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All Journal Jurnal Psikologi Perseptual Adi Widya : Jurnal Pengabdian Masyarakat Media Ilmu Kesehatan Jurnal Kesehatan Prima Klinikal Sains (Jurnal Analis Kesehatan) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Biomedika Jurnal Psikohumanika Budimas : Jurnal Pengabdian Masyarakat Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Kesehatan Tambusai Journal of Indonesian Medical Laboratory and Science (JoIMedLabS) Jurnal Pengabdian Mandiri Conference on Innovation in Health, Accounting, and Management Sciences Proceeding Jurnal Medicare Health Care : Journal of Community Service
Gunawan, Lucia Sincu
Fakultas Ilmu Kesehatan, Universitas Setia Budi, Jl. Letjen Sutoyo,Mojosongo, Surakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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PERBEDAAN KADAR HEMOGLOBIN (Hb) dan INDEKS ERITROSIT SEBELUM DAN SESUDAH MENGONSUMSI TABLET TAMBAH DARAH (TTD) PADA REMAJA PUTRI ANEMIA Rumeyda Chitra Puspita Puspita; Lucia Sincu Gunawan; Dhiana Puspitasari; Adelya Althaf Anggraini
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v13i2.6817

Abstract

Anemia is a global health problem frequently affecting adolescent girls, characterized by hemoglobin levels below normal. The main causes of anemia include inadequate iron intake and unhealthy lifestyle habits. This study aimed to determine the differences in hemoglobin levels and erythrocyte indices (MCV, MCH, MCHC) before and after consuming iron tablets among anemic adolescent girls. This research employed a quasi-experimental design with a one-group pretest-posttest conducted in April–May 2025. The subjects were 28 female students of Setia Budi University selected using purposive sampling. Data collection included laboratory examination of hemoglobin and erythrocyte indices as well as questionnaire responses. The intervention consisted of daily iron tablet supplementation for 20 days. The results showed that the median hemoglobin level increased from 11.1 g/dL (10.3–11.7) to 11.6 g/dL (10.8–12.1). The Wilcoxon Signed Rank Test indicated a significant difference in hemoglobin levels before and after supplementation (p < 0.001). Erythrocyte indices also improved, with mean MCV increasing from 74.03 ± 5.9 fL to 74.52 ± 7.6 fL, MCH from 22.76 ± 2.5 pg to 25.21 ± 3.1 pg, and MCHC from 30.77 ± 1.3% to 33.35 ± 2.4%. The paired t-test confirmed significant differences in MCV, MCH, and MCHC before and after iron tablet consumption. There were significant differences in hemoglobin levels and erythrocyte indices before and after iron tablet supplementation among anemic adolescent girls.
Suplementasi Asam Folat Meningkatkan Kadar Hemoglobin dan Indeks Eritrosit pada Wanita Usia Subur Fatikhah Intan Maharani; Lucia Sincu Gunawan; Rumeyda Chitra Puspita
MEDIA ILMU KESEHATAN Vol 14 No 3 (2025): Media Ilmu Kesehatan
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

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Abstract

Background: Women of reproductive age (WORA) are a group prone to anemia, one of which is due to folic acid deficiency which plays a role in DNA synthesis and erythrocyte formation.Objective: The study aimed to determine the differences in hemoglobin and erythrocyte indices among women of reproductive age with folic acid supplementation.Methods: A quasi-experimental research on the design of one group pretest-posttest on 67 female students of Setia Budi University was conducted in October 2024–February 2025. Respondents aged 18-25 years, selected by purposive sampling, were given folic acid tablet supplement (Folavit® 0.4 mg) twice daily for 14 days. Primary data were obtained from hematology examinations taken before after the intervention with a hematology analyzer, showing changes in hemoglobin and erythrocyte indices. Test Wilcoxon Signed Rank to analyze the data.Results: The results showed significant increases in hemoglobin from 12.96 ± 0.93 g/dL to 13.53 ± 0.91 g/dL (p<0.001), MCV from 85.54 ± 4.36 to 86.39 ± 4.14 (p<0.001), MCH from 27.61 ± 2.12 pg to 28.20 ± 2.06 pg (p<0.001), and MCHC from 33.05 ± 1.62% to 33.74 ± 1.56% (p<0.001) after folic acid supplementation.Conclusion: Folic acid supplementation increased hematological status and may serve as a preventive strategy against anemia in women of reproductive age.
Co-Authors Adelya Althaf Anggraini Afif Afghohani, Afif Alex Jekson Tukira Alfiana, Ina Ana Ines Kisnaini Anak Agung Gede Sugianthara Anita Nurfaiz Contriwati Indricuan Dewi, Yulia Ratna Dhiana Puspitasari Diah Pramudianti Dwi Nur Indah Sari Dwi Nur Indah Sari, Dwi Nur Indah Edy Prasetya Edy Prasetya Emma, Ismawatie Estu Sami Asih Fatikhah Intan Maharani Hafizah, Dila Auli Ilham Kuncahyo, Ilham Irma Ningsih Yuvita Fallo Ismawatie, Emma Iswandi Iswandi KARSANTO, NARINDRO Kartinah Wiryosoenjoyo Khairunnisa, Salma Shabrina Khofifah Tasha Widya Martha Kunti Dewi Saraswati Livrança, Expedito José Oliveira Mactildis Yosefeni Mariandini Talnoni Mahardira Dewantara Mahayana, Argoto Narimo Narimo, Narimo Nur Hidayati Prasasti, Anin Prilya Shanty Andrianie Puspita, Rumeyda Chitra Putri, Hana Maylinda Rahmawati, Juvita Tri Rany Reynaldy Reny Pratiwi Rina A. Sidharta RM Narindro Karsanto Rosita Yuniati, Rosita Rumeyda Chitra Puspita Rumeyda Chitra Puspita Rumeyda Chitra Puspita Rumeyda Chitra Puspita Puspita Soebiyanto, Soebiyanto Stevanus Zulkarnaen Wijaya Wara Sugiyarmasto Sugiyarmasto, Sugiyarmasto Sumardiyono Sumardiyono Sunardi Sunardi Sutopo, Salsa Tri Aprilia Putri Wahyuningsih, Sandra Tri Wiryosoendjoyo, Kartinah Yustinus Joko Dwi Nugroho Zefika Lutfi Ivana