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All Journal Jurnal Kesehatan Andalas Paediatrica Indonesiana Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI)

Rismawati Yaswir

Bagian Patologi Klinik Dan Kedokteran Laboratorium, Fakultas Kedokteran, Universitas Andalas, Padang

Author-ID : 2836520

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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The Correlation Between Adiponectin Levels With C-Reactive Protein in Adult Obese Non-Diabetic Among Staffs of DR. M. Djamil Hospital Padang Dian Eka Putri; Rismawati Yaswir; Desywar Desywar; Efrida Efrida
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2021): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v15i1.2719

The adiponectin and C-reactive protein (CRP) are markers of chronic low-grade inflammation related to obesity. This study aims to determine a correlation between adiponectin level and CRP level in adult obese individuals. This study was analyzed with a cross-sectional design of 55 subjects at Dr. M Jamil Central Hospital Padang from January to September 2019. The subjects included were type 1 obese (25≤BMI≤29.9 kg/m2) and type 2 obese (BMI 30.0 kg/m2). Enzyme-linked immunoassay (ELISA) was used to measure adiponectin and High Sensitivity C-Reactive Protein (Hs-CRP) levels. Univariate statistical analysis is processed and presented in distribution, frequency, mean (standard deviation), median (minimum-maximum value). Bivariate data were analyzed using the Pearson correlation test, significant if p<0.05. The study consists of 16 males and 39 females. The mean age was 35 years old (the range 23 to 57 years old), the mean BMI was 30.8 (4.5) kg/m2. This study consists of 28 subjects, type 1 obese and 27 types II obese. The mean adiponectin level in type 2 obese is lower than in type 2 obese groups. The mean CRP levels are high in all populations. Pearson ln-adiponectin and CRP correlation test in the entire population: r =-0.105 (p=0.444).

PERBEDAAN INSIDENSI DIABETES MELITUS TIPE 2 DAN HBA1C PADA POPULASI TERPAPAR-TIDAK TERPAPAR EMISI PABRIK SEMEN PADANG Prima Adelin; Rismawati Yaswir; Zelly Dia Rofinda; Rizanda Machmud; Husna Yetti
Health and Medical Journal Vol 3, No 2 (2021): HEME July 2021
Publisher : Universitas Baiturrahmah

Background: Cement factory emission disrupt blood glucose control through insulin resistance mechanism, thus increasing incidence of type 2 diabetes mellitus (DM type 2). Aim: Aim of this study is to determine incidence’s differences of DM type 2 and mean HbA1c patients with DM type 2 within population exposed and unexposed cement Padang factory emission. Method: This was a cross sectional analytic study with cluster sampling that conducted on June-December 2015 with 129 and 125 participant from exposed and unexposed areas. Age of participants are 20-79 years old. Incidence is total new cases per total sample in exposed or unexposed area. HbA1c were measured with immunoturbidimetry method. Data were analyzed by chi-squared test to asses differences of two proportions and t test to asses differences of two averages. Results: The incidence DM type 2 are 3,9% and 7,2% respectively in exposed and unexposed areas, without significant difference (p>0,05). The mean HbA1c patients DM type 2 are 10,0(2,4)% and 8,8(1,6)% in exposed and unexposed areas, without significant difference (p>0,05). Conclusions: There were no significant differences incidence of DM type 2 and mean HbA1c patients DM type 2 in the populations exposed and unexposed cement Padang factory emission. Cohort studies is required to see the effects of cement factory emission

Perbedaan Kadar Non High Density Lipoprotein Cholesterol pada Mahasiswa Penyandang Obes dan Non Obes Sri Vanny Suhirman; Efrida Efrida; Rismawati Yaswir
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 2 (2021): Juni 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

