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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Martabe : Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) AL-ULUM: JURNAL SAINS DAN TEKNOLOGI Jurnal Dunia Farmasi Jurnal Ilmu Kesehatan Jurnal Riset Kefarmasian Indonesia Ahmar Metastasis Health Journal (AMHJ) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Triswanto Sentat
Sekolah Tinggi Ilmu Kesehatan Samarinda
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Energy Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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UJI AKTIVITAS EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus) Triswanto Sentat; Rizki Permatasari
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v1i2.20

Abstract

Activity Assay of avocado leaf (Persea americana Mill.) ethanol extract on burn healing at back skin of white male mice (Mus musculus) aims to determine the best concentration of avocado leaf ethanol extract to healing burn on back skin of mice. Extract of avocado leaf obtained by maceration method using ethanol 70%. Burn made by soldering iron modified with square plate (size 1 x 1 cm2), during 2 seconds contact at the skin and make the skin formed blister. Observation of the burn area was doing daily for 14 days, and also the treatment with the 3 concentrations extract variation (20%,35%, and 50%), negative control and positive control. Result of research show that all avocado leaf ethanol extract in concentrations 20%, 35% and 50% have good activity in burn healing, from first day until 14th day they showed percentage of burn recovering successively equal to 86%, 88% and 90%. Negative control showed that process healing of burn was very tardy, only has percentage of burn recovering equal to 32,67% on 14th day, while positive control showed 100% burn healing on 11st day. The best concentration of  avocado leaf ethanol extract on healing burn is 50% with 90% burn healing
UJI EFEK ANALGESIK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) PADA MENCIT PUTIH JANTAN (Mus musculus) DENGAN INDUKSI NYERI ASAM ASETAT Triswanto Sentat; Susiyanto Pangestu
Jurnal Ilmiah Manuntung Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i2.59

Abstract

Kersen leaf (Muntingia calabura L.) contains tannins, flavonoids and polyphenol compounds allegedly have analgesic effect. The objective was to determine the analgesic effect of ethanol extract of kersen leaves and to determine the most effective analgesic dose. This study was an experimental research. Leaves were extracted with ethanol 70% and the analgesic effect test was divided into 5 groups: negative control treatment (distilled water), positive control (mefenamic acid 2.6mg/kg), kersen leaf ethanol extract first dose (100mg/kg), second dose (200mg/kg) and tthird dose (400mg/kg). Giving treatments by oral, after 30 minutes, the mices were given a pain inductor with 0.5% acetic acid by intra peritonial administration. Analgesic power was calculated by counting the number of writhing in mice for 1 hour. The results showed that the ethanol extract of cherry leaf has analgesic effect. From the calculation of the first dose analgesic power (42.9%), second dose (59.4%) and the third dose 69.9%. Statistical test results kruskal wallis value of p=0.011 (p<0.05) showed a significant difference between all analgesic treatment groups. The conclusion of this study is all of the ethanol extract had analgesic effects on male white mice, whereas a dose of 400mg/kg is the most effective analgesic dose.
HUBUNGAN PELAYANAN INFORMASI OBAT TERHADAP KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI RSUD PENAJAM PASER UTARA Triswanto Sentat
Jurnal Ilmiah Manuntung Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i1.85

Abstract

The Drug Information Service or Pelayanan Informasi Obat (PIO) is indispensable for improving patient compliance with their treatment. With the PIO can change the knowledge and compliance of patients, especially hypertensive patients. This study was conducted to determine whether PIO can influence adherence to medication hypertension patients in RSUD Penajam Paser Utara. Sampling was done by purposive sampling and analyzed using Spearman Rank Correlation Test where the compliance aspect was assessed using validity and reliability tested questionnaire method, given before PIO and after PIO, and Pill Count method (calculating the remaining pills for 4 weeks) . Samples were obtained by 50 people, the results showed no improvement in adherence before and after PIO administration, and there was a relationship of compliance measurement results with questionnaire method after counseling and Pill Count method. The percentage of patient adherence after PIO administration was based on a high-compliance 70% (35 person) questionnaire method and based on the Pill Count method with a high adherence rate of 60% (30 persons), the compliance data obtained from both methods indicated that the provision of PIO can not improve compliance to take medication of hypertension patient of RSUD Penajam Paser Utara
EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA Rusdiati Helmidanora; Triswanto Sentat
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.126

