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All Journal Jurnal Sosialisasi: Jurnal Hasil Pemikiran, Penelitian dan Pengembangan Keilmuan Sosiologi Pendidikan Indonesian Journal of Cancer Chemoprevention Indonesian Journal of Pharmaceutical Science and Technology Equilibrium: Jurnal Pendidikan Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Ilmiah Cendekia Eksakta Pinisi Business Administration Review Daengku: Journal of Humanities and Social Sciences Innovation Jurnal Ilmiah Bakti Farmasi Social Landscape Journal Media Farmasi Indonesia Pinisi Journal of Sociology Education Review The Journal of Anti Money Laundering and Countering The Financing of Terrorism (AML/CFT Journal) Jurnal Pengabdian Masyarakat Ininnawa: Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Paramacitra : Jurnal Pengabdian Masyarakat DISCOURSE : Indonesian Journal of Social Studies and Education EDUSOS: Jurnal Edukasi dan Ilmu Sosial Journal of Pharmascience
Ibrahim Arifin
Fakultas Farmasi, Universitas Wahid Hasyim
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Other

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The Paradox of Coastal Modernization: Urban Transformation in Makassar’s Centre Point of Indonesia Arifin, Ibrahim; Nur, Muhammad; Musdalifah, Musdalifah; Diki, Hendrawan; Mutmainnah M., Ulfah
DISCOURSE: Indonesian Journal of Social Studies and Education Vol. 3 No. 1 (2025): November
Publisher : Citra Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69875/djosse.v3i1.222

Abstract

Coastal development has become a crucial discourse in studies of development and urbanization, revealing the tension between economic growth and social inequality. Many coastal cities in Southeast Asia, including Indonesia, have adopted land reclamation projects as strategies to strengthen their modern image and economic competitiveness. However, these projects often generate social displacement, ecological degradation, and the marginalization of local communities. This study aims to understand how coastal residents and visitors interpret spatial transformation, adapt to socio-economic changes, and negotiate their positions within the Centre Point of Indonesia (CPI) development project in Makassar. Employing a critical ethnographic approach, data were collected through field observations, in-depth interviews with residents and visitors, and analysis of online media reports. The findings reveal three major dynamics: the transformation of urban infrastructure and accessibility, the emergence of new, exclusive economies, and local communities’ social adaptation strategies to modernization. This study concludes that the CPI project embodies the paradox of coastal modernization, economic growth accompanied by the reproduction of spatial inequality, while contributing to theoretical debates in development sociology concerning spatial justice and local community participation in urban development practices in Indonesia.
Kesenjangan Infrastruktur Dasar dan Dampaknya Pada Kualitas Hidup di Kampung Pemulung Savana Kota Makassar Arifin, Ibrahim; Ahmad, M.Ridwan Said; Arifin, Zulkifli; Arifin, Ibrahim Ibrahim
Equilibrium: Jurnal Pendidikan Vol. 14 No. 1 (2026): EQUILIBRIUM : JURNAL PENDIDIKAN
Publisher : Universitas Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/14052970

Abstract

This study analyzes the gap in basic infrastructure in the Pemulung Savana Settlement, Makassar City, and its impact on the quality of life of the community. This research employs a descriptive qualitative method, with data collection techniques including observation, in-depth interviews, and documentation. Data analysis is conducted using a thematic method to identify key problem patterns. The findings reveal that limitations in basic infrastructure such as restricted access to clean water, poor sanitation systems, unstable electricity, and inadequate roads and transportation negatively affect the well-being of the community. The lack of educational and healthcare facilities worsens socio-economic conditions, leading to low health levels and limited educational opportunities for children. The absence of essential services also increases the risk of disease and exacerbates poverty. Furthermore, the unclear land ownership status hinders infrastructure improvement efforts. These findings highlight that infrastructure disparities in marginal areas require serious attention from various stakeholders to develop inclusive and sustainable solutions. Improving access to basic services and implementing more equitable development policies are essential to enhancing the quality of life in the area.
Formulation and Anti-Hypertensive Activity of Ambon Banana Peel Foam Mat Drying Granules as a Nutraceutical Arifin, Ibrahim; Anwar, Khoirul; Shabrina, Ayu; Wibowo, Danang Novianto; Amirudin, Muhammad Subhan; Kumalasari, Wahyu; Angelita, Anastasya; Mastuti, Sri; Inayati, Dian
Indonesian Journal of Pharmaceutical Science and Technology Vol 13, No 1 (2026)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v13i1.63013

