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All Journal Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN INDONESIAN JOURNAL OF PHARMACY Molecular and Cellular Biomedical Sciences (MCBS) JSFK (Jurnal Sains Farmasi & Klinis) JPK: Jurnal Proteksi Kesehatan Literacy: Jurnal Pendidikan Ekonomi Jurnal Kajian Islam dan Sosial Keagamaan Jurnal Sains Farmasi dan Kesehatan Jurnal Vokasi Keperawatan (JVK) Andalasian Livestock Jurnal Bioteknologi & Biosains Indonesia (JBBI)
Marlina .
Fakultas Farmasi Universitas Andalas
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Literatur Review: Prospects of Stem Cell Secretomes for the Treatment of Hair Loss/Alopecia Nella Novita; Marlina Marlina; Regina Andayani
JURNAL PROTEKSI KESEHATAN Vol 12 No 1 (2023): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v12i1.666

Abstract

The goal of this literature review is to find out the role of MSC in stimulating hair growth, particularly in people who suffer from hair loss/alopecia. Literature reviews were conducted using an electronic database such as Researchgate, PubMed, GoogleScholar, and ScienceDirect. MSC secretome for hair growth, secretome for hair growth, ADSC-Exosome for hair growth, ADSC-CM for alopecia, secretome conditioned medium for baldness, and formulation of hair tonic preparations to stimulate hair growth were the keywords used. From these keywords, 13 relevant research articles were found, 11 of which used patients with alopecia as research subjects in randomized clinical trials to examine hair growth. MSC therapy for alopecia has been shown to stimulate hair growth, density, and thickness.
Aplikasi Agarosa sebagai Matriks Kultur 3d pada Sel Kanker Paru Line A549 Suci Rahmawati; Adek Zamrud Adnan; Muhammad Taher; Marlina Marlina
Jurnal Vokasi Keperawatan (JVK) Vol. 2 No. 2 (2019): DESEMBER
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/jvk.v2i2.10690

Abstract

Agarosa merupakan salah satu biopolimer yang sering digunakan dalam bidang bioteknologi, diantaranya sebagai matriks pada kultur sel. Penelitian ini bertujuan untuk mengaplikasikan agarosa hasil isolasi dari tepung agar sebagai matriks kultur 3D pada sel kanker paru line A549. Hasil isolasi diperoleh Agarosa 1 (A1) dan Agarosa 2 (A2) hasil pemurnian dari A1. A1 dan A2 dengan konsentrasi 5% diaplikasikan sebagai matriks kultur 3D di dalam well plate kultur sel kanker paru line A549 dengan densitas 107, sebagai kontrol pertumbuhan digunakan kultur 2D sel (well plate tanpa matriks) dan kontrol positif kultur 3D sel pada matriks agarosa Top Vision®. Viabilitas sel diamati pada hari ke 2, 4 dan 6 menggunakan pewarna trypan blue. Proliferasi sel diamati pada hari ke 6 menggunakan reagen MTT. Hasil uji viabilitas terlihat agregat sel 3D pada matriks agarosa yang viable dan tidak menyerap warna trypan blue. Viabilitas sel dibuktikan dengan uji proliferasi dan diperoleh nilai rata-rata absorban pada kultur 2D, kultur 3D matriks kontrol, A1 dan A2 masing-masingnya 2.03; 1.21; 0.96 dan 1.22. Proliferasi kultur 2D lebih baik dari 3D, akan tetapi proliferasi kultur 3D pada matriks A2 lebih baik dari matriks kontrol. Pada penelitian ini dapat disimpulkan bahwa agarosa dapat diaplikasikan sebagai matriks kultur 3D sel
Swiftlet Bird's Nest (Collocalia fuciphaga) from West Sumatra as a Functional Food and Its Nutritional Content Aditya Willy Putra; Endang Purwati; Marlina
Andalasian Livestock Vol. 1 No. 1 (2024): ALive
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/alive.v1.n1.p9-17.2024

