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Stabilitas Asiatikosida dalam Proses Pembuatan Film Penutup Luka Kitosan yang Mengandung Asiatikosida Yuni Anggraeni
Jurnal Kimia Valensi Jurnal VALENSI Volume 4, No. 2, November 2014
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3801.517 KB) | DOI: 10.15408/jkv.v0i0.3613

Abstract

Solubility Enhancement of Ethyl AcetateFraction of The Artocarpus altilis (Parkinson) Fosberg Leaves with Addition of β-Cyclodextrin-HPMC by Using Kneading Method Sabrina Sabrina; Yuni Anggraeni; Berti Puspitasaril; LBS Kardono
Jurnal Kimia Valensi Jurnal Valensi Volume 4, No.1, Mei 2014
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.533 KB) | DOI: 10.15408/jkv.v4i1.1077

Abstract

Abstract Ethyl acetate fraction of the Artocarpus altilis (Parkinson) Fosberg extract have a potency to treat the cardiovascular diseases have poorly solubility in water. The purpose of this study was to improve the solubility of the extract. One of method to improve the solubility of the extract by mixing with cyclodextrin polymers and their derivatives. Hydroxyl propyl methylcellulose (HPMC) as a water-soluble polymer can enhance the β-cyclodextrin (β-CD) activity. Three comparisons extract and ß-cyclodextrin were: 1:2, 1:4, and 1:6 by mixing with the addition hydroxyl propyl methylcellulose 0.12%of the total weight of extract and β-CD for each formula. The sample was prepared by kneading method. The sample characterization was used Karl Fischer titration, Scanning Electron Microscopy and solubility study.Content of total flavonoid from the extract was 32.7%. The Result showed that the addition polymer combination of β-CD + HPMC caused increasing the solubility of extract in water7.04% (F1), 19.47% (F2) and 59.92% (F3) compared to extract control with significant differences at level of confidence 95% (p ≤ 0.05). Keywords : ethyl acetate fraction of breadfruit, kneading method, β-cyclodextryn, hydroxy propyl methylcellulose, total flavonoid
Kajian Mutu Produk Tablet Metformin Hidroklorida Extended-Release yang Dipasarkan di Indonesia Yuni Anggraeni; Umniyaty Mufidah; Umar Mansur
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 3, No 2 (2021)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v3i2.24755

Abstract

Some metformin hydrochloride extended-release (MetHCl-XR) tablet products have been marketed in Indonesia with varying prices. In general, price is considered to indicates the quality of a product. This research was conducted to review the products quality, especially the dissolution rate of the products, and to find out if the price is an indicator of the product quality. Three brands of MetHCl 500 mg XR tablets were randomly selected, namely Tablet A, B, and C which the price of Tablet B > A > C, then the Tablets were characterized. The results showed that Tablet A, B, and C contain MetHCl with an average of 100.61%, 98.72%, and 101.15% respectively, and met the uniformity of dosage unit requirement. Tablet A met the requirements of dissolution tests 1, 2, 3, and 4, while Tablet B and C met the requirements of dissolution tests 1 and 3. The cumulative percentage of MetHCl release at the 10th hour of Tablet A, B, and C were 94.18%, 97.24%, and 94.59% respectively with the release kinetics of Tablet A and B following Higuchi model, whereas Tablet C following a first-order. Drug release of all tablets occurred in non-Fick diffusion. In conclusion, the three tablets met the standards required by USP 43 and the price is not an indicator of MetHCl-XR tablet products quality.
Formulasi Emulgel Gamma Oryzanol dengan Menggunakan Carbopol sebagai Gelling Agent Sabrina Dahlizar; Nurkhasanah Nurkhasanah; Ofa Suzanti Betha; Yuni Anggraeni
Jurnal Sains Farmasi & Klinis Vol 9, No 2 (2022): J Sains Farm Klin 9(2), Agustus 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (798.046 KB) | DOI: 10.25077/jsfk.9.2.129-137.2022