Abstract

Ambon banana peel (ABP) is rich in phenolic compounds yet unstable to light and heat. Foam-mat drying (FMD) protects bioactive components and facilitates the development of nutraceutical products. This study aimed to formulate and evaluate FMD granules containing ABP for their antioxidant and antihypertensive activities. Granules were prepared with ABP at 1% (F1), 2.5% (F2), and 5% (F3) w/w, combined with 6% Tween-80 and 15% maltodextrin, dried at 40 °C for 60 min, and blended with excipients. Physical characteristics, pH, flowability, and antioxidant activity (ABTS assay) were assessed. Antihypertensive effects were tested in Wistar rats induced with 2% NaCl and treated orally for 14 days; captopril (5 mg/kg BW) served as a positive control. Data were analyzed by one-way ANOVA. All formulations produced free-flowing granules with a moisture content <2% and a dissolution time <5 min. Antioxidant inhibition increased with ABP content, with F3 showing the highest activity (71.3 ± 1.4%). F3 also achieved the greatest reductions in systolic (≈31%) and diastolic (≈39%) blood pressure, approaching the effect of captopril. Moreover, F3 exhibits strong antioxidant activity and significant antihypertensive effects, indicating potential as a sustainable nutraceutical for the management of hypertension. Further studies on product stability and clinical efficacy are warranted.
Efek Hepatoprotektor Ekstrak Etanol Daun Kenikir (Cosmos caudatus Kunth.) Pada Tikus Yang Diinduksi Doksorubisin Junvidya Heroweti; Ibrahim Arifin; Nurul Arlin Hidayati; Rizki Suciantika
Journal of Pharmascience Vol. 6 No. 2 (2019): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7348

Abstract

ABSTRAK Doksorubisin adalah agen kemoterapi yang mempunyai efek samping hepatotoksik dengan cara pembentukan radikal bebas. Daun kenikir (Cosmos caudatus Kunth.) memiliki potensi untuk mencegah efek hepatotoksik akibat penggunaan doksorubisin. Penelitian bertujian untuk membuktikan potensi Ekstrak Etanol Daun Kenikir (EEDK) sebagai hepatoprotektor pada tikus yang diinduksi doksorubisin. Penelitian ini merupakan penelitian eksperimental menggunakan randomized matched post only control group design. Sebanyak 25 ekor tikus galur wistar dibagi menjadi 5 kelompok secara acak. Kelompok I, control normal diberi asupan aquadest, kelompok II kontrol hepatotoksik diberikan doksorubisin dosis 5 mg/KgBB. Kelompok III, IV dan V merupakan kelompok perlakuan EEDK dengan dosis berturut-turut 250,500, dan 1000 mg/kgBB dengan doksorubisin dosis 5 mg/kgBB. Pemberian doksorubisin dilakukan pada hari ke-1, ke-5,ke-9 dan hari ke-13 secara intraperitonial (ip) dan pemberian EEDK dilakukan 1 kali sehari selama 14 hari secara peroral (po). SEluruh hewan uji diambil darahnya pada hari ke-15. Kadar SGOT dan SGPT dievaluasi untuk melihat adanya kerusakan hati. Data kadar SGOT dianalisis dengan one way anova, sedangkan data kadar SGPT dianalisis menggunakan Kruskall-wallis. Hasil penelitian menunjukkan bahwa doksorubisin dapat menyebabkan hepatotoksik ditandai dengan peningkatan kadar SGOT dan SGPT. Ekstrak etanol daun kenikir mampu memberikan efek hepatoprotektor yang signifikan (p≤0,05) pada tikus yang diinduksi doksorubisin ditunjukkan dengan penurunan kadar SGOT dan SGPT. Kata Kunci: doksorubisin, daun kenikir, hepatoprotektor, SGOT, SGPT  ABSTRACT Doxorubicin is a chemotherapeutic agent has hepatotoxic side effects through the formation of free radicals. Marigold leaves (Cosmos caudatus Kunth.) has the potential to prevent hepatotoxic effects caused by the use of doxorubicin. This study aims to prove the potential of Ethanol Extract of Marigold Leaves (EEDK) as a hepatoprotector in doxorubicin-induced rats. This study was an experimental study with a randomized matched post test only control group design. 25 wistar male rats were divided into 5 groups randomly. Group I as normal control was given aquadest intake, group II as hepatotoxic control was given doxorubicin dose 5 mg/Kg BW, group III, IV and V was EEDK treatment group dose 250, 500 and 1000 mg/Kg BW and doxorubicin dose 5 mg/Kg BW. Doxorubicin was given on day 1, 5, 9 and 13intraperitoneal (i.p) and EEDK was given once a day for 14 days orally (p.o). All blood samples were taken on the 15th day. SGOT and SGPT levels were evaluated to see liver damage. SGOT level data were analyzed statistically by One Way Anova, while SGPT level data were analyzed using Kruskall-Wallis. The results showed that doxorubicin-induced hepatotoxity characterized by increased SGOT and SGPT levels. Ethanol extract of marigold leaves can provide hepatoprotector effect significantly (p≤0.05) in doxorubicin-induced rats indicate by decreased SGOT and SGPT levels. Keywords: doxorubicin, marigold leaves, hepatoprotector, SGOT, SGPT
Efek Sitotoksik Ekstrak Etanolik Ocimum basilicum, L. Pada Sel Kanker Payudara Devi Nisa Hidayati; Ibrahim Arifin; Fatimatuz Zahroh; Lina Wahyuni
Journal of Pharmascience Vol. 6 No. 2 (2019): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7353

