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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Wiyata : Penelitian Sains dan Kesehatan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Majalah Farmasetika Jurnal Inovasi Farmasi Indonesia JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Indonesian Journal of Pharmaceutical Education Jurnal Abdi Masyarakat Indonesia Jurnal Farmasi Indonesia Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Kunir: Jurnal Farmasi Indonesia (KJFI)
Esti Ambar Widyaningrum
Fakultas Farmasi Institut Ilmu Kesehatan Bhakti Wiyata
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Factors Affecting Potentially Inappropriate Medications (PIMs) Based on STOPP/START Criteria in Geriatric Patients at RSUD Dr. Soedomo Trenggalek: Faktor-Faktor yang Mempengaruhi Potentially Inappropriate Medications (PIMs) Berdasarkan Kriteria STOPP/START pada Pasien Geriatri di RSUD Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; Fitriani, Marina; Irawati, Reny Nur Satya; Fajriyah, Shofiatul; Kurniawati, Evi; Lestari, Tri Puji
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16641

Abstract

Background: Geriatric patients often have multiple comorbidities and decreased physiological function, leading to polypharmacy and potential exposure to inappropriate medications (PIMs). Objectives: This study investigates geriatric inpatients' characteristic profiles, evaluates PIMs using STOPP/START criteria, and explores factors influencing PIM incidence. Method: This study employed a retrospective observational analytical approach. The sampling technique was purposive sampling. The sample involved in this study was 312 patients. Results: The geriatric patients involved in this study had the following characteristics: 62% male and 38% female; 69% youngest-old (65-74 years), 30% middle-old (75-90 years), and 1% oldest-old (>90 years); 87% with BPJS service type and 13% with general service type; main diagnosis groups of the patients were gastrointestinal of 9%, cardiovascular of 31%, respiratory of 3%, neurological of 1%, infection of 11%, endocrine of 13%, genitourinary of 15%, immune an malignant of 1%, blood of 11%, musculoskeletal of 2%, eyes of 2% and skin of 1%; 13% patients had one disease, 43% had two diseases, 25% had three diseases, and 19% had ≥ four diseases;29% had 15 drugs, 50% had 6-10 drugs, 17% had 11-15 drugs, 3% had 20 drugs, and 1% had ≥ 20 drugs. There were 72 PIMs based on STOPP/START criteria. The results of the analysis using the C contingency coefficient test showed the following factors, such as gender (p-value of 0.894), age (p-value of 0.470), type of service (p-value of 0.166), main diagnosis (p-value of 0.042), number of illness (p-value of 0.106), and number of drugs (p-value of 0.182). Conclusion: There is a correlation between the main diagnosis factor and PIMs with a p-value of 0.042 (p-value < 0.05).
Analisis Pengaruh Kualitas Layanan Informasi Swamedikasi Online Berbasis Whatsapp Bot Terhadap Kepuasan Masyarakat Widyaningrum, Esti Ambar; Yestari, Farah Eka Julia; Sari, Erni Anika; Srihartini, Indah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1158.686 KB) | DOI: 10.35617/jfionline.v14i2.73

Abstract

Abstract: The innovation of online self-medication information services, one of which is based on WhatsApp Bot, is needed to make it easier for people to find self-medication information for the community. This innovation needs to be continuously developed so that it can provide adequate information services, can increase knowledge and provide satisfaction to users. The purpose of this study was to determine the level of community satisfaction with online self-medication services based on WhatsApp Bot and the effect of expectations on satisfaction using the RATER dimension (Reliability, Assurance, Tangible, Empathy, Responsiveness) in the community of Talun Village, Blitar Regency. The method used in this study is an analytical survey using a cross sectional design. Sampling was done by purposive sampling technique and obtained 264 respondents from the residents of Talun Village, Blitar Regency. Gap analysis was obtained at -0.10 with a level of satisfaction that was not satisfied with the services that had been provided with detailed attributes including: layout, absence of constraints, valid and reliable information, complete information, attention to user needs and the speed of customer service responding, needs to be improved to increase user satisfaction. Spearman rank correlation test obtained P value 0.05 and correlation coefficient value of 0.644. The community is not satisfied with this information service and there is an influence between the quality of information source services and satisfaction in the community of Talun Village, Blitar Regency with a positive correlation and strong correlation strength so it is necessary to develop this Whatsapp Bot-based self- medication information service.
INPATIENT ANTITHROMBOTIC THERAPY FOR MYOCARDIAL INFARCTION : RETROSPECTIVE STUDY Fajriyah, Shofiatul; Nur Rohmah, Dilla Salwa; Astuti, Lelly Winduhani; Rilawati, Fentyana Dwi; Wulan, Fitria Wahyuning; Widyaningrum, Esti Ambar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.762