Abstract

More than two-thirds of patients with type 2 diabetes also experience hypertension whose development coincides with hyperglycemia, where each disease has a tendency to influence the increased risk of other diseases. Sundry new guidelines, such as the National Joint Committee 8, the American Diabetes Association recommend blood pressure targets in the diabetic population of <140/90 mmHg to reduce cardiovascular risk and prevent the progression of nephropathy. This study aims to determine whether there is a difference in achieving blood pressure target < 140/90 mmHg according to Join National Committee 8 between ACEi and ARB in patients with type 2 diabetes with hypertension. This research was conducted using a retrospective at internist clinic of Abdul Wahab Syahranie hospital, by taking secondary data from the medical record from blood pressure o 49 outpatients received a single antihypertensive either drug ACEi 29 people or ARB 34 people. This study showed that the achievement of target blood pressure by <140/90 mmHg (JNC 8 guideline) between ACEi 7 (28%) and ARB 5 (20,8%) group and it can be concluded that between ACEi and ARB drugs(P=0.5) there was no differsignificantly in achievement blood pressure target on type 2 diabetes with hypertension.
PEMBUATAN STRIP TEST DAN IDENTIFIKASI FENILBUTAZON PADA JAMU PEGAL LINU Henny Nurhasnawati; Triswanto Sentat; Adi Prasetiyo
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.383

Abstract

Jamu (Indonesian herbal medicine) are prohibited from containing chemicals medicine which are isolated or synthetic chemical compounds. Chemical compounds which is commonly added in jamu pegal linu (rheumatic pain) is phenylbutazone. One simple alternative test for detecting chemicals medicine content is to use a strip test. The purpose of this study was to determine the presence or absence of phenylbutazone content in jamu using a strip test. The research conducted is experimental research. This study used 6 samples of jamu pegal linu which were extracted using 95% ethanol solvent. The strip test is carried out by immobilizing reagents into Whatman’s filter paper using the impregnation method. Data obtained from observations of the color change of the strip test. The results showed that strip test made with alizarin red reagent and potassium hexacyanoferate (III) identified 2 samples of jamu pegal linu containing phenylbutazone, namely sample D and E, from 6 samples that circulated in Sungai Pinang District, Samarinda.
A Quantitative Study Assessment of Public Knowledge Regarding Self-Medication with Ibuprofen In Marang Kayu District: A Quantitative Study Sentat, Triswanto; Nurjannah, Ika; Jubaidah, Siti; Wijaya, Heri; Helmidanora, Rusdiati
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 1 (2025): J Sains Farm Klin 12(1), April 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.1.72-80.2025

Abstract

Self-medication is an approach widely used by the public to treat mild pain symptom by using over-the-counter medications without a prescription from physician. One of the medications that can be used for self-medication is Ibuprofen. Ibuprofen is a drug that can be used for self-medication; however, its use should be under the supervision and guidance of healthcare professionals. This study aims to determine the level of public knowledge regarding the self-medication use of ibuprofen in Marang Kayu District. This research uses a quantitative design with a descriptive approach. Data were collected through questionnaires distributed to 369 respondents selected using purposive sampling. The questionnaire included questions about knowledge aspects regarding ibuprofen and self-medication patterns. The study results showed that the level of public knowledge in Marang Kayu District about Ibuprofen for self-medication was 14.5% (49 respondents) with a high level of knowledge, 31.3% (106 respondents) with a moderate level of knowledge, and the majority, 54.3% (184 respondents), with a low level of knowledge. The results underscore the urgent need for targeted health education programs to improve public awareness and promote safe self-medication practices. Enhancing community knowledge is essential to minimize the risks associated with improper ibuprofen use and to encourage responsible drug consumption
BIMBINGAN TEKNIS PEMBUATAN HAND SANITIZER DARI BAHAN SINTETIS DAN ALAMI DI KELURAHAN TELUK LERONG ILIR DAN SIDODADI KECAMATAN SAMARINDA ULU Handayani, Fitri; Sentat, Triswanto; Fatimah, Nurul
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 1 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i1.241-245

