Dr. Soedirman Kebumen Regional General Hospital has implemented PACS to replace traditional film, but limitations in IT infrastructure, RME integration, and human resource readiness require an integrated implementation model that combines cloud-hybrid, DICOM/HL7 with SSO, continuous training, and managerial support. To evaluate the implementation of the PACS system in the Radiology Department of Dr. Soedirman General Hospital in Kebumen and to analyze the factors that support and hinder the effectiveness of the PACS system in improving the quality of radiology services. The research used a qualitative approach with an interactive model. Data collection was conducted through in-depth interviews, Focus Group Discussions (FGD), direct observation, and documentation. The data obtained were analyzed using ATLAS.ti software to explain the PACS implementation and its impact on the effectiveness of radiology services. The PACS implementation improved the quality of radiology services by accelerating access to medical images and enhancing workflow efficiency. Some challenges, such as system downtime, integration with other systems, and technical limitations, need to be addressed. Integration of artificial intelligence (AI) and telemedicine technologies needs to be enhanced to achieve optimal radiology services. Factors supporting successful implementation include the adoption of advanced technologies (cloud computing and AI), adequate infrastructure, technical support from the IT team, and strong managerial commitment. Barriers to success include imperfect system integration, power outages, downtime, storage capacity limitations, and a shortage of trained human resources. Proposed implementation models include improving PACS system infrastructure, developing ongoing training for staff, improving PACS system integration with other hospital systems, and improving interdepartmental communication to streamline workflows and reduce obstacles in the diagnostic process.