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All Journal Sosiohumaniora Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Cosmogov: Jurnal Ilmu Pemerintahan Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Journal of Dentomaxillofacial Science Padjadjaran Journal of Dental Researchers and Students Jurnal Material Kedokteran Gigi Jurnal Kesehatan Gigi dan Mulut (JKGM) Journal of Health and Dental Sciences Makara Journal of Science eProceedings of Engineering
Nina Djustiana
Bagian Ilmu Dan Teknologi Material Kedokteran Gigi Fakultas Kedokteran Gigi Universitas Padjadjaran Bandung, Indonesia
Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Tissue reaction against implantation of nanocomposite and giomers Vilvarajah, Anusha S; Djustiana, Nina; Widyaputra, S. Sunardhi
Padjadjaran Journal of Dentistry Vol 23, No 1 (2011): March
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3007.105 KB) | DOI: 10.24198/pjd.vol23no1.14057

Abstract

Dentistry today has inherited technological advancement from other Dental Material sciences, examples are Nanocomposite and Giomers. Nanocomposites and Giomers are common materials used in Dentistry. But what are the implications when these materials are used in practice? The aim for this the study shows the analysis of tissue reaction due to implantation of Nanocomposite and Giomers. The subcutaneous tissue of a mouse is substituted with the human gum tissues. In the experimental group, Nanocomposite and Giomers were implanted in the subcutaneous tissue abdomen region in mice. The slides were made from the surrounding of implantation for both experimental and control groups. The evaluation of the effects of the implant is done in a time interval. Evaluated time intervals are 24 hours, 7" day, 14th day, 21st day and 28th day respectively. The amounts of inflammatory cells formation in both groups were compared.Once the results of the inflammatory cells are evaluated in the given time interval for Nanocomposite, Giomer, and control group then they are statistically analyzed. The statistics used in the experiments is Mann-Whitney and Wilcoxon. The conclusion of this research showed that statistically significant differences on lymphocytes value between treatment and control group.
UPAYA PENANGANAN KORBAN DAN PENCEGAHAN TINDAK PERDAGANGAN ORANG (HUMAN TRAFFICKING) DI KABUPATEN INDRAMAYU PROVINSI JAWA BARAT Bintari, Antik; Djustiana, Nina
CosmoGov Vol 1, No 1 (2015)
Publisher : Departemen Ilmu Pemerintahan FISIP UNPAD

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.194 KB) | DOI: 10.24198/cosmogov.v1i1.11803

Abstract

Kejahatan perdagangan orang (human trafficking) adalah kejahatan kemanusiaan yang terorganisasi, artinya kejahatan ini melibatkan beberapa orang yang memiliki jaringan atau keterkaitan satu sama lain dan memiliki tujuan untuk mengeksploitasi korban demi keuntungan sepihak (pelaku). Dalam kurun waktu 2005-2009, Jawa Barat menduduki peringkat teratas kasus human trafficking. Salah satu daerah di Provinsi Jawa Barat yang merupakan daerah rentan menghadapi permasalahan tindak  human trafficking adalah Kabupaten Indramayu. Berbagai data menyebutkan bahwa kasus human trafiking di Kabupaten Indramayu selalu mengalami peningkatan setiap tahunnya. Penelitian kali ini mencoba menghadirkan hal-hal yang telah dan akan dilakukan oleh stakeholder di Kabupaten Indramayu dalam meminimalisasi tingkat tindak human trafficking
Description of palatal rugae size and direction in children with gender difference Nur, Muhammad Arfianto; Djustiana, Nina; Malinda, Yuti
Padjadjaran Journal of Dentistry Vol 30, No 1 (2018): March
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (160.194 KB) | DOI: 10.24198/pjd.vol30no1.14323

