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All Journal E-Jurnal Medika Udayana Jurnal Farmasi Klinik Indonesia Journal of Economic, Bussines and Accounting (COSTING) YUME : Journal of Management Jurnal Biomedika dan Kesehatan Jurnal Manajemen dan Administrasi Rumah Sakit Indonesia (MARSI) Medika Kartika : Jurnal Kedokteran dan Kesehatan Community Engagement and Emergence Journal (CEEJ) Jurnal Ners AKSELERASI: Jurnal Ilmiah Nasional Journal of Humanities, Social Science, Public Administration and Management (HUSOCPUMENT) Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Jurnal MedScientiae Jurnal Kedokteran Meditek Maneggio Indonesian Journal of Biomedicine and Clinical Sciences Jurnal Bioteknologi & Biosains Indonesia (JBBI) J-CEKI Jurnal Ekonomi, Manajemen, Akuntansi Jurnal Bioteknologi & Biosains Indonesia
Wani Devita Gunardi
Universitas Kristen Krida Wacana
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Journal : Jurnal MedScientiae

 1 
Efektivitas Efektivitas Toilet Seat Sanitizer terhadap Bakteri Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase: Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase Pasaribu, Donna Mesina; Gunardi, Wani Devita; Andini , Natasya Johanna
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3745

Abstract

The toilet is one of the facilities provided to meet the needs of users with various backgrounds of different hygiene behavior, so that they can be a source of bacterial transmission, one of which is Escherichia coli (E.coli), which is resistant to producing Extended-Spectrum Beta-Lactamase (ESBL). E.coli producing ESBL can cause infection of various diseases, to overcome this, preventive measures are taken to reduce the level of risk transmission through the use of toilet seat sanitizers. This study aims to determine the effectiveness of toilet seat sanitizer against E.coli producing ESBL. This research is a descriptive observational laboratory study using a toilet seat sanitizer with an active substance of 50%-Benzalkonium Chloride and Ethyl Alcohol 96% against E.coli producing ESBL American Type Culture Collection (ATCC) 35218. The phenol coefficient test was used to measure the effectiveness of the toilet seat sanitizer was compared with phenol, Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) were tested using the tube method. This study showed that the coefficient of toilet seat sanitizer effective against E.coli producing ESBL was 4,5. MIC active substance toilet seat sanitizer is effective at a concentration of 0,3125%, and MBC at a concentration of 0,625%. The author concludes that the results of the MIC and MBC prove that a toilet seat sanitizer active substances 50%-Benzalkonium Chloride and Ethyl Alcohol 96% is effective as a disinfectant against E.coli producing ESBL ATCC 35218.
Pola Kepekaan Antibiotik Fosfomycin terhadap Bakteri Patogen Penyebab Infeksi Saluran Kemih Pasien Dewasa di Rumah Sakit X pada Periode Tahun 2023 Ebat, Aelred Parleso; Gunardi, Wani Devita; Pasaribu, Donna Mesina Rosadini
Jurnal MedScientiae Vol. 4 No. 3 (2025): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i3.3618

Abstract

Urinary Tract Infection (UTI) is an infection of the urinary tract structure which is generally caused by Escherichia coli with a prevalence of 5-15% with an estimated 180 thousand cases per year in Indonesia, making it the most common disease today. This is further exacerbated by increasing resistance to conventional antibiotics such as amoxicillin, cephalosporins, and fluoroquinolones which makes the selection of UTI therapy increasingly difficult. This study aims to determine the sensitivity of fosfomycin antibiotics to pathogens that cause UTI in adult patients at Hospital X in the period 2023. This study used an observational method, with a retrospective descriptive approach by collecting and analyzing secondary data from the microbiology laboratory of Hospital X. The sampling technique used total sampling with a sample size of 51. Using univariate analysis, it was found that women and the elderly group had a fairly high risk of UTI, with E. coli being the most common etiology (51.8%). Fosfomycin was shown to have a high level of sensitivity (96.55%) to E. coli. Therefore, it can be concluded that fosfomycin has a high level of sensitivity to pathogens that cause UTI infections in adult patients at Hospital X in 2023. This study will be more accurate if the number of samples can be increased again.
Co-Authors Ade Dharmawan Andini , Natasya Johanna Antoni, Marcel Astrid, Mariana Berlianti Bulovannelisa Meykward Salamahu Bernard T. Widjaja Dalton Ngangi Devita, Arleen Dewi, Vica Christia Diana Wijaya Donna Mesina Rosadini Pasaribu Donna Mesina Rosadini Pasaribu Ebat, Aelred Parleso Eka Desy Purnama Eka Desy Purnama Eka Desy Purnama Elisabeth D. Harahap Erma Mexcorry Sumbayak Ernawaty Tamba Eva Oktavia Eva Oktavia, Eva Evan Luke Aditya Evrilia Trihandayani Fushen Fushen Fushen Fushen, Fushen Gratia Erlinda Tomasoa Handy Winata Hansel Sanchia Haq, Satria Addienul Haryono, Budi Hikmah, Dian Nurul Ivan Yoseph Saputra Jannah, Ega Farhatu Kintan Utami Kris Herawan Timotius Layanto, Nicolas Lepianda, Jessica Mahardik, Ngakan Made Ari Margaretha MH, Fushen Mohamad Yanuar Prasetyo Nugroho Monica Puspa Sari Muhammad Faturrahman Adani Muhammad Nazmi Nazmi, Muhammad Ngakan Made Ari Mahardik P.M Budi Haryono Pasaribu, Donna Mesina PM. Budi Haryono Restu Aritonang Rina, Veronica Samantha Saparso Saputra, Ivan Yoseph Sari, Monica Puspa Simon, Flyndie Soegeng Wahyoedi Sudradjat, Susana Elya Tania, Rada Teiseran, Virginia Marsella Tintin Supriatin Utami, Kintan Widjaja, Bernard Tirto Widya Widya