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Efektivitas Ekstrak Tempe Kedelai Hitam terhadap Kadar Interleukin 6 pada Tikus Wistar Diabetes Mellitus Tipe 2 Farid, Ulfa Maulida; Romdhani, Ahmad Mundzir; Khalil, Muhammad
Jurnal Jeumpa Vol 10 No 2 (2023): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v10i2.8118

Penelitian ini bertujuan untuk mengetahui efektivitas tempe kedelai hitam terhadap kadar IL-6 pada tikus diabetes mellitus tipe 2. Sebanyak 20 tikus terbagi menjadi 4 kelompok perlakuan yaitu normal (N), diabetes mellitus (K-), glibenclamid (K+), ekstrak tempe kedelai hitam (P1). Tikus jantan Wistar digunakan sebagai model DMT2 yang diobati dengan injeksi diet tinggi lemak (HFD) dan Streptozotosin (STZ) hingga kadar glukosa darah mencapai 200 mg/dl. Percobaan dilakukan dengan memberikan ekstrak tempe kedelai hitam selama 28 hari pada 5 tikus. Serum darah diambil dari jantung dan dilakukan Pemeriksaan kadar interleukin-6 (IL-6) dilakukan dengan metode Enzyme Linked Immunosorbent Assay (ELISA). Analisis data menggunakan uji one way Anova. Hasil penelitian menunjukkan kadar IL-6 kelompok tikus dengan perlakuan pemberian ekstrak tempe kedelai hitam yaitu 150.60 pg/ml yang artinya terdapat pengaruh pemberian ekstrak tempe kedelai hitam terhadap penurunan kadar interleukin 6 (IL-6) pada tikus DMT2.

Urgensi Pengembangan Instrumen Tes Keterampilan Berpikir Komputasional Bertema Biologi bagi Siswa Madrasah Aliyah Ariani, Dina; Ibrahim, Ibrahim; Almukarramah, Almukarramah; Firmansyah, Juli; Khalil, Muhammad
Jurnal Jeumpa Vol 11 No 2 (2024): Jurnal Jeumpa (In Progress)
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v11i2.10828

Upaya yang diperlukan untuk mencapai pendidikan optimal di Era Revolusi Industri 4.0 adalah dengan mengembangkan keterampilan siswa dalam pemecahan masalah yang erat kaitannya dengan kemampuan berpikir komputasional. Jenis penelitian ini adalah deskriptif kualitatif untuk mengetahui urgensi pengembangan instrumen tes keterampilan berpikir komputasional bagi Siswa MAS Darul Ihsan pada mata pelajaran Biologi. Subjek penelitian ini adalah tiga guru Biologi yang ada di MAS Darul Ihsan. Tahapan penelitian meliputi pengambilan data melalui kuesioner, analisis data, dan kesimpulan. Tahapan penelitian meliputi pengumpulan data melalui kuesioner, analisis data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa 58% guru cukup mengetahui tentang keterampilan berpikir komputasional, dan 70% guru kurang mengetahui tentang indikator keterampilan berpikir komputasional. Namun sebanyak 58% guru sudah menerapkan soal dekomposisi, 52% sudah menerapkan soal pengenalan pola, 70% sudah menerapkan soal abstraksi, dan 70% sudah menerapkan soal algoritma. Kesimpulan dari penelitian ini adalah pentingnya keterampilan berpikir komputasional dalam pembelajaran biologi, sehingga perlu dikembangkan instrumen tes untuk mengukur keterampilan tersebut pada siswa di sekolah. Kata Kunci: Berpikir Komputasi, Biologi, Siswa, Madrasah Aliyah.

Implementasi PBL Berbasis Lesson Study untuk meningkatkan Keterampilan Argumentasi Mahasiswa: Implementation of Lesson Study Based PBL to improve Students' Argumentation Skills Khalil, Muhammad; Akbar, Muh. Nur; Ikalor, Allvanialista; Jannah, Raudhatul
Pedagogi Hayati Vol 8 No 1 (2024): Pedagogi Hayati: Jurnal Ilmiah Pendidikan Biologi
Publisher : Department of Biology Education, Faculty of Education and teacher Training, Maritime University of Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/ph.v8i1.6853

Argumentation skills are important to train in learning, so that students have logical reasoning, a clear and rational view of the things being studied. This research aims to examine the implementation of the lesson study-based problem based learning (PBL) model in improving students' argumentation skills. The method used in this research is classroom action research with a quantitative descriptive approach carried out in two cycles. Data was collected using pretest-posttest instruments, argumentation skills observation sheets (Toulmin's argumentation pattern), and lesson study-based PBL syntax implementation observation sheets. The results showed that there was an increase in the implementation of PBL syntax from cycle I (76.9%) to cycle II (92.3%). Likewise, there was a significant increase in students' argumentation skills in each cycle. In the first cycle, there was an increase in the distribution of posttest scores where the percentage of students began to reach levels 3 and 4, while in the second cycle, there was a further increase where the majority of students managed to reach levels 3 and 4 in argumentation skills. The conclusion of this research is that the implementation of lesson study-based PBL can effectively improve students' argumentation skills. It is recommended that further research conduct an in-depth study of the content in each component of argumentation so that a more holistic understanding of students' argumentation skills is obtained.