Abstract

Introduction: Indonesia has a high number of children victims of disaster in the last five years, but the children do not have identity cards, causing difficulties in the identification process. Palatal rugae are considered unique in individuals, and their morphology remains stable throughout life. Data of palatal rugae pattern in children aimed to facilitate the process of identification of the childs gender. The purpose of this research was to discover the description of palatal rugae in children which can be used as a reference of gender identification in children. Method: A descriptive research design was performed with purposive sampling method. Samples were taken from 119 maxilla images consisted of 69 images of girls maxilla and 50 images of boys maxilla. The study was performed by taking individual maxilla images with intraoral mirror and observing towards the direction of the palatal rugae according to the Carrea classification, and the size of palatal rugae according the Lysell classification. Results: The type IV direction and secondary size of palatal rugae were found to be dominant on both sides of maxilla in boys and girls. Conclusion: Palatal rugae in boys and girls were having the same direction which was the type IV, and the size of secondary rugae was found to be dominant on both sides of the palate. Palatal rugae also proofed to be able to become the complementary method for determining unidentified gender in children.
The comparison of surface hardness between thermoplastic nylon resin and heat-cured acrylic resin Utami, Marina; Febrida, Renny; Djustiana, Nina
Padjadjaran Journal of Dentistry Vol 21, No 3 (2009): November
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.61 KB) | DOI: 10.24198/pjd.vol21no3.14117

Abstract

The surface hardness level of a denture base material is related to the resistance to abrasion, scratch, polishing and water sorption. Nowadays, thermoplastic nylon resins and heat-cured acrylic resins are used as denture base materials. Denture base must be immersed in water to maintain its humidity. The objective of this research was to compare the surface hardness level between thermoplastic nylon resins and heat-cured acrylic resins. Materials used for the research were thermoplastic nylon resins from Valplast and heat-cured acrylic resins QC-20, with a sample size of 64x(10±0.03)x(2.5±0.03) mm. Surface hardness is measured with Vickers Microhardness Tester and the data were analyzed by ANOVA method. The results showed that comparison ratio of surface hardness level between thermoplastic nylon resins and heat-cured acrylic resins before immersion is 3.2:7.3 VHN respectively, while the comparison value of both resins after immersion is 2.8:6.6 VHN. In conclusion, the surface hardness level of thermoplastic nylon resins is lower compared to heat-cured acrylic resins. This result is due to thermoplastic nylon resin’s higher porosity, its different polymer chains, and the plasticizers effect after immersion in water.
Hardness evaluation of dental composites fabricated from the uniform size and well-distributed zirconia-alumina-silica fillers with sol-gel technique Hakim, Muhammad Lukman Nur; Hasratiningsih, Zulia; Djustiana, Nina; Sunendar, Bambang; Faza, Yanwar
Padjadjaran Journal of Dentistry Vol 30, No 2 (2018): July
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.347 KB) | DOI: 10.24198/pjd.vol30no2.18319

Abstract

Introduction: Several factor limits of services of dental composite have triggered further improvement. ZrO2-Al2O3-SiO2 system as filler of dental composite had been developed with sol-gel technique. Ultrasonic homogeniser were reported to change the particle size ditribution or shape. Unifom size and distribution of particle is believed to help define the behavior of hardness properties. Methods: The study was an laboratory experimental design. Filler ZrO2-Al2O3-SiO2 system were developed via sol-gel methods. Post calcination process, filler were immerse in ethanol and applied with ultrasonic homogeniser, with various amplitude i.e 50 rpm, 60 rpm and 80 rpm then named sample A, B, and C. XRD, SEM anda PSA were used to characterize of filler system. Subsequent filler were used to fabricate dental composite then evaluate the hardness value using micro-hardness tester. One–way ANOVA was used to analysis the statistical result of hardness value. Results: XRD pattern of three sample were similar in which tetragonal zirconia was prominent (57-61 %) followed by monoclinic zirconia (24-25%) and amorphous (15-17 %). While, SEM and PSA characterization showed amplitude 50 rpm (sample A) produce more uniform size and well-distributed particle filler than the others. In contrary, sample B and C showed higher peak in PSA results. It means there was dominating of filler with particular size.  However, the hardness value did not show significant differences between those filler (p>0,05). Conclusion: Dental composite that contain of different uniformity and distribution of filler ZrO2-Al2O3-SiO2 system has no significantly differences of hardness value.
Sintesis partikel zirkonia-alumina-silika (ZrO2-Al2O3-SiO2) dari pasir zirkon alam sebagai bahan pengisi komposit kedokteran gigiSynthesis of zirconia-alumina-silica particles (ZrO2-Al2O3-SiO2) from natural zircon sand as dental composite fillers Febrida, Renny; Joni, I Made; Susra, Silmina; Djustiana, Nina
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 29, No 1 (2017): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.075 KB) | DOI: 10.24198/jkg.v30i2.18537

