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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Jurnal BALIRESO Batoboh : Jurnal Pengabdian Pada Masyarakat FITOFARMAKA: Jurnal Ilmiah Farmasi Jurnal Review Pendidikan dan Pengajaran (JRPP) Journal of Experimental and Clinical Pharmacy (JECP) Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Indonesia Celebes Journal of Community Services Journal of Pharmaceuticals and Natural Sciences Makassar Natural Product Journal MPSJ

Ahmad, Aktsar Roskiana

Fakultas Farmasi Universitas Muslim Indonesia

Author-ID : 2485575

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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PENETAPAN KADAR FLAVONOID TOTAL DARI EKSTRAK ETANOLIK DAUN BENALU MANGGA (Dendrophthoe pentandra L. Miq) Rizki Yulianti R; A. Amaliah Dahlia; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 1, No 1 (2014): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Mistletoes (Dendrophthoe pentandra L. Miq) is one of the medicine plant which used traditionally to remedy the various of disease. Empirically, communities used mistletoes leaves as cough, tonsillitis, measles, cancer, diuretic, and pain relievers. This research is aimed to determine total flavonoid content in extract of mistletoes leaves (Dendrophthoe pentandra L. Miq). Extraction has done with Thin Layer Cromathography (KLT) method to determine active content which in sample. Analysis of chemistry content in ethanolic extract of mistletoes leaves show are flavonoid content. Content of total flavonoid with Chang et al., 2002 method using UV-Vis spectrophotometry at a wavelength of 440 nm. From this research result 39.713 g ethanolic extract with percent of extract rendamen is 6.109% from 650 g dry powder of mistletoes leaves. The results of total flavonoid of ethanolic extract of mistletoes leaves is 2.48% calculated as quercetin.

STUDI KOMPARASI KADAR FLAVONOID TOTAL PADA BUNGA ROSELLA MERAH (Hibiscus sabdariffa L.) ASAL KABUPATEN LUWU UTARA PROVINSI SULAWESI SELATAN DAN KABUPATEN KEDIRI PROVINSI JAWA TIMUR Saida I. Suradji; Ahmad Najib; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Red Roselle (Hibiscus sabdariffa L.) is a medicinal plant used by the public as drugs. This plant is efficacious because one contains chemical constituents are flavonoids. Comparative Study of total Flavonoid content in red Roselle (Hibiscus sabdariffa L.) from North Luwu district of South Sulawesi province and the province of East Java Kediri district has done. The aim of study to determine of total flavonoid content in Kediri regency and district of North Luwu using a spectrophotometer. Extraction is done by maceration method using 96% ethanol. Phytochemical screening using the color reaction identification and determine content of Colorimetric method using UV-Vis spectrophotometry at the maximum wavelength of 417 nm. Meanwhile the yield extract red Rosellafrom Kediri (sample I) 12.703% and red Rosella from north Luwu (sample II) 10.44%. Test phytochemical to sample I and sample II positive containing Flavonoids. Test total Flavonoid content to sample I is 0.02816% and sample II is 0.2075%.

PENGUJIAN AKTIVITAS ANTIOKIDAN EKSTRAK TERPURIFIKASI DAUN TEH HIJAU DAN JATI BELANDA Abd. Malik; Aktsar Roskiana Ahmad; Ahmad Najib
Jurnal Fitofarmaka Indonesia Vol 4, No 2 (2017): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Teh hijau memiliki nama spesies Camellia sinensis (L.) Kuntze, family Theaceae dan Jati belanda (Guazuma ulmifolia Lam.) termasuk kedalam family sterculiaceae. Ekstrakse dengan metode maserasi termodifikasi microwave dengan pelarut air. Purifikasi ekstrak dengan menggunakan pelarut dengan tingkat kepolaran yang berbeda-beda dimulai dengan petroleum eter, kloroform, etil asetat dan metanol. Pengujian aktivitas antioksidan dengan metode peredaman radikal DPPH. Hasil penelitian dipeoleh rendamen ekstrak terpurifikasi ekstrak teh hijau 13,33 % dan jati belanda 46,66 %.Pengujian antioksidan menunjukkan nilai IC50 jati belanda yaitu 10,13 ppm, lebih besar dibandingkan teh hijau yaitu 31,13 %.

UJI AKTIVITAS LARVASIDA EKSTRAK DAUN JARAK KEPYAR (Ricinus communis L.) TERHADAP LARVA NYAMUK Aedes aegypti Wahyu Wira Utami; Aktsar Roskiana Ahmad; Abd. Malik
Jurnal Fitofarmaka Indonesia Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Castor Plant (Ricinus communis L.) belongs to Euphorbiaceae family. In medicine has been used as antioxidant, antihistaminic, antifertility, antimicrobial, antidiabetic, antiinflammatory, antipyretic, and it has activities to larvacidal, molluscicidal and insecticidal. The aim of this study was to determine the level of mosquito larva (Aedes aegypti) mortality after giving of ethanolic extract showed with LC50. Extract obtained by maceration method, rendamen ethanolic extract obtained as much as 6.073%. This research uses 110 instar, III larvae of mosquito (Aedes aegypti), divided into test solution are made with 3 concentrations (10 µg/mL, 100 µg/mL, 1000 µg/mL), positive control using Abate and negative control using water. Observations were made after 24 hours of treatment. Toxicity test results shows ethanolic extract is an extract that is active as Larvacidal showed LC50 as much as 138,995 ± 1,5 µg/mL < 1000 µg/mL. Based on qualitative testing of the chemical component using TLC method known ethanolic extract of Castor Plant (Ricinus communis L.) leaves contain alcaloids, saponins and flavonoids.

UJI AKTIVITAS LARVASIDA EKSTRAK TERPURIFIKASI DAGING BUAH MIMBA (Azadirachta indica A. Juss.) ASAL PULAU LOMBOK TERHADAP Aedes aegypti Selpida Handayani; Aktsar Roskiana A.; Umi K. R. Karim
As-Syifaa Jurnal Farmasi Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Neem (Azadirachta indica A.Juss.) Is a plant that has medicinal benefits as malaria, antitukak stomach and is also can used as natural insecticides, fungicides, larvicides and antifertility. This Research aims to know the mortality rate of larvae of Aedes aegypti with LC50 values indicated. Neem fruit plucked from a tree lombok island.neem. Extracts obtained by maceration solvent with the masceration methanol. Retrieved rendamen extract as much as 25,17%, then purified with n-hexane solvent. Larvasida test used 180 larvae of Aedes aegypti first instar III. Test solutions were made in 4 concentration, positive control using powder Abate® (Themephos), and a negative control. Observations were made after 24 hours of treatment . Aedes aegypti larval mortality analyzed with probid analysis to know LC50 and obtained phytochemical components contained in the methanol extracts were saponins and tannins. LC50 obtained from the methanol extract of neem fruit flesh is 1817,18 ± 1,075 µg/ml. This shows the methanol extract of neem fruit flesh (Azadirachta indica A.Juss.) Does not have the effect toxicity against larvae of Aedes aegypti indicated by LC50 > 1000 ppm. Keywords: Flesh neem, Azadirachta indica A. Juss., Aedes aegypti, LC50.

Kadar Fenolik Dan Flavonoid Total Dalam Ekstrak Metanol Daun Cemba (Acacia rugata (Lam.) Fawc. Rendle) Andi Amaliah Dahlia; Nur Qadri Amima; Aulya Rachma Arum; Rezki Amriati Syarif; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 9, No 1 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i1.808

This study aims to determine and compare the phenolic and flavonoid content of methanol extract in Acacia rugata (Lam.) Fawc. Rendle leaves using UV-Vis spechtrophotometer and TLC-densitometry. The Acacia rugata (Lam.) Fawc. Rendle extracted by using maceration applied sonicator. The quantitative analysis measured by UV-Vis spectrophotometer at wavelength 430 nm. The TLC–densitometry performed at wavelength of 254 nm and quercetin was as a standard. The results showed that the phenolic total showed 0.506 gGAE/g extract and 0.879 gGAE/g extract. The flavonoid total showed 0.44 gQE/g extract and 0.73 gQE/mg extract respectively.

UJI TOKSISITAS ANTIKANKER DAUN BELUNTAS (Plucea indica) Aktsar Roskiana Ahmad
As-Syifaa Jurnal Farmasi Vol 1, No 2 (2009): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v1i2.99

ToxicityTest anticancer of Beluntas Folium (Plucea indica). The research was mainly to give information of anticancer activity of beluntas. Takeing sample in in Makassar city with interview public figure. Toxicity test with Brine Shrimp Lethality Test (BST) method and used negatif control sea water. The result, beluntas haven anticancer activity and LC50 is 44,31 ± 12,65 mg/ml.Keyword : Anticancer, Plucea indica

Penetapan Kadar Fenolik dan Flavonoid Total Ekstrak Metanol Buah dan Daun Patikala (Etlingera elatior (Jack) R.M.SM) Ahmad, Aktsar Roskiana; Juwita, Juwita; Ratulangi, Siti Afrianty Daniya
Pharmaceutical Sciences and Research Vol. 2, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Fruit and leaves of patikala (Etlingera elatior (Jack) R.M.Sm), is a traditional medicinal plants used by people to treat various diseases. The purpose of this study was to determine the total phenolic and flavonoid compounds of E. elatior fruits and leaves extracts. We extracted dried fruits and leaves samples by maceration method using methanol. Qualitative analysis of chemical compounds with certain eluent was done using Thin Layer Chromatography (TLC) to determine the group of active compounds in the extract. The amount of phenolic compounds in the sample was determined by the colorimetric method at a maximum wavelength of 744.8 nm and flavonoid at 431 nm. The results showed that the methanol extract rendemen was 1.93% for fruit and 5.17% for leaf with a total phenolic content of the fruit was 2.29 mgGAE/g b/b extract and leaf was 6.29 mgGAE/g b/b extract. And total flavonoid content of the fruit was 1.7761 % mg Quercetin/g b/b extract and leaf was 5.45 mgQE/g b/b extract.

Uji Aktivitas Antioksidan Ekstrak Metanol Bunga dan Daun Patikala (Etlingera elatior (Jack) R.M.Sm) Menggunakan Metode DPPH Handayani, Virsa; Ahmad, Aktsar Roskiana; Sudir, Miswati
Pharmaceutical Sciences and Research Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Patikala (Etlingera elatior (Jack) R.M.Sm) is a plant of the Zingiberaceae family. Patikala (E. elatior (Jack) R.M.Sm) have bioactive compounds are flavonoids that act as antioxidants. The purpose of this study was to measure free radical activity in the methanol extract of the fruit and leaves Patikala (E. elatior (Jack) R.M.Sm). Extraction of flowers and leaf samples by maceration method using methanol. Qualitative analysis of chemical compounds with certain eluent using Thin Layer Chromatography (TLC) to determine the group of active compounds in the extract. Antioxidant activity assay using the immersion method of DPPH (1,1-Diphenyl-2-picryl Hidrazil) measured absorption at a wavelength of 517 nm and compared with the power of antioxidant quersetin. The results showed that the methanol extract rendemen is at 1.935% for flowers and leaves at 5.17%. Antioxidant activity of the methanol extract of the flowers patikala (E. elatior (Jack) R.M.Sm) have low antioxidant activity with the value IC50 101.84 mg / mL and methanol extracts of leaves Patikala (E. elatior (Jack) R.MSm) have strong antioxidant activity with value IC50 30,65 mg / mL. This potential is lower than that of quercetin IC50 value of 5.35 mg / mL.

The Effect of Extraction Method on Catechin Levels in Green Tea (Camellia sinensis L.) Extract by TLC-Densitometric Aktsar Roskiana Ahmad; Bahria Bahria; Harti Widiastuti
Jurnal Fitofarmaka Indonesia Vol 9, No 3 (2022): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i3.915

Green tea (Camellia sinensis L.) is one of the most widely used plants in Indonesia. Green tea (Camellia sinensis L.) is rich in catechins which have many benefits including antioxidants, anticancer, can reduce stress, and reduce cholesterol levels in the blood. This study aims to determine the levels of catechins in Green Tea (Camellia sinensis L.) extract with various extraction methods. Each sample was extracted by maceration, microwave and infusion using aquadest solvent and the extract obtained in Freeze Drying. Qualitative analysis using 1% FeCl3 reagent, positive catechins are indicated by a color change to blackish blue and quantitative analysis using TLC-Densitometry. The results showed the catechin content of the extract by maceration method was 331 mg/g

Co-Authors A Amaliah Dahlia ABD. MALIK Abd. Malik Abdul Malik Abdul Rasyid, Faradiba Abdullah Mahmud Ahmad Najib Amima, Nur Qadri Anak Agung Istri Sri Wiadnyani Andi Afifah Amdar Anisa, Rianti Arif Rahman Asni Amin Asriani Suhaenah Aulya Rachma Arum Bahria Bahria Bayu Putra, Bayu Dwiyanti Puspitasari Fadlina Chany Saputri Fadliyah, Nurfadhilah Firdha Sari Firdha Sari, Firdha Hamidu, La Harti Widiastuti Harti Widiastuti Hasnaeni hasnaeni, Hasnaeni Hidayah, Andi Nurul Annisa HM, Nur Rahmah I Ketut Suada Juwita Juwita Juwita Juwita, Juwita Miswati Sudir Miswati Sudir Miswati Sudir, Miswati Muhajir Muhajir Murfat, Zulkifli Niken Pratiwi Liambo Niza, Nabila Ikhwanun Nur Qadri Amima Nur Rezky Khairun Nisaa Nurhawa Vitalia Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif, Rezki Amriati Risda Waris Rizki Yulianti R Rizqi Nur Azizah S, Aulya Rachma Arum Saida I. Suradji Selpida Handayani Siti Afrianty Daniya Ratulangi Siti Afrianty Daniya Ratulangi, Siti Afrianty Daniya Tiara Katulista Islamia Tulnisa, Hijeria Umi K. R. Karim Virsa Handayani Wahyu Wira Utami

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