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Uji Aktivitas Antibakteri Senyawa Flavonoid dari Rimpang Temu Kunci (Kaempferia pandurata Roxb.) terhadap Streptococcus mutans Handayani, Siti; Mursiti, Sri; Wijayati, Nanik
Indonesian Journal of Chemical Science Vol 7 No 2 (2018)
Publisher : Indonesian Journal of Chemical Science

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Abstract

Fingerroot (Kaempferia pandurata Roxb.) is one other from varient traditional medicine plant was many grow in Indonesia. This plant had many compounds of secondary metabolite that used for antibacterial. The other one bacterial causing tooth plaque was tooth and mouth diseases which many alert by Indonesians. The most roling bacterial in causing it is Streptococcus mutans. The study aims to determine isolation flavonoid compound and the activity to inhibit bacterial growth. The compound obtained with isolates the fingerroot using coloumn chromatography was extracted with maseration method. Coloumn chromatography result analized with UV-Vis and FTIR spectrofotometre. Antibacterial activity method is agar difusion using paper disk. The results showed that isolation compound is flavanone, that is 6.7.3’.4’-tetrahidroxy flavanone. Activity showed that flavanone is resistent against Streptococcus mutans and have lower activity than ethanol extract samples amount 1.85 mm.
PENGARUH MODEL PEMBELAJARAN INQUIRY TRAINING BERBANTU MEDIA PEMBELAJARAN AUDIOVISUAL FISIKA TERHADAP HASIL BELAJAR SISWA SMA Sani, Ridwan A; Handayani, Siti
JURNAL IKATAN ALUMNI FISIKA UNIVERSITAS NEGERI MEDAN Vol 4, No 2 (2018): JURNAL IKATAN ALUMNI FISIKA UNIMED EDISI APRIL - JUNI 2018
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jiaf.v4i2.10911

Abstract

Penelitian bertujuan untuk mengetahui pengaruh model pembelajaran inquiry training berbantu media pembelajaran audiovisual fisika dan pembelajaran konvensional terhadap hasil belajar siswa SMA.Jenis penelitian adalah quasi experiment dengan teknik pengambilan sampel secara cluster random sampling. Populasi dalam penelitian adalah seluruh siswa kelas X semester II yang terdiri dari dua kelas. Sampel yang dipilih adalah kelas X MIA FD A sebagai kelas eksperimen dengan model pembelajaran inquiry training berbantu media pembelajaran audiovisual fisika yang berjumlah 30 orang dan kelas X MIA 3 sebagai kelas kontrol dengan model pembelajaran konvensional yang berjumlah 30 orang. Instrumen yang digunakan dalam penelitian adalah tes pilihan berganda sebanyak 15 soal yang telah divalidkan. Berdasarkan hasil uji hipotesis dengan menggunakan uji t diperoleh kesimpulan bahwa ada perbedaan akibat pengaruh penggunaan model pembelajaran inquiry training berbantu media pembelajaran audiovisual fisika terhadap hasil belajar siswa SMA.
Revisited Anterolateral Thigh Free Flaps For Reconstructive Microsurgery : One Year Evaluation Atmodiwirjo, Parintosa; Handayani, Siti; Djaprie, Shelly Madona
Jurnal Plastik Rekonstruksi Vol. 1 No. 2 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (770.194 KB) | DOI: 10.14228/jpr.v1i2.44

Abstract

Extensive soft tissue defects present a dif!cult problem to the plastic surgeon as they are usually associated with exposed important structures such as vessels, nerves, tendons, joint cavity or bone. Reconstruction of soft tissue defects have a wide range of therapeutic options. We reconstructed soft tissue defect in many areas using free anterolateral thigh flap (ALTF). From Februari 2009 - 2010, 9 cases of soft tissue defects in the face, neck, leg and foot of various etiologic factors were admitted to the plastic and reconstructive surgery unit, Cipto Mangunkusumo general hospital. Trauma is the commonest cause of soft tissue defects of the lower extremity, followed by tumours. The cruris was the commonest site (4 cases, 44,4%). Flap success rate was 66,67 %. Failure was reported 1 cases in this study due to vein compromise. In our hospital, we are quite familiar with Anterolateral thigh flap (ALTF) even though the case is limited. Anterolateral thigh flap (ALTF) is used for reconstruction of various simple and complex soft tissue defects, for big and small defects with cavity (orbita).
Speech Outcome Evaluation After Two-Flap Palatoplasty In Plastic Surgery Division Cipto Mangunkusumo Hospital: A Retrospective study Bangun, Kristaninta; Handayani, Siti; Djoenaedi, Intania; Wahyuni, Luh Karunia
Jurnal Plastik Rekonstruksi Vol. 1 No. 2 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (620.028 KB) | DOI: 10.14228/jpr.v1i2.49