Abstract

ABSTRAK Pengobatan kanker menggunakan bahan alam terus dikembangkan. Salah satu tanaman yang memiliki efek sitotoksik Ocimum basilicum, L. tujuan penelitian ini adalah mengetahui aktivitas sitotoksik dari ekstrak etanol Ocimum basilicum (EEOB) terhadap sel kanker payudara T47D dan MCF7. Ocimum basilicum diekstraksi menggunakan metode maserasi dengan pelarut etanol 70%. Pengujian aktivitas sitotoksik menggunakan metode MTT assay dengan  seri konsentrasi EEOB 1000; 500; 250; 125; 62.5; 31,25 µg/mL. Hasil uji aktivitas sitotoksik EEOB memperlihatkan nilai IC50 pada sel T47D dan MCF-7 sebesar 399.86 µg/ml dan 387.76 µg/ml. Kata Kunci—Sitotoksik, Ocinum basilicum L., T47D, MCF-7  ABSTRACT             Cancer treatment using natural ingredients continues to be developed. One of the plants that is proven to have cytotoxic activity is basil leaves (Ocimum basilicum, L.). This study aims to determine the cytotoxic activity of ethanol extract of basil leaves (EEBL) on T47D and MCF-7 breast cancer cells. Basil leaves were extracted using maceration  with ethanol 70%. The cytotoxic test was perfomed using MTT assay with various EEBL concentrations: 1000; 500; 250; 125; 62.5; 31,25 µg/mL. The results showed that IC50 of cytotoxic activity in T47D and MCF-7 was 399.86 µg/ml and 387.76 µg/ml respectively. Keywords—Cytotoxic, Ocinum basilicum L., T47D, MCF-7
Co-Authors . Anindyajati ., Muhammad Syukur A. Octamaya Tenri Awaru Abdul Rahman Adam Hermawan Agustang, Andi Dodi May Putra Ahmad Fudhail  Majid Ahmad, M Ridwan Said Ahmad, M. Ridwan Said Akbar, Muh. Aksayanti Al Faris, Risman Alimuddin, Ardawati Amirudin, Muhammad Subhan Andi Ima Kesuma Angelita, Anastasya Anis Fauzia Arifin, Ibrahim Ibrahim Arifin, Jamaluddin Arsyada, Muhammad Farih Awaru, Andi Octamaya Tenri Ayu Shabrina Bahri bahri Cahyaning Gita Rizkita Devi Nisa Hidayati Dewi Hastuti Diki, Hendrawan Edy Meiyanto Edy Meiyanto Eka Wahyuni Nurul Qori&#039;ah Endah Subekti Ernawati Syahruddin Kaseng Fachrian, Ahmad Maulana Farikha Maharani Fatimatuz Zahroh Fatimatuz Zahroh Firdaus W Suhaeb Hasni Hasni Heroweti, Junvidya Hidayati, Nurul Arlin HUSNA, ASMA'UL Ilham Saputra Inayati, Dian Jayadi, Abd Asathin Bardan Jumadi Jumadi Kabur, Savio Ricardus Khibran, Muh Fauzan Khoirul Anwar Lina Wahyuni Lina Wahyuni Mubarak, M. Alwi Muddiin, Muhammad Imaa Muhammad Nur Muhammad Syukur Musdalifah Musdalifah Muthi Ikawati Mutiani Mutiani Mutmainnah M., Ulfah N, Muh Ilham Nirwana NUR FADILAH Nur Hidayah Nurfadilla, Rizki Nurmagfira Nurul Arlin Hidayati Pratama, S.Si., M.Si., Mario Pratiwi, Nevy Ramadhan S, Muhammad Syahrul Rijal, Muh. Rizaldi Syam , Muh Rizki Suciantika Sadriani, Andi Safitri, Nurafia Sari Haryanti Sari Haryanti Seppa, Yusi Irensi Sri Mastuti Sri Wahyuni Taufik, Parham Tiara Nur’aini Umi Any Tiyas Wati Wahyu Kumala Sari Wibowo, Danang Novianto Zainal Arifin Zulfafasya, Nisrina Zulkifli Arifin