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Ety Apriliana
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Diabetes mellitus tipe 1: Literature Review Ringgi Tantra Setiawan; Ratna Dewi Puspita Sari; Andi Nafisah Tendri Adjeng; Ety Apriliana
Jurnal Kedokteran Universitas Lampung Vol 7, No 1 (2023): JURNAL KEDOKTERAN UNIVERSITAS LAMPUNG
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jkunila71%p

Abstract

Diabetes mellitus tipe 1 adalah penyakit kronis kedua yang paling umum dan gangguan endokrin-metabolik pada masa kanak-kanak yang ditandai dengan defisiensi insulin dan hiperglikemia yang dihasilkan. Ini semakin banyak didiagnosis pada anak-anak, karena spektrum skrining yang luas. Diperkirakan prevalensi antara 1,1 sampai 1,4/1000 anak di bawah usia 15 tahun. Diabetes mellitus tipe 1. membutuhkan penanganan yang hati-hati untuk menghindari komplikasi jangka panjang yang serius, termasuk penyakit jantung dan ginjal, stroke, dan kehilangan penglihatan. Saat ini, pengobatan “one-size-fts-all” untuk diabetes tipe 1 adalah terapi substitusi insulin eksogenik, namun pendekatan ini gagal mencapai kontrol glukosa darah yang optimal pada banyak individu. Situasi seperti itu dapat mempengaruhi kualitas hidup anak dan anggota keluarga. Faktor lingkungan dapat mempengaruhi faktor ini. Usia, jenis kelamin, jenis asuransi kesehatan memiliki hubungan yang signifikan secara statistik dengan kualitas hidup yang lebih baik. Pendidikan ibu, status perkawinan ibu, rejimen insulin dan kontrol glikemik mengubah kualitas hidup ibu-bayi. Usia rata-rata timbulnya penyakit adalah 8,8 tahun, memulai debutnya dengan ketoasidosis diabetik. Hemoglobin glikosilasi (HbA1c) adalah titik perubahan lainnya. Tingkat tinggi diperoleh dalam kepatuhan dan kualitas hidup. Kualitas hidup dikaitkan dengan penggunaan sistem pemantauan glukosa terus menerus untuk menghindari hipoglikemia yang tidak terlalu parah dan komplikasi ginjal. Menghadapi situasi seperti itu, tujuannya adalah untuk melakukan tinjauan literatur tentang subjek untuk menilai dampak diabetes tipe 1 dan akibatnya pada kehidupan anak.Kata Kunci: DM Tipe 1, Kompikasi, Tatalaksana
Faktor-faktor yang Mempengaruhi Prolaps Organ Panggul di RSUD DR. H. Abdul Moeloek Provinsi Lampung Periode 1 Januari 2014 – 31 Desember 2018 Fiana Deswita; Ratna Dewi Puspita Sari; Ety Apriliana; Nurul Islamy
MAJORITY Vol 10 No 2 (2021): MAJORITY
Publisher : Majority

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Abstract

Pelvic organ prolapse (POP) is a condition that affects a woman's quality of life. Pelvic organ prolapse can include uterine prolapse, cystocele and rectocele. POP occurs due to weakness of the muscles, ligaments and fascia that support the pelvic organs. This condition can be influenced by factors such as age, parity, menopause, body mass index and occupation. This study aims to determine the relationship of these factors to the incidence of POP. The study is an observational analytic with cross sectional approach, using secondary data from the medical records of gynecological patients at H. Abdul Moeloek Hospital in the period 1 January 2014 to 31 December 2018 with a total sampling technique. Then univariate and bivariate analyzes were performed using the chi-square test. The incidence of POP in the period of 1 January 2014 to 31 December 2018 in the H. Abdul Moeloek Hospital was 33 cases. Factors that had a relationship with the highest risk sequence are parity (p = 0.000; OR 7,959), age (p = 0.002; OR 7,250), menopause (p = 0.014; OR 5.019), body mass index (p = 0.036; OR 3.297) and type of work (p = 0.036; OR 3.297).All factors studied is parity, age, menopause, body mass index and type of work were associated with the incidence of pelvic organ prolapse in patients at H. Abdul Moeloek Hospital, Lampung Province January 2014 to 31 December 2018
Pola Bakteri Ulkus Diabetikum Pada Penderita Diabetes Melitus di RSUD Dr. H. Abdul Moeloek Haula Rizqiyah; Tri Umiana Soleha; Rizki Hanriko; Ety Apriliana
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

Diabetes mellitus is a term for heterogeneous of metabolism disturbances for which the main finding is chronic hyperglycaemia. In diabetes mellitus, elevated glycaemic levels increases the risk of microvascular and macrovascular complications. These increase risk of further complications such as peripheral neuropathy which can cause foot ulcerations. Diabetic extremity ulcers develop in approximately 15% of people with diabetes and are a leading cause of hospitalization and amputation among such patient. Diabetic foot ulcer infection followed by amputation contribute dramatically not only to the morbidity among persons with diabetes, but are also associated with severe clinical depression and increased mortality rates. The aim of the study was to determine the bacterial profile of diabetic foot ulcer in RSUD Dr. H. Abdul Moeloek. This study was a descriptive study using a cross sectional study. Sampling was conducted at RSUD Dr. H. Abdul Moeloek and examined in Microbiology-Parasitology Laboratorium in Medicine Faculty of Lampung University. The diabetic foot ulcer swab was taken to identified the bacteria. Bacteria were isolated on nutrient agar, blood agar, Mc Conkey agar, and identified using Gram staining and biochemical test. In the 21 diabetic foot patients, 16 were males (76.2%) and 5 were females (23.8%) and grade-II Wagner’s ulcers were predominant, which is deep ulcer without bony involvement or abscess. In the diabetic foot ulcers cases, 85.7% cases had monomicrobial infections while 14.3% cases had mixed bacterial infection. Gram-positive bacteria accounted for 62.5%. Staphylococcus aureus was the most frequent microorganism yielded (58%). Gram-negative rods accounted for 37.5%. Escherichia coli was the most predominant gram-negative organism (17%). Staphylococcus aureus, Staphylococcus epidermidis, Citrobacter freundii, Escherichia coli, and Proteus mirabilis were found in diabetic foot infections in the present study.
Perbandingan Tingkat Stres pada Mahasiswa Tingkat I, II dan III Fakultas Kedokteran Universitas Lampung Nabila Casogi Adryana; Oktafany; Ety Apriliana; Dwita Oktaria
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

Stress is a condition of physical, emotional, mental and spiritual disability in response to a threat causing physical health problems. College students are the individuals who are prepared to be globally competitive as human resources. The aim of the study is to determine the comparison of stress level in the first, second, and third year students of Medical Faculty of University of Lampung.This study was a analytical descriptive study using cross sectional design and proportionate stratified random sampling as sampling method. Questionnaires was used as measuring instrument. The data was analyzed using one-way ANOVA.The data were assessed in total 312 subjects as respondent, and accounted of 102 in the first, 100 in the second, and 98 in the third year. A percentage of 76.5% of moderate stress and 23.5% of severe stress were obtained from the first year ofstudents. The subjects of the second year were 82% of moderate stress and 18% of severe stress.The subjects of 98 of the third year own 65.3% of moderate stress and 34.7% of severe stress. One-way ANNOVA test results showed p value of 0,001. There was a comparison of stress levelin the first, second, and third yearstudents of Medical Faculty of University of Lampung. This study showed a comparison of stress level in the first, second, and third year students of Medical Faculty of University of Lampung.
Peningkatan Risiko infeksi Multi Drugs Resitant Tuberculosis (MDR-TB) pada Penderita Human Immunodeficiency Virus (HIV) Dwiki Wijaya Rahman; Ety Apriliana
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

HIV infection is the biggest challenge for tuberculosis control efforts. People with HIV will have a greater potential to be infected with tuberculosis as an opportunistic disease or to aggravate existing tuberculosis into active tuberculosis. MDR-TB is tuberculosis that is resistant to at least 2 types of anti-tuberculosis drugs (OAT). HIV sufferers will be more at risk of experiencing MDR-TB coinfection due to several reasons, one of which is HIV infection which can cause OAT malabsorption, such as rifampin and ethambutol, too much treatment causes patient non-compliance with treatment, and the possibility of HIV and MDR-TB sufferers who are in areas of the same prevalence, such as in hospitals and densely populated environments, cause the transmission of MDR-TB is more susceptible to HIV sufferers due to a weakened immune system.
Faktor-Faktor Internal Yang Berperan Dalam Keberhasilan Terapi Pasien Terhadap Penyakit Morbus Hansen Di Kota Bandar Lampung Siti Zahnia; Tri Umiana Soleha; Ety Apriliana
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

Morbus Hansen (MH) is a chronicinfectiousdisease caused by Mycobacterium leprae. Morbus Hansen's disease is a national public health problem in Indonesia. The cure rate in Lampung in 2014 is about 83.3% for PB and 60.1% for MB. The cure rate has not yet reached the target release from treatment, which is >90%. Low achievement of MH cure rate can be caused by patients who’re not regularly taking the medication. The lack of MH cure rate can be caused byseveralfactors, which are externalamd internal factors. This study aimed to determine the internal factors that associated with therapy success of Morbus Hansen's disease in Bandar Lampung. This study is an observational study with cross sectional design.The sample in this study isMH patients who take medication to Puskesmas in Bandar Lampung region, about 42 patients. Data then analyzed using chi-square test. The results showed that out of 42 respondents, the success of MH therapy is bigger on the child's age, female gender, higher education, not working, medication adherence, good knowledge and good socio-economic. From the bivariate analysis, it’s known that there is influence of age (p=0,017), knowledge (p=0,030) and socio-economic on the successful of therapy (p=0.002), while gender, education and employment do not affect the success of the therapy (p = 0.190; p = 0.064; p = 0.355). From six internal factors analyzed in this studythere are only age, level of knowledge and socio-economic thatassociated to the successful therapyof patients withMorbus Hansen's disease.
Identifikasi Mikroorganisme Yang Ditemukan Di Dalam Cairan Pembersih Lensa Kontak Pada Mahasiswa Fakultas Kedokteran Denny Habiburrrohman; Tri Umiana Soleha; Ety Apriliana; Dwita Oktaria
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

The development and use of contact lenses is increasing rapidly, both in developed and developing countries. In line with that many contact lens users are one of the names of infections in the eye. One of the causes is contamination of contact lens solution. To identify the types of microorganisms found in contact lens solutions in students of the Faculty of Medicine, University of Lampung in 2018. This study used a descriptive observational research type. The study was conducted at the Faculty of Medicine, University of Lampung in June 2018. Samples were contact lens solution, with a total sample of 30 samples. The sample was taken to the Laboratory of Microbiology, Faculty of Medicine, University of Lampung. Samples were identified by bacterial culture, gram staining and biochemical tests. Identification of B. subtilis (22%), Pseudomonas aeruginosa (11%), Staphylococcus aureus (8%), Serratia sp (7%), Klebsiella sp (7%), E.coli (2%) . Of the 60 samples studied, it was found that there were no bacterial growths in 26 samples (43%), and there was bacterial growth in 34 samples (57%)
Co-Authors Ade Yonata Agustyas Tjiptaningrum Alexander Dicky Denny Habiburrrohman Dwiki WIjaya Rahman Dwita Oktaria Echa Putri Anjani Efrida Warganegara Fiana Deswita Ghina Nisrina Nurfatin Haula Rizqiyah Liana Sidharti Mallarangeng, Andi Nafisah Tendri Adjeng Merry Indah Sari Meta Gapila Muhammad Ricky Ramadhian Muhammad Yusran Mukhlis Imanto Nabila Casogi Adryana Novita Carolia Nurul Islamy Oktafany Putu Urvasi Ari Utami Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Reffilia Irfa Retno Julianingrum Rika Lisiswanti Rindu Bunga Putri Ringgi Tantra Setiawan Rizki Hanriko Siti Zahnia Tri Umiana Soleha Wildan Kautsar Irawan