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All Journal Jurnal Kedokteran Brawijaya e-Journal Pustaka Kesehatan Jurnal Kesehatan STOMATOGNATIC- Jurnal Kedokteran Gigi Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) Journal of Dentomaxillofacial Science BIOEDUKASI JURNAL SKALA HUSADA: THE JOURNAL OF HEALTH Odonto dental journal
Happy Harmono
Department Of Dentistry-Biomedical Science, Oral Pathology And Maxillofacial Faculty Of Dentistry Universitas Jember Jember
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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EFFECTIVENESS OF ROBUSTA COFFEE BEAN EXTRACT GEL ON COLLAGEN FIBERS DENSITY IN POST-GINGIVECTOMY WOUND HEALING Ermawati, Tantin; Harmono, Happy; Kartikasari, Dania
Odonto : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (866.887 KB) | DOI: 10.30659/odj.8.1.45-53

Abstract

Background: Gingivectomy is a periodontal surgical procedure that eliminates excess gingival tissues by excision, usually to remove a gingival pocket which leads to scars and recontours the gingival to its proper anatomical form. Wound healing is a process to restore the missing functions and structures of a tissue due to injuries or inflammations. Robusta coffee bean contains many bioactive compounds that can accelerate the wound healing process. The study aimed to determinate the effectiveness of robusta coffee bean extract gel with concentration 40%,50%,60% on collagen fibers density in post-gingivectomy wound healing Method: 36 Wistar rats were divided into 9 groups: control, gingivectomy without therapy, gingivectomy +40% robusta coffee bean extract gel, gingivectomy +50% robusta coffee bean extract gel, and gingivectomy+60% robusta coffee bean extract gel. The last 4 groups were divided again into day 3 and 7 euthanasia. The results were processed by Trichrome Mallory to visualized the collagen fibers and then measured by ImageJ software.Result: Robusta coffee beans extract gel therapy with concentration 40%, 50% and 60% had higher average collagen fibers density compared to group without therapy.Conclusion: Robusta coffee bean extract gel increased the density of collagen fibers in post-gingivectomy wound healing
EFFECTIVENESS OF ROBUSTA COFFEE BEAN EXTRACT GEL ON COLLAGEN FIBERS DENSITY IN POST-GINGIVECTOMY WOUND HEALING Ermawati, Tantin; Harmono, Happy; Kartikasari, Dania
Odonto : Dental Journal Vol 8, No 1 (2021): July 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.8.1.45-53

Abstract

Background: Gingivectomy is a periodontal surgical procedure that eliminates excess gingival tissues by excision, usually to remove a gingival pocket which leads to scars and recontours the gingival to its proper anatomical form. Wound healing is a process to restore the missing functions and structures of a tissue due to injuries or inflammations. Robusta coffee bean contains many bioactive compounds that can accelerate the wound healing process. The study aimed to determinate the effectiveness of robusta coffee bean extract gel with concentration 40%,50%,60% on collagen fibers density in post-gingivectomy wound healing Method: 36 Wistar rats were divided into 9 groups: control, gingivectomy without therapy, gingivectomy +40% robusta coffee bean extract gel, gingivectomy +50% robusta coffee bean extract gel, and gingivectomy+60% robusta coffee bean extract gel. The last 4 groups were divided again into day 3 and 7 euthanasia. The results were processed by Trichrome Mallory to visualized the collagen fibers and then measured by ImageJ software.Result: Robusta coffee beans extract gel therapy with concentration 40%, 50% and 60% had higher average collagen fibers density compared to group without therapy.Conclusion: Robusta coffee bean extract gel increased the density of collagen fibers in post-gingivectomy wound healing
Efek Ekstrak Daun Sirih Merah (Piper crocatum) terhadap Perubahan Jumlah Osteoklas Area Tekanan Pergerakan Ortodonti pada Gigi Tikus Sari Setyaningsih; Latifa Eksa Salsabila; Happy Harmono; Herniyati
Jurnal Skala Husada : The Journal of Health Vol 23 No 1 (2026): Jurnal Skala Husada (JSH): The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Gaya mekanis ortodonti menghasilkan area tekanan dan tarikan sebagai proses remodeling tulang alveolar untuk keberhasilan dalam perawatan ortodonti. Area tekanan tersebut untuk menyiapkan ruang sebagai arah pergerakan gigi dan ruang tersebut akan terbentuk sebagai akibat aktifitas osteoklas. Penelitian ini bertujuan untuk mengetahui efek ekstrak daun sirih merah (Piper crocatum) terhadap perubahan jumlah osteoklas pada area tekanan pergerakan gigi ortodonti tikus. Desain penelitian adalah eksperimental laboratoris dengan rancangan post-test only control group design. Sampel berupa 36 ekor tikus Wistar jantan yang dibagi menjadi 9 kelompok: kontrol negatif (tanpa gaya, tanpa ekstrak), kontrol positif (diberi gaya mekanis), dan perlakuan (diberi gaya mekanis + ekstrak sirih merah 20 mg/kgBB) dengan waktu pengamatan 1, 3, dan 7 hari. Gaya mekanis diberikan pada gigi molar 1 rahang atas menggunakan Nickel-Titanium Closed Coil Spring dengan gaya sebesar 2,116 oz. Hasil penelitian menunjukkan jumlah osteoklas rata-rata tertinggi terdapat pada kelompok perlakuan 1 hari (36,25), 3 hari (33,5), dan 7 hari (34,75) yang meningkat secara signifikan dibandingkan kelompok kontrol. Aktivitas antioksidan ekstrak sangat kuat dengan nilai IC50 sebesar 40,2977 µg/ml. Berdasarkan pengamatan terjadi perubahan peningkatan jumlah osteoklas pada area tekanan dibandingkan kelompok kontrol, terutama pada pengamatan hari ke-7, yang berpotensi mempercepat pergerakan gigi ortodonti. Kata kunci: daun sirih merah, gaya mekanis ortodonti, osteoklas, area tekanan, remodeling tulang.
Co-Authors Ainunnusak Ayuningtyas Anisa Nur Hakima Arina, Yuliana Mahdiyah Daat Cicik Khilar Rizqi Desi Sandra Sari Didin Erma Indahyani Dina Nuur Rosyiidah Dwi Prijatmoko Erna Sulistyani Fany, Manta Fawwazi, Rafif Hanif Hakima, Anisa Nur Herniyati Herniyati