Abstract

One of the primary goal of cleft palate repair is to provide an intact mechanism for normal speech production. The purpose of this study is to evaluate the two-flap mucoperiosteal palatoplasty procedure on speech outcomes in patients undergoing surgical repair before the age of 2 years. A retrospective analysis study was done on 22 children with complete unilateral cleft palate (with or without cleft lip) who underwent two-flap palatoplasty between year 2002 to 2006 at Cipto Mangunkusumo Hospital. Evaluation was performed by a speech pathologist for pattern of articulation, hypernasality, intelligibility, and velopharyngeal competence. Palatoplasty were performed after 2 year-old in 11 patients and before 2 year-old in 11 patients. Speech of the 22 children postpalatoplasty was evaluated perceptually from standardised tape recordings. Velopharyngeal competence in patients who underwent palatoplasty before 2 year-old compared to after 2 year-old were 72.7% good, 18.2% fair and 9.1% poor versus 54,5% good, 9,1% fair and 36,4% poor respectively. Two-flaps mucoperiosteal palatoplasty performed before the age of 2 years old shows better spepolech outcome in all parameters, although the numbers are not statistically significant. Further prospective study with larger sample is needed.
Amniotic Band Sequence, Frequently Misdiagnosed in Cleft Patients Putri, Nandita Melati; Handayani, Siti; Bangun, Kristaninta
Jurnal Plastik Rekonstruksi Vol. 1 No. 3 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (491.217 KB) | DOI: 10.14228/jpr.v1i3.58

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Background: Amniotic band sequence (ABS) is a set of congenital malformations attributed to amniotic bands that entangle fetal parts during intrauterine life. thiopatogenesis of this sequence is still unknown. Because of such a wide spectrum of possible anomalies and many combinations of their simultaneous appearance, there are no two identical cases of ABS. This diagnosis is often missed based on the secondary major defects.Patients and Methods : There are cases of cleft patients treated in Plastic Surgery Division Cipto Mangunkusumo Hospital that has other congenital anomalies. The data is taken from the medical record and surgical photos (in our division from 2010-2011). Results : The patients presented had either facial cleft or cleft lip and palate. These patients had other congenital anomalies such as meningoencephalocele and constriction ring syndrome or other defects on the extremities.Summary : This diagnosis may not be often established because we often only see the secondary major defects such as meningoencephalocele or facial cleft. With this paper we hope that we could make this diagnosis known so we can make a multidisciplinary approach to this sequence.
Maxillary Growth Evaluation After Cleft Palate Repair Using Goslon Criteria: Preliminary Study Simamora, Huntal; Lamtiur, Evie; A., Nur; Handayani, Siti; Bangun, Kristaninta
Jurnal Plastik Rekonstruksi Vol. 1 No. 3 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (477.047 KB) | DOI: 10.14228/jpr.v1i3.67

Abstract

Background: The goal of palatoplasty is to achieve normal maxillofacial growth, normal speech, and prevent hearing loss. Disturbance of maxillary growth may occur in cleft lip palate patients after palatoplasty. To determine how many patients later developed a disrupted maxillary growth following operations, a retrospective study was designed to evaluate patients with complete unilateral cleft lip and palate who have undergone two-flap palatoplasty.Methods:A retrospective analytic study evaluated the maxillary growth of 15 consecutive unilateral cleft lip and palate patient aged around 8-year-old treated in the Division of Plastic Surgery Cipto Mangunkusumo Hospital, Jakarta. Cephalogram and dental study models were used to assess growth. Cleft lip and palate repair were performed to all patients without alveolar bone graft or any orthodontic treatment. Result: The cephalogram shows that 53,3% of the patients developed maxillary hypoplasia post palatoplasty. Mean value of the Goslon Yardstick was 3,53 (intermediate category by Goslon criteria).No patient fell into the Goslon 1 or 5 categories. Discussion: Disturbed maxillary growth is postulated to be caused by the manipulation and suturing of the maxillary vomer, and scarring of the dentoalveoli post-surgery. Another contributing factor is the intrinsic tissue deficiency. Conclusion: Maxillary hypoplasia is a possible complication following two !ap palatopasty, affecting either anteroposterior, transversal and vertical maxillary growth. This finding needs to be proven especially after the process of growth ceased. It is highly probable that maxillary disruption is higher when the two flap palatoplasty technique leaves lateral areas of denuded bone on the maxillary tuberosity.
Multidisciplinary Approach in Treating Undiagnosed Severe Temporo Mandibular Joint Ankylosis : A Case Report Sandhi, Afriyanti; Pakpahan, Evie Lamtiur; Handayani, Siti; Bangun, Kristaninta
Jurnal Plastik Rekonstruksi Vol. 1 No. 3 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (517.846 KB) | DOI: 10.14228/jpr.v1i3.68

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Background: Temporo Mandibular Joint (TMJ) ankylosis refers to bone or fibrous adhesion of the anatomic joint component and the ensuing loss of their function. The TMJ forms the very cornerstone of craniofacial integrity and hence its ankylosis in growing children adversely affects the growth and development of the jaws and occlusion. Difficulty in mouth opening and mastication, poor oral hygiene and rampant caries pose a severe physical and psychological burden in the tender minds of children. Patient and Method: Bony ankylosis on the right TMJ in a female patient was not diagnosed until the patient reached her early teens, at which the condition was treated by bony fusion release on the right condyle. We managed the patient for further orthognathic surgery (Le Fort I Ostoeotomy and Bilateral Sagittal Split Osteotomy) to correct the skeletal deformity. Result: In collaboration with the Orthodontist for pre-surgery and post-surgery orthodontic treatment, and Physiotherapist for mouth opening and masticatory muscles exercises, a good functional and aesthetic result was achieved. Summary: Multidisciplinary approach in treating severe TMJ ankylosis is mandatory to achieve the optimum results. Awareness among all plastic surgeon and dentist involved in the treatment of craniofacial pathologies in children must be build to allow early diagnosis and treatment.
Maxillary Growth and Speech Outcome in Patient with Cleft Lip and Palate after Two-Stage Palate Repair: A Systematic Review Mulyadi, Mulyadi; Kreshanti, Prasetyanugraheni; Handayani, Siti; Bangun, Kristaninta
Jurnal Plastik Rekonstruksi Vol. 1 No. 4 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (349.437 KB) | DOI: 10.14228/jpr.v1i4.84

Abstract

Background: The management of patients with cleft lip and palate is complex, where the treatment outcome is judged on the balance between aesthetics, speech, and maxillary growth. Up to now, there is no generally accepted treatment protocol. Every center must find the best-suited protocol treatment for their population. Methods: A systematic review through literature search was conducted for English-language studies in PubMed. This search was conducted in September 2011 using EndNote X3 with keywords: Two-stage Palate Repair and Maxillary Growth and Two-stage Palate Repair and Speech Outcome. Both retrospective and prospective studies on maxillary growth and speech outcome in patient with cleft lip and palate after two-stage palate repair published from 2001 to 2012 were included. Result: From the reviewed of 37 articles, only 14 articles fit the inclusions criteria, three articles discussed the outcome of maxillary growth and speech outcome, eight articles only discussed the maxillary growth and the rest of articles only discussed the speech outcome. Conclusion:From this review we found that most of the two-stage palate repair results in better maxillary growth, but only few of them results in good speech outcome. We will perform further study based on this review to discover a new protocol for the management of palate repair in our center.
The Experience of Using Various Modalities For Orbital Floor Fracture Reconstruction Prawoto, Pujisriyani; Handayani, Siti; Bangun, Kristaninta
Jurnal Plastik Rekonstruksi Vol. 1 No. 4 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (556.818 KB) | DOI: 10.14228/jpr.v1i4.87

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Background: Fractures of the orbital floor require surgical intervention in group of patients with cosmetic problems and/or vertical diplopia. The surgical management of these patients provides a great challenge to the surgeon. A variety of implant materials have been used to recreate normal bony orbital dimension or supplement deficient orbital volume which include alloplastic or autogenous materials. The purpose of this case series was to assess the aesthetic and functional outcome of orbital floor reconstruction performed with calvarial bone graft, titanium mesh, absorbable mesh and “Turkish Delight” diced cartilage graft.Patients and Methods: From 2006-2010, we treated eight patients with orbital blowout fracture using various modalities. We used titanium mesh, absorbable mesh, calvarial bone graft and “Turkish delight” diced cartilage. These various modalities were chosen based on clinical examination, patient satisfaction, radiographic investigations and the cost on managing patient.Result: Calvarial bone graft were performed in two patient, “Turkish delight” diced cartilage in one patient, absorbable mesh in one patient, and titanium mesh in four patient. All patients had satisfactory result with adequate volume correction and reduction in vertical diplopia.Summary: All four materials, calvarial graft, titanium mesh, absorbable mesh, and “Turkish delight” diced cartilage graft have the potential to be useful reconstructive materials in orbital floor blowout fractures based on holistic consideration.
Frontoethmoidal Encephalomeningocele Revisited : The Convenience Of Teamwork Approach, A CaseSeries Kusumastuti, Nadia; Handayani, Siti; Hatibie, Mendy; Diah, Enrina; Bangun, Kristaninta
Jurnal Plastik Rekonstruksi Vol. 1 No. 5 (2012): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.979 KB) | DOI: 10.14228/jpr.v1i5.103

Abstract

Background: Frontoethmoidal encephalomeningocele (FEEM) is a congenital defect of the skull which poses many problems to the patient as it results in many craniofacial and neural morbidities. While recently surgical correction of this disease is done in a single-stage procedure, many in Indonesia still perform twostage surgery which bears more risks and is technically difficult to achieve good aesthetic results. This case series intend to assess the feasibility and convenience of teamwork approach between plastic surgeon and neurosurgeon in correcting FEEM in a single-stage operation. Methods:We reviewed 8 patients with FEEM treated in Plastic and Reconstructive Surgery Division, Cipto Mangunkusumo Hospital Jakarta from November 2005 until March 2010. Four of the cases were secondary cases from Neurosurgery Department, and the other 4 cases were treated in single-stage operation, in teamwork with Neurosurgery Department, using the Chula technique. Results of each surgery was assessed using objective parameters, which are Intercanthal Distance (ICD) and Interorbital Distance (IOD); and also subjective parameters which is aesthetic improvement.Result: All of the patients showed significant improvements in ICD and IOD measurements. No complication was found intra and post-operatively. All patients, especially the ones treated with singlestage surgery show good aesthetic results. Conclusion: To achieve goals of defect correction and aesthetically pleasant appearance, single-stage surgery in teamwork with the neurosurgery department seems to be most suitable and convenient.
Co-Authors A., Nur Anindhawati, Nur Aprilia, Mitha Arief Yulianto Arshita W, Baiq Ami Astuti, A Astuti, Sri Lestari Dwi Atmaja, Tessa Miranda Atmodiwirjo, Parintosa Ayuni, Nurani Ira Bangun, Kristaninta Boaz, Grace Budi Setiawan Daimul Hasanah Dedi Riyan Rizaldi Diah, Enrina Djamaloeddin, Chaula Djaprie, Shelly M Djaprie, Shelly Madona Djoenaedi, Intania Dumadi Dupri, Muhammad Demsi Evie Lamtiur Pakpahan Evie Lamtiur, Evie Fahmi, Muhammad Arizal Faisal Faisal Fatimah, Ziadatul Firdaus, Anzar Alfat Fortuna, Forry Fortuna, Fory Grace Wangge, Grace Hakim, Intan Friscilla Halim, Jessica Hapsari, Nathania Pudya Harsono, Anastasia Dessy Hartono Hartono Heri Maria Zulfiati Herman Bakri Imam Santoso Imam Susanto Iman Waskito, Bambang Indania, Alita ISNAENI, NUR Karimah, Aghnini Fitri Khoirunisa, Sonia Kreshanti, Prasetyanugraheni Kreshanti, Prasetyanugrahni Kusumastuti, Nadia Lelawati, Nina Luh Karunia Wahyuni, Luh Karunia Maressa, Reyne Ishka Martina, Nungki Ratna Maulina Rachmasari, Maulina Mendy Hatibie Meruya, Syifa Kamila Miftahul Hasanah, Miftahul Mulyadi Mulyadi Nadya Aqsha Tamarinda Nanik Wijayati Nia Hayati Nindita, Eliza Nobilis, Marchel Nurfitriani, Sarra Pancawati, Julieta Paramita, Noviana Jihan Pargito Pargito Prawoto, Pujisriyani Prayitno, Muh. Rizki Hariz Priharyono, Pandu Widya Putri, Nandita Melati Rayeni, Natasha Ratna Ridwan Abdullah Sani Riski Amalia, Riski Rita Adriani Benya Adriani Rodjani, Ines Hadianesti S Mursiti Salsabila, Auliya Sandhi, Afriyanti Semiaji, Semiaji Septiani, Anisah Simamora, Huntal Siswanto, S.E., M.M., Tito Siti Lestari Soetjipto Soepodo, Fernita Leo Sri Mulyanti Suhendri Suhendri Suparno Susanto, Amila Jeni Susiyanti, Fitri Syamsul Rizal Tania, Vika Taufik Eko Susilo Tiza, Melina Tri Joko Raharjo TRI PRABOWO Trisnaningsih Trisnaningsih Ujang jamaludin Wahyu Tri Sudaryanto Wahyuda, Syefa Maulana Wicaksono, Ilham Bayu Zhahri, Zhahri