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Analisis Faktor-Faktor yang Mempengaruhi Kejadian Potentially Inappropriate Medications (PIMs) pada Pasien Geriatri Rawat Inap RSUD Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; Rizky, Fara Nikhmatul; Irawati, Renny Nur Satya; Fajriyah, Shofiatul; Rilawati, Fentyana Dwi; Kurniawati, Evi; Lestari, Tri Puji
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 17 No. 1 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i1.271

Abstract

Background: Geriatric patients are elderly patients with multiple diseases. Geriatric patients have more comorbidities and often receive polypharmacy prescriptions. PIMs have been identified in many elderly patients. One of the explicit criteria that can be used to identify the incidence of PIMs in geriatric patients is the Beers Criteria. Objective: To determine the frequency of PIMs and the factors that can influence the occurrence of PIMs based on the Beers Criteria in hospitalized geriatric patients at RSUD Dr. Soedomo Trenggalek. Method: This research uses a type of research with a retrospective observational analytical approach. The sampling technique used was purposive sampling with a total sample of 312 medical records.  Inclusion criteria: age ≥ 65 years and exclusion: incomplete medical record data. Results: The most common characteristic profiles were male gender (62%), elderly (65-74 years) 69%, type of BPJS service (87%), main disease with the cardiovascular system (31%), number of diseases 2 (43%) and the number of drugs 6-10 drugs (50%). There was an incidence of PIMs of 78.53%. The factors gender, age, type of service, main diagnosis have a p value ≥ 0.05, while the number of diseases and medications have a p value ≤ 0.05. Conclusion: There is an incidence of PIMs in hospitalized geriatric patients of 78.53% with the number of diseases and number of medications influencing the incidence of PIMs in hospitalized geriatric patients.
Analisis Pengaruh Kualitas Layanan Informasi Swamedikasi Online Berbasis Whatsapp Bot Terhadap Kepuasan Masyarakat Widyaningrum, Esti Ambar; Yestari, Farah Eka Julia; Sari, Erni Anika; Srihartini, Indah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1158.686 KB) | DOI: 10.35617/jfionline.v14i2.73

Abstract

Abstract: The innovation of online self-medication information services, one of which is based on WhatsApp Bot, is needed to make it easier for people to find self-medication information for the community. This innovation needs to be continuously developed so that it can provide adequate information services, can increase knowledge and provide satisfaction to users. The purpose of this study was to determine the level of community satisfaction with online self-medication services based on WhatsApp Bot and the effect of expectations on satisfaction using the RATER dimension (Reliability, Assurance, Tangible, Empathy, Responsiveness) in the community of Talun Village, Blitar Regency. The method used in this study is an analytical survey using a cross sectional design. Sampling was done by purposive sampling technique and obtained 264 respondents from the residents of Talun Village, Blitar Regency. Gap analysis was obtained at -0.10 with a level of satisfaction that was not satisfied with the services that had been provided with detailed attributes including: layout, absence of constraints, valid and reliable information, complete information, attention to user needs and the speed of customer service responding, needs to be improved to increase user satisfaction. Spearman rank correlation test obtained P value 0.05 and correlation coefficient value of 0.644. The community is not satisfied with this information service and there is an influence between the quality of information source services and satisfaction in the community of Talun Village, Blitar Regency with a positive correlation and strong correlation strength so it is necessary to develop this Whatsapp Bot-based self- medication information service.
INPATIENT ANTITHROMBOTIC THERAPY FOR MYOCARDIAL INFARCTION : RETROSPECTIVE STUDY Fajriyah, Shofiatul; Nur Rohmah, Dilla Salwa; Astuti, Lelly Winduhani; Rilawati, Fentyana Dwi; Wulan, Fitria Wahyuning; Widyaningrum, Esti Ambar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.762