Abstract

Myocardial infarction (MI), a subtype of coronary heart disease (CHD), is still a major cause of morbidity and mortality around the world. Non-ST-segment elevation MI (NSTEMI) is more common than ST-segment elevation MI (STEMI). Antithrombotic therapy, including antiplatelet and anticoagulant agents, is essential in MI management to prevent thrombus formation and reduce ischemic complications. Although international and national clinical guidelines (PERKI and ACC/AHA) provide recommendations tailored to MI type and patient factors, discrepancies in clinical practice, especially in developing countries, may impact treatment outcomes. This retrospective descriptive study aimed to evaluate the use and appropriateness of antithrombotic therapy in NSTEMI and STEMI patients at Hospital X, Kediri City, in 2018. Data were collected from medical records of hospitalized acute myocardial infarction (AMI) patients. Aspirin combined with clopidogrel was the most commonly used regimen for NSTEMI, whereas STEMI patients frequently received aspirin, clopidogrel, and enoxaparin; fibrinolytics were administered in nine STEMI cases. Dosage evaluation showed compliance with guidelines in NSTEMI patients, while 36.84% of STEMI patients, particularly those receiving enoxaparin, were given incorrect dosages. These findings highlight the need for improved adherence to clinical guidelines to optimize antithrombotic therapy outcomes in MI management
Correlation Between the Number of Drugs Prescribed and Potentially Inappropriate Medication (PIMS) Based on Beers Criteria in Geriatric Hypertension Outpatients at Dr. Soedomo Hospital in Trenggalek: Hubungan Jumlah Obat terhadap Potentially Inappropriate Medication (PIMS) Berdasarkan Beers Criteria pada Pasien Hipertensi Geriatri Rawat Jalan Rsud Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; PDW, Kumala Sari; Astuti, Lelly Winduhani; Suhartatik, Sri; Rimawati, Rimawati; Sari, Eka Kartika
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15671

Abstract

Background: Geriatric patients are elderly people who have various diseases and or problems as a result of diminished organ, psychological, social, economic, and environmental functioning and who require integrated health treatments from a multidisciplinary team. Uncontrolled hypertension can lead to complications such as stroke, CHD, and kidney failure. The more incidence of complications, causing the geriatrics to get more drugs (polypharmacy). Polypharmacy is one of the risk factors for the occurrence of Potentially Inappropriate Medication (PIMs) that often occurs in geriatric patients. The 2019 Beers Criteria is one of the clear criteria that can be used to determine the prevalence of PIMs in geriatric individuals. Objectives: The objective of this study was to see if there was a correlation between the number of drugs administered to hypertensive geriatric outpatients at Dr. Soedomo General Hospital in Trenggalek and the incidence of PIMs. This study employed an observational study with an analytical approach and retrospective. This study included a sample of 85 prescriptions for outpatient geriatric hypertension outpatient at Dr. Soedomo General Hospital in the period October - December 2020 taken using the purposive sampling technique. Data were analyzed using the C contingency coefficient correlation test. Results: 67,1% of prescriptions contained ≥ 5 kinds of drugs and 32,9% of prescriptions contained < 5 kinds of drugs. Based on the incidence of PIMs, there were 97.6% of prescriptions for PIMs and 2.4% of prescriptions without PIMs. The C contingency coefficient correlation test shows the correlation coefficient (r) of 0.216 with a positive direction and p-value = 0.041. Conclusions: The number of drugs has a significant correlation and can cause the incidence of PIMs in geriatric patients with weak correlation strength. Collaboration between pharmacists and doctors is needed to provide the best therapy to patients, to maximize the role of pharmacists in monitoring drug use in geriatric patients at Dr. Soedomo Hospital in Trenggalek.
Pola Penggunaan dan Rasionalitas Obat Stroke Iskemik di RSUD Dr. Saiful Anwar Anikasari, Erni; Widyaningrum, Esti Ambar; Wahyuni, Kumalasari Poespita Dwi; Astuti, Lely Winduhani; Lailatul M., Nur
KUNIR: JURNAL FARMASI INDONESIA Vol 2 No 1 (2024): JULI
Publisher : Program Studi Farmasi (S-1), Fakultas Ilmu Kesehatan, Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/kjfi.v2i1.563

