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All Journal JBIO: jurnal biosains (the journal of biosciences) Prosiding Seminar Biologi Elkawnie Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Jurnal Penelitian Kesehatan Suara Forikes Jurnal Penelitian Pendidikan IPA (JPPIPA) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Buletin Farmatera Indonesian Journal of Medicine IJOEP : International Journal of Ecophysiology Bioscientist : Jurnal Ilmiah Biologi Archives of The Medicine and Case Reports Prosiding Seminar Nasional Biologi, Teknologi dan Kependidikan (Biotik)
Syafruddin Ilyas
Department Of Biology, Faculty Of Mathematics And Natural Sciences, Universitas Sumatera Utara
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Buletin Farmatera

 1 
EFFECTS OF METHANOL EXTRACT AND N-HEXANE EXTRACT OF PAPAYA LEAVES (CARICA PAPAYA L) ON TOTAL AND DIFFERENTIAL WHITE BLOOD CELL COUNTS IN MALE WISTAR RATS AFTER CARRAGEENAN INDUCTION Okto P.E Marpaung; Datten Bangun; Syafruddin Ilyas
Buletin Farmatera Vol 4, No 2 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (730.05 KB) | DOI: 10.30596/bf.v4i2.3016

Abstract

As one of the countries producing medicinal plants, Indonesia has the potential to develop medicinal plants in the future. The anti-inflammatory effects of methanol and n-hexane extract from papaya leaves were seen in this study using a pretest-posttest control group design using 36 male adult Wistar rats divided into 6 groups. All rats received 1 week acclimatization, then blood specimens were taken from the tail, after which they were treated, and intraplantar injections were carried out with 1% carrageenan solution as much as 0.1 ml. Then retrieval of blood specimens from rats' tails at 3 hours and 6 hours afterwards. Then an examination of the number and type of leukocytes was performed on all blood specimens obtained. It was found that the number of male Wistar rat leukocytes after getting methanol extract of papaya leaves was lower but not significant (p> 0.05) compared to those who did not. The increase in the number of leukocytes cannot be restrained significantly by the administration of n-hexane extract. It was found that changes in leukocyte counts in acute inflammatory conditions with the administration of methanol extract and n-hexane extract of Papaya Leaves. The increase number of neutrophils and monocytes in acute inflammatory conditions can be significantly suppressed by the administration of methanol extract of papaya leaves. Key words: inflammation, carrageenan, papaya, Carica papaya l
Yield Analysis and Phytochemical Screening of Ethanol Extract of Phaleria macrocarpa Leaves Ira Cinta Lestari; Dharma Lindarto; Syafruddin Ilyas; Tri Widyawati; Suryani Eka Mustika
Buletin Farmatera Vol 8, No 1 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v8i1.11724

Abstract

Phaleria macrocarpa leaves have the potential to be used as raw materials for medicines derived from natural ingredients, but research is needed to determine the content and efficacy of these plants. This study aims to analyze the yield and screening of the content of phytochemical compounds in the ethanolic extract of the Phaleria macrocarpa leaves. This research is a descriptive study. Extract yield analysis was performed by calculating the weight ratio of the extract divided by the simplicia multiplied by one hundred percent. Screening for the phytochemical content was carried out for compounds belonging to the class of flavonoids, saponins, tannins, alkaloids, steroids, and triterpenoids. The results of the calculation of the yield of the extract obtained were 14.58% and the results of the phytochemical test showed that the extract contained flavonoids, alkaloids, tannins, glycosides, saponins, and steroids.
Co-Authors Ameta Primasari Anggraini, Dwi Rita Antika, Maya Anjelir ashfira Asmarinah Asmarinah Budianto Siregar Datten Bangun Dharma Lindarto Dian Handayani Ervina Sofyanti Evi Irianti fatchiyah . Fauzi Yusuf, Fauzi Halimatussakdiah Halimatussakdiah Harry Agusnar Harun Al Rasyid Hery Widijanto Indra Ira Cinta Lestari Kesuma Wardani Lestari, Chandra Marpaung, Okto P.E Masitta Tanjung Mesrawati Purba Mieke Hemiawati Satari Narmada , Ida Bagus Nukman Moeloek Nurjati C. Siregar Nursal Olivia Avriyanti Hanafiah Polem, Wardah Sawitri Ramlan Silaban Ria Lumbantoruan Rina Marintan Sitorus Rosidah, Rosidah Salomo Hutahaean Salomo Hutahaen Sari, Mutiara Indah Silvia W Lestari Sinaga, Ade Putra Fratama Siregar C Siregar, Siregar C Siti Bahirrah Suryani Eka Mustika Teguh Firdaus Ternala Alexander Barus Tisna Harmawan Tisna Hermawan Tri Widyawati Utmi Arma, Utmi Vivi Mardina Vivi Mardina Yasmeini Yazir