Abstract

Myocardial infarction (MI), a subtype of coronary heart disease (CHD), is still a major cause of morbidity and mortality around the world. Non-ST-segment elevation MI (NSTEMI) is more common than ST-segment elevation MI (STEMI). Antithrombotic therapy, including antiplatelet and anticoagulant agents, is essential in MI management to prevent thrombus formation and reduce ischemic complications. Although international and national clinical guidelines (PERKI and ACC/AHA) provide recommendations tailored to MI type and patient factors, discrepancies in clinical practice, especially in developing countries, may impact treatment outcomes. This retrospective descriptive study aimed to evaluate the use and appropriateness of antithrombotic therapy in NSTEMI and STEMI patients at Hospital X, Kediri City, in 2018. Data were collected from medical records of hospitalized acute myocardial infarction (AMI) patients. Aspirin combined with clopidogrel was the most commonly used regimen for NSTEMI, whereas STEMI patients frequently received aspirin, clopidogrel, and enoxaparin; fibrinolytics were administered in nine STEMI cases. Dosage evaluation showed compliance with guidelines in NSTEMI patients, while 36.84% of STEMI patients, particularly those receiving enoxaparin, were given incorrect dosages. These findings highlight the need for improved adherence to clinical guidelines to optimize antithrombotic therapy outcomes in MI management
Correlation Between the Number of Drugs Prescribed and Potentially Inappropriate Medication (PIMS) Based on Beers Criteria in Geriatric Hypertension Outpatients at Dr. Soedomo Hospital in Trenggalek: Hubungan Jumlah Obat terhadap Potentially Inappropriate Medication (PIMS) Berdasarkan Beers Criteria pada Pasien Hipertensi Geriatri Rawat Jalan Rsud Dr. Soedomo Trenggalek Widyaningrum, Esti Ambar; PDW, Kumala Sari; Astuti, Lelly Winduhani; Suhartatik, Sri; Rimawati, Rimawati; Sari, Eka Kartika
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15671

Abstract

Background: Geriatric patients are elderly people who have various diseases and or problems as a result of diminished organ, psychological, social, economic, and environmental functioning and who require integrated health treatments from a multidisciplinary team. Uncontrolled hypertension can lead to complications such as stroke, CHD, and kidney failure. The more incidence of complications, causing the geriatrics to get more drugs (polypharmacy). Polypharmacy is one of the risk factors for the occurrence of Potentially Inappropriate Medication (PIMs) that often occurs in geriatric patients. The 2019 Beers Criteria is one of the clear criteria that can be used to determine the prevalence of PIMs in geriatric individuals. Objectives: The objective of this study was to see if there was a correlation between the number of drugs administered to hypertensive geriatric outpatients at Dr. Soedomo General Hospital in Trenggalek and the incidence of PIMs. This study employed an observational study with an analytical approach and retrospective. This study included a sample of 85 prescriptions for outpatient geriatric hypertension outpatient at Dr. Soedomo General Hospital in the period October - December 2020 taken using the purposive sampling technique. Data were analyzed using the C contingency coefficient correlation test. Results: 67,1% of prescriptions contained ≥ 5 kinds of drugs and 32,9% of prescriptions contained < 5 kinds of drugs. Based on the incidence of PIMs, there were 97.6% of prescriptions for PIMs and 2.4% of prescriptions without PIMs. The C contingency coefficient correlation test shows the correlation coefficient (r) of 0.216 with a positive direction and p-value = 0.041. Conclusions: The number of drugs has a significant correlation and can cause the incidence of PIMs in geriatric patients with weak correlation strength. Collaboration between pharmacists and doctors is needed to provide the best therapy to patients, to maximize the role of pharmacists in monitoring drug use in geriatric patients at Dr. Soedomo Hospital in Trenggalek.
Pola Penggunaan dan Rasionalitas Obat Stroke Iskemik di RSUD Dr. Saiful Anwar Anikasari, Erni; Widyaningrum, Esti Ambar; Wahyuni, Kumalasari Poespita Dwi; Astuti, Lely Winduhani; Lailatul M., Nur
KUNIR: JURNAL FARMASI INDONESIA Vol 2 No 1 (2024): JULI
Publisher : Program Studi Farmasi (S-1), Fakultas Ilmu Kesehatan, Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/kjfi.v2i1.563