Abstract

Melonjaknya penyebaran virus SARS-CoV-2 mengakibatkan harga hand sanitizer di Kalimantan Timur melonjak tinggi bahkan terjadi kekosongan stok hand sanitizer di pasaran baik pertokoan maupun fasilitas kesehatan. Tujuan Bimbingan Teknis (BimTek) pembuatan hand sanitizer dari bahan sintetis dan alami adalah peningkatan masyarakat mandiri yang inovatif dan kreatif di tengah masa pandemi Covid-19 hingga menuju kehidupan New Normal dalam menyikapi harga yang melonjak tinggi dan kekosongan stok hand sanitizer. Metode pelaksanaan bimbingan teknis ini dilakukan dengan penyampaian materi dan diskusi kepada peserta tentang definisi hand sanitizer, alat yang digunakan, komposisi bahan sintetis dan alami, cara pembuatan hand sanitizer berbahan sintetis dan alami, pengemasan dan  estimasi biaya yang dibutuhkan dalam pembuatannya. Hasil dari kegiatan BimTek ini menunjukkan bahwa peserta perwakilan dari Kelurahan Teluk Lerong dan Sidodadi Kecamatan Samarinda Ulu dalam Kegiatan BimTek dapat membuat hand sanitizer dari bahan sintetis dan alami dengan baik dan benar sesuai standar WHO dan penelitian sebelumnya yang sudah terpublikasi dalam jurnal ilmiah. 
PENGARUH DUKUNGAN KELUARGA TERHADAP KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI PUSKESMAS MUARA WIS Sri Endah Handayani; Husnul Warnida; Triswanto Sentat
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.527

Abstract

One of the public health concerns is drug non-adherence. The main cause of poor hypertension control is noncompliance with antihypertensive medications. The elements that drive compliance behavior are numerous and complicated, with social support being one of them. Family support is critical in health care since it is through family support that a healthy family can be achieved. Family members can help by providing information about their sickness or reminding them to take their medications. The goal of this research was to identify the relationship between family support and medication adherence in hypertensive patients at Muara Wis Health Center, Kutai Kartanegara Regency, Province East Borneo. This study is descriptive correlational and uses a cross-sectional method, which involves measuring or observing at the same time and the same location. The participants in this study were 100 hypertensive patients of Muara Wis Health Center. The data in this study were analyzed using Spearman rank correlation. Based on the MMAS (Morisky Medication Adherence Scale) questionnaire, medication adherence in hypertensive patients at the Muara Wis Health Center had 52 percent low adherence, 29 percent moderate adherence, and 19 percent high adherence. According to pill count, low adherence patients was 51 percent, moderate adherence was 29 percent, and high adherence was 20 percent. Patients with hypertension who had poor family support were 54 percent, those who received moderate family support were 26 percent, and those who received strong family support were 20 percent. Hence, there is a significant relationship between family support and medication adherence in hypertensive patients of Muara Wis Health Center.
OPTIMALISASI FARMAKOTERAPI: IDENTIFIKASI DAN EDUKASI TENTANG ADRs DAN DRPs PADA PESERTA PROLANIS WILAYAH PUSKESMAS SURIAN, KABUPATEN SOLOK, SUMATERA BARAT Gumala, Azhoma; Armenia, Armenia; Prima Putra, Deddi; Syafni, Nova; Handayani, Fitri; Eka Putri, Desi; Furqan, Mainal; Sentat, Triswanto; Gusnelti, Yessi; Lucida, Henny
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 9, No 1 (2026): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v9i1.%p