Abstract

Functional foods contain biologically active components and compounds that have physiological effects on the human body, such as promoting health and decreasing the risk of sickness. The swiftlet, which belongs to the Collocalini family, is an insect-eating bird that migrates across the Indian Ocean, Southeast Asia, and northern Australia to the Pacific Ocean. Swiftlet bird's nests (SBN) contain protein, fats, carbohydrates, iron, calcium, phosphorus, inorganic salts, fiber, and water. The objective of this study is to determine the nutritional content of swiftlet bird nests in different regions of West Sumatra. Samples of swiftlet bird's nests (SBN) were collected from Padang City (PD), Bukittinggi City (BK), and Pesisir Selatan Regency (PS). Nutritional content was analyzed using proximate methods, including moisture, protein, and fat, and the nitrite concentration was measured using UV-Vis spectrophotometry. The study found that SBN in West Sumatra contains 47.65–50.55% protein, 1.48–2.47% fat, 21.77–22.77% water, and 24.75–32.72 ppm nitrite. The results indicate that the nutritional content varies among the samples, and the protein content found in SBN is higher, making it suitable for use as a functional food. Additionally, SBN has many health benefits and biological activities, such as mitogenic response and cell growth, enhanced immunity, and improved bone strength.
ANALYSIS OF INTERLEUKIN-10 LEVELS IN MESENCHYMAL STEM CELL SECRETOME CREAM WITH ELISA METHOD Vika Amelia; Marlina; Ikhwan Resmala Sudji
Jurnal Bioteknologi dan Biosains Indonesia Vol. 10 No. 2 (2023)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mesenchymal Stem Cells (MSC) are cells that are able to differentiate into other cells and have immunomodulatory properties that are used to treat inflammatory diseases. MSCs have the ability to repair damaged tissue by regenerating damaged tissue. MSCs produce a secretome, where the MSC secretome has various cytokines, chemokines, growth factors, anti-inflammatory factors and proteins that are produced in molecular form. One of the molecules secreted by the secretome is Interleukin-10.IL-10 is an anti-inflammatory cytokine which functions to inhibit the production of several other types of cytokines such as TNF, IL-1, chemokine and IL-12). Apart from that, IL-10 is able to inhibit the function of macrophages in assisting T cell activity. One of the products from Secretome MSC is a cream preparation. To find out whether the MSC cream contains IL-10 protein, Interleukin-10 levels were analyzed in the MSC secretome cream with 3 different MSC cream concentration formulations (2%, 3% and 5%). Analysis of IL-10 levels was carried out using ELISA to detect IL-10 antigen. The results of the examination of 9 samples showed that all samples were positive for IL-10 with a concentration of 2% dilution 1:2 showing the best results with an Optical Density (OD) of 0.069 and followed by a concentration of 5% dilution 1:2 showing an OD value of 0.065.
STRATEGI PEMBELAJARAN IPS MELALUI METODE KOOPERATIF (STUDI KASUS KELAS VII DI SMPN SATAP 8 SOJOL TAHUN PELAJARAN 2023/ 2024) ., Marlina; Kandori, Iwan; Rumbayan, Linda
Literacy: Jurnal Pendidikan Ekonomi Vol. 5 No. 1s (2024): Special Isuee
Publisher : Jurusan Pendidikan Ekonomi Fakultas Ekonomi dan Bisnis UNIMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53682/jpeunima.v5i1s.8674

