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Journal : ANJANI Journal (Medical Science

THE EFFECT OF DRIED RED GINGER EXTRACT POWDER (Zingiber officinale var. rubrum) ON THE LDL, TRIGLYCERIDES and HDL Oktoviani Oktoviani; Ellen Maidia Djatmiko; Hilda Taurina; Riana Versita
ANJANI Journal (Medical Science & Healthcare Studies) Vol 1, No 2 (2021)
Publisher : Perkumpulan Dosen Muda Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (439.088 KB) | DOI: 10.37638/anjani.v1i2.454

Abstract

Tradisional medicine is a part of Indonesian medicine cukture. As ginger is known to affect blood lipid profile, especially red ginger (Zingiber officinale var. rubrum) with a higher volatile oil content than other types of ginger. Meanwhile, dyslipidemia is a state of abnormal blood lipid profile levels. This research was conducted at RSUD dr. M. Yunus Bengkulu in 2014. Subjects were dyslipidemia with diabetes mellitus type 2 patients in age range 30-60 years. The total subjects in this study were 10 patients with simple random sampling grouping method. Then thay were devided into control group and treatment group. Neither group received standard drug therapy. The dried red ginger powder was only given to the treatment group at a dose of 3 grams per day for one month.. Both groups examined the LDL (Low Density Lipoprotein), trigliseride and HDL (High Density Lipoprotein) levels before and after the study. Changes to LDL, trigliseride and HDL levels were tested by independent sample test with a significance value of p 0.05. From the research that has been done is known that the dried red ginger powder not significantly affect LDL, trigliserida and HDL (p LDL=0,261; p Trigliserida=0,966; p HDL= 0,175). Based on the statistical analysis, it is known that the dried red ginger powder not significantly affect LDL, trigliserida and HDL. Descriptive analysis showed a decrease in triglyceride levels. Deskriptive analysis shows that the dried red ginger powder can inhibit the incerase to LDL, can reduce triglyceride and inhibit the decrease to HDL.
The Relationship between Demographic Characteristics and Patient Compliance Undergoing Tuberculosis (Tbc) Treatment at the Bintuhan Health Center, Kaur Regency, Bengkulu Province Riana Versita; Nova Yustisia; Suci Rachmawati; Cendy Felya Nengsih
ANJANI Journal (Medical Science & Healthcare Studies) Vol 1, No 2 (2021)
Publisher : Perkumpulan Dosen Muda Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37638/anjani.v1i2.444

Abstract

Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis bacteria. Adherence to long-term TB treatment is key to controlling tuberculosis. Non-compliance is a serious problem that often occurs which causes the therapeutic goals not to be achieved. This study aims to measure the level of patient compliance with the use of anti-TB drugs. This research was conducted at the Bintuhan Health Center, Kaur Regency. This research is observational by using descriptive method and total sampling technique . The data collection on characteristic and patients compliance was made through  a questionnaire. The data obtained were recapitulated and processed using the Chie Square SPSS 24 method in tabular form and presented in percentage form.The results showed that the relationship between gender P-value = 0.01, occupation P value = 0.065, education level p value = 0.330, on the level of compliance, where gender has a relationship with compliance p = 0.01 0.05 Ho rejected and Ha accepted, while the relationship between work p = 0.065 and education p = 0.330 on compliance tended to have no effect.
PHYTOCHEMICAL SCREENING OF SECONDARY METABOLID ETHYL ACETATE EXTRACT DURIAN RIND (Durio zibethinus Murr) COLLECTED FROM CENTRAL BENGKULU REGENCY” riana versita
ANJANI Journal (Medical Science & Healthcare Studies) Vol 3, No 1 (2023)
Publisher : Perkumpulan Dosen Muda Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37638/anjani.v3i1.700

