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Journal : Medula

Analysis Of Antihypertensive Use In Pregnant Women With Severe Preeclampsia At Inpatient Ward of Dr.H. Abdoel Moeloek Hospital Bandar Lampung Period January-September 2016 Reffilia Irfa; Rasmi Zakiah Oktarlina; Ety Apriliana; Tri Umiana Soleha
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.9

Abstract

Hypertension in pregnancy plays a major role in maternal and perinatal morbidity and mortality. Half to two-thirds of women with hypertension are diagnosed with preeclampsia and even eclampsia. One way to overcome hypertension is by antihypertensive pharmacological therapy. This study aims to analyze the use of antihypertensives in pregnant women with severe preeclampsia in the inpatient installation of RSUD Dr. H. Abdoel Moeloek for the period January-September 2016. Researchers used a cross-sectional approach and secondary data collection through 96 medical records of pregnant women with severe preeclampsia given antihypertensive drugs at RSUD Dr. H. Abdoel Moeloek during the period January-September 2016 based on dose accuracy, the accuracy of indication and accuracy of frequency is in accordance with the 2015 Queensland Health (Hypertensive Disorders of Pregnancy) and BNF (British National Formulary) 61 in 2011, with an exact indication of 83.3 %, the dose accuracy is 100%, and the frequency is 100%.
Hubungan antara Lingkungan Belajar dengan Pendekatan Belajar Mahasiswa Tahun Pertama Fakultas Kedokteran Universitas Lampung Echa Putri Anjani; Merry Indah Sari; Ety Apriliana
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.78

Abstract

The learning environment in medical education cast of physical, non-physical/social context in which students study. The learning environment creates an atmosphere of learning that influences student behaviors and efforts that are visible from the way they choose a learning approach that ultimately affects learning outcomes. The learning approach consists of a deep approach and a surface approach. The study aim to find the relationship between the perception of learning environment and learning approach among first year student at the Medical Faculty Lampung University. This is a cross sectional study with sample of 214 first year medical students. Data were collected using Dundee Ready Educational Environment Measure (DREEM) and Revised Two-Factor Study Process Questionnaire (R-SPQ-2F). There are 87 students (40,7%) have excellent perception to learning environment and 127 students (59,3%) have good perception. There were 202 students (94.4%) using deep approach and 12 students (5.6%) using surface approach. Students have excellent perceptions of the learning environment with an deep approach of 84 students (96.6%) and using a surface approach of 3 students (3.4%). Students who have a good perception of the learning environment with deep approach of 118 students (92.9%) and using the surface approach of 9 students (7.1%). The data was statistically tested using Fisher exact test and p value is 0,368 (>0,05). The result there is no significant relationship between the perception of learning environment and learning approach among first year student at the Medical Faculty Lampung University.
Uji Daya Hambat Solutio Belerang Terhadap Pertumbuhan Bakteri Propionibacterium acnes Secara In Vitro Rindu Bunga Putri; Novita Carolia; Ety Apriliana
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.97

Abstract

Acne Vulgaris is an inflammation of the polysebaseal follicles indicated by the appearance of blackheads, papules, pustules, cysts and nodules, which often occur mainly in the chest (15%), face (99%), and back (60%). In Indonesia around 95-100% of men and 83-85% of women aged 16-17 years suffer from acne. One of the microorganisms that cause acne vulgaris is Propionibacterium acnes bacteria which is a normal flora on the skin. In treatment, acne vulgaris wide-spectrum antibiotics have been commonly used as a treatment for acne, as the time goes by, it has been found there are increasement of Propionibacterium acnes resistance to antibiotics like erythromycin, clindamycin, and tetracycline. Sulfur has been widely used in anti-acne products which have an antibacterial function and can inhibit the growth of Propionibacterium acne as a cause of acne. This study aims to test sulfur solutio with concentrations that are often used in anti-acne products, namely 2-10% in inhibiting P.acne bacteria. This type of research is an experimental laboratory with a well method. Solutio sulfur is divided by various concentrations of 10%, 8%, 6%, 4%, and 2%, with K (-) is distilled water, and K (+) is a clindamycin gel antibiotic. The data is based on the results of the measurement of the inhibition zone formed and tested with One Way Anova. The results of this study indicate the diameter of the inhibition zone formed sequentially, namely: 12.70 mm, 10.55 mm, 7.70 mm, 5.80 mm, 4.67 mm, positive control of 30,075 mm and negative concentration of 0 mm (p value = 0,001). There is an antibacterial effect of sulfur solutio with a concentration of 10%, 8%, 6%, 4% and 2% against Propionibacterium acnes bacteria.
PENGARUH ALGAE MERAH (EUCHEUMA SPINOSUM) TERHADAP INFEKSI ESCHERICHIA COLI Putu Urvasi Ari Utami; Ety Apriliana; Rika Lisiswanti; Liana Sidharti
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.651

Abstract

Bacteria can contribute to the development of diarrheal disease through direct contact with those who have the condition, consumption of food and drink contaminated with feces, or both. In addition, water, food sanitation, family latrines are the main causes of diarrheal disease. Among the causative bacteria, Escherichia coli is the most common pathogen for diarrhea in children in developing countries and an associated entero-pathogen of emerging antimicrobial resistance in developed countries. Reports of increased antibacterial resistance have become a challenge in handling diarrhea cases. Eucheuma spinosum is a species of red algae which is a marine organism that has been screened for phytochemicals and found to contain active substances such as flavonoids, triterpenoids, alkaloids, and ascorbic acid. Phenol compounds and their derivatives (flavonoids) are predicted to be compounds in E. spinosum that have the potential to inhibit E. coli bacteria by damaging the bacterial cytoplasmic wall.
Hipotensi Intradialitik pada Pasien Gagal Ginjal Kronik Ghina Nisrina Nurfatin; Ade Yonata; Ety Apriliana
Medula Vol 13 No 3 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i3.663

Abstract

Chronic renal failure is a disease defined as kidney damage or an estimated glomerular filtration rate (eGFR) of less than 60 ml/min/1.73 m2 and persisting for 3 months or more. Chronic kidney disease is irreversible and often requires hemodialysis as a treatment. As many as 10% of people in the world have chronic kidney failure. More than 2 million people receive therapy with dialysis or hemodialysis and kidney transplants. Hemodialysis is a kidney replacement therapy that is carried out by flowing the patient's blood into a dialyser. This therapy is considered effective in reducing mortality due to chronic kidney failure. However, various complications can also be caused by the use of this hemodialysis device, one of which is intradialytic hypotension. Intradialysis hypotension will cause a decrease in tissue perfusion. This decrease in tissue perfusion will lead to reduced blood supply to the periphery, heart, kidneys, and even the brain. Preventive measures are the best method of avoiding intradialytic hypotension. This complication must be avoided and managed immediately because it can cause damage to vital organs which can be fatal to the body.