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Training on Determining Beyond Use Date (BUD) on Pharmacy Practice at Surabaya Health Vocational School Wibowo, Teguh Setiawan; Negara, Sri Bintang Sahara Mahaputra Kusuma
Jurnal Pengabdian Masyarakat Formosa Vol. 3 No. 2 (2024): April 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/jpmf.v3i2.9203

Abstract

All drugs must be injected immediately after being prepared because the life of the drug can be shorter and it no longer refers to the Expiration Date (ED). If the medicine is not injected immediately, then to maintain the quality of the medicine before the BUD limit is to give the medicine vial a mark of the date and time the medicine was prepared and it must be stored according to storage requirements. The method used theoretical presentation, question/answer, discussion and practice offline in one of Surabaya Health Vocational School classrooms. The results are the community service activities through training on determining the Beyond Use Date (BUD) in Pharmacy practice at the Surabaya Health Vocational School received a positive response and the participants were very enthusiastic. It is hoped that there will be special standards established by the Surabaya Health Vocational School to help provide understanding regarding determining the Beyond Use Date (BUD) in the pharmaceutical practice and further collaboration with the Health Service, Community Health Center or Hospital on an ongoing basis.
Hubungan Tingkat Pengetahuan dengan Perilaku Penggunaan Antibiotik Tanpa Resep pada Mahasiswa Fakultas Ilmu Kesehatan di Universitas Muhammadiyah Lamongan Al wahida, Nur Aini; Octavia, Devi Ristian; Sahara, Sri Bintang
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i12.7008

Abstract

Antibiotik adalah obat yang digunakan untuk mengatasi infeksi bakteri. penggunaan yang tidak wajar dapat memicu terjadinya resistensi antibiotik. Penggunaan antibiotik yang tepat dipengaruhi oleh Pengetahuan dan Perilaku dalam menggunakan antibiotic. Tujuan penelitian ini untuk mengetahui hubungan tingkat pengetahuan dengan perilaku pengunaan antibiotik tanpa resep pada mahasiswa fakultas ilmu kesehatan di Universitas muhammadiyah Lamongan dalam menggunakan antibiotik tanpa resep. Desain penelitian ini adalah deskriptif korelatif. populasi sebanyak 347 Responden, menggunakan purposive sampling yang dilakukan bulan Febuari 2024. Instrumen yang digunakan adalah kuesioner yang sudah diuji validitas dan realibilitas. Analisis korelasi dilakukan uji korelasi rank Spearman. Hasil penelitian menujukkan menunjukan bahwa hubungan tingkat pengetahuan tentang penggunaan antibiotik tanpa resep pada mahasiswa Fakultas Ilmu Kesehatan di Universitas Muhammadiyah Lamongan termasuk dalam kategori pengetahuan baik sebesar 152 orang dengan persentase 81,7%, Perilaku penggunaan antibiotik di kategori perilaku baik sebesar 130 orang dengan presentase 69,8%. Terdapat hubungan yang bermakna dengan signifikansi sebesar 0,01, koefisien korelasi sebesar 0,231 dan arah korelasi positif (+) yang artinya terdapat hubungan yang signifikan antara pengetahuan mahasiswa Fakultas Ilmu Kesehatan di Universitas Muhammadiyah Lamongan dengan perilaku pengguaan antibiotik dengan kekuatan yang lemah.
In Vitro Antibacterial Activity and Minimum Inhibitory Concentration of Citrus aurantifolia Lime Peel Ethanolic Extract against Propionibacterium acnes Putri, Amalia Eka; Negara, Sri Bintang Sahara Mahaputra Kusuma
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 03 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v2i02.18

Abstract

Propionibacterium acnes (syn. Cutibacterium acnes) is the principal gram-positive anaerobe implicated in acne vulgaris through lipolysis, follicular obstruction, and pro-inflammatory cytokine induction. Rising antibiotic resistance among P. acnes strains necessitates plant-derived alternatives. This study evaluated the in vitro antibacterial activity and minimum inhibitory concentration (MIC) of Citrus aurantifolia lime peel ethanolic extract against P. acnes ATCC 6919 using the Kirby-Bauer disc diffusion method on Muller Hinton Agar (MHA). The extract was prepared by maceration with 96% ethanol from lime peels collected in Tulungagung, East Java, Indonesia. Fourteen concentrations (0.5–150 mg/mL) were tested in triplicate. The MIC was established at 1 mg/mL with an inhibition zone of 7.23 ± 0.15 mm. Inhibition zones increased proportionally with concentration, reaching 12.20 ± 0.10 mm at 150 mg/mL. Positive control (tetracycline 30 µg) produced 31.13 ± 0.38 mm. Antibacterial activity is attributed to multi-target mechanisms of flavonoids, tannins, alkaloids, and saponins acting on the cell wall, membrane, DNA, and virulence enzymes of P. acnes. These findings support the development of lime peel extract as a natural anti-acne ingredient.
Comparison of Continuous Percolation and Ultrasound-Assisted Extraction (UAE) Methods on Total Phenolic Content of 70% Ethanol Extract of Purslane (Portulaca oleracea L.) Aditya Sindu Sakti; Fransisca Dita Mayangsari; Sri Bintang Sahara Mahaputra Kusuma Negara; Elasari Dwi Pratiwi; Sandrawati
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/dxzsgc71

