 0.5%, 1%, 1.5%, and 2%. The organoleptic test results of the cream in the control formula showed a white color and green color in F1 to F4, with a characteristic smell and a semi-solid texture. The physical quality test for homogeneity indicates that all formulas are homogeneous. The pH test results of the formulation obtained values of 4,74-5,49, which meet the skin pH standard. The spreadability results obtained values of 6,15-6,38 cm. The cream's viscosity was in the range of 4,870-4,950 cPs. The hedonic test results showed that panelists preferred F1 with an extract concentration of 0.5%. The SPF test yielded scores ranging from 6,45 to 14,71. All formulations were able to preserve the physical quality stability of the preparations, according to the findings of the stability test conducted using the cycling test.

The Effect of Varying Concentrations of Mugwort Leaf Extract (Artemisia vulgaris L.) on SPF and Cream Physical Stability Umi Nafisah; Adeta Selvia Devi; Iin Suhesti
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.793

Mugwort (Artemisia vulgaris L.) has antioxidant activity that can neutralize free radicals on the skin and also has sunscreen activity to protect the skin from UV exposure. This study highlights the benefits of the mugwort plant, which are currently unknown to the general public, requiring investigation into the formulation of its topical cream. This research aims to determine the stability of mugwort leaf extract cream and its SPF value. The extraction process uses the maceration method with 96% ethanol as the solvent. This study employed variations in mugwort leaf extract concentrations across formulas, starting from the control at 0% extract and increasing to 0.5%, 1%, 1.5%, and 2%. The organoleptic test results of the cream in the control formula showed a white color and green color in F1 to F4, with a characteristic smell and a semi-solid texture. The physical quality test for homogeneity indicates that all formulas are homogeneous. The pH test results of the formulation obtained values of 4,74-5,49, which meet the skin pH standard. The spreadability results obtained values of 6,15-6,38 cm. The cream's viscosity was in the range of 4,870-4,950 cPs. The hedonic test results showed that panelists preferred F1 with an extract concentration of 0.5%. The SPF test yielded scores ranging from 6,45 to 14,71. All formulations were able to preserve the physical quality stability of the preparations, according to the findings of the stability test conducted using the cycling test.

Formulasi dan Evaluasi Fisik Masker Gel Peel-Off Ekstrak Etanol Daun Jamblang (Syzygium cumini (L.) Skeels) dengan Variasi Konsentrasi PVA Ester Dwi Antari; Diyan Sakti Purwanto; IIn Suhesti; Nia Tri Mandasari
Generics: Journal of Research in Pharmacy Vol 6, No 2 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i2.30403

Tanaman jamblang merupakan tanaman yang bermanfaat sebagai antioksidan. Pemanfaatan antioksidan pada daun jamblang sebagai perawatan kulit untuk pencegahan penuaan dini. Salah satu produk kosmetik yang banyak dijumpai adalah masker gel peel off. Penelitian ini bertujuan untuk mengetahui formulasi dan evaluasi fisik masker gel peel off ekstrak daun jamblang dengan variasi konsentrasi PVA untuk menghasilkan masker yang memenuhi persyaratan. Penelitian ini menggunakan metode eksperimen. Masker gel peel off ekstrak daun jamblang dibuat dengan menggunakan konsentrasi PVA, F1 8%, F2 12% dan F3 16%. Masker gel peel off diuji fisik meliputi uji organoleptis, homogenitas, pH, daya sebar, daya lekat, viskositas, waktu kering dan diuji menggunakan SPSS. Hasil uji organoleptis ketiga formula memiliki tekstur semisolid, warna coklat kemerahan dan aroma khas jamblang. Semua formula masker gel peel off memenuhi syarat uji pH, daya lekat, daya sebar, viskositas, dan waktu kering. Uji evaluasi fisik gel yang meliputi uji pH, daya sebar, daya lekat, viskositas, dan waktu mengering telah menunjukkan memenuhi persyaratan pada formula 1, 2, dan 3. Berdasarkan hasil uji analisis data menggunakan One Way Anova dan Kruskal Wallis dapat disimpulkan bahwa variasi konsentrasi PVA berpengaruh terhadap uji daya sebar, daya lekat, viskositas, waktu kering dan tidak berpengaruh terhadap uji pH.