ABSTRACT THE DIFFERENCE OF NON HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVELS IN OBESE AND NON OBESE STUDENT By Sri Vanny Suhirman Non High Density Lipoprotein Cholesterol was calculated as total cholesterol levels minus HDL levels. Non HDL-C levels can be used as a predictor of cardiovascular disease risk. Non HDL-C levels tend to increase in obese people. This research aims to determine the differences of non HDL-C levels in obese and non obese students. This research was an observational analytic study with a cross sectional design. This research was conducted at the Central Laboratory of Dr. M. Djamil Hospital Padang from July 2020 to February 2021. The sample was 60 students at Faculty of Medicine, Andalas University, consists of 30 obese students and 30 non obese students. Statistical analysis used the independent T-test. The significant test results if the p value <0.05. The results showed that the mean age of the subjects was 20.32±1.05 years. The mean BMI in obese student was 32.53 ± 4.13 kg/m2 and the mean BMI in non obese student was 21.11 ± 1.85 kg/m2. The mean non HDL-C level in the obese student was 131.43 ± 34.70 mg/dL and the mean non HDL-C level in non obese student was 123.93 ± 35.55 mg/dL. Bivariate analysis found that there was no significant difference between the mean non-HDL C levels in the obese student and non obese student (p = 0.412). The conclusion in this research is the mean non HDL-C levels in the obese and non obese student is not different. Keywords: Body mass index, Non High Density Lipoprotein Cholesterol, Obesity

Gambaran Castelli’s Risk Index-2 pada Pasien Sindrom Koroner Akut di RSUP Dr. M. Djamil Padang Huriyah Fauzani; Rismawati Yaswir; Rosfita Rasyid
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 4 (2021): Desember 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v2i4.254

Latar belakang: Sindrom koroner akut termasuk penyakit jantung koroner yang merupakan masalah kesehatan dengan angka morbiditas dan mortalitas tinggi di dunia. Dislipidemia aterogenik adalah salah satu faktor risiko kejadian sindrom koroner akut, yaitu tingginya kolesterol low density lipoprotein dibanding kolesterol high density lipoprotein, serta peningkatan kadar trigliserida. Castelli’s risk index-2 adalah rasio kadar kolesterol low density lipoprotein dan kolesterol high density lipoprotein, salah satu parameter lipid yang menjadi penanda risiko kejadian sindrom koroner akut. Tujuan: Mengetahui gambaran Castelli’s risk index-2 pada pasien sindrom koroner akut di Rumah Sakit Dr. M. Djamil Padang tahun 2017-2018. Metode: Penelitian dilaksanakan di Laboratorium Patologi Klinik RSUP Dr. M. Djamil Padang pada September 2017-Oktober 2020. Hasil penelitian diperoleh dari data sekunder rekam medis, pengambilan data diambil secara total sampling. Sampel yang memenuhi kriteria inklusi dan eksklusi dari penelitian ini berjumlah 70 pasien dengan diagnosis sindrom koroner akut di RSUP Dr. M. Djamil Padang periode September 2017-September 2018. Hasil: Penelitian menunjukkan pasien sindrom koroner akut di RSUP Dr. M. Djamil Padang tahun 2017-2018 terbanyak pada laki-laki (71,43%), kelompok umur 56-65 tahun (42,86%), rerata kadar kolesterol LDL 108,86 mg/dL, dan rerata kolesterol HDL 35,71 mg/dL. Rerata Castelli’s risk index-2 pada keseluruhan subjek sebesar 3,27. Kesimpulan: Penderita sindrom koroner akut memiliki rerata kolesterol LDL lebih tinggi dari nilai optimal dengan rerata kolesterol HDL lebih rendah dari nilai optimal sehingga menyebabkan peningkatan Castelli’s risk index-2.

Korelasi Kadar Vitamin D dengan Indeks Aterogenik Plasma pada Mahasiswa Penyandang Obesitas M. Ikhlasul Amal Eel Taslim; Zelly Dia Rofinda; Rismawati Yaswir
Jurnal Ilmu Kesehatan Indonesia Vol 2 No 4 (2021): Desember 2021
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v2i4.521