Jamu Gummies: Innovation for women's health and productivity enhancement of the Sapta Marga village women's association Mayang Murni; Rizky Nafaida; Muhammad Khalil
Community Empowerment Vol 9 No 11 (2024)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12126

This community service program aims to improve women’s reproductive health while supporting the economic productivity of the PKK mothers in Sapta Marga Village, Aceh Tamiang Regency, through the innovation of jamu gummies. The program focuses on transforming rhizomes into practical, tasty, and economically valuable products. The methods implemented include educational sessions on the health benefits of rhizomes and a three-day intensive training covering the production, packaging, and marketing of jamu gummies. Evaluation results indicate a significant improvement in participants' knowledge and skills in rhizome processing, with an average understanding increase of over 80%. The jamu gummies produced are of high quality, meet marketing standards, and are ready to be sold through both digital and conventional marketing strategies taught during the program. The initiative also creates new economic opportunities for PKK mothers without disrupting their household responsibilities.

Urgensi Pengembangan Instrumen Tes Keterampilan Berpikir Komputasional Bertema Biologi bagi Siswa Madrasah Aliyah Ariani, Dina; Ibrahim, Ibrahim; Almukarramah, Almukarramah; Firmansyah, Juli; Khalil, Muhammad
Jurnal Jeumpa Vol 11 No 2 (2024): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v11i2.10831

Pendidikan optimal di Era Revolusi Industri 4.0 memerlukan pengembangan keterampilan pemecahan masalah, yang berkaitan erat dengan kemampuan berpikir komputasional/computational thingking (CT). Penelitian deskriptif kualitatif ini bertujuan untuk mengidentifikasi urgensi pengembangan instrumen tes keterampilan berpikir komputasional bagi siswa Madrasah Aliyah pada mata pelajaran Biologi. Penelitian dilaksanakan pada Juni 2024 dengan subjek guru Biologi di MAS Darul Ihsan. Data dikumpulkan melalui kuesioner dan dianalisis secara deskriptif melalui empat tahapan yaitu analisis pra-lapangan, reduksi data, penyajian data, dan verifikasi data. Hasilnya menunjukkan bahwa sebagian besar guru mengetahui konsep berpikir komputasional (58%), namun pemahaman mereka terhadap indikator spesifik masih terbatas (70%). Meskipun demikian, sebagian besar guru telah menerapkan soal yang mencakup dekomposisi (58%), pengenalan pola (52%), abstraksi (70%), dan algoritma (70%). Kesimpulannya, diperlukan upaya lebih lanjut untuk mengembangkan instrumen tes yang efektif dan akurat dalam mengukur keterampilan berpikir komputasional siswa dalam pembelajaran Biologi.

Pengembangan AR Book Bioinformatika: Visualisasi In Silico Potensi Tanaman Herbal Lokal Khalil, Muhammad
Jurnal Jeumpa Vol 12 No 1 (2025): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jj.v12i1.11629

Bioinformatika merupakan bidang penting dalam pendidikan biologi modern, namun penyampaian materinya sering menghadapi tantangan karena sifat konsep yang abstrak dan kompleks. Untuk mengatasi hal tersebut, penelitian ini bertujuan mengembangkan media pembelajaran berbasis augmented reality (AR) dalam bentuk AR Book pada materi Kajian Potensi Tanaman Herbal secara In Silico yang digunakan dalam mata kuliah Bioinformatika di Program Studi Pendidikan Biologi FKIP Universitas Samudra. Penelitian ini menggunakan model pengembangan ADDIE yang dibatasi pada tahap analisis, desain, dan pengembangan. Hasil analisis kebutuhan menunjukkan perlunya media interaktif berbasis digital. Media dikembangkan dalam bentuk buku dengan marker visual yang terintegrasi dengan aplikasi AR berbasis Android. Hasil validasi menunjukkan tingkat kelayakan oleh ahli materi sebesar 87% dan ahli media sebesar 82%, keduanya dalam kategori sangat layak. Kesimpulannya, media ini efektif mendukung visualisasi konsep abstrak dalam pembelajaran bioinformatika dan berpotensi meningkatkan pemahaman mahasiswa melalui pengalaman belajar yang interaktif dan kontekstual.

