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Journal : Current Biochemistry

Antibacterial Activity of Lemongrass (Cymbopogon nardus) Ethanolic Extract Waras Nurcholis; Mira Takene; Ratna Puspita; Lisnawati Tumanggor; Eka Nurul Qomaliyah; Muhammad Maftuchin Sholeh
Current Biochemistry Vol. 6 No. 2 (2019)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.6.2.4

Abstract

Infectious diseases are a disease caused by bacteria such as Escherichia coli and Staphylococcus aureus. One way to overcome the disease by using antibiotics. However, wise use can lead to antibiotic resistance, so many bacteria are resistant to antibiotics. Therefore it is necessary to search the natural compounds as antibacterials, one of them by using lemongrass (Cymbopogon nardus). This study aims to determine the effectiveness of leaf extracts, stems, and roots lemongrass as antibacterial. The method used in this research is the disc method. Bacteria used are E. coli and S. aureus. The results show extracts of roots, stems, and leaf has activity against S. aureus, while E. coli shows no activity as antibacterial, it can be possible because of the different properties of the bacteria. Keywords: anti-bacteria, lemongrass, Escherichia coli, Staphylococcus aureus
Phytochemical Screening, Total Flavonoids and Antioxidants of Kalanchoe Pinnata Linn. Leaves Qomaliyah, Eka Nurul; Indriani, Nurul; Rohma, Atika; Islamiyati, Ricka
Current Biochemistry Vol. 10 No. 1 (2023)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.10.1.1

Abstract

Kalanchoe pinnata Linn. or in Indonesia known as cocor bebek, this plants grow well in temperate and tropical regions. Cocor bebek is used to treat several diseases including skin diseases, wound healing, kidney stones, gallstones, diabetes. The pharmacological activities of cocor bebek leaves have been reported as anti-inflammatory, anti-oxidant and anti-microbial. The objective of this study is to determine the metabolite content of cocor bebek leaves, total flavonoid levels and antioxidant activity. Observations of secondary metabolites of cocor bebek leaves were carried out through qualitative secondary metabolite screening, while total flavonoid levels were carried out quantitatively UV-VIS with quercetin as a comparison, atioksidan activity through DPPH molecular inhibition testing. The results of this study indicate that cocor bebek leaves contain alkaloids, flavonoids, saponins, triterpenoids, tannins and phenols. 200gr of cocor bebek leaves obtained % yield extract is 14.63%. The total favonoid content obtained was 8.77% of quercetin, while the antioxidant inhibition of DPPH molecules obtained IC50 of 97.42 ppm.
Co-Authors A'yuni, Shahira Qistan Abraham Tiandno Witjaksono Afandi, Frendy Ahmad Agus Setyono Ainul Yaqin Aji Kresnapati, Bagus Arifin, Achmad Saiful Asyaun Niqris, Adelliana Aulia Azahra, Rahmania Ayu, Fatma Aisyah Baiq Yulia Hasni Pratiwi Bambang Pontjo Priosoeryanto Chairani Fatimah, Nina Damayanti, Lisa Kurnia Anggraeni Deny Setiawan Dewi, Kadek Risa Rivana Dian Nugraheni Fardani, Indra Fardhani, Indra Fiel’ardh, Khalifatulloh Fitrah, Aura Relia Habiddin Hanandya Rahma Dinda Destriani Hasim - Hasim Hasim Hasim Hasim I Gusti Nyoman Hari Satwika I Made Kawi Widana I Nyoman loka Islamiyati, Ricka Jibril Maulana Kresnapati, I Nyoman Bagus Aji Kurniawati, Nika Fitri Lisnawati Tumanggor Maudina, Rahma Ursula Maysara, Maysara Mira Takene Moh Asroriy Nuris Muchsin, Lalu Busyairi Mudawil Qulub Muhamad Azwar Muhammad Eka Putra Ramandha Muhammad Maftuchin Sholeh Muhsin, Lalu Busyairi Mukti, Nuril Chasanah Murti, Aisyah Andhina Nadia, Intan Naila Zulfa Nina Chairani Fatimah Nisa, Hafidzah Ra'iyatun Nurul Indriani Nyoman Bagus Aji K Prabowo, Himawan Ganjar Praptawati, Atika Ramadhani, Muhammad Wisda Pradja Ratna Puspita Relia Fitrah, Aura Rini Anggi Arista Riyanto, Obaja Eden Santosa Rohma, Atika Rosita Assyifa Purba Royana, Dhita Fitri Santosa, Khalis Nadhira Setyoningrum, Nadia Shinta Permata Sari Shofi, Fifi Maziyatus Sofya, Sri Winarni Sri Winarni Sofya Sri Winarni Sofya Sugiyanto - suhartatik suhartatik Sukib Sukib Surya Pangidoan Nasution Syamsuddi, Imam Syamsuddin, Imam Umi Fitriyati Waras Nurcholis Widowati, Tamara Rahma Winarni, Nasrunniati Dyahayu Anggi Yasin, Ikrar Riyas Mutawaqil Yayuk Mulyati