Abstract

Stroke adalah suatu sindrom klinis yang ditandai dengan hilangnya fungsi otak secara akut dan dapat menimbulkan kematian. Serangan iskemia sementara atau Transient ischemic attacks (TIAs) adalah penurunan fungsi iskemia sistem syaraf utama iskemia menurun selama kurang dari 24 jam dan biasanya kurang dari 30 menit. Hal ini terjadi ketika pasokan darah ke otak berkurang atau terhambat karena hal-hal tertentu yang mengarah ke kurangnya kadar oksigen dalam sel-sel otak secara mendadak. Dalam beberapa menit, sel-sel otak bisa rusak dan kehilangan fungsinya. Tujuan dari penelitian ini yaitu untuk mengetahui pola penggunaan obat dan rasionalitas obat pada pasien stroke iskemik yang ditinjau dari parameter tepat diagnosa, tepat indikasi, tepat obat, dan tepat dosis. Penelitian ini dilakukan di RSUD Dr. Saiful Anwar Kota Malang Tahun 2021 dan merupakan penelitian observasional dengan pengambilan data dilakukan dengan secara retrospektif dan dianalisis secara deskriptif. Pengambilan data sebanyak 69 pasien menggunakan metode teknik slovin. Hasil penelitian ini menunjukkan pola penggunaan obat stroke iskemik yaitu kombinasi neuroprotektan + antiplatelet + antihipertensi + antidislipidemia sebanyak 49 pasien. Hasil penelitian rasionalitas obat menunjukkan hasil tepat indikasi 100%, tepat pasien 100%, tebat obat 100%, dan tepat dosis 100%.
Edukasi Penggunaan Suplemen Selama Pandemi Covid-19 pada Kader Kesehatan di Wilayah Kerja Puskesmas Karangan Kabupaten Trenggalek: Education on the Use of Supplements During the Covid-19 Pandemic for Health Cadres in the Work Area of the Karangan Health Center Trenggalek Regency Widyaningrum, Esti Ambar; Kurniawati, Evi; Lestari, Tri Puji; Pertiwi, Krisna Kharisma
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 6 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i6.5547

Abstract

Several ways can be used to boost the immune system, one of which is by using supplements that can be obtained through a doctor's recommendation or pharmacist consultation. Low immunity in humans will make it easy to be exposed to diseases or viruses, including quickly exposure to Covid-19. This is why many people take supplements: they think the amount of minerals and vitamins they get from their food is insufficient to keep their immune system healthy. One of the considerations for taking supplements is knowledge of their benefits. Even though supplements are not drugs, their use must also be rational. Individuals with adequate knowledge, especially about supplements, will tend to choose and use supplements according to conditions and benefits for the body. To find out the effectiveness of counseling in increasing knowledge of the use of supplements to increase body immunity during the Covid-19 pandemic for health cadres in the Karangan Health Center, Trenggalek Regency working area. This community service is conducted through lectures and question-and-answer method counseling. The number of participants in this activity was 33 health workers in the work area of the Karangan Health Center, Trenggalek Regency. Results: There was an increase in knowledge of the use of immunity-boosting supplements in health cadres in the work area of the Karangan Health Center, Trenggalek Regency, from the majority of sufficient knowledge (pre-test) to good (post-test). Education on using supplements can increase the knowledge of health cadres in the work area of the Karangan Health Center.
Gerakan Opimba (Orang Tua Pintar Minum Obat): Penyuluhan dan Kaderisasi Orang Tua Cerdik dan Cermat dalam Penggunaan Obat Cair Shoviantari, M.Farm., Apt., Fenita; Saputra, Sony Andika; Kurniawati, Evi; Widyaningrum, Esti Ambar; Lestari, Tri Puji; Pertiwi, Krisna Kharisma; Sugiyartono, Sugiyartono; Mawardika, Herlinda
Journal of Community Engagement and Empowerment Vol. 6 No. 1 (2024)
Publisher : Institut Ilmu Kesehatah Bhakti Wiyata Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Obat yang berbentuk liquida atau obat cair merupakan obat yang banyak digunakan oleh anak – anak dan juga lansia atau pasien yang memiliki kesulitan untuk menelan obat padat. Obat ini dianggap lebih praktis dan tepat dalam dosis penggunaannya karena dilengkapi dengan sendok takar sehingga dosis yang dapat diberikan lebih variatif bergantung pada kondisi pasien. Sebuah survei yang dilakukan terhadap pasien yang sedang menunggu di ruang tunggu dokter menunjukkan bahwa 73 persen pasien menggunakan sendok makan atau sendok teh untuk mengukur dosis obat cair, bukan menggunakan sendok/mangkuk ukur yang biasanya diberikan bersama obat cair. Pengukuran menggunakan sendok makan atau sendok teh yang sangat tidak akurat dapat menyebabkan masalah, seperti terlalu banyak atau terlalu sedikitnya obat yang dikonsumsi. Untuk itu, penting sekali untuk memberikan edukasi kepada Masyarakat mengenai pentingnya menggunakan sendok atau gelas takar yang disediakan di dalam kemasan obat Ketika menggunakan obat cair. Pengabdian Masyarakat yang bekerja sama dengan Sekolah Islam Terpadu (SIT) Permata Ummat Trenggalek ini memberikan materi mengenai macam sediaan cair, cara penggunaan obat cair, cara membaca brosur obat cair, dan cara pemusnahan obat cair. Kegiatan pengabdian diawali dengan pre test dan diakhir dengan post test untuk mengukur pengetahuan Masyarakat sebelum dan sesudah mengikuti kegiatan pengmas. Dari hasil evaluasi pre dan post test didapatkan peningkatan pengetahuan peserta sebelum dan sesudah mengikuti kegiatan penyuluhan.
Peningkatan Pengetahuan Masyarakat Tentang Penggolongan Obat Dan Beyond Use Date (BUD) Melalui Penyuluhan pada kader siaga Lestari, Tri Puji; Kurniawati, Evi; Widyaningrum, Esti Ambar; Pertiwi, Krisna Kharisma; Basuki, Dewy Resty
Journal of Community Engagement and Empowerment Vol. 6 No. 1 (2024)
Publisher : Institut Ilmu Kesehatah Bhakti Wiyata Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Untuk menjaga mutu dan kualitas obat, maka pengelolaan terhadap obat itu sendiri sangat memberikan peran yang vital. Salah satunya adalah dengan mengetahui batas masa kadaluarsa dan penggolongan obat maka akan memudahkan masyarakat untuk menentukan waktu dan metode penyimpanan . Tanggal kadaluarsa obat yang sudah dibuka dapat berbeda dengan yang tertera pada kemasan yang berlaku untuk sediaan baik sediaan steril maupun non steril dimana ketika melewati batas tanggal tersebut maka sediaan yang dimaksud tidak boleh digunakan dan disimpan. Kegiatan pengabdian Masyarakat dilaksanakan di periode bulan desember 2022 pada kader siaga desa di kecamatan karangan, kabupaten trenggalek, Jawa Timur. Metode yang digunakan dalam pengabdian masyarakat ini menggunakan metode pre dan post test juga diikuti dengan kegiatan konseling. Instrumen yang digunakan adalah dengan pemberian quesioner baik pada waktu pre test maupun post test , peserta juga diberi leaflet materi tentang penggolongan obat dan beyond use date (BUD). Konseling diberikan dalam waktu 3 hari setelah sosialisasi menggunakan media watshap. Dari kegiatan pengabdian masyarakat ini didapatkan ada kenaikan prosentase pengetahuan yang cukup signifikan. Dimana datap dilihat pada tabel 1 bahwa rata-rata pengetahuan kader ada kenaikan dari 54,9% menjadi 92,5%.
Tinjauan Pustaka Mengenai Edukasi Pasien Oleh Apoteker Dalam Penggunaan Obat Rasional Widyaningrum, Esti Ambar; Anikasari, Erni; Rilawati , Fentyana Dwi
Sciences and Clinical Pharmacy Research Journal Vol. 2 No. 4 (2026): January
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/scpr.v2i4.5073