Abstract

Background: Portulaca oleracea L., commonly known as Krokot, is rich in phenolic compounds with notable pharmacological benefits. Optimizing extraction methods is critical to maximize its bioactive potential. Objective: This study aimed to compare the efficiency of Continuous Percolation (CP) and Ultrasound-Assisted Extraction (UAE) in obtaining total phenolic content (TPC) from 70% ethanol extract of P. oleracea. Methods: Dried powdered P. oleracea was subjected to CP and UAE using a 1:10 (w/v) plant-to-solvent ratio. Qualitative screening with FeCl₃ confirmed the presence of phenolics. TPC was quantified using the Folin–Ciocalteu method, expressed as mg gallic acid equivalent (GAE)/g extract. Statistical analysis included normality testing, Levene’s test, and the Mann–Whitney U test. Results: UAE yielded significantly higher TPC (420.04 ± 0.40 mg GAE/g) compared to CP (354.30 ± 0.00 mg GAE/g; p = 0.034), although CP produced a higher extract mass. Statistical results confirmed the superiority of UAE in selectively extracting phenolic constituents. Conclusion: UAE is more effective than CP in extracting phenolic compounds from P. oleracea, likely due to enhanced cavitation-induced mass transfer. This method is recommended for maximizing phenolic recovery in plant-based extractions, especially for thermolabile compounds.
Analisis Metode Perencanaan Dan Pengendalian Persediaan Obat Fast Moving Di Apotek Durikulon Sri Bintang Sahara Mahaputra Kusuma Negara; Lina Nurna Khumairo; Andini Suryani
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p1-8

Abstract

Drug availability is a crucial component of pharmaceutical services to ensure optimal patient care. Inadequate inventory planning and control, particularly for fast-moving drugs, often lead to stock shortages or surpluses that disrupt services and increase operational risks. This study aimed to analyze drug inventory planning and control for fast-moving items at Pharmacy X using consumption methods, Economic Order Quantity (EOQ), safety stock, and reorder point (ROP) approaches. This descriptive quantitative research utilized stock cards and observation sheets as instruments. Data on drug usage, stock availability, and procurement patterns from November 2024 to January 2025 were collected and analyzed. The results showed that applying these methods, such as for Renadinac tablets, produced an optimal procurement plan of 539 tablets, EOQ of 416 tablets, safety stock of 490 tablets, and a reorder point of 791 tablets. Proper planning and inventory control effectively ensured drug availability and optimized stock management.
Overview of Pharmaceutical Personnel's Knowledge of Good Compounding Practices in Community Pharmacies Sri Bintang Sahara Mahaputra Kusuma Negara; Devi Ristian Octavia; Asmaul Fitri Natasia; Andini Suryani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.660

Abstract

Compounding is a process of preparing medications tailored to the individual needs of patients by pharmaceutical personnel, due to the limited availability of ready-made drug formulations. Knowledge of drug compounding is essential for pharmaceutical personnel to ensure the availability of quality medications that are safe and effective in achieving therapeutic goals. This study aimed to assess the level of knowledge of pharmaceutical personnel regarding proper compounding practices in pharmacies in Lamongan. The study employed a descriptive design. Data were collected using a questionnaire distributed to pharmacies from February to April 2024. The sampling method used was simple random sampling with a total of 70 respondents. The data were processed and analyzed through editing, coding, scoring, and tabulating. The results showed that out of 70 respondents, the majority (58 respondents; 83%) had good knowledge, 7 respondents (10%) had moderate knowledge, and 5 respondents (7%) had poor knowledge. Knowledge of good compounding practice among pharmaceutical personnel indicated that the highest percentage of correct answers was in the category of compounding definition (97%), while the moderate level of answers was found in the category of compounding aspects (75%). Based on these findings, it can be concluded that pharmaceutical personnel working in pharmacies in Lamongan have, in general, good knowledge of compounding. Keywords: Pharmacy, Compounding, Knowledge, Pharmaceutical Personnel.