Abstract

Gamma-oryzanol merupakan senyawa antioksidan alami yang diperoleh dari minyak dedak padi atau yang lebih dikenal dengan rice bran oil (RBO). Gamma-oryzanol diketahui dapat melindungi kulit dari radiasi ultraviolet dan meningkatkan kelembaban kulit, sehingga dapat dimanfaatkan sebagai antikerut dan pelembab kulit di bidang kosmetik. Terdapat dua komponen penting yang menentukan sifat fisik emulgel, yaitu emulgator dan gelling agent. Penelitian ini bertujuan untuk membandingkan pengaruh variasi konsentrasi polimer karbopol 940 sebagai gelling agent terhadap sifat fisik emulgel gamma-oryzanol. Konsentrasi karbopol 940 yang digunakan dalam formulasi adalah 0,5% (pada F1), 0,75% (pada F2) dan 1 % (pada F3). Evaluasi sifat dan stabilitas fisik sediaan emulgel dilakukan terhadap beberapa parameter uji, yaitu pengamatan organoleptis, pengukuran diameter globul rata-rata, penentuan pH, penentuan sifat alir dan kekentalan, uji daya sebar dan uji sentrifugasi. Evaluasi stabilitas fisik sediaan emulgel dilakukan dengan menggunakan metode penyimpanan pada suhu 4oC, 26±2oC dan 40oC, uji cycling test dan uji sentrifugasi. Hasil penelitian menunjukkan bahwa variasi konsentrasi karbopol 940 berpengaruh terhadap sifat dan stabilitas fisik sediaan. Peningkatan konsentrasi karbopol 940 menyebabkan terjadinya peningkatan viskositas emulgel dan ukuran diameter globul rata-rata, serta  penurunan daya sebar. Uji stabilitas fisik menunjukkan ketiga formula sediaan emulgel gamma-oryzanol mengalami perubahan nilai parameter uji yang tidak bermakna pada sifat organoleptis. Berdasarkan hasil uji sentrifugasi, emulgel yang mengandung Carbopol 0,75% (F2) memiliki stabilitas fisik terbaik. 
The Effect of Health Education Video Based on Islamic Purification Jurisprudence on Handwashing Intention Nurmeilis; Nurrika, Dieta; Anggraeni, Yuni; Alkaff, Raihana Nadra; Sukmayanti, Zanastia
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 7 No 2 (2023): Medical Technology and Public Health Journal September 2023
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v7i2.4939

Abstract

This study aimed to determine the effectiveness of health education videos based on Islamic purification fiqh on students’ intention to wash their hands using and buying clay soap by applying the theory of planned behavior. A two-armed pre-post intervention was conducted in Banten from February to August 2022. Participants were randomly assigned to an intervention or a control group. The total sample of this research is 187 respondents. This study found that the intention to wash hands using clay soap before and after the short video educational media intervention increased by 4.3%, and the intention to buy it increased by 4.8%. In the three variables that construct the intention to wash hands using clay soap, only the subjective norm variable is related to the behavioural intention to use clay soap. Religious reasons have the potential to increase handwashing behaviour using clay soap. Short video educational media interventions targeting Generation Z can be carried out to increase the intention to practice handwashing.
ANALYSIS OF TOURIST PERCEPTIONS IN SITU BAGENDIT BASED ON THE 6A TOURISM COMPONENTS Anggraeni, Yuni
SABA: Journal of Tourism Research Vol 2, No 1 (2024): Saba : Journal of Tourism Research
Publisher : Universitas Pendidikan Indonesia (UPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Situ Bagendit it is one of tourist attraction often visited by tourist. Situ Bagendit increased in the of number visits after there is new renovation compared to before. However, in its development by the Tourism and Culture Office of Garut Regency Government., Situ Bagendit there are still shortcomings such as petrol station, parking place, and toilet. With these problem then it is necessary to conduct research on tourist perception based on tourism component 6A (Attraction, Accessibility, Amenities, Ancillary Service, Accommodation and Activity). Besides that, benefit from conduct research for The Tourism and Culture Office of Garut Regency Government. to pay more attention facilities and improved quality Situ Bagendit in the future. The methode used in this study that is quantitative methodes with purpose sampling. This is research distributing questionnaire with the sample 100 respondents. The results of this analysis obtained form the results minimum, maximum, mean and respondent achievement level. The result obtained by the authors indicate that tourist perception of attraction, accessibility, and amenities are in the quite good. Tourist perception of ancillary service are in the poor category. Finally tourist perception of accommodation and activity are in the quite good.
Implementing Discipline for Early Childhood: Strategies and Teacher Roles Destiana, Evie; Anggraeni, Yuni; Fatmala, Endang; Wulandari, Andini
Procedia of Social Sciences and Humanities Vol. 6 (2024): International Conference Psychology and Education Transformation For Bright Future
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/pssh.v6i.537