Abstract

Peningkatan risiko reaksi obat yang tidak diinginkan (adverse drug reactions/ADRs) dan masalah terkait obat (drug-related problems/DRPs) pada pasien penyakit kronis, khususnya peserta Program Pengelolaan Penyakit Kronis (PROLANIS), sangat membutuhkan informasi dan edukasi intensif terkait optimalisasi terapi. Kegiatan pengabdian ini bertujuan untuk mengidentifikasi insiden ADRs dan DRPs pada kelompok PROLANIS di Puskesmas Surian dan memberikan edukasi yang terfokus untuk meminimalkan risiko, demi mencapai terapi optimal. Kegiatan diawali dengan wawancara dan pengumpulan data kuesioner dari 30 responden (semua perempuan). Hasil demografi menunjukkan mayoritas responden (70,00%) berusia 45–64 tahun, dan dua pertiga (66,67%) mengalami polifarmasi (menderita 3–7 penyakit kronis). Empat penyakit utama yang diderita adalah artritis, hipertensi, hiperurisemia, dan dislipidemia. Penting untuk dicatat, 60% responden melaporkan keluhan yang mengindikasikan ADRs dan DRPs. Sebagian besar subjek memperoleh obat dari tenaga kesehatan formal (86,67%). Tindak lanjut kegiatan mencakup pemeriksaan kesehatan gratis (tekanan darah, gula darah, kolesterol, dan asam urat) serta konseling langsung. Pasien PROLANIS menerima edukasi mendalam tentang cara penggunaan obat yang benar, terutama dalam terapi polifarmasi, untuk meminimalkan masalah terkait obat. Disimpulkan bahwa edukasi intensif dan berkelanjutan mengenai obat-obatan, pengobatan alternatif, dan suplemen kesehatan kepada komunitas PROLANIS sangat penting. Intervensi ini secara signifikan berkontribusi pada keselamatan pasien dan meningkatkan pemahaman masyarakat dalam pengelolaan penyakit kronis.
ANTIDEPRESSANT ACTIVITY TEST OF RED BETEL LEAF ETHANOL EXTRACT (Piper crocatum) ON MALE WHITE MICE (Mus musculus) USING THE FORCED SWIM TEST METHOD Triswanto Sentat; Anita Apriliana; Siti Lili Rizki Sari; Novi Milasari; Ghina Adhila; Rizki Rahmadi Pratama; M. Hasan Andryanto
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 11, No 2 (2025)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v11i2.18542

Abstract

Red betel leaves (Piper crocatum) contain flavonoids, alkaloids, polyphenols, tannins, and which is known for its antidepressant properties. The purpose of this study was to determine the effect of antidepressant activity of ethanol extract of red betel leaves on male white mice (Mus musculus) orally. The method used in testing antidepressants is the Forced Swim Test. Fifteen mice were divided into five groups: a positive control group receiving 3.5 mg/kg BW amitriptyline, a negative control group, and three groups receiving 200, 400, and 800 mg/kg BW of the extract. The antidepressant effect was measured by observing the immobility of mice during swimming. The results of the study using paired sample t-Test analysis showed that there was a difference in immobility before and after, in the 400 mg/kg BW extract and 3.5 mg/kg BW amitriptyline dose groups had significant differences.
Co-Authors Abdul Rahim Adi Prasetiyo Anita Apriliana Armenia, Armenia Azhoma Gumala Eka Kumalasari Eka Putri, Desi Ellen Indraswari Endah Handayani Fitri Handayani Fitri Handayani Fitri Handayani Furqan, Mainal Ghina Adhila Gusnelti, Yessi Henny Lucida Henny Nurhasnawati Heri Wijaya, Heri Husnul Warnida Husnul Warnida Husnul Warnidah Ika Nurjannah, Ika Lukman Nul Hakim M. Hasan Andryanto Nova Syafni Novi Milasari Nurul Fatimah Nurul Fatimah Pangestu, Susiyanto Prima Putra, Deddi Rakhmadhan Niah Reksi Sundu Risa Supriningrum Rizki Permatasari Rizki Rahmadi Pratama Rusdiati Helmidanora Siti Jubaidah, Siti Siti Lili Rizki Sari Sri Endah Handayani Susiyanto Pangestu Syamsiar, Syamsiar Warnida, Husnul Wiwid Verri Yanti Yanti, Wiwid Verri Yulistia Budianti Yullia Sukawaty Yunita Rachma Dwinand