Abstract

Pendahuluan: Pasir zirkon (ZrSiO4) merupakan mineral alam yang tersusun atas zirkonia (ZrO2) dan silika (SiO2) yang berikatan dengan stabil. Zirkonia adalah salah satu material keramik kedokteran gigi yang banyak digunakan karena memiliki sifat mekanis dan biokompatibilitas yang tinggi. Zirkonia dapat dikombinasikan dengan silika dan alumina untuk membentuk suatu bahan pengisi komposit dengan sifat mekanis dan estetis yang dapat disesuaikan dengan sifat gigi kodrat. Tujuan dari penelitian ini adalah untuk menghasilkan bahan bahan pengisi komposit alternatif di bidang kedokteran gigi yang berasal dari pasir zirkon alam untuk dijadikan bahan bahan pengisi komposit. Metode: Jenis penelitian yang dilakukan adalah eksperimental laboratoris untuk mensintesis dan mengkarakterisasi partikel ZrO2-Al2O3-SiO2 dari bahan baku alam berupa pasir zircon dengan reaksi geopolimerisasi dan proses pemanasan suhu tinggi. Aktivator yang digunakan adalah larutan NaOH 3 mol dengan temperatur pemanasan 1100° C pada lama pemanasan 4 jam, 6 jam, dan 8 jam.  Hasil: Hasil analisis uji X-Ray Diffraction (XRD) menunjukkan jumlah zirkonia berstruktur tetragonal terbesar ada pada sampel pemanasan 8 jam, yaitu 24%. Hasil analisis uji Energy Dispersive Spectroscopy (EDS) menunjukkan rasio komposisi zirkonia-alumina-silika dengan nilai zirkonia tertinggi ada pada sampel pemanasan 8 jam, yaitu 55,7 : 23,6 : 20,6. Hasil analisis mikrograf Scanning Electron Microscope (SEM) menunjukkan morfologi permukaan dan partikel yang tidak beraturan dan beraglomerasi. Simpulan: Sintesis partikel zirkonia-alumina-silika (ZrO2-Al2O3-SiO2) dari pasir zirkon alam dengan pemanasan 8 jam ditinjau dari jumlah zirkonia berstruktur tetragonal memadai digunakan sebagai bahan pengisi komposit berdasarkan uji XRD danEDS, namun pada ujiSEM partikel berbentuk tidak beraturan dan beraglomerasi. ABSTRACTIntroduction: Zircon sand (ZrSiO4) is a natural mineral that is composed of zirconia (ZrO2) and silica (SiO2) which binds stable. Zirconia is a dental dentistry material that is widely used because it has high mechanical properties and biocompatibility. Zirconia can be combined with silica and alumina to form a composite filler with mechanical and aesthetic properties that can be adapted to the nature of natural teeth. The purpose of this study was to produce alternative composite fillers in the field of dentistry derived from natural zircon sand to be used as composite fillers. Methods: This type of research was experimental laboratory to synthesize and characterize ZrO2-Al2O3-SiO2 particles from natural raw materials in the form of zircon sand with geopolymerization reaction and high temperature heating process. The activator used is a 3 mol NaOH solution with a heating temperature of 1100 ° C at a heating time of 4 hours, 6 hours, and 8 hours. Results: The results of the X-Ray Diffraction (XRD) test showed that the largest number of zirconia with a tetragonal structure was on an 8-hour heating sample, which was 24%. The results of the Energy Dispersive Spectroscopy (EDS) test analysis show the highest ratio of zirconia-alumina-silica composition with zirconia values in the 8 hour heating sample, which is 55.7: 23.6: 20.6. The results of the Scanning Electron Microscope (SEM) micrograph analysis showed that the surface morphology and particles were irregular and agglomerated. Conclusion: Synthesis of zirconia-alumina-silica particles (ZrO2-Al2O3-SiO2) from natural zircon sand with 8 hours heating in terms of sufficient tetragonal zirconia amount used as composite filler based on XRD and EDS test, but in SEM test irregularly shaped particles and agglomerated.Keywords: Zircon sand, zirconia-alumina-silica, geopolymerisation, composite filler materials
Uji nilai kekuatan tarik serat pelepah pisang (Musa paradisiaca) sebagai bahan alternatif benang gigi biodegradable Alex Kesuma; Nina Djustiana; Yanwar Faza; Renny Febrida; Elin Karlina
Padjadjaran Journal of Dental Researchers and Students Vol 1, No 2 (2017): Oktober 2017
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v1i1.22126