Abstract

Discipline is one of the characters that needs to be applied from an early age, especially by parents. The fact is that there are still many parents who do not understand and are moved to apply disciplinary behavior to their children. The purpose of this study is to analyze the role of teachers in optimizing the development of discipline application from early childhood. This research uses a qualitative approach with the type of research used, namely descriptive qualitative research. Data collection was carried out using interview, observation and documentation methods. Sources of research data are the principal, 1 assistant teacher or companion teacher 2 and 68 students. The researcher is the core instrument in the research and uses supporting instruments in the form of interview guidelines, observation guidelines. The analysis technique used is descriptive analysis from Miles & Huberman using an interactive model. The results showed that the teacher's role in children's discipline is as a good role model for children, teachers as educators and mentors by introducing and familiarizing children with discipline in everyday life, and teachers as evaluators. The teacher's efforts in implementing discipline are exemplary, habituation, and using reward and punishment methods. Factors that hinder teachers in implementing children's disciplinary attitudes are external factors, namely family, community environment, internal factors of hyperactive or tantrum children's attitudes. The supporting factor is the role of parents who are willing to cooperate well in developing their children's disciplinary attitudes. It can be concluded that teachers have an important role in shaping student discipline at school.
Karakteristik Fisik dan Aktivitas Antibakteri Sabun Cair Minyak Nilam (Pogostemon cablin Benth.) yang Berbasis Surfaktan Sodium Lauril Eter Sulfat Anggraeni, Yuni; Nisa', Fakhrun; Betha, Ofa Suzanti
Jurnal Kefarmasian Indonesia VOLUME 10, NOMOR 1, FEBRUARI 2020
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v10i1.499

Abstract

Patchouli oil obtained from patchouli plants (Pogostemon cablin Benth.) has been widely used as an antibacterial agent in liquid and solid soap preparation. In this research, patchouli oil was added to liquid soap formula which use sodium lauryl ether sulphate (SLES) surfactant. The purpose of this study was to determine the physical characteristics and antibacterial activity of patchouli oil liquid soaps based on SLES surfactant. The Liquid soaps were prepared into four formulas with variation of patchouli oil concentration that were F0 (0.00% w/w), F1 (0.05% w/w), F2 (0.50% w/w), and F3 (1.00% w/w). The liquid soaps were evaluated including organoleptic, microscopic property, physical stability by using centrifuge test, pH, foam height and stability, viscosity and rheology, and antibacterial activity against Staphylococcus aureus ATCC 25923 by using disc diffusion method and chloramphenicol as a positive control. The results showed that all liquid soap formulas had following characteristics: translucent except F3 slightly murky, homogen, stable after centrifuge test, pH between 6.55 – 6.66 that were no significantly different and met SNI standards of liquid soap, foam height between 2.67 – 3.23 cm that were no significantly different and stable after 5 minutes of testing, viscosity between 2237 – 2397 cPs relatively equal in all formulas with pseudoplastic rheological properties. The patchouli oil liquid soaps had antibacterial activity against Staphylococcus aureus ATCC 25923, where F0, F1, F2, F3 and positive control result in inhibition zone diameter of 11.26±2.60 mm, 14.60 ± 2.45mm, 15.51 ± 0.44 mm, 17.97 ± 0.71 mm and 19.00 ± 3.92 mm respectively. Based on the ANOVA one way test, the addition of 1% patchouli oil gave a significant effect on the inhibition zone diameter compared to F0 (without patchouli oil)
Formulasi Emulgel Gamma Oryzanol dengan Menggunakan Carbopol sebagai Gelling Agent Dahlizar, Sabrina; Nurkhasanah, Nurkhasanah; Betha, Ofa Suzanti; Anggraeni, Yuni
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 No 2 (2022): J Sains Farm Klin 9(2), Agustus 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.2.129-137.2022

