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All Journal Jurnal Media Gizi Indonesia (MGI) Amerta Nutrition Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal ARTERI : Jurnal Ilmu Kesehatan Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Layanan Masyarakat (Journal of Public Service) Epidemiology and Society Health Review (ESHR) Medika Respati : Jurnal Ilmiah Kesehatan Nutriture Journal
Rooiqoh, Qothrunnadaa Fajr
Department Of Postgraduate Nutrition Science, Sebelas Maret University, Surakarta
Humanities Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Pengaruh Hipolipidemia Formulasi Tepung Umbi Suweg (Amorphophallus paeoniifolius) dan Tepung Kacang Bogor (Vigna subterranea) terhadap Kadar HDL dan LDL: Hypolipidemic Effect of Suweg Tuber Flour (Amorphophallus paeoniifolius) and Bogor Bean Flour (Vigna subterranea) Formulation on HDL and LDL Levels Rahmania, Rizka Azkia; Rooiqoh, Qothrunnadaa Fajr; Pinasti, Ladyamayu; Luthfiya, Lulu’
Amerta Nutrition Vol. 9 No. 1SP (2025): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 5th Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i1SP.2025.271-280

Abstract

Background: Data from the 2023 Indonesian Health Survey indicate that diabetes mellitus (DM) affects a substantial proportion of the Indonesian among populations aged ≥15 years (11.7%). Among individuals with type 2 diabetes mellitus (T2DM), diabetic dyslipidemia is a prevalent metabolic disorder, particularly characterized by reduced high-density lipoprotein (HDL) levels accompanied by elevated low-density lipoprotein (LDL) levels. Improvement in blood lipid profiles may be supported by the consumption of suweg tubers and Bambara groundnuts as local food sources with high dietary fiber content. Objectives: The present study evaluated the effectiveness of combined suweg tuber and Bambara groundnut flour formulation as dietary interventions to modulate lipid metabolism, specifically focusing on HDL and LDL levels, in rats with diabetes-inducted dyslipidemia. Methods: An experimental approach was conducted using a randomized control group with pre- and post-intervention measurements. Thirty male Sprague-Dawley rats were assigned into five groups: a negative control group (K-), a positive control group (K+), and three treatment groups (F1, F2, and F3) which received formulations at doses of 0.37 g, 0.39 g, and 0.42 g per 200 g BW, respectively. Fasting blood glucose (FBG), HDL, and LDL concentrations were assessed before and after the intervention. Statistical analyses included the Shapiro-Wilk normality test, paired t-test, homogeneity test, and one-way ANOVA, and Tukey Post Hoc analysis. Results: The F1 group had the highest HDL (77.2 ± 2.0 mg/dL) and lowest LDL (27.0 ± 1.5 mg/dL). These differences were statistically significant across groups (p-value < 0.001). Conclusions: The F1 formulation was effective in increasing HDL levels while reducing LDL levels, indicating the potential of suweg tuber and Bambara groundnut flours as functional dietary interventions for diabetic dyslipidemia.
Co-Authors Almira Sitasari Amala, Nur Amara, Qudwatun Niswah Amilia Yuni Damayanti Claresta, Ivena Dewi, Sundari Fortuna Didik Gunawan Tamtomo Didik Gunawan Tamtomo Fadholah, Amal Fathimah Fathimah, Fathimah Hafidhotun Nabawiyah, Hafidhotun Hilaliah, Dini Dzulfa Indahtul Mufidah Islami, Merdina Jannah, Hani’atu Anharil Kholid Karomi Luthfiya, Lulu' Luthfiya, Lulu’ Matdoan, Maulidia Mahmudah Nabilah, Yumna Amirotin Najiebah, Arwa Pibriyanti, Kartika Pinasti, Ladyamayu Pribriyanti, Kartika Putri, Ashifa Purnama Qurroti, A’yun Rahayu, Try Rahmania, Rizka Azkia Rana, Annisa Rini Wuri Astuti, Rini Wuri Risya Cilmiaty Risya Cilmiaty Rizky, Aulivia Ahma Salbila, Ahda Sukowati, Dewi Susi Nurohmi Widyawati, Herni Endah Woro, Upik