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All Journal ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Journal of Dentomaxillofacial Science Journal of Indonesian Dental Association Journals of Ners Community Media Karya Kesehatan Padjadjaran Journal of Dental Researchers and Students Interdental Jurnal Kedokteran Gigi (IJKG) Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) Odonto dental journal
Indra Hadikrishna
Department Of Oral And Maxillofacial Surgery, Faculty Of Dentistry, Padjadjaran University, Bandung Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Energy Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Characteristics of Fibrous Dysplasia at Oral and Maxillofacial Surgery Department RSUP Dr. Hasan Sadikin: A 6-year Retrospective Study Prestya, Pebrian Diki; Hadikrishna, Indra; Sylvyana, Melita; Adiantoro, Seto; Rizki, Kiki Achmad
Odonto : Dental Journal Vol 11, No 2 (2024): December 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.2.188-193

Abstract

Introduction: Oral and Maxillofacial surgeon encounter challenges diagnose fibrous dysplasia due to wide variety of investigations required, such as radiographic, histological, and clinical examinations. Fibrous dysplasia typically manifests at first or second decade of life; these lesions tend to form at young age and cease when somatic growth completed. Aim: The aim of this study understanding the characteristics of fibrous dysplasia in patients treated from 2017 to 2023 at Department of Oral and Maxillofacial Surgery Hasan Sadikin Hospital. Research Method: Design of this study is a qualitative descriptive study with retrospective using medical record data of patients diagnosed as fibrous dysplasia at Department of Oral and Maxillofacial Surgery of Hasan Sadikin General Hospital in January 2017 — March 2023. Variables in this study include age, gender, anatomical location at craniofacial area, histopathological diagnosis, and treatment provided. Results:  This study showed Characteristics of fibrous dysplasia patients results by sex being highest in Women as many as 6 patients (54.54%), by age indicating the most age at 17-25 years old as 5 patients (45.45%). In addition, the highest prevalence based on histopathological diagnosis is monostotic type, which is 8 patients (72.72%) and three patients (27.27%) with polyostotic type. Based on the anatomical location the most at maxilla region, which is 7 patients, which is 5 (45,45%) patients at left maxilla region and 2 (18,18%) patients at right maxilla region. In addition, based on treatment the most was reshaping with 7 patients (63.63%).Conclusion: The most prevalent characteristic of patients with fibrous dysplasia is woman and by age indicating the most age at 17-25 years old. According to anatomical location the most is maxilla region. Monostotic fibrous dysplasia the most diagnose and the most prevalent treatmet is reshaping, which is the best therapy for of fibrous dysplasia.
Tatalaksana impaksi gigi molar ketiga mandibula dengan prosedur coronectomy: rapid review Septiani, Tiara Ika; Yuza, Abel Tasman; Hadikrishna, Indra
Padjadjaran Journal of Dental Researchers and Students Vol 8, No 3 (2024): October 2024
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v8i3.56773

Abstract

ABSTRAK Pendahuluan: Pencabutan impaksi gigi molar ketiga sering kali mengalami komplikasi. Komplikasi pasca pencabutan gigi molar ketiga diantaranya rasa nyeri, dry socket, dan cedera saraf alveolaris inferior. Cedera saraf alveolaris inferior adalah komplikasi khas dari pencabutan gigi molar ketiga rahang bawah. Coronectomy merupakan salah satu tindakan yang digunakan untuk perawatan impaksi gigi molar ketiga. Coronectomy dianggap sebagai prosedur yang baik dalam mengurangi terjadi cedera pada inferior alveolar nerve (IAN). Tujuan penelitian ini untuk mengetahui keuntungan dan kerugian dari perawatan impaksi gigi molar tiga rahang bawah dengan prosedur coronectomy. Metode: Dalam penelitian ini peneliti menggunakan metode rapid review yang mengacu pada panduan Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA). Pencarian artikel secara elektronik dilakukan pada tiga basis data elektronik yaitu National Library of Medicine (Medline/Pubmed), Cochrane Library, dan Sciencedirect. Hasil: Dari enam artikel yang ditinjau, dua artikel menilai perbandingan antara odontectomy dan coronectomy menunjukan bahwa coronectomy lebih baik dalam mengurangi terjadinya komplikasi pasca operasi. Empat artikel lainnya menunjukan tidak ada atau sedikit laporan kasus terjadinya cedera saraf. Hasil lain dari coronectomy seperti nyeri, infeksi, osteitis alveolar sama atau lebih rendah dibandingkan dengan odontectomy. Hasil terjadinya migrasi akar setelah tindakan coronectomy cukup tinggi dan hasil dari gigi yang memerlukan operasi ulang lebih rendah, untuk jangka waktu follow-up bervariasi setiap artikelnya. Simpulan: Coronectomy diindikasikan jika gigi molar ketiga mandibula dekat dengan saraf alveolaris inferior dan coronectomy terbukti mengurangi cedera IAN dan dry socket.KATA KUNCI: coronectomy, impaksi gigi molar ketiga, cedera saraf alveolar inferior, rapid review.The management of impacted mandibular third molars with coronectomy procedure: rapid reviewABSTRACT Introduction: The extraction of impacted third molar teeth often experiences complications. Post-extraction complications of third molar teeth include pain, dry socket, and inferior alveolar nerve injury. Inferior alveolar nerve injury is a typical complication of extraction of mandibular third molars. Coronectomy is an alternative procedure used to treat impacted third molars. Coronectomy is considered a good procedure in reducing the injury to the inferior alveolar nerve (IAN). The purpose of this study was to determine the advantages and disadvantages of treating impacted mandibular third molars with coronectomy procedures. Methods: In this study, the researchers used a rapid review method that refers to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Electronic search of articles was carried out on three electronic databases, namely the National Library of Medicine (Medline / PubMed), Cochrane Library, and Sciencedirect. Results: Of the 6 articles reviewed, 2 articles assessing the comparison between extraction and coronectomy showed that coronectomy was better in reducing the occurrence of complications. The other 4 articles have no or few case reports of neurological disorders. Other outcomes of coronectomy such as pain, infection, alveolar osteitis was equal or lower than those of complete extraction. The results of root migration after coronectomy were quite high and the results of teeth requiring reoperation were lower, with follow-up periods varying between articles. Conclusion: Coronectomy is indicated if the mandibular third molars are close to the inferior alveolar nerve and coronectomy has been shown to reduce the incidence of IAN and dry socket injuries.KEY WORDS: Coronectomy, impacted third molars, injury inferior alveolar nerve, rapid review.
Prevalensi Dan Terapi Anomali Vaskular Pada Rongga Mulut Di Departemen Bedah Mulut Dan Maksilofasial Hudiworo K.D, Bambang; Hadikrishna, Indra; Marwansyah Oli’I, Eka
Journals of Ners Community Vol 14 No 1 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.2527

Abstract

Anomali vaskular adalah kelainan kongenital dan abnormal neonatal bersifat benign lesions serta dapat terjadi di kepala-leher pada usia anak-anak dan dewasa dengan regio yang sering terjadi di lidah,bibir,mukosa bukal,dan palatum. Anomali vaskular diklasifikasikan menjadi dua klasifikasi utama,yaitu tumor vaskular dan malformasi vaskular. Penelitian dilakukan dengan studi deskriptif retrospektif dan dilaksanakan di Rumah Sakit Umum Pusat dr. Hasan Sadikin. Kriteria inklusi penelitian yaitu rekam medis pasien terdiagnosa anomali vaskular periode Januari 2019–Desember 2020. Terdapat 38 kasus anomali vaskular pada rongga mulut yang dilakukan perawatan di Kelompok Staff Medis (KSM) Bedah Mulut dan Maksilofasial RSHS. Kelompok mayoritas pasien berusia 13-24 tahun sebanyak 21 orang. Pasien perempuan adalah golongan yang sering berobat di RSHS yaitu sebanyak 27 orang. Tipe anomali vaskular yang umum terjadi adalah vena malformasi berjumlah 18 kasus atau 47% dari seluruh total kasus. Regio yang sering terjadi adalah di labii inferior superior berjumlah 14 kasus atau 37%. Terapi yang sering diberikan adalah injeksi scleroting agent dan eksisi sebanyak 34 kasus. Anomali vaskular rongga mulut adalah kelainan yang sering ditemukan di KSM Bedah Mulut dan Maksilofasial RSHS dengan terapi yang umum diberikan adalah injeksi scleroting agent dengan tujuan untuk minimalisir komplikasi setelah tindakan operasi.
Craniofacial Fibrous Dysplasia in Pediatric Patients with McCune-Albright Syndrome: A Scoping Review Salsabila, Anisah Rifda; Yusuf, Harmas Yazid; Hadikrishna, Indra
Journal of Indonesian Dental Association Vol 8 No 1 (2025): May
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v8i1.1286

Abstract

Pendahuluan: Fibrous dysplasia (FD) adalah kelainan tulang langka non-neoplastik yang dikarakterisasikan dengan proliferasi berlebih pada proses pembentukan tulang oleh sel mesenkim. FD dapat timbul sebagai salah satu gejala klinis dari sindroma McCune-Albright (MAS). MAS memiliki triad gejala klinis khas yang terdiri dari FD, makula café-au-lait, dan hiperfungsi endokrinopati. FD dan MAS disebabkan oleh mutasi genetik post-zigotik, sehingga pasien akan lahir dengan penyakit FD. Penelitian ini bertujuan untuk memetakan dan menganalisis pengaruh gejala klinis lain dari MAS terhadap lesi FD kraniofasial pada pasien anak. Metode: Penelitian dilaksanakan menggunakan metode scoping review. Pencarian artikel dilakukan pada database Scopus dan PubMed. Kriteria inklusi: artikel yang membahas mengenai karakteristik lesi FD kraniofasial yang berkaitan dengan MAS pada pasien anak, dipublikasikan dalam jangka tahun 2016-2023, dipublikasikan melalui jurnal internasional, full text, dan free article. Penyaringan sumber literatur dilaksanakan sesuai dengan protokol PRISMA-ScR. Hasil: Delapan artikel ditetapkan sebagai kriteria inklusi. Pengaruh dari uncontrolled GH excess terhadap patogenesis lesi FD dibahas pada seluruh artikel, diantaranya adalah meningkatnya risiko gangguan penglihatan/pendengaran (tujuh artikel), tampilan makrosefali (lima artikel), meningkatnya risiko regrowth pasca operasi (empat artikel), ekspansi lesi FD (empat artikel), dan meningkatnya morbiditas lesi FD (satu artikel). Pembahasan mengenai PP serta koeksistensinya dengan gejala uncontrolled GH excess dibahas pada satu artikel. Hipofosfatemia dibahas pada lima artikel. Simpulan: GH excess dan PP merupakan jenis hiperfungsi endokrinopati yang dapat memperparah patogenesis dan gejala klinis lesi FD. Pada pasien MAS dengan jumlah (skeletal burden) lesi FD yang masif kondisi hipofosfatemia akan meningkatkan risiko fraktur tulang dan rasa nyeri pada lesi FD.
Korelasi antara kadar D-dimer plasma dengan derajat keparahan trauma maksilofasial berdasarkan Maxillofacial Injury Severity Score (MFISS) pada penderita cedera kepala ringan: Studi Cross-Sectional Saleh, Ardian; Syamsudin, Endang; Hadikrishna, Indra; Prihatni, Delita
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 36, No 3 (2024): Desember 2024
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v36i3.58689

Abstract

Pendahuluan: Penderita trauma maksilofasial berisiko mengalami cedera kepala karena letaknya berdekatan dengan kranium. D-dimer plasma merupakan produk akhir pemecahan bekuan darah yang dapat diukur melalui sampel darah, dan berperan sebagai faktor prognostik pada cedera kepala. Maxillofacial Injury Severity Score (MFISS) adalah skoring terbaru untuk menilai derajat keparahan trauma maksilofasial berdasarkan tiga skor cedera tertinggi. Trauma maksilofasial sering disertai cedera kepala dengan peningkatan kadar D-dimer. Penelitian ini bertujuan menganalisis hubungan kadar D-dimer plasma dengan derajat keparahan trauma maksilofasial berdasarkan MFISS sebagai pertimbangan prognostik. Metode: Jenis penelitian adalah kuantitatif cross-sectional. Penelitian dilakukan pada 38 subjek berusia >18 tahun dengan trauma maksilofasial disertai cedera kepala ringan dalam fase 2–24 jam di IGD RS Hasan Sadikin Bandung. Derajat keparahan trauma maksilofasial dinilai menggunakan MFISS, dan cedera kepala ringan dinilai berdasarkan GCS. Sampel darah diambil untuk pemeriksaan D-dimer plasma. Data dianalisis menggunakan uji Spearman Rank. Hasil: Rerata kadar D-dimer plasma sebesar 3,42 pg/dL (p=0,001), dan rerata skor MFISS 6,89 ± 1,91 (p=0,022). Terdapat korelasi positif moderat antara kadar D-dimer dengan skor MFISS (r=0,512). Simpulan: Terdapat peningkatan kadar D-dimer plasma pada trauma maksilofasial disertai cedera kepala ringan. Ditemukan hubungan signifikan antara kadar D-dimer dengan tingkat keparahan trauma maksilofasial berdasarkan MFISS. Correlation between plasma D-dimer levels and the severity of maxillofacial trauma based on the maxillofacial injury severity score (MFISS) in mild head injury patients: Cross-Sectional StudyIntroduction: Patients with maxillofacial trauma are at risk of experiencing head injury because of their proximity to the cranium. Plasma D-dimer is the end product of blood clot breakdown that can be measured through blood samples, and it plays a role as a prognostic factor in head injury. The Maxillofacial Injury Severity Score (MFISS) is the latest scoring system to assess the severity of maxillofacial trauma based on the three highest injury scores. Maxillofacial trauma is often accompanied by head injury with increased D-dimer levels. This study aims to analyze the relationship between plasma D-dimer levels and the severity of maxillofacial trauma based on MFISS, serving as a prognostic consideration. Methods: The present study employed a quantitative cross-sectional design. The study was conducted on 38 subjects aged over 18 years with maxillofacial trauma accompanied by mild head injury in the 2-24 hour phase at the Emergency Department of Hasan Sadikin Hospital, Bandung. The severity of maxillofacial trauma was assessed using MFISS, and mild head injury was assessed based on the Glasgow Coma Scale (GCS). Blood samples were taken for plasma D-dimer examination. Data were analyzed using the Spearman Rank correlation test. Results: The mean plasma D-dimer level was 3.42 pg/dL (p=0.001), and the mean MFISS score was 6.89 ± 1.91 (p=0.022). There was a moderate positive correlation between D-dimer levels and MFISS scores (r=0.512). Conclusion: Plasma D-dimer levels are elevated in maxillofacial trauma accompanied by mild head injury. A significant relationship was found between D-dimer levels and the severity of maxillofacial trauma based on MFISS.
Korelasi kadar vascular endothelial growth factor (vegf) saliva dengan gambaran klinis jaringan parut pada pasien pasca operasi labioplasti: studi analitik korelational Laksmitarani, Niken; Hardianto, Andri; Hadikrishna, Indra
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 36, No 3 (2024): Desember 2024
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v36i3.57695

Abstract

Pendahuluan: Jaringan parut pada labioplasti adalah hasil yang tak dapat dihindarkan dari luka operasi. Jaringan parut ini dapat menimbulkan masalah secara fungsional, kosmetik dan psikologis. Penilaian objektif memberikan pengukuran kuantitatif pada jaringan parut, sedangkan penilaian subjektif bergantung pada penilaian pengamat. Skala yang digunakan untuk mengevaluasi berbagai tipe jaringan parut salah satunya Vancouver Scar Scale (VSS). Penilaian objektif yang digunakan pada penelitian ini adalah nilai Vascular Endothelial Growth Factor (VEGF) diketahui sebagai mediator angiogenesis yang mempromosi penyembuhan luka kutan dan merangsang pembentukan jaringan parut. Tujuan penelitian ini adalah untuk menganalisis korelasi kadar vascular endothelial growth factor saliva dengan gambaran klinis jaringan parut pada pasien pasca operasi. Metode: Penelitian ini merupakan penelitian korelasi analitik dengan desain cross sectional yang menilai korelasi antara korelasi antara kadar VEGF dengan gambaran klinis jaringan parut pada 36 pasien dengan kasus celah bibir unilateral yang telah dilakukan operasi labioplasti di Rumah Sakit Gigi dan Mulut Pendidikan Fakultas Kedokteran Gigi Universitas Padjadjaran. Subjek pada penelitian ini adalah pasien yang memenuhi kriteria inklusi. Pemilihan subjek penelitian untuk kelompok uji dilakukan secara nonprobability sampling. Setelah dilakukan tindakan labioplasti, dilakukan pengukuran kadar VEGF pada hari ke-21, selanjutnya dilakukan penilaian gambaran klinis jaringan parut dengan VSS pada hari ke-90. Data yang terkumpul dianalisis dengan menggunakan uji korelasi Rank Spearman. Hasil: Terdapat korelasi yang kuat dan bermakna secara statistik antara kadar VEGF dengan gambaran klinis jaringan parut. Nilai koefisien korelasi antara VEGF dan gambaran klinis jaringan parut sebesar r=0,804 (p=0.001), yang dapat diartikan sebagai korelasi positif. Simpulan: Terdapat korelasi antara nilai VEGF saliva dengan gambaran klinis jaringan parut pada pasien pasca operasi labioplasti.Correlation between vascular endothelial growth factor (vegf) saliva with clinical features of scar tissue in patients post labioplasty surgery: study cross sectionalIntroduction: Scarring in labioplasty is an unavoidable outcome of a surgical wound. Such scarring can cause functional, aesthetic, and psychological complications. Objective assessments provide quantitative measurements of scarring, whereas subjective assessments rely on observer judgement. The scale used to evaluate various types of scarring is the Vancouver Scar Scale (VSS). The objective assessment used in this study is the value of Vascular Endothelial Growth Factor (VEGF), known as a mediator of angiogenesis that promotes cutaneous wound healing and stimulates scar tissue formation. Methods: This study is an analytical correlation study with cross-sectional design that assesses the relationship between VEGF levels and the clinical picture of scarring in 36 patients with unilateral cleft lip who had undergone labioplasty surgery at the Faculty of Dentistry Teaching Dental and Oral Hospital, Padjadjaran University. The subjects in this study were patients who met the inclusion criteria. The selection of research subjects for the test group was carried out by non-probability sampling. VEGF levels were measured on the 21st postoperative day, and the clinical picture of scar tissue was assessed using the VSS on the 90th postoperative day. The collected data were analyzed using the Spearman rank correlation test. Results: The findings demonstrated a strong and statistically significant positive correlation between salivary VEGF levels and the clinical picture of scarring. The correlation coefficient between VEGF and the clinical picture of scarring was r=0.804 (p=0.001), indicating a significant association. Conclusion: There is a significant positive correlation between salivary VEGF levels and the clinical picture of scarring in patients after labioplasty surgery.
Correlation of the modified dental anxiety scale value with salivary alpha-amylase in pre-odontectomy patients Wulansari, Daisy; Hadikrishna, Indra; Syamsudin, Endang
Padjadjaran Journal of Dentistry Vol 32, No 2 (2020): July 2020
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no2.15304

Abstract

Introduction: Odontectomy is a minor surgical procedure that often results in dental anxiety. Dental anxiety can interfere during odontectomy treatment. Dental anxiety can be examined using the Modified Dental Anxiety Scale (MDAS) and through the level of the salivary alpha-amylase enzyme, both of which are dental anxiety biomarkers. The objective of this study was to analyse the correlation between anxiety values with salivary alpha-amylase levels using MDAS as an indicator of anxiety in pre-odontectomy patients. Methods: This study was conducted on 60 research samples of women aged 18-40 years who came to the minor surgery clinic of Department of Oral and Maxillofacial Surgery, Universitas Padjadjaran Dental Hospital, to have odontectomy treatment of maxillary or mandibular third molars impaction, not having systemic and oral diseases, and willing to participate in this study. Patients who met the inclusion criteria then required to sign the research consent statement; afterwards, the MDAS data was taken. The salivary alpha-amylase enzyme data was taken using the Cocoro meter (Nipro, Japan) tip which was kept under the tongue for 30 seconds, then the tip was inserted into the monitor, and the enzyme levels would be counted. The data obtained will be analysed using the Spearman rank correlation test. Results: The results showed that there was a significant relationship (p < 0.01) with a strong positive correlation (r = 0.85). Conclusion: There is a correlation between MDAS value and salivary alpha-amylase enzyme as an indicator of dental anxiety.
The Role of p53 Gene In Molecular Pathogenesis of Oral Squamous Cell Carcinoma Nabilla, Firyal; Hadikrishna, Indra; Yusuf, Harmas Yazid
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.9906

Abstract

Introduction: Oral squamous cell carcinoma is the most common malignant tumor in oral and originates from the epithelial tissue. Carcinoma formation is a genetic process that triggers changes in cell morphology and behavior. Abnormalities in cell cycle control, regulated by p53 among these factors. This study was conducted to examine the role of p53 and p53-related proteins in the formation of oral squamous cell carcinoma. Review: p53 is a component of the genome associated with the development of cancer in humans. Several studies have suggested that p53 is an important antitumor weapon. In the cell cycle, p53 is recognized if there is a cell mutation or the presence of an oncogene, and delays the cell cycle to prevent cells from becoming cancerous. The level of p53 will increase and react by arresting the cell cycle, directing cells to repair or undergo apoptosis. If p53 does not function, the cell cycle carrying damaged genetic material continues and is unable to undergo apoptosis. As a result, cells continue to proliferate with genetic abnormalities that can lead to malignancy. Conclusion: Loss of p53 function can cause random mutations, chromosomal changes, and aneuploidy, which drive the growth of cancer cells to a malignant state. Analysis of changes at the molecular level can be a major diagnostic tool to guide treatment and identify changes associated with oral squamous cell carcinoma.
Impacted Lower Third Molar Profile at Dental Hospital of Padjadjaran University Akbar, Muhammad Fauzi; Hadikrishna, Indra; Riawan, Lucky; Lita, Yurika Ambar
Journal of Indonesian Dental Association Vol 5 No 2 (2022): October
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v5i2.902

Abstract

Introduction: Impacted teeth are teeth that erupt incompletely in the normal eruption period. This situation can be caused by hard or soft tissue obstructions or a lack of arch jaw. Objectives: This study aimed to determine the impacted lower third molar teeth profile by age, sex, class, angulation, treatment, and anesthesia at RSGM UNPAD in 2017-2019. Methods: The study was conducted from February 8, 2020, to March 8, 2020. The study represents the impacted lower third molar teeth profile of patients referred to Outpatient Installation, Central Surgical Installation, and the Radiology Installation. Classification of tooth impaction was based on Pell & Gregory and Winter classifications using ImageJ application, while Intraclass Correlation Coefficient (ICC) was used to confirm data validity. Results: There were 146 impacted dental cases, with a total case of 62 (42.5%) for males and 84 (57.5%) for females. Most impacted teeth occurred in the 12-25 years age group up to 72 (49.3%). A total of 177 impacted teeth mostly occurred in 48 teeth, as many as 91 (51.4%). Impaction class Pell & Gregory class B with 110 (62.1%) cases were found the most. Based on the anterior border of ramus, class II with 164 (91.1%) cases was found the most. Horizontal (79 cases, 44.6%) became the most frequent angulation. The procedures taken were all odontectomy 177 (100%) with more use of local anesthesia 136 (93.2%) compared to general anesthesia 10 (6.8%). Conclusion: Cases of impacted lower third molar teeth at RSGM UNPAD in 2017-2019, were most common in females and mostly in the 12-25 years age group, with Pell & Gregory class IIB classification and Winter horizontal angulation classification, all procedures performed were odontectomy, majority using local anesthesia.
Etiology and Pathogenesis of Unicystic Ameloblastoma Based on The Histopathology Examination Result Analysis Harianto, Azzah Aqillah; Hardianto, Andri; Hadikrishna, Indra
Journal of Indonesian Dental Association Vol 7 No 1 (2024)
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v7i1.1022

Abstract

Unicystic ameloblastoma is a type of ameloblastoma that often occurs at a young age. Unicystic ameloblastoma can occur due to neoplastic transformation from an odontogenic cyst to an odontogenic tumor, ameloblastic transformation of reduced enamel epithelium from developing teeth, or cystic degeneration of solid ameloblastoma. However, there is no convincing evidence has yet been found for each proposed pathogenesis. This study aims to determine the development of etiology and pathogenesis of unicystic ameloblastoma based on the analysis of the results of histopathological examination. This study aims to determine the development of etiology and pathogenesis of unicystic ameloblastoma based on the analysis of the results of histopathological examination. The study was conducted using a systematic review method through searching journals on PubMed, Google Scholar and Scopus using keywords. In the initial search, 1109 journals were obtained, which were then selected based on inclusion criteria, namely English-language journals published in 2017-2020, indexed in Scopus, and relating to the etiology and pathogenesis of unicystic ameloblastoma based on the analysis of the results of histopathological examination, so that 16 journals were obtained. Etiology of the unicystic ameloblastoma has not undergone renewal, and the currently known pathogenesis of the unicystic ameloblastoma is molecular pathogenesis, namely where the development of odontogenic lesions occurs due to pathogenic gene mutations that affect the signaling pathway. The mutation that often occurs is the BRAF V600E mutation which is included in the MAPK signaling pathway.
Co-Authors Abel Tasman Yuza Abel Tasman Yuza, Abel Tasman Akbar, Muhammad Fauzi Alifya Fahira Andri Hardianto Aulia Hanafitri Bambang Hudiworo Bambang Hudiworo K.D Basaria Manurung Cynthia Deianira Dewi Eka Marwansyah Oli’I Endang Sjamsudin Endang Sjamsudin Endang Syamsudin Endang Syamsudin Endang Syamsudin Fadli Ashar Fajar Rezandaru Farah Asnely Putri Ginda Adilla Suwandi Hadiputri, Felicia Harianto, Azzah Aqillah Harmas Yazid Yusuf Hudiworo K.D, Bambang Ivan Surya Pradipta Jihad Harun Sandiah Kirana Lina Gunawan Laksmitarani, Niken Lucky Riawan Lucky Riawan Lusi Epsilawati Marwansyah Oli’I, Eka Melita Sylvyana, Melita Merry Annisa Monica Siregar Nabilla, Firyal Nurul Darmawulan Pebrian Diki Prestya, Pebrian Diki Prihatni, Delita Putri, Jihan Nahdatul Qurrataayuni, Rahimahullah Kamilatinnisa Rizki, Kiki Achmad Saleh, Ardian Salsabila, Anisah Rifda Sarasti Laksmi Anindita Septiani, Tiara Ika Seto Adiantoro Seto Adiantoro, Seto Sri Tjahajawati, Sri Suhardjo Sitam Vetnizah Juniantito Wulansari, Daisy Yurika Ambar Lita Yurika Lita Zahrah Diva Shasya