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Journal : Scripta Biologica

PENGARUH AIR REBUSAN DAUN MAMPELAS (Teteracera indica) TERHADAP AKTIVITAS MOTORIK MENCIT Zico Fakhrur Rozi
Scripta Biologica Vol 5, No 2 (2018)
Publisher : Fakultas Biologi | Universitas Jenderal Soedirman

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Abstract

Plants (Tetracera indica) commonly used by communities Musi North Rawas District for a variety of treatments. This study aims to see the effect of the use of leaf memelas to motor movement male mice. This research is true experimental with the design of Post-test only with control group design. 25 male mice divided into 5 groups. P0 was given 0 g leaf mampelas, P1 was given 2 g leaf mampelas, P2 was given 5 g leaf mampelas, P3 10 g leaves mampelas and P4 extra joss 10 mg. Treatment activities for 7 days. The calculation of motor motion is done by performing a series of tests with each of 3 repetitions, which consist of negative geotaxis test, swing test and swimming test. From the result of statistical analysis using Kruskal Wallis test, it is known that the boiled leaf water does not affect the negative geotaxis test (0,33>0,05), does not affect the hanging test (0,57>0,05) and swimming endurance  Based on the above data it can be concluded that boiling water does not affect the influence of motor activity of mice.
PENGARUH AIR REBUSAN DAUN MAMPELAS (Tetracera indica Merr.) TERHADAP KADAR KOLESTEROL DARAH MENCIT Dian Samitra; Zico Fakhrur Rozi
Scripta Biologica Vol 4, No 3 (2017)
Publisher : Fakultas Biologi | Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.298 KB) | DOI: 10.20884/1.sb.2017.4.3.453

Abstract

Tetracera indica Merr. locally known as Mampelas is commonly used in traditional remedies. It believed to have the potential to cure hypercholesterolemia. The potential use of this plant to lower blood cholesterol level was understudied; therefore this study aimed to determine the effect of the infusion of fresh leaves of Tetracera indica to the blood cholesterol levels of mice. This research was true experimental design, a post-test only design with nonequivalent (control) groups. This study used 25 male mice divided into five categories, i.e., P0 mice were administered with 0 g of infusion, P1 mice with 2 g infusion, P2 mice with 5 g infusion, P3 mice with 10 g infusion, and P4 mice without Tetracera indica infusion but 10 mg of simvastatin. The treatment in all categories were given continuously for seven days. The results showed the mean of the blood cholesterol levels were 169.4 ± 59.37 mg/dL in P0, 121.8 ± 7.62 mg/dL in P1, 136.2 ± 15.69 mg/dL in P2, 110.6 ± 37 , 01 mg/dL in P3 , and 179,0 ± 35,24 mg/dL in P4. Kruskal Wallis test was calculated to determine the difference of blood cholesterol level among all groups, and it reported p < 0.05. The results of this study showed that infusion of Tetracera indica leaf was significantly lowered the level of blood cholesterol in mice.