Abstract

Gamma-oryzanol merupakan senyawa antioksidan alami yang diperoleh dari minyak dedak padi atau yang lebih dikenal dengan rice bran oil (RBO). Gamma-oryzanol diketahui dapat melindungi kulit dari radiasi ultraviolet dan meningkatkan kelembaban kulit, sehingga dapat dimanfaatkan sebagai antikerut dan pelembab kulit di bidang kosmetik. Terdapat dua komponen penting yang menentukan sifat fisik emulgel, yaitu emulgator dan gelling agent. Penelitian ini bertujuan untuk membandingkan pengaruh variasi konsentrasi polimer karbopol 940 sebagai gelling agent terhadap sifat fisik emulgel gamma-oryzanol. Konsentrasi karbopol 940 yang digunakan dalam formulasi adalah 0,5% (pada F1), 0,75% (pada F2) dan 1 % (pada F3). Evaluasi sifat dan stabilitas fisik sediaan emulgel dilakukan terhadap beberapa parameter uji, yaitu pengamatan organoleptis, pengukuran diameter globul rata-rata, penentuan pH, penentuan sifat alir dan kekentalan, uji daya sebar dan uji sentrifugasi. Evaluasi stabilitas fisik sediaan emulgel dilakukan dengan menggunakan metode penyimpanan pada suhu 4oC, 26±2oC dan 40oC, uji cycling test dan uji sentrifugasi. Hasil penelitian menunjukkan bahwa variasi konsentrasi karbopol 940 berpengaruh terhadap sifat dan stabilitas fisik sediaan. Peningkatan konsentrasi karbopol 940 menyebabkan terjadinya peningkatan viskositas emulgel dan ukuran diameter globul rata-rata, serta  penurunan daya sebar. Uji stabilitas fisik menunjukkan ketiga formula sediaan emulgel gamma-oryzanol mengalami perubahan nilai parameter uji yang tidak bermakna pada sifat organoleptis. Berdasarkan hasil uji sentrifugasi, emulgel yang mengandung Carbopol 0,75% (F2) memiliki stabilitas fisik terbaik. 
WOMEN’S LANGUAGE IN JENNY HAN’S SERIES “THE SUMMER I TURNED PRETTY” Anggraeni, Yuni; Iskandar, Iskandar; Bakri, Fitriyani
Journal of English Literature and Linguistic Studies Vol 3, No 1 (2024): Journal of English Literature and Linguistic Studies (JELLS) - Nov 2024
Publisher : Faculty of Languages and Literature, Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/jells.v3i1.67632

Abstract

This research discusses the language of women contained in the series 'The Summer I Turned Pretty'. This research aims to analyze the female language contained in the series 'The Summer I Turned Pretty' by using Lakoff's theory (1973 & 1975) to analyze ten features of women’s language. The research method used in this study is descriptive qualitative method. The researcher analyzed the women’s language in the series 'The Summer I Turned Pretty' which amounted to 7 episodes and lasted about 45 minutes each. The result of this study shows that 10 features of female language were found in the series. The features of women’s language including lexical hedges or fillers, tag questions, rising intonation on declaratives, empty adjectives, precise color terms, intensifiers, hypercorrect grammar, ‘superpolite’ forms, avoidance of strong swear words, and emphatic stress. The reason women use the features of the female language is because to cover themselves from self-confidence or make them feel confident when using these features. From the 10 data observed, the researcher concludes that some features have similar purposes but different uses.