Abstract

Introduction: Durian (Durio zibenthinus Murr) is one of the genetic resources (SDGs) of the local plant of Bengkulu Province which has quite high economic value. The durian plant is a tropical plant in Southeast Asia. Methods: This study used laboratory tests to determine the secondary metabolites present in the rind of Durian (Durio zibenthinus Murr) during the phytochemical screening process using ethyl acetate solvent. Result and Discussion: Alkaloid compounds are characterized by changes in color in the sample after being dripped with Dragendroff, Mayer and Wagner reagents. In addition, the ethyl acetate extract of Durian peel (Durio zibenthinus Murr) also contains triterpenoid compounds, flavonoids and tannins which can be used in herbal medicine. However, it does not contain steroid compounds, saponins because at the time of the study there was no color change such as the color of the greenish-blue ring for steroids but rather a bluish-green color which can be seen to contain steroid compounds. Conclusion: from this study, the components contained in Durian peel (Durio zibenthinus Murr) were extracted with ethyl acetate solvent, namely alkaloids, flavonoids, triterpenoids and tannins.
Formulasi Sediaan Sabun Cair Mengandung Ekstrak Bunga Telang (Clitoria Ternatea L.) Dewi, Ella Junita; Sanora, Sindi; Ikhsan, Ikhsan; Versita, Riana
ANJANI Journal (Medical Science & Healthcare Studies) Vol 3, No 2 (2023)
Publisher : Perkumpulan Dosen Muda Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37638/anjani.v3i2.812

Abstract

ABSTRAKPendahuluan: Salah satu kosmetik pembersih kulit yang selalu dibutuhkan saat ini adalah sabun mandi. Kulit sangat membutuhkan antioksidan untuk menangkal paparan radikal bebas. Bunga Telang (Clitoria ternatea.L) memiliki aktivitas sebagai antioksidan. Bunga telang (Clitoria ternatea.L) diambil dari sekitaran kota Bengkulu dan telah dilakukan verifikasi untuk menunjukkan bahwa tanaman yang digunakan benar jenis atau spesies tanamannya. Metode: Penelitian ini menggunakan metode eksperimental yang bertujuan untuk membuat inovasi formula sediaan sabun cair dari ekstrak bunga telang (Clitoria ternatea L.) dengan variasi Na-CMC 0,5% sebagai F0 tanpa menggunakan ekstrak bunga telang (Clitoria ternatea.L) , dan Na-CMC 1%, 1,5%, 2% dengan menggunakan ekstrak bunga telang (Clitoria ternatea.L) 5% yang selanjutnya dilakukan uji organoleptis, uji homogenitas, penentuan pH sediaan, uji viskositas, uji tinggi busa dan kestabilan busa, uji stabilitas sediaan, uji waktu terbilaskan, uji daya bersih sabun, uji iritasi, dan uji hedonik. Hasil dan Pembahasan: Hasil menunjukkan bahwa sabun cair yang diformulasikan dengan ekstrak bunga telang berwarna lebih gelap, dengan aroma yang khas, dan berbentuk cairan homogen dengan kekentalan yang berbeda-beda dengan viskositas antara 500 cP-3500 cP, dan pH sediaan 8-9, dengan waktu terbilaskan rata-rata 13 detik, dan memiliki kemampuan membersihkan noda yang tidak menimbulkan iritasi. Kesimpulan: Formula terbaik berdasarkan hasil evaluasi adalah formula dengan Na-CMC 1,5% dan ekstrak bunga telang 5% dengan ph 8,43 dan viskositas 1201,09 cP. ABSTRACTIntoduction: One of the skin cleansing cosmetics that is always needed today is bath soap. The skin desperately needs antioxidants to ward off exposure to free radicals. Telang flower (Clitoria ternatea.L) has activity as an antioxidant. Butterfly pea flower (Clitoria ternatea.L) was taken from around the city of Bengkulu and has been verified to show that the plant used is the correct type or species of plant Method: This study used an experimental method with the aim of innovating a liquid soap formula made from butterfly pea flower (Clitoria ternatea L.) extract with 0.5% Na-CMC as F0 without using butterfly pea flower (Clitoria ternatea.L) extract, and Na-CMC 1%, 1, 5%, 2% using 5% butterfly pea flower (Clitoria ternatea.L) extract which is then carried out by organoleptic test, homogeneity test, determination of preparation pH, viscosity test, foam height test and foam stability test, preparation stability test, rinsing time test, soap cleaning power test, irritation test , and hedonic test. Result and Discussion:  The results showed that the liquid soap formulated with butterfly pea (Clitoria ternatea.L) extract was darker in color, had a distinctive aroma, and was in the form of a homogeneous liquid with different viscosities with a viscosity between 500 cP-3500 cP, and a preparation pH of 8-9, with an average rinse time. -13 seconds on average, and has non-irritating stain-clearing capabilities.Conclusion: The best formula based on the evaluation results is the formula with 1.5% Na-CMC and 5% butterfly pea flower (Clitoria ternatea.L) extract with a pH of 8.43 and a viscosity of 1201.09 cP.
Skrining Fitokimia Metabolid Sekunder Ektrak Etil Asetat Kulit Buah Durian (durio zibethinus murr) Diambil Dari Kabupaten Bengkulu Tengah Versita, Riana; Ekuansah, Muhammad; Oktoviani, Oktoviani
ANJANI Journal (Medical Science & Healthcare Studies) Vol 3, No 2 (2023)
Publisher : Perkumpulan Dosen Muda Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37638/anjani.v3i2.696