Latar Belakang: Defisiensi vitamin D telah menjadi masalah kesehatan dunia dan berkembang pesat selama beberapa tahun terakhir ini. Defisiensi vitamin D merupakan salah satu faktor risiko penyakit kardiovaskular. Indeks aterogenik plasma yang dirumuskan sebagai log10(TG/HDL) merupakan penanda aterogenesitas untuk memperkirakan risiko penyakit kardiovaskular. Defisiensi vitamin D dan nilai indeks aterogenik plasma yang tinggi sering ditemukan pada penyandang obes. Objektif: Penelitian ini bertujuan untuk mengetahui korelasi antara kadar vitamin D dengan indeks aterogenik plasma pada mahasiswa penyandang obes. Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional yang dilakukan di Fakultas Kedokteran Universitas Andalas dan Laboratorium Sentral RSUP Dr. M. Djamil Padang dari bulan Agustus 2020 hingga April 2021. Subjek penelitian ini adalah 30 mahasiswa angkatan 2017-2018 penyandang obes di Fakultas Kedokteran Universitas Andalas, yang terdiri dari 16 orang laki-laki dan 14 orang perempuan. Hasil: Hasil penelitian didapatkan rerata umur subjek 19,57±0,86 tahun dan rerata IMT 32,53±4,13 kg/m2. Rerata kadar vitamin D subjek 13,90±4,10 ng/mL dan rerata indeks aterogenik plasma subjek -0,025±0,237. Analisis bivariat didapatkan korelasi negatif sangat lemah dan tidak bermakna antara kadar vitamin D dengan indeks aterogenik plasma (r= -0,129; p= 0,498). Kesimpulan: Tidak terdapat korelasi yang bermakna antara kadar vitamin D dengan indeks aterogenik plasma pada mahasiswa penyandang obes.

Korelasi Indeks Adipositas Viseral dengan Vitamin D pada Penyandang Obesitas Yessi Yestiani; Rismawati Yaswir; Syofiati Syofiati; Efrida Efrida
Majalah Kedokteran Andalas Vol 46, No 2 (2023): Online April 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i2.p295-300.2023

Tujuan Penelitian: Mengetahui hubungan antara IAV dengan vitamin D pada penyandang obes. Metode: Penelitian analitik dengan rancang potong lintang dilakukuan terhadap 50 penyandang obes di RSUP Dr. M. Djamil Padang Januari 2021 hingga Oktober 2021. Pemeriksaan kadar vitamin D menggunakan metode CMIA. Pemeriksaan kadar trigliserida (TG) dan kolesterol high density lipoprotein (K-HDL) puasa menggunakan metode enzimatik. Nilai IAV dikalkulasi dengan rumus matematika berdasarkan indeks antropometri berupa indeks massa tubuh, lingkar pinggang, TG dan K-HDL. Data dianalisis dengan uji korelasi Spearman, bermakna jika p <0,05, selanjutnya dilakukan analisis regresi linear bivariat. Hasil: Rerata usia subjek penelitian 28(18-60) tahun. Rerata kadar vitamin D perempuan 12,8(6,8–28,7) ng/mL. Rerata kadar vitamin D laki-laki 17,6(9,8-26,3)ng/mL. Rerata nilai IAV perempuan 3,06(1,28-9,12). Rerata nilai IAV laki-laki adalah 2,06(0,5-4,21). Uji statistik menunjukkan korelasi tidak bermakna IAV dan vitamin D pada perempuan (r = -0,110 p= 0,599) dan pada laki-laki(r = 0,129 p= 0,537). Pembahasan: Nilai rerata IAV perempuan lebih tinggi dibandingkan laki-laki. Rerata kadar vitamin D laki-laki lebih tinggi dari perempuan. Keterbatasan penelitian ini jumlah sampel sedikit. Simpulan: Nilai IAV tidak berkorelasi dengan vitamin D pada penyandang obes. Diperlukan penelitian lebih lanjut mengenai hubungan IAV dengan defisiensi vitamin D pada penyandang obes.Kata kunci: IAV, vitamin D, obes.

Korelasi Rasio Trigliserida/High Density Lipoprotein dengan HOMA-IR pada Penyandang Obesitas Raisa Putri Secioria; Rismawati Yaswir; Desywar Desywar; Efrida Efrida
Majalah Kedokteran Andalas Vol 46, No 2 (2023): Online April 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i2.p260-266.2023