Abstract

Pendahuluan: Benang gigi dari bahan sutera dipilih karena bersifat ramah lingkungan dan biodegradable namun pemanfaatanya mendapat pertentangan dari para ahli perlindugan hewan. Penelitian ini bertujuan untuk menghasilkan benang gigi dari bahan serat pisang kepok (Musa paradisiaca) yang diketahui bersifat biodegradable, memiliki kekuatan tarik yang cukup tinggi dan jumlahnya yang banyak di Indonesia. Metode: Jenis peneltiian berupa eksperimental laboratoris. Prosedur peneltiian dimulai dengan ekstraksi pelepah pisang dengan metode manual kemudian dilanjutkan dengan pengelompokan hasil serat berdasarkan jumlah helai serat. Satu kelompok benang gigi sutera (Radius® Organic Silk Floss) dan hasil serat pisang yang telah di kelompokkan sebanyak tiga kelompok (10,15 dan 20 helai) secara berurutan disebut kelompok 1 (kontrol), 2, 3 dan 4. Semua kelompok dilakukan uji kekuatan tarik menggunakan Materials Testing Machine dan data hasil di analisis menggunakan uji statistik One-way Anova Hasil: Hasil kekuatan tarik menunjukkan kelompok 1, 2, 3 dan 4 menghasilkan nilai uji kekuatan tarik secara berurutan sebagai berikut 130.73 MPa, 141.56 MPa, 391.37 MPa dan 307.06 MPa. Hasil statistik memperlihatkan terdapat perbedaan yang signifikan (p < 0,05) antara kelompok 1 dengan kelompok 3 dan 4, kelompok 2 dengan kelompok 3 dan 4 serta antara kelompok 3 dan 4. Sementara itu, tidak terdapat perbedaan yang signifikan antara kelompok 1 dan 2 (p > 0,05). Simpulan: Hasil kekuatan tarik menunjukkan kelompok 3 memiliki nilai kekuatan tarik tertinggi diantara semua kelompok. Nilai kekuatan tarik serat pisang kelompok 2, 3 dan 4 lebih tinggi dari kontrol sehingga memperlihatkan serat pisang berpotensi sebagai alternatif benang gigi biodegradable.Kata kunci: Benang gigi, biodegradable, kekuatan tarik
Uji sitotoksisitas mikrofiber PMMA dan PMMA-silika wetspinning pada kultur sel primer L-929 sebagai aplikasi penguat jembatan gigi direkCytotoxicity test of PMMA and PMMA-silica wet spinning microfibers in L-929 primary cell culture as a direct dental bridge reinforcement application Nina Djustiana; Yanwar Faza; Andri Hardiansyah
Padjadjaran Journal of Dental Researchers and Students Vol 5, No 2 (2021): Oktober 2021
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v5i2.36304