The Effectiveness Test Of Natural Hair Growth Tonic: Avemor (Aloe Vera And Moringa Oleifera) For Thickening Hair And Anti-Licknes Iin Suhesti; Annisa Diyan Meitasari; Nila Efa Sulistiana; Dinar Azizah
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 1 (2024): February 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i1.316

Avemor (Aloe vera and Moringa oleifera) is a natural hair growth tonic manufactured with a combination of aloe vera gel and dried moringa leaf extract as its active ingredients. Aloe vera includes a variety of vitamins and minerals, including vitamins A and C, amino acids, copper, inositol, and others. The extract from moringa leaves also includes tanins, vital amino acids, vitamin C, vitamin E, and other nutrients. One of the products with 2% minoxidil is employed as a positive control. Several hair diseases are treated off-label with the powerful arteriol vasoconstrictor minoxidil, which can also promote hair growth. In order to determine the effectiveness of Natural Hair Growth Tonic, tests were done on male New Zealand white rabbit hair. Avemor (Aloe vera and Moringa oleifera) is one of the products containing 2% minoxidil, with variations in the content of dried moringa leaf extracts of 2%, 4%, and 6% in comparison to the positive control. On the backs of five rabbits, six test regions were created, and each area received a different treatment every day using a sample volume of 0.5 ml. Results of the Natural Hair Growth Tonic's physical evaluation: Avemor (Aloe vera and Moringa oleifera) has a liquid shape, a distinct aroma, a pH of 6, and is homogeneous with the yellow-golden color of the formulae 1 and 2 as well as the golden brown in the formula 3. It also varies in the concentration of the dried moringa leaf extracts. Formula 4 (negative control) has the appearance of a liquid, is dazzling white in color, and emits a distinct odor. Additionally, formula 5 (positive control) has a liquid-like consistency, a vivid yellowish color, and a distinguishable scent. The average reserve viscosity for formula 1 was 2.96 ± 0.14 cPs, for formula 2 it was 2.99 ± 0.10 cPs, and for formula 3 it was 4.05 ± 0.07 cPs. Formula 4 (negative control) had a value 2.96 ± 0.10 cPs, and formula 5 (positive control) had a value of 1.82 ± 0.03 cPs. The average result of rabbit hair growth on the seventh day for treatment 1 is 0.22 ± 0.17 cm, treatment 2 is 0.30 ± 0.23 cm, treatment 3 is 0.42 ± 0.42 cm, treatment 4 is 0.58 ± 0.47 cm, treatment 5 is 0.68 ± 0.36 cm, and treatment 6 is 0.90 ± 0.42 cm. On the 14th day of treatment 1, the average result of rabbit hair growth was 0.43 ± 0.06 cm; on the same day, treatment 2, 0.27± 0.18 cm; on the same day, treatment 3, 0.42 ± 0.33 cm; on the same day, treatment 4, 0.77 ± 0.22 cm; on the same day, treatment 5, 0.28 ± 0.24 cm; and on the same day, treatment 6, 0.43 ± 0.38 cm. The average length of rabbit hair on the 21st day for treatment 1 was 0.43 ± 0.26 cm, for treatment 2 was 0.73 ± 0.19 cm, for treatment 3 was 0.32 ± 0.23 cm, for treatment 4 was 0.48 ± 0.31 cm, for treatment 5 was 0.13 ± 0.17 cm, and for treatment 6 was 0,43 ± 0.30 cm.

Formulasi dan Evaluasi Fisik Masker Gel Peel-Off Ekstrak Etanol Daun Jamblang (Syzygium cumini (L.) Skeels) dengan Variasi Konsentrasi PVA Ester Dwi Antari; Diyan Sakti Purwanto; IIn Suhesti; Nia Tri Mandasari
Generics: Journal of Research in Pharmacy Vol 6, No 2 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i2.30403

Tanaman jamblang merupakan tanaman yang bermanfaat sebagai antioksidan. Pemanfaatan antioksidan pada daun jamblang sebagai perawatan kulit untuk pencegahan penuaan dini. Salah satu produk kosmetik yang banyak dijumpai adalah masker gel peel off. Penelitian ini bertujuan untuk mengetahui formulasi dan evaluasi fisik masker gel peel off ekstrak daun jamblang dengan variasi konsentrasi PVA untuk menghasilkan masker yang memenuhi persyaratan. Penelitian ini menggunakan metode eksperimen. Masker gel peel off ekstrak daun jamblang dibuat dengan menggunakan konsentrasi PVA, F1 8%, F2 12% dan F3 16%. Masker gel peel off diuji fisik meliputi uji organoleptis, homogenitas, pH, daya sebar, daya lekat, viskositas, waktu kering dan diuji menggunakan SPSS. Hasil uji organoleptis ketiga formula memiliki tekstur semisolid, warna coklat kemerahan dan aroma khas jamblang. Semua formula masker gel peel off memenuhi syarat uji pH, daya lekat, daya sebar, viskositas, dan waktu kering. Uji evaluasi fisik gel yang meliputi uji pH, daya sebar, daya lekat, viskositas, dan waktu mengering telah menunjukkan memenuhi persyaratan pada formula 1, 2, dan 3. Berdasarkan hasil uji analisis data menggunakan One Way Anova dan Kruskal Wallis dapat disimpulkan bahwa variasi konsentrasi PVA berpengaruh terhadap uji daya sebar, daya lekat, viskositas, waktu kering dan tidak berpengaruh terhadap uji pH.

