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Anti-inflammatory effectiveness of Cymbopogon citratus DC. Staff in Na CMC gel preparation Indrawati, Teti; Rahman Hakim, Zainur; Rahayu, Renu; St Djuhariah, Yayah
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1668

Abstract

Cymbopogon citratus DC. Stapf contains saponins, tannins, and flavonoids. Traditionally, tea from lemongrass leaves is useful as an anti-inflammatory, anti-malarial, anti-mutagenic, anti-mycobacterial, antioxidant, hypoglycemic, and neurobehavioral. A study has been conducted to formulate an anti-inflammatory gel preparation from C. citratus extract. The study was conducted by macerated a C. citratus leafs using 70% ethanol, then evaporated in a rotary evaporator at a temperature of 40 ºC until viscouse extract obtained and evaluated. The anti-inflammatory gel was prepared using Na CMC 6%, with the concentration of C. citratus extract 6%, 8%, and 10%. The resulting gel preparation was evaluated for its physical and chemical properties and then tested for its anti-inflammatory effects using male mice (Mus musculus L.). Flavonoids, alkaloids, tannins, and saponins are found in this C. citratus extract. The characteristics of the C. citratus extract gel made were, brown and dark brown, had a distinctive C. citratus odor, semi-solid, and homogeneous, had a pH of 5.54–5.62, a viscosity value between 57000-73000 cP, had pseudoplastic flow properties, a specific gravity between 1.055-1.078 g/cm3, had an adhesiveness of 231-252 seconds, and a spreadability of 3490.11-3021.20 mm2. The gel contained 10% of C. citratus extract, indicating the highest anti-inflammatory effect, with a decrease in edema diameter of 67.79% in the legs of male mice. 
Analisis Perspektif Maslahah terhadap Keputusan Pemerintah terkait Pelegalan Alat Kontrasepsi di Indonesia Wathoni, M. Naufal Addil; Mutawali, Muhammad; Indrawati, Teti
Tasyri' : Journal of Islamic Law Vol. 4 No. 2 (2025): Tasyri'
Publisher : STAINI Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53038/tsyr.v4i2.151

Abstract

This study analyzes government policies related to the legalization of contraceptives through the maslahah theory, where the government recently legalized contraceptives in Indonesia for school teenagers in Indonesia. This theory examines how the benefits and harms are contained in government policies related to the legalization of contraceptives in Indonesia. As we know that contraceptives function as a means of preventing pregnancy among married couples who hold the concept of family planning. This study uses a literature study approach, where data and documentation are taken from books, articles, journals, research report notes from previous researchers. This study also uses a normative legal research method with a literature study approach. The main sources include classical and contemporary fiqh books, journal articles, and legal reports. This study identifies that this legalization has two dimensions of maslahah: al-mursalah for married couples, meaning that contraceptives for married couples have benefits, namely as a means of preventing pregnancy and al-mulghah for unmarried adolescent users, meaning that if an unmarried couple uses contraceptives to have sex like a husband and wife, it is still counted as an act of adultery. This research offers a new perspective in understanding the relationship between public policy and maqasid sharia.