Andon Hestiantoro
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta

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Endometriosis Toraks di Diafragma Dextra dengan Manifestasi Nyeri Dada dan Pneumotoraks Dharmawan, Tommy; Chandra, Tania Maharani; Hestiantoro, Andon; Harahap, Agnes Stephanie
Majalah Kedokteran Indonesia Vol 73 No 4 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.4-2023-1169

Abstract

Introduction: Thoracic endometriosis is a rare disease but could lead to morbidity and mortality. Early detection with prompt anamnesis and supporting examination may direct the best therapy and also increase the prognosis of patient.Case report: On this case report, we presented a female patient with right chest pain and shortness of breath on menstruation time.Discussion: From chest X-ray we found right pneumothorax and it led to chest tube placement on the right chest. The anamnesis supported the diagnosis of thoracic endometriosis and furthermore from CT scan we found lesion on the right diaphragm. So, we proceeded with minimal invasive surgery (video assisted thoracoscopic surgery (VATS)). Pathology anatomy examination revealed a true endometriosis lesion.Conclusion: The operation went uneventful and then post operative we gave gonadotropin releasing hormone analog.
Exploring the Potential of Lifestyle and Dietary Intervention to Improve In Vitro Fertilization Outcomes in Overweight and Obese Women: Systematic Review and Meta-Analysis Abdullah, Muhammad Raoul Taufiq; Hestiantoro, Andon
Jurnal Ilmu Kesehatan Masyarakat Vol. 14 No. 06 (2025): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v14i06.4346

Abstract

Lifestyle and dietary interventions have been proposed to improve in vitro fertilization (IVF) outcomes in women with overweight and obesity, conditions known to reduce reproductive success. This systematic review followed PRISMA guidelines and searched PubMed, MEDLINE, and Scopus up to July 2025. Four randomized controlled trials involving 433 participants met inclusion criteria. A fixed-effects meta-analysis showed that weight loss interventions significantly increased clinical pregnancy rates (OR 1.55; 95% CI 1.03–2.35; p=0.04), with low heterogeneity (I²=32%). The strongest effect was reported in Sim 2014 (OR 5.07; 95% CI 1.21–21.28). Improvement in IVF outcomes is likely mediated through enhanced insulin sensitivity, reduced inflammation, and better hormonal regulation. Although both obesity and advanced maternal age reduce fertility, obesity has a greater impact on IVF success in younger women; therefore, weight reduction may be particularly beneficial for women under 35–38 years. In contrast, delaying treatment for weight loss may disadvantage older women due to age-related fertility decline. Overall, lifestyle-based weight loss significantly improves IVF outcomes and should be integrated into treatment planning for overweight and obese patients.