Tujuan: Mengetahui korelasi rasio trigliserida (TG)/high density lipoprotein (HDL) dengan homeostasis model assessment of insulin resistance (HOMA-IR) pada penyandang obesitas.Metode: Penelitian analitik dengan rancangan potong lintang dilakukan terhadap 65 penyandang obesitas (indeks massa tubuh (IMT) ≥ 25,0 kg/m2) dewasa non-diabetes di RSUP Dr. M. Djamil Padang sejak Januari hingga September 2022. Pemeriksaan TG menggunakan metode glycerol phosphate oxidase, HDL dengan kolorimetri enzimatik homogen, glukosa dengan heksokinase, dan insulin dengan chemiluminescent microparticle immunoassay. Nilai HOMA-IR dihitung menggunakan kadar glukosa darah puasa (mg/dL) x insulin puasa (µU/mL)/405. Data dianalisis dengan uji korelasi Pearson, bermakna jika p<0,05.Hasil: Subjek penelitian sebagian besar perempuan (60,0%). Median umur 28 tahun dan rerata IMT 31,9 kg/m2. Median kadar TG 117 mg/dL, HDL 42 mg/dL, glukosa darah puasa 83 mg/dL, insulin puasa 10,6 µU/mL, rasio TG/HDL 2,9, dan HOMA-IR 2,3. Uji korelasi menunjukkan rasio TG/HDL berkorelasi dengan HOMA-IR (r=0,290; p=0,019).Simpulan: Terdapat korelasi positif lemah antara rasio TG/HDL dengan HOMA-IR pada penyandang obesitas. Penelitian lebih lanjut diperlukan dengan merekrut subjek berdasarkan persentase lemak tubuh, derajat dan lama obesitas, aktifitas fisik, dan jenis kelamin.

CORRELATION OF SERUM HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND HOMOCYSTEINE LEVEL IN PATIENT WITH ACUTE MYOCARDIAL INFARCTION Yayie Dwina Putri; Tuty Prihandani; Lillah Lillah; Rismawati Yaswir
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 25 No. 1 (2018)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v25i1.1515

Acute Myocardial Infarction (AMI), one of the primary manifestation of coronary heart disease, is a significat cause of death worldwide. Hyperhomocysteinemia, a risk factor for cardiovascular disease, is caused by nutritional or genetic disturbances in homocysteine metabolism. The role of hyperhomocysteinemia in altered lipid metabolism presumed holds the key to an increased risk of cardiovascular disease. Hyperhomocysteinemia causes the reduction of serum High-Density Lipoprotein (HDL) cholesterol level by inhibiting hepatic synthesis of apo-A1 (significant apolipoprotein HDL). The aim of this study was to know the correlation between hyperhomocysteinemia and decreased HDL cholesterol levels for the management of cardiovascular disease risk factors. This research was an analytical study with cross-sectional design in 40 patients AMI who meet the inclusion and exclusion criteria and conduct blood test at the Central Laboratory of Hospital Dr. M. Djamil Padang and Biomedical Laboratory Faculty of Medicine Andalas University. The study was conducted in May 2016-Agustus 2017. Homocysteine level was measured by ELISA method. High-Density Lipoprotein level was performed by enzymatic colorimetric method. Data were analyzed by Spearman's correlation test. Research subjects were 40 people with male gender 30 (75%) and female 10 (25%), mean age 61.08 (11.09) year. The mean level of HDL cholesterol in patients with AMI is 41.93 ± 13.12 mg/dL. The mean level of homocysteine in patients with AMI is 25.36 ± 22.2 µmol/L. Spearman's correlation test showed a strong correlation between the levels of homocysteine and HDL cholesterol with r=-0.603 and p<0.01.

Nilai ASTO Pasien Tonsilitis Kronis Pre dan Pasca Tonsiloadenoidektomi Dengan Riwayat Endokarditis Infeksi Syahri Gunawan; Novialdi Novialdi; Rismawati Yaswir; Didik Hariyanto; Aulia Rahman
Majalah Kedokteran Andalas Vol 46, No 6 (2023): Online Oktober
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i6.p1118-1127.2023

Tonsilitis merupakan salah satu manifestasi paling sering dari infeksi saluran nafas atas. Pada pasien dengan tonsilitis kronis terdapat kecenderungan peningkatan titer Anti Streptolisin O, sebuah antibodi terhadap antigen Streptolisin O yang dihasilkan oleh bakteri Streptokokus β Hemolitikus grup A. Bakteri yang juga diketahui menjadi agen penyebab pada penyakit jantung infeksi. Tujuan: Mengetahui dan menginterpretasikan nilai ASTO pasien tonsilitis pre dan paska tonsiloadenoidektomi dengan riwayat endokarditis infeksi Laporan Kasus: Seorang anak perempuan 15 tahun dilaporkan dengan tonsilitis kronis dan post infective endocarditis definite. Pada pasien dilakukan pengukuran titer ASTO sebelum dan sesudah tindakan tonsiloadenoidektomi. Setelah dilakukan tonsiloadenoidektomi didapatkan bahwa titer ASTO menjadi negatif. Kesimpulan: Tonsiloadenoidektomi pada pasien dengan tonsilitis kronis dapat menurunkan kadar ASTO dan reaktivasinya sehingga dapat menghindari resiko terjadinya komplikasi yang berhubungan dengan Streptokokus β Hemolitikus grup A