Abstract

Stroke adalah suatu sindrom klinis yang ditandai dengan hilangnya fungsi otak secara akut dan dapat menimbulkan kematian. Serangan iskemia sementara atau Transient ischemic attacks (TIAs) adalah penurunan fungsi iskemia sistem syaraf utama iskemia menurun selama kurang dari 24 jam dan biasanya kurang dari 30 menit. Hal ini terjadi ketika pasokan darah ke otak berkurang atau terhambat karena hal-hal tertentu yang mengarah ke kurangnya kadar oksigen dalam sel-sel otak secara mendadak. Dalam beberapa menit, sel-sel otak bisa rusak dan kehilangan fungsinya. Tujuan dari penelitian ini yaitu untuk mengetahui pola penggunaan obat dan rasionalitas obat pada pasien stroke iskemik yang ditinjau dari parameter tepat diagnosa, tepat indikasi, tepat obat, dan tepat dosis. Penelitian ini dilakukan di RSUD Dr. Saiful Anwar Kota Malang Tahun 2021 dan merupakan penelitian observasional dengan pengambilan data dilakukan dengan secara retrospektif dan dianalisis secara deskriptif. Pengambilan data sebanyak 69 pasien menggunakan metode teknik slovin. Hasil penelitian ini menunjukkan pola penggunaan obat stroke iskemik yaitu kombinasi neuroprotektan + antiplatelet + antihipertensi + antidislipidemia sebanyak 49 pasien. Hasil penelitian rasionalitas obat menunjukkan hasil tepat indikasi 100%, tepat pasien 100%, tebat obat 100%, dan tepat dosis 100%.
Co-Authors Admaja, Wika Anikasari, Erni Astuti, Lelly Winduhani Astuti, Lely Winduhani Badiaturisa Masyriqoh Dewy Resty Basuki, Dewy Resty Dwi Wahyuni Dwitania Noerhalizah Eka Kartika Sari Evi Kurniawati, Evi Fitriani, Marina Herlinda Mawardika Hidayatunnisa, Shafira Indah Sri Hartini Irawati, Renny Nur Satya Irawati, Reny Nur Satya KRISNA KHARISMA PERTIWI Kurniawati, Evi Lailatul M., Nur Lelly Winduhani Astuti Lelly Winduhani Astuti Lestari, Tri Puji Moza Fellya Fadrian Nur Rohmah, Dilla Salwa PDW, Kumala Sari Rilawati, Fentyana Dwi Rimawati, Rimawati Rizky, Fara Nikhmatul Shofiatul Fajriyah Shoviantari, M.Farm., Apt., Fenita Sony Andika Saputra Sri Agustina Sugiyartono, Sugiyartono Suhartatik, Sri Tri Puji Lestari umul farida Wahyuni, Kumala Sari Poespita Dewi Wahyuni, Kumalasari Poespita Dwi Wika Admaja Wika Wika Admaja Wulan, Fitria Wahyuning Yestari, Farah Eka Julia