Abstract

ABSTRAK Pendahuluan: Jembatan gigi direk terdiri dari komponen penguat fiber dan komponen matriks resin komposit. Penggunaan sel target untuk uji sitotoksisitas dari material fiber kedokteran gigi umum dilakukan secara ekperimental uji in vitro untuk mengetahui relevansi klinis dari pengujian. Penelitian ini  bertujuan untuk melihat sitotoksisitas dari mikrofiber PMMA dan PMMA-silika wetspinning dengan parameter yang berbeda terhadap kultur sel primer (cell line) fibroblas L-929. Metode: Desain penelitian berupa deksriptif kualitatif.  Sel primer fibroblas L-929 diberi paparan mikrofiber PMMA dan PMMA-silika selama 1, 4 dan 7 hari. Uji sitotoksisitas dilakukan dengan menggunakan uji MTT Assay. Parameter dari mikrofiber PMMA dan PMMA-silika yang digunakan adalah konsentrasi dan laju alir, kemudian dibagi menjadi beberapa kelompok penelitian serta diberi nama sebagai berikut: PMMA mikrofiber sistem vertikal 250ml/jam dengan konsentrasi dalam % 0,75(A); 1(B); 1,25(C); PMMA-silika mikrofiber sistem vertikal dengan kecepatan 200 ml/jam (D), 250 ml/jam (E), 300 ml/jam (F) dan PMMA mikrofiber dengan sistem rotasi 200 ml/jam dengan konsentrasi  dalam % 0,75(G);1(H), 1,25(I); PMMA-silika mikrofiber sistem rotasi dengan konsentrasi 200ml/jam(J), 250ml/jam (K), dan 300 ml/jam (L).  Hasil: Uji in vitro dari gambaran sel L-929 memperlihatkan tidak terdapat Sel primer fibroblas yang mengalami kematian. Kurva pertumbuhan cell line dari setiap parameter mikrofiber memperlihatkan sel dapat berproliferasi selama masa inkubasi dan memperlihatkan kecenderungan positif dari pertumbuhan sel. Simpulan: Mikrofiber PMMA dan PMMA-silika wetspinning tidak memperlihatkan sifat toksisitas terhadap pertumbuhan cell line fibroblas L-929 sehingga mempunyai potensi sebagai aplikasi penguat jembatan gigi direk.  Kata kunci: sitotoksisitas; sel primer fibroblas; fiber; PMMA; PMMA-silika ABSTRACTIntroduction: Direct dental bridge consists of a fiber reinforcement component and a composite resin matrix component. The use of target cells for the cytotoxicity test of dental fiber materials is generally performed by experimental in-vitro tests to determine the clinical relevance of the test. This study was aimed to examine the cytotoxicity of PMMA and PMMA-silica wet spinning microfibers with different parameters on the primary cell culture (cell line) of L-929 fibroblasts. Methods: The research design was descriptive qualitative. Primary L-929 fibroblast cells were consecutively exposed to PMMA and PMMA-silica microfibers for 1, 4, and 7 days. Cytotoxicity test was performed using the MTT Assay. Parameters of PMMA and PMMA-silica microfibers used were concentration and flow rate, then divided into several research groups and named as follows: PMMA microfiber vertical system 250ml/hour with a concentration in %: 0.75(A); 1(B); 1.25(C); PMMA-silica microfiber vertical system with the speed of 200 ml/hour (D), 250 ml/hour (E), 300 ml/hour (F) and PMMA microfiber with rotation system 200 ml/hour with a concentration in % 0.75(G );1(H), 1,25(I); PMMA-silica microfiber rotation system with concentrations of 200ml/hour (J), 250ml/hour (K), and 300 ml/hour (L). Results: In-vitro test of the L-929 cell picture showed no primary fibroblast cells that died. The cell line growth curve of each microfiber parameter shows that the cells can proliferate during the incubation period and show a positive trend of cell growth. Conclusions: PMMA and MMA-silica wet spinning microfibers did not show any toxicity to the growth of the L-929 fibroblast cell line, so they have potential as reinforcement applications for direct dental bridges.  Keywords: cytotoxicity; fibroblast primary cells; fiber; PMMA; PMMA-silica
Nilai pH hidrolisis pada teknik sol-gel terhadap ukuran dan zeta potensial partikel keramik mullite sebagai bahan pengisi komposit kedokteran gigi Yanwar Faza; Nina Djustiana; Arief Cahyanto; I Made Joni; Kosterman Usri
Padjadjaran Journal of Dental Researchers and Students Vol 1, No 2 (2017): Oktober 2017
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v1i1.22298

Abstract

Pendahuluan: Kecenderungan aggregasi dan aglomerasi partikel keramik ukuran nano di dalam resin (komposit kedokteran gigi) menjadi suatu tantangan untuk dapat mensintesis nano partikel mullite dengan teknik solution gelation (sol-gel). Nilai pH hidrolisis pada teknik sol-gel diketahui mempengaruhi ukuran dan zeta potensial partikel keramik sehingga mempengaruhi kestabilan distribusi partikel keramik di dalam cairan. Metode: Desain penelitian berupa penelitian deskriptif. Partikel mullite dihasilkan melalui prekursor tetraethyl orthosilicate (TeOS) dan aluminium nitrate (Al2(NO3)3) yang di dicampurkan pada tahap hidrolisis dengan pengaturan pH yang bervariasi: pH 2, pH 3 dan pH 4. Partikel mullite yang dihasilkan di karakterisasi menggunakan Dynamic light scattering (DLS) untuk mengetahui ukuran dan zeta potensial partikel mullite. Hasil: Ukuran rerata partikel mullite yang dihasilkan pada pH 2, 3 dan 4 berturut-turut adalah 2349,7 nm, 1281 nm dan 245,9 nm. Hasil memperlihatkan penurunan ukuran partikel seiring dengan peningkatan pH. Mulite dengan pH hidrolisis 4 berukuran nanometer, sementara mullite dengan pH 2 dan 3 berukuran mikron. Sementara itu, nilai zeta potensial pada keramik mullite yang dihasilkan pada pH 2, 3 dan 4 berturut-turut adalah 31,7 mV, 40,7 mV dan 29,2 mV. Nilai zeta potensial pada semua kelompok mullite, masuk pada kategori stabil. Simpulan: Partikel mullite yang dihasilkan dengan pH hidrolisis 4 dapat menjadi alternatif bahan pengisi kedokteran gigi karena memiliki ukuran nano dan kestabilan partikel yang baik.Kata kunci: Mullite, pH hidrolisis, ukuran partikel, zeta potensial, sol-gel
Perbedaan pelepasan ion nikel kawat ortodonti stainless steel yang direndam dalam obat kumur ekstrak buah mengkudu (Morinda citrifolia L.Differences of the nickel ions release of orthodontic stainless steel wire immersed in various concentrations of noni fruit (Morinda citrifolia L.) extract mouthwash Angeline Angeline; Nina Djustiana; Nazruddin Nazruddin
Padjadjaran Journal of Dental Researchers and Students Vol 5, No 2 (2021): Oktober 2021
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v5i2.33407

Abstract

ABSTRAK Pendahuluan: Pasien dengan perawatan ortodonti rentan mengalami gingivitis dan karies, sehingga dokter gigi tidak jarang meresepkan obat kumur. Namun, obat kumur komersial dapat menyebabkan pelepasan ion nikel (Ni+) pada kawat orthodonti berbahan Stainless steel (SS). Pelepasan ion  nikel (Ni+) dapat berpengaruh pada tubuh manusia dan sifat mekanis logam. Buah mengkudu (Morinda citrifolia L.) diketahui memiliki kandungan tanin yang dapat berperan sebagai coating agent, sehingga dapat mengurangi korosi. Penelitian ini bertujuan menganalisis perbedaan pelepasan ion Ni+ kawat SS yang direndam dalam obat kumur ekstrak buah mengkudu. Metode: Jenis penelitian adalah eksperimental laboratories. 30 kawat direndam dalam lima kelompok. Setiap kelompok berjumlah enam sampel (rumus Federer). Kelompok kontrol yaitu:  kelompok A (kontrol negatif, saliva buatan, pH 6,8) dan kelompok B (kontrol positif, klorheksidin 0,2%). Kelompok perlakuan yaitu: kelompok C (obat kumur mengkudu 2,5%), kelompok D (obat kumur mengkudu 5%) dan kelompok E (obat kumur mengkudu 7,5%). Ekstrak diperoleh secara maserasi dan uji fitokimia dilakukan untuk melihat kandungan tanin. Kawat kemudian direndam dan dimasukan dalam inkubator selama 35 hari. Pelepasan ion dianalisis dengan Atomic Absorption Spectrophotometer (AAS) Hasil: Rerata pelepasan ion setiap harinya selama 35 hari untuk kelompok A sampai E secara berurut adalah 2,185 μg/ hari, 1,185 μg/ hari, 1,202 μg/ hari, 1,322 μg/ hari, dan 1,428 μg/ hari dan masih sesuai dengan rekomendasi WHO yaitu 25-35 μg/ hari. Uji statistik Least Significant Difference (LSD) menunjukkan adanya perbedaan bermakna antar kelompok (p< 0,05), tetapi tidak adanya perbedaan bermakna antara kelompok saliva dengan mengkudu 2,5% p=0,388. Simpulan: Terdapat perbedaan pelepasan ion Ni+ kawat SS ortodonti yang direndam dalam obat kumur ekstrak buah mengkudu  (Morinda Citrifolia L.) dengan konsentrasi berbeda. Obat kumur mengkudu 2,5% merupakan konsentrasi yang paling mendekati kelompok kontrol negatif (saliva buatan). Kata kunci: stainless steel; kawat ortodonti; pelepasan ion nikel; buah mengkudu; Morinda citrifolia L. ABSTRACT Introduction: Orthodontic appliance users are prone to gingivitis and caries; thus, dentists often prescribe mouthwash. However, commercial mouthwash can cause the release of nickel ions (Ni+) in stainless steel (SS) orthodontic wires. The release of nickel ions (Ni+) can affect the human body and the mechanical properties of metals. Noni fruit (Morinda citrifolia L.) contains tannins that can act as a coating agent, reducing corrosion. This study was aimed to analyse the differences in the nickel ions release of orthodontic SS wire immersed in various concentrations of noni fruit (Morinda citrifolia L.) extract mouthwash. Methods: The research was experimental laboratories. Thirty wires were immersed in five groups. Each group consisted of six samples (Federer’s formula). The control groups were: Group A (negative control, artificial saliva, pH 6.8) and Group B (positive control, 0.2% chlorhexidine). The treatment groups were: Group C (2.5% noni mouthwash), group D (5% noni mouthwash) and group E (7.5% noni mouthwash). The extract was obtained with maceration, and the phytochemical test was carried out to observe the tannin content. The wire was then immersed and kept in an incubator for 35 days. Ion release was analysed by the Atomic Absorption Spectrophotometer (AAS). Results: The average daily ion release for 35 days in groups A to E were 2.185 g/day, 1.185 g/day, 1.202 g/day, 1.322 g/day, and 1.428 g/day respectively, which was still following the WHO recommendations, 25-35 g/day. The Least Significant Difference (LSD) statistical test showed a significant difference between groups (p<0.05), however, there was no significant difference between the salivary group of 2.5% noni mouthwash (p=0.388). Conclusions: There are differences in the nickel ion release of orthodontic stainless steel wire immersed in noni fruit mouthwash extract with different concentrations. 2.5% noni mouthwash is the concentration with the closest result with the negative control group (artificial saliva). The higher the concentration, the higher the nickel ion release value. Keywords: stainless steel; orthodontic wire; nickel ion release; noni fruit; Morinda citrifolia L.
Co-Authors Akhyar Dyni Zakyah Alex Kesuma Amida, Aya Andri Hardiansyah Angeline Angeline Antik Bintari Anusha S Vilvarajah, Anusha S Arief Cahyanto Arief Cahyanto Asri, Lia Amelia Tresna Wulan Ayu Trisna Hayati Bambang Hidayat Bambang Sunendar Bambang Sunendar Binahayati Rusyidi Cahyanto, Arief Camellia Panatarani Dudi Aripin Elin Karlina Elin Karlina Elin Karlina Elin Karlina Elin Karlina Fourier Dzar Eljabbar Latief Gema Gempita Hadi, Bambang Kismono Hakim, Muhammad Lukman Nur Hakim, Muhammad Lukman Nur Hardiansyah, Andri I Made Joni I Made Joni Kosterman Usri Mardhian, Deby Fajar Marina Utami, Marina Marry Siti Mariam Muhammad Asrun Adi Saputra Syam Mutia Annisa Nabilla Nazruddin Nazruddin Nik Alyana Syakirin Nur, Muhammad Arfianto Nur, Muhammad Arfianto Rasinia Vadilla Nova Renny Febrida Renny Sekarningsih Rosidah Nurhayati S. Sunardhi Widyaputra, S. Sunardhi Sanjaya, Arya Silmina Susra Sri Tjahajawati Sukotjo, Cortino Sunardhi Widyaputra Susra, Silmina Veni Takarini Viona, Nona Wijaya, Dissa Kirana Yanwar Faza Yanwar Faza Yanwar Faza Yohannes, Gabriel Yuti Malinda Zulia Hasratiningsih Zulia Hasratiningsih Zulia Hasratiningsih Zulia Hasratiningsih Zulia Hasratiningsih, Zulia