Correlation of High Sensitive Troponin I (hsTnI) with Platelet Distribution Width (PDW) in Acute Myocardial Infarction Patients Aisyah Mayang Wulan; Rismawati Yaswir; Desywar
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1038

Background: Acute myocardial infarction (AMI) occurs due to rupture of atherosclerotic plaque which triggers platelet activation and aggregation to form a thrombus. Several studies have examined the relationship between PDW and AMI, but there is no specific correlation with hsTnI as the most sensitive and specific cardiac biomarker for AMI. This study aims to analyze the correlation between hsTnI levels and PDW values in AMI patients. Methods: Cross-sectional study of 60 AMI patients in the emergency room of Dr. M. Djamil General Hospital Padang from April to August 2022. Research subjects who met the inclusion and exclusion criteria underwent hsTnI and PDW examinations. The correlation of hsTnI with PDW was analyzed using the Spearman correlation test. Correlation is declared significant if the p-value is <0.05. Results: The research sample consisted of 48 men (80%) and 12 women (20%). The average age is 60.67 (10.73) years with an age range of 33-82 years. The mean hsTnI level was 2,606.10 (2,404.79) ng/Land the mean PDW value was 10.97 (2.26) fL. There was a strong and significant positive correlation between hsTnI and PDW in AMI patients (r = 0.618, p = 0.000). Conclusion: There is a correlation between hsTnI levels and PDW values at AMI.

Co-Authors Adelin, Prima Afrida Maiyesi Aisyah Mayang Wulan Akmal M Hanif Ardho Mahamada Arina Widya Murni Aulia Rahman Aulia Rahman Bahana Sasmita Bakma, Isphandra Bayu Rahmadin Cici Julia Sri Dewi Debie Anggraini Deswita Sari Desywar Desywar Desywar Desywar Desywar Desywar Desywar Desywar Desywar Desywar Desywar Desywar Desywar, Desywar Dewi Oktavia Dia Rofinda, Zelly Dia Dian Eka Putri Didik Hariyanto Didik Hariyanto Donaliazarti Donaliazarti Dwi Yulia Efrida Efrida Efrida Efrida Efrida, Efrida Eka Agustia Rini Eka Musmita Sabebegen Ellyza Nasrul Elsi Kelana Eugeny Alia Fadhillah Al Hijjah Farida Isroani Fitria, Syarifah Tridani Gunawan, Syahri Hanifah Maani Helma Helma Huriyah Fauzani Husna Yetti Husni Husni Husni Husni Ilhamifithri Ilhamifithri Ima Septia Indra Ihsan Ira Ferawati Irza Wahid Isphandra Bakma Kartika Aulia Sari Kurniawan Lillah Lillah Lillah Lillah Lillah Lillah Lillah Lillah M. Ikhlasul Amal Eel Taslim Meiti Frida Mira Purwinanty Muthia Rendra Nafiandi Nafiandi Noer Hafni Nora Harminarti Novialdi . Nur Afrianin Syah Prihandani, Tuty Putri Mira Magistri Raisa Putri Secioria Reni Lenggogeni Ridha Amaliah Rizanda Machmud Rosfita Rasyid Sabebegen, Eka Musmita Sari, Kartika Aulia Sri Nurul Huda Sri Vanny Suhirman Syahri Gunawan Syarifah Tridani Fitria Syofiati Syofiati Syofiati Syofiati Tuti Asryani Tuty Prihandani Tuty Prihandani Tuty Prihandani Wardhy Arief Hidayat Yashinta Octavian Gita Setyanda Yayie Dwina Putri Yerizal Karani Yessi Yestiani Yoshie Anto Chicamy Yustini Alioes Zelly Dia Rofinda

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