Abstract

Pendahuluan: Durian (Durio zibenthinus Murr) merupakan salah satu sumber daya genetik (SDG) tanaman lokal Provinsi Bengkulu yang memiliki nilai ekonomis yang cukup tinggi. Tanaman durian adalah tumbuhan tropis Asia Tenggara yang hanya dimanfaatkan buah dan batang pohonya saja sedangkan kulit buah durian hanya sebagai limbah” Metode: Penelitian ini menggunakan pemeriksaan di laboratorium yang bertujuan untuk mengetahui metabolit sekunder yang terdapat pada kulit buah Durian (Durio zibenthinus Murr) dalam proses skrining fitokimia menggunakan pelarut etil asetat “Hasil dan Pembahasan: Hasil ekstrak etil asetat kulit buah Durian (Durio zibenthinus Murr) mengandung senyawa alkaloid ditandai dengan berubahnya warna pada sampel setelah ditetesi dengan reagen dragendroff, mayer dan wagner. Selain itu ekstrak etil asetat kulit Durian (Durio zibenthinus Murr)  juga mengandung senyawa triterpenoid, flavonoid dan tanin yang dapat dimanfaatkan didalam pengobatan herbal seperti antikanker.” Namun tidak mengandung senyawa steroid, saponin karena pada saat penelitian tidak terjadi perubahan warna seperti warna cincin biru kehijauan untuk steroid melainkan berwarna hijau kebiruan yang dapat diketahui bahwasanya mengandung senyawa steroid. “Kesimpulan: dari penelitian ini adalah komponen yang terkandung dalam kulit Durian (Durio zibenthinus Murr)  diekstrak dengan pelarut etil asetat yaitu alkaloid, flavonoid, triterpenoid dan tanin. ABSTRACTIntroduction: Durian (Durio zibenthinus Murr) is one of the genetic resources (SDGs) of the local plant of Bengkulu Province which has quite high economic value. The durian plant is a tropical plant in Southeast Asia. Methods: This study used laboratory tests to determine the secondary metabolites present in the rind of Durian (Durio zibenthinus Murr) during the phytochemical screening process using ethyl acetate solvent. Result and Discussion: Alkaloid compounds are characterized by changes in color in the sample after being dripped with Dragendroff, Mayer and Wagner reagents. In addition, the ethyl acetate extract of Durian peel (Durio zibenthinus Murr) also contains triterpenoid compounds, flavonoids and tannins which can be used in herbal medicine. However, it does not contain steroid compounds, saponins because at the time of the study there was no color change such as the color of the greenish-blue ring for steroids but rather a bluish-green color which can be seen to contain steroid compounds. Conclusion: from this study, the components contained in Durian peel (Durio zibenthinus Murr) were extracted with ethyl acetate solvent, namely alkaloids, flavonoids, triterpenoids and tannins.