Household Drug Use Safety in Terms of Knowledge, Behavior, and Storage Reski Putri Sapitri; Annora Rizky Amalia; Iin Suhesti
Jurnal Keperawatan Duta Medika Vol. 6 No. 2 (2026): Jurnal Keperawatan Duta Medika
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/t23as046

Introduction:Household drug management, including proper knowledge, behavior, and storage practices, is essential for ensuring medication safety and preventing adverse drug events. Community-level self-medication practices without adequate understanding pose significant health risks. Objectives: This study aims to determine the level of knowledge, behavior, and drug storage practices among the community of Karan Kidul Village, Gayamdompo, Karanganyar, and to analyze their relationships with household drug use safety. Method: This was a non-experimental descriptive survey study using a cross-sectional approach. A total of 165 respondents were selected using the Slovin formula from a population of 280 residents. Data were collected through validated and reliable questionnaires covering knowledge, behavior, and drug storage, and were analyzed using univariate and bivariate Chi-Square tests. Results: The majority of respondents demonstrated good knowledge (42.4%), good behavior (43.6%), and sufficient drug storage practices (51.5%). Safe drug use was reported in 85.5% of respondents. Chi-Square analysis revealed a significant relationship between knowledge, behavior, and drug storage with household drug use safety, with a p-value of 0.000 (< 0.05) for all three variables. Conclusion: Improving community knowledge, appropriate drug use behavior, and proper drug storage practices may contribute to safer household medication management. Community education on rational drug use, Expired Date versus Beyond Use Date distinctions, and proper storage techniques is strongly recommended. Keywords: Beyond Use Date, drug storage, household drug use safety, knowledge, self-medication

Household Drug Use Safety in Terms of Knowledge, Behavior, and Storage Reski Putri Sapitri; Annora Rizky Amalia; Iin Suhesti
Jurnal Keperawatan Duta Medika Vol. 6 No. 2 (2026): Jurnal Keperawatan Duta Medika
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/t23as046

Introduction:Household drug management, including proper knowledge, behavior, and storage practices, is essential for ensuring medication safety and preventing adverse drug events. Community-level self-medication practices without adequate understanding pose significant health risks. Objectives: This study aims to determine the level of knowledge, behavior, and drug storage practices among the community of Karan Kidul Village, Gayamdompo, Karanganyar, and to analyze their relationships with household drug use safety. Method: This was a non-experimental descriptive survey study using a cross-sectional approach. A total of 165 respondents were selected using the Slovin formula from a population of 280 residents. Data were collected through validated and reliable questionnaires covering knowledge, behavior, and drug storage, and were analyzed using univariate and bivariate Chi-Square tests. Results: The majority of respondents demonstrated good knowledge (42.4%), good behavior (43.6%), and sufficient drug storage practices (51.5%). Safe drug use was reported in 85.5% of respondents. Chi-Square analysis revealed a significant relationship between knowledge, behavior, and drug storage with household drug use safety, with a p-value of 0.000 (< 0.05) for all three variables. Conclusion: Improving community knowledge, appropriate drug use behavior, and proper drug storage practices may contribute to safer household medication management. Community education on rational drug use, Expired Date versus Beyond Use Date distinctions, and proper storage techniques is strongly recommended. Keywords: Beyond Use Date, drug storage, household drug use safety, knowledge, self-medication

FORMULASI DAN EVALUASI FISIK SEDIAAN KRIM EKSTRAK DAUN SINGKONG (Manihot utilissima Pohl.) DENGAN VARIASI ASAM STEARAT DAN TRIETANOLAMIN SEBAGAI EMULGATOR Riyan Setiyanto; Maya Tri Nugroho; Iin Suhesti
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 6 No. 1 (2022): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v6i1.221