Abstract

ABSTRAK Penelitian ini bertujuan untuk mengetahui (1) Proses perencanaan penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (2) Pelaksanaan penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (3) Hasil penilaian pembelajaran penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (4) Kendala dalam penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (5) Upaya yang ditempuh untuk mengatasi kendala- kendala dalam menerapkan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol. Adapun metode yang digunakan dalam penelitian ini yaitu penelitian kualitatif. Teknik pengumpualan data yaitu dengan cara observasi, interview/wawancara dan dokumen. Adapun tahapan penelitian ini berupa level yang meliputi perencanaan, pelaksanaan, pengamatan, dan refleksi, dan dilaksanakan tiga level. Hasil penelitian membuktikan bahwa strategi pembelajaran IPS melalui metoda kooperatif multi level dapat meningkatkan prestasi siswa dalam pelajaran IPS kelas VII SMPN Satap 8 sojol. Hasil observasi di lapangan menunjukkan bahwa dari tahap I, tahap II, dan tahap III tampak terjadi perubahan yang signifikan pada proses pembelajaran IPS. Hal ini dapat dibuktikan dengan perubahan nilai atau prestasi yang setiap level makin meningkat, ditambah siswa lebih aktif dan bersemangat dalam proses pembalajaran IPS. Kata Kunci: Model pembelajaran problem based learning, metoda kooperatif, Strategi Pembelajaran SOCIAL STUDIES LEARNING STRATEGY THROUGH COOPERATIVE METHODS (CASE STUDY CLASS VII AT SMPN SATAP 8 SOJOL ACADEMIC YEAR 2023/2024) ABSTRACT This research aims to determine (1) The planning process for implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 Sojol (2) Implementation of implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 sojol (3) Results of learning assessments implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 sojol (4 ) Obstacles in implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 Sojol (5) Efforts taken to overcome obstacles in implementing social studies learning strategies through multi-level cooperative methods in improving the learning achievement of class VII students in social studies subjects at SMPN Satap 8 Sojol. The method used in this research is qualitative research. Data collection techniques are by means of observation, interviews/interviews and documents. The stages of this research are levels which include planning, implementation, observation and reflection, and are carried out at three levels. The research results prove that the social studies learning strategy through multi-level cooperative methods can improve student achievement in class VII social studies at SMPN Satap 8 Sojol. The results of observations in the field show that from stage I, stage II, and stage III there appears to be a significant change in the social studies learning process. This can be proven by changes in grades or achievements which increase at each level, plus students are more active and enthusiastic in the social studies learning process. Keywords: Problem based learning model, cooperative method, learning strategy
STRATEGI PEMBELAJARAN IPS MELALUI METODE KOOPERATIF (STUDI KASUS KELAS VII DI SMPN SATAP 8 SOJOL TAHUN PELAJARAN 2023/ 2024) ., Marlina; Kandori, Iwan; Rumbayan, Linda
Literacy: Jurnal Pendidikan Ekonomi Vol. 5 No. 1s (2024): Special Isuee
Publisher : Jurusan Pendidikan Ekonomi Fakultas Ekonomi dan Bisnis UNIMA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53682/jpeunima.v5i1s.8674

Abstract

ABSTRAK Penelitian ini bertujuan untuk mengetahui (1) Proses perencanaan penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (2) Pelaksanaan penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (3) Hasil penilaian pembelajaran penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (4) Kendala dalam penerapan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol (5) Upaya yang ditempuh untuk mengatasi kendala- kendala dalam menerapkan strategi pembelajaran IPS melalui metoda kooperatif multi level dalam meningkatkan prestasi hasil belajar siswa kelas VII pada mata pelajaran IPS di SMPN Satap 8 sojol. Adapun metode yang digunakan dalam penelitian ini yaitu penelitian kualitatif. Teknik pengumpualan data yaitu dengan cara observasi, interview/wawancara dan dokumen. Adapun tahapan penelitian ini berupa level yang meliputi perencanaan, pelaksanaan, pengamatan, dan refleksi, dan dilaksanakan tiga level. Hasil penelitian membuktikan bahwa strategi pembelajaran IPS melalui metoda kooperatif multi level dapat meningkatkan prestasi siswa dalam pelajaran IPS kelas VII SMPN Satap 8 sojol. Hasil observasi di lapangan menunjukkan bahwa dari tahap I, tahap II, dan tahap III tampak terjadi perubahan yang signifikan pada proses pembelajaran IPS. Hal ini dapat dibuktikan dengan perubahan nilai atau prestasi yang setiap level makin meningkat, ditambah siswa lebih aktif dan bersemangat dalam proses pembalajaran IPS. Kata Kunci: Model pembelajaran problem based learning, metoda kooperatif, Strategi Pembelajaran SOCIAL STUDIES LEARNING STRATEGY THROUGH COOPERATIVE METHODS (CASE STUDY CLASS VII AT SMPN SATAP 8 SOJOL ACADEMIC YEAR 2023/2024) ABSTRACT This research aims to determine (1) The planning process for implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 Sojol (2) Implementation of implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 sojol (3) Results of learning assessments implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 sojol (4 ) Obstacles in implementing social studies learning strategies through multi-level cooperative methods in improving the learning outcomes of class VII students in social studies subjects at SMPN Satap 8 Sojol (5) Efforts taken to overcome obstacles in implementing social studies learning strategies through multi-level cooperative methods in improving the learning achievement of class VII students in social studies subjects at SMPN Satap 8 Sojol. The method used in this research is qualitative research. Data collection techniques are by means of observation, interviews/interviews and documents. The stages of this research are levels which include planning, implementation, observation and reflection, and are carried out at three levels. The research results prove that the social studies learning strategy through multi-level cooperative methods can improve student achievement in class VII social studies at SMPN Satap 8 Sojol. The results of observations in the field show that from stage I, stage II, and stage III there appears to be a significant change in the social studies learning process. This can be proven by changes in grades or achievements which increase at each level, plus students are more active and enthusiastic in the social studies learning process. Keywords: Problem based learning model, cooperative method, learning strategy
Ukhuwah Islamiyah Dalam Kehidupan Bermasyarakat ., Nurawalia; ., Marlina; Amin, M.
Jurnal Kajian Islam dan Sosial Keagamaan Vol. 3 No. 3 (2026): Januari - Maret
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This article discusses the concept of Islamic brotherhood (ukhuwah Islamiyah) as a fundamental principle in building unity and harmony among Muslims. The purpose of this study is to explain the meaning, essence, and foundations of ukhuwah Islamiyah, identify factors that hinder its realization, and propose efforts to strengthen Islamic brotherhood in social life. This study employs a qualitative descriptive approach through literature review by analyzing relevant references such as the Qur’an, Hadith, and scholarly works related to ukhuwah Islamiyah. The results show that ukhuwah Islamiyah is a spiritual and social bond based on faith and piety, which plays a crucial role in maintaining unity, tolerance, and cooperation among Muslims. Factors hindering ukhuwah include arrogance, negative prejudice, unmanaged differences of opinion, and lack of awareness of the importance of brotherhood
Door-to-Needle Time Sebagai Indikator Mutu Pelayanan pada Trombolisis Intravena Stroke Iskemik Akut: Serial Kasus ., Marlina; Heri, Raissa Alfaathir
Jurnal Sains Farmasi Dan Kesehatan Vol. 3 No. 3 (2026): Januari - April
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v3i3.4379