Abstract

Kajian ini bertujuan menelaah secara komprehensif peran edukasi pasien oleh apoteker dalam mendukung praktik penggunaan obat rasional. Penelitian dilakukan dengan pendekatan kualitatif melalui studi pustaka terhadap sepuluh artikel ilmiah yang relevan dan terbit antara tahun 2010 hingga 2025. Proses penelusuran literatur mengikuti pedoman Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Pencarian dilakukan melalui basis data internasional, termasuk PubMed, ScienceDirect, dan SpringerLink. Dari total 139 artikel yang teridentifikasi, 25 artikel dihapus karena duplikasi dan 5 dinilai tidak layak secara otomatis, sehingga tersisa 109 artikel untuk proses penyaringan lebih lanjut. Setelah seleksi mendalam berdasarkan kriteria inklusi dan eksklusi, hanya 10 artikel yang memenuhi kriteria dan dijadikan dasar analisis. Data dianalisis secara tematik untuk mengidentifikasi pola kontribusi edukasi apoteker terhadap perilaku penggunaan obat rasional. Hasil analisis menunjukkan bahwa edukasi yang diberikan apoteker berperan signifikan dalam meningkatkan kepatuhan terapi, mengurangi kesalahan penggunaan obat, serta meningkatkan efisiensi biaya kesehatan. Pendekatan edukasi kolaboratif yang berpusat pada pasien terbukti lebih efektif dibandingkan penyampaian informasi satu arah. Temuan ini menguatkan konsep dalam Pharmaceutical Care dan Health Belief Model, terutama mengenai pentingnya komunikasi terapeutik dalam memfasilitasi pengambilan keputusan pasien yang aman, efektif, dan berkelanjutan terkait penggunaan obat.