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All Journal e-CliniC Jurnal MIPA PHARMACON JURNAL LPPM BIDANG SAINS DAN TEKNOLOGI Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ The Studies of Social Sciences Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Jurnal Lentera Farma Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Gayatri Citraningtyas
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Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Pengaruh Intervensi Pill Box terhadap Kepatuhan Minum Obat dan Luaran Klinis pada Pasien Lanjut Usia dengan Penyakit Hipertensi Mpila, Deby A.; Wiyono, Weny I.; Citraningtyas, Gayatri
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58383

Abstract

Abstract: The prevalence of hypertension increases with age. One of the keys to effective hypertension therapy is adherence. There are several ways to improve medication adherence, one of which is by using pill boxes. This study aimed to determine the effect of pill box intervention on the level of medication adherence and clinical outcomes among geriatric patients with hypertension at the Imanuel Clinic Manado. This was an experimental analytical study with randomized controlled trial (RCT) using pre-test and post-test control group design. Data were obtained prospectively in the period of July to August 2024 with a sample size of 60 respondents (30 intervention and 30 control). The level of adherence was assessed using MMAS-8 questionnaire and data of clinical outcomes were obtained from systolic and diastolic blood pressures. The measurement was preceded before and after treatment. The data were analyzed statistically using bivariate analysis. A p-value of <0.05 was considered statistically significant. The result showed that the pill box intervention had a significant effect on the level of medication adherence (p=0.001). Meanwhile, there was no effect of pill box intervention on clinical outcomes (p=1.000) because as many as 60 patients (100%) had reached the target blood pressure before and after treatment. In conclusion, using pill box can increase medication adherence in geriatric patients with hypertensive disease. Keywords: geriatric patients; hypertension; pill box; medication adherence; clinical outcome    Abstrak: Prevalensi hipertensi semakin meningkat seiring bertambahnya usia. Salah satu kunci keberhasilan terapi hipertensi ialah kepatuhan. Terdapat beberapa cara meningkatkan kepatuhan minum obat, salah satunya dengan menggunakan pill box. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian intervensi pill box terhadap tingkat kepatuhan minum obat dan luaran klinis pada pasien lanjut usia (lansia) dengan penyakit hipertensi di Klinik Imanuel Manado. Penelitian bersifat analitik eksperimental dengan jenis penelitian randomized controlled trial (RCT) dengan desain pre-test dan post-test control group. Data diperoleh secara prospektif pada periode Juni–Agustus 2024 dengan jumlah sampel sebanyak 60 pasien (30 pasien intervensi dan 30 pasien kontrol). Kepatuhan minum obat diukur menggunakan kuesioner MMAS-8 dan luaran klinis diukur berdasarkan tekanan darah sistolik dan diastolik. Pengukuran dilakukan sebelum dan setelah perlakuan. Data dianalisis secara statistik menggunakan analisis bivariat. Nilai p<0,05 dianggap bermakna secara statistik. Hasil penelitian menunjukkan bahwa intervensi pill box memberikan pengaruh bermakna terhadap kepatuhan minum obat (p=0,001). Tidak terdapat pengaruh intervensi pill box terhadap luaran klinis (p=1,000), karena sebanyak 60 pasien (100%) telah mencapai target tekanan darah baik sebelum mapun sesudah perlakuan. Simpulan penelitian ialah penggunaan pill box dapat meningkatkan kepatuhan pasien lanjut usia untuk mengonsumsi obat antihipertensi. Kata kunci: lanjut usia; hipertensi; pill box; kepatuhan minum obat; luaran klinis
Co-Authors Abbas, Syahruni Ramdhani Adilang, Claudia Adilang, Claudia L. Adithya Yudistira Agnes, Agatha Agow, Mikhael C. Alfamega Pinasang Angkoauwa, Leydia Angkow, Leydia Ardiany, Wahyu M. Ary Pratama Samosir Axl Laurens Lukas Windah Ayhuan, Jeckson Benawan, Steyfan Chalvy Wowiling Christina Pangemanan Christy Eunike Launa Kawuwung Cindy R. Rotulung Clara A. Sengke Datu, Olvie S. DEBY AFRIANI MPILA Defny S. Wewengkang, Defny S. Edi, Hosea Jaya Elda F Luawo, Essing, Jacklien Deswita Esti Santi Sigar Eva B. Mare Fatimawali . Febrylia T. Pongsitammu Frenly Wehantouw Fridly Manawan Gagola, Mariana Cristi Ayu Gerald E. Rundengan Gerald Rundengan Heri Wijaya, Heri Herny E.I. Simbala Hosea Jaya Edy Hutahaean, Amsaline Imam Jayanto Jainer Pasca Siampa Jayanto, Imam Jemmy Abidjulu Jonathan Tumiwa Juan Sebastian Lambey Juita S. D. Tatara Juliawati, Ni Waya Mega Juliawati, Ni Wayan M. Kalalo, Tekla Karlah Frylina Kantu Karlah L. R. Mansauda Kaunang, Venesya Kaunang, Venesya Natalia Putri Kawulusan, Kerin Sophia Amelia Clairent Kawuwung, Christy Eunike Launa Kissi Parengkuan Laleno, Ellysa N. Lambey, Juan Sebastian Landy A. Ch Lolaen Lestari, Monica D. Lestari, Monica Dewi Lidya Valda Mamoto Liling, Yessi Lily Ranti Goenawi Maalangen, Tiansi Mahendra Kusuma Nugraha Majid, Nurul Majid, Nurul S Malara, Jeril Riski Malota, Fiske W E Marhaeni Chintami Andries Marhaenus Rumondor Maria Efrani Tengor Mariana Gagola Max R J Runtuwene Max R.J. Runtuwene Max Revolta John Runtuwene Meilani Jayanti Miranty H Kadji Monalisa Karinda Monibala, Tiarma Mulalinda, Rafel D. Muzdhalifah, Balqis Nadhirah J. Mokoginta Nalang, Amelia Nangaro, Alfred Nangaro, Jesica Novel Kojong Nurjana Usman Nurnisa Mayningsih M S Ipa Onibala, Putri Marfanti Paulina yamlean Pelealu, Nancy Poddar, Sandeep Purwoko, Agus Randy Tampa’i Rekanita Waney Rumondor, Erladys M. Rundengan, Gerald Rundengan, Gerald Edward Ruru, Ranny Inggrid Sari, Elmi Sari, Elmi N. Septi C. F. Hitto Sherina H. Karauwan Siampa, Jainer P Siampa, Jainer Pasca Siti Suhartini Sri Sudewi, Sri Sukandi, Gabrilia Sukandi, Gabrilia P. C. Tatara, Juita S. D. Tawalujan, Wulan P. Tengor, Maria Efrani Tiarma Tiarma Tulung, Gerald Tulung, Gerald N. P. Tumbel, Zefania M. Weny I Wiyono Weny Wiyono Wewengkang, Defny Widiastuti, Priskha Widya Astuty Lolo, Widya Astuty Widya Selawa Windah, Axl Laurens Lukas Wiyono, Weny I. Wiyono, Weny Indayany