Cassava leaves (Manihot utilissima Pohl.) contain flavonoid compounds, saponins, and tannins which have antibacterial properties. To facilitate its use, it is made in the form of a cream dosage form. This study aims to determine the formulation, physical evaluation, and the effect of variations in concentrations of stearic acid and triethanolamine on the physical properties of cassava leaf extract cream (Manihot utilissima Pohl.). This study uses an experimental method. Extracts were made using the maceration method with 70% ethanol. The cream was made in three formulas with different concentrations of stearic acid and triethanolamine, namely F1=2.5%:2%, F2=5%:3%, and F3=7.5%:4%. The results of the organoleptic test showed that the cream preparation was blackish green. The homogeneity test showed that the preparation was homogeneous, the pH test of the cream preparation was F1=6,20±0,15, F2=6.64±0.60, and F3=6.87±0.03, F2 and F3 did not meet the skin pH requirements. ie 4.5-6.5. The adhesion test F1=1.39±0.33, F2=2.03±0.42, and F3=2.51±0.38 did not match the parameters. The dispersion test was F1=6 cm±0.28, F2=5.16 cm±0.57, and F3= 3.66 cm±0.14. F1 and F2 meet the requirements of the adhesion test. In the protective power test, it was concluded that the cream could not provide good protection. The cream type test showed that the cream was of the M/A type. The results of the hedonic test that were most favored by panelists were formula 3. The data obtained were processed using SPSS with One Way ANOVA and Kruskal-Wallis methods. Based on the results of the analysis it can be concluded that variations in stearic acid and triethanolamine have a significant influence on the results of the evaluation of pH adhesion and dispersibility

PROFILE OF ANTIDIABETES USE IN TYPE II DIABETES PATIENTS IN THE OUTPATIENT PHARMACY INSTALLATION OF THE UNS HOSPITAL Dewi Weni Sari; Puput Muryanti Ika Safitri; Isnaini Milarsih; Iin Suhesti
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 8 No. 2 (2024): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v8i2.227

Elevate blood sugar is a defining feature of the dangerous illness know as diabetes mellitus. At the 12th level, the death rate form diabetes mellitus is 366 million. In the absence of any intervention, this number is projected to rise to 522 million in 2025, placing it in seventh place. Finding out the profile of antidiabetic medication use in the UNS Hospital outpatient pharmacy is the goal of this study. All outpatients at the UNS Hospital who were diagnosed with type 2 diabetes mellitus between June and July of 2023 comprised the research population. Microsoft office excel was used to tabulate the research data, and percentages were then derived by data processing. According to the findings of the study on the profile of diabetes medication use, metformine is the most commonly used drug in the biguanid group (16%), and metformin and glimepiride is the most commonly used drug combination (11%), both of which are sulfonylureas. Kata kunci: Type 2 diabetes mellitus, drug use profile, Hospital

EDUKASI TENTANG HIPERTENSI SEBAGAI UPAYA PENCEGAHAN KOMPLIKASI PADA LANSIA DI KELURAHAN KRATON, MAGETAN, JAWA TIMUR Iin Suhesti; Salsabila Valentanisa; Achmad Chasan Fadlan; Afifatus Salamah; Alya Putri Pasakti; Fara Istiq Farina Mahaloka; Fira Wirawati; Ihsan Rohdiyanto; Lailatul Mujtahidah; Martha Ayu Setyotini; Nana Yunita Patricia; Nayla Salsabila; Niken Ayuningtyas; Nory Bagus Wardani
Empowerment Journal Vol. 6 No. 2 (2026): SEPTEMBER
Publisher : Universitas 'Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30787/empowerment.v6i2.2634

Hipertensi merupakan salah satu penyakit tidak menular yang banyak dialami oleh lanjut usia dan menjadi penyebab utama berbagai komplikasi, seperti stroke, penyakit jantung, dan gagal ginjal. Rendahnya pengetahuan mengenai faktor risiko, pencegahan, dan pengendalian hipertensi dapat meningkatkan risiko terjadinya komplikasi. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan kesadaran lanjut usia mengenai hipertensi sebagai upaya pencegahan komplikasi di Kelurahan Kraton, Kecamatan Maospati, Kabupaten Magetan, Jawa Timur. Metode yang digunakan meliputi edukasi kesehatan melalui penyampaian materi dan pembagian leaflet, serta pemeriksaan kesehatan berupa pengukuran tekanan darah, berat badan, tinggi badan, lingkar pinggang, kadar gula darah, dan kadar kolesterol. Kegiatan dilaksanakan pada bulan Juni 2026 dengan melibatkan mahasiswa dan kader Pos Pelayanan Terpadu Lanjut Usia. Hasil kegiatan menunjukkan bahwa seluruh rangkaian kegiatan terlaksana dengan baik dan peserta mengikuti edukasi secara antusias melalui diskusi serta sesi tanya jawab. Penyampaian materi dan leaflet memberikan informasi mengenai faktor risiko, komplikasi, upaya pencegahan, pentingnya kepatuhan terhadap pengobatan, serta pengendalian tekanan darah secara rutin. Kegiatan ini juga memperkuat kolaborasi antara mahasiswa dan kader kesehatan dalam mendukung upaya promotif dan preventif di masyarakat. Dengan demikian, edukasi hipertensi dapat menjadi salah satu strategi promotif dan preventif untuk meningkatkan kesadaran lanjut usia dalam menerapkan pola hidup sehat dan mencegah terjadinya komplikasi hipertensi.

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