Abstract

Acute ischemic stroke is a neurological emergency requiring prompt reperfusion therapy to prevent irreversible brain injury. Intravenous thrombolysis with alteplase has been shown to improve functional outcomes when administered within ≤4.5 hours of symptom onset. Door-to-Needle Time (DNT) is a key quality indicator directly associated with clinical prognosis. We report three cases of acute ischemic stroke (aged 57–66 years; two females and one male) who received intravenous thrombolysis at a tertiary care hospital. The respective DNTs were 43 minutes, 48 minutes, and 53 minutes. All patients presented with mild-to-moderate focal neurological deficits (hemiparesis, dysarthria/aphasia) within 4.5 hours of symptom onset. Two patients demonstrated clinical improvement without hemorrhagic complications. One patient developed mild mucosal bleeding without symptomatic intracranial hemorrhage, leading to early discontinuation of the infusion. Achievement of DNT ≤60 minutes in all three cases reflects effective multidisciplinary coordination through an established code stroke system. Clinical challenges, such as hypertensive emergencies, can be managed without prolonging DNT when standardized protocols are optimally implemented.
Co-Authors ., Nurawalia A. Tubagus Surur Adek Zamrud Adnan Aditya Willy Putra Agus Wartiningsih Akmal Djamaan AM. M. Hafidz MS Andani Eka Putra Arfiandi Arfiandi Armenia, Armenia Asrori . Densi Selpia Sopianti Densi Selpia Sopianti Desti Wulandari Endang Purwati Fitri Amalinda Hajidin . Hanna Sari Widya Kusuma Harfia Mudahar Hari, Dewi Gulyla Heri, Raissa Alfaathir Ika Adhani Sholihah Ikhwan Resmala Sudji Irene Puspa Dewi Iwan Kandori M Ikhsan M. Amin Martono . Mitsuaki Nishibuchi Muhammad Taher Nella Novita P Pachaly Rahmi Novita Regina Handayani Handayani, Regina Handayani Rizal Rizal Rizki Rahmadian Rumbayan, Linda Rustini Rustini Satrio Haryo Benowo Wibowo Sesilia Seli Son Radu Suci Rahmawati Surya Dharma Vika Amelia Wahyu Setia Widodo Wahyu Widowati Yufri Aldi Yusrizal .