Detection and In Silico Study of Neochlorogenic Acid from Rhizophora apiculata Stem Bark Extract as HBV Replication Inhibitors Muhammad Khalil; Yonadiah Dwitya
Jurnal Penelitian Pendidikan IPA Vol 9 No 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.5144

This study aims to detect and characterize the presence of neochlorogenic acid in Rhizophora apiculata stem bark extract and to examine its potential as an inhibitor of Hepatitis B virus (HBV) replication with in silico approach. This explorative descriptive study used liquid chromatography-mass spectrometry (LC-MS/MS) analysis to detect the content of neochlorogenic acid, and an in silico study through molecular docking analysis using the blind docking technique to test its potential to inhibit HBV replication. LCMS/MS results showed that the neochlorogenic acid was present in R. apiculata stem bark extract which was detected with a peak at 3.94 retention time, and fragment ion with a m/z value of 355.1029. The docking analysis results showed that neochlorogenic acid forms a binding site that is relatively similar to the reference ligand to the HBV capsid protein, involving amino acid residues PHE 23, PRO 25, PHE 110, TYR 118, TRP 102, ILE 139, LEU 140, and SER 141, with binding affinity score -6.3 kcal/mol. Therefore, based on the results of this study, it can be concluded that neochlorogenic acid derived from stem bark extract of R. apiculata has the potential to be used as an alternative treatment for hepatitis B virus infection.Â

Smart Teacher di Era Digital: Penguatan Kompetensi TPACK pada Guru JSDI Aceh Timur Muhammad Khalil; Hasby Hasby; Okhaifi Prasetyo
Jurnal Surya Masyarakat Vol 7, No 1 (2024): November 2024
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.7.1.2024.72-80

This community service activity aims to increase TPACK (Technological Pedagogical Content Knowledge) competency among teachers who are members of the Indonesian Digital School Network (JSDI) in East Aceh. Through a series of stages that include planning, implementing education and workshops, as well as evaluation, the results show a significant increase in teachers' understanding and skills regarding the TPACK concept. Teachers are able to integrate technology in learning effectively, supporting the implementation of the Independent Curriculum. Evaluation shows an increase in the average score from pre-test to post-test by 41.6%. Collaboration between the service team from Samudra University and JSDI East Aceh partners strengthens the effectiveness of this program. Despite facing challenges such as technological skills gaps and limited facilities, the solution implemented is in the form of individual assistance and the provision of simple but effective technological alternatives. Sustainability of this program is sought through regular mentoring and additional training. This activity emphasizes the importance of a needs-based approach, ongoing support, and effective collaboration to improve the quality of education. With strong commitment from all parties, it is hoped that the Smart Teacher concept can be realized, creating a learning environment that is more innovative, inclusive and adaptive to changing times.

Smart Teacher di Era Digital: Penguatan Kompetensi TPACK pada Guru JSDI Aceh Timur Muhammad Khalil; Hasby Hasby; Okhaifi Prasetyo
Jurnal Surya Masyarakat Vol 7, No 1 (2024): November 2024
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jsm.7.1.2024.72-80

This community service activity aims to increase TPACK (Technological Pedagogical Content Knowledge) competency among teachers who are members of the Indonesian Digital School Network (JSDI) in East Aceh. Through a series of stages that include planning, implementing education and workshops, as well as evaluation, the results show a significant increase in teachers' understanding and skills regarding the TPACK concept. Teachers are able to integrate technology in learning effectively, supporting the implementation of the Independent Curriculum. Evaluation shows an increase in the average score from pre-test to post-test by 41.6%. Collaboration between the service team from Samudra University and JSDI East Aceh partners strengthens the effectiveness of this program. Despite facing challenges such as technological skills gaps and limited facilities, the solution implemented is in the form of individual assistance and the provision of simple but effective technological alternatives. Sustainability of this program is sought through regular mentoring and additional training. This activity emphasizes the importance of a needs-based approach, ongoing support, and effective collaboration to improve the quality of education. With strong commitment from all parties, it is hoped that the Smart Teacher concept can be realized, creating a learning environment that is more innovative, inclusive and adaptive to changing times.

EDUCATION AND WORKSHOP ON INTEGRATING DEEP LEARNING AND GAME-BASED LEARNING IN DEVELOPING DIGITAL EDUCATION CARDS FOR HIGH SCHOOL TEACHERS IN EAST ACEH Okhaifi Prasetyo; Hasby Hasby; Muhammad Khalil
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 4 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i4.2025.559-570

High school teachers in East Aceh face the challenge of limited skills in integrating technology, deep learning approaches, and game-based learning (GBL) strategies into teaching media. This condition results in learning that tends to remain conventional and less contextual to 21st-century needs. This community service activity aims to increase teacher capacity through education and workshops in developing digital educational cards based on local values using the Technological Pedagogical Content Knowledge (TPACK) framework. The activity was carried out at SMAN Unggul East Aceh for three days and involved 30 teachers from various subjects. The methods used included providing conceptual material, direct practice, collaborative mentoring, and evaluation through pretests and posttests, observations, and satisfaction questionnaires. All data were analyzed descriptively to describe improvements in participant knowledge, skills, and satisfaction. The results showed an increase in teacher understanding based on the average posttest score, which increased from 5.41 to 8.65, and the participant satisfaction level reached 4.75 on a scale of 5. The concrete product, in the form of interactive digital educational cards, produced by teachers demonstrated the ability to integrate local values into learning. This program is considered successful in creating a participatory, reflective, and creative learning atmosphere, and is recommended to be continued through ongoing mentoring and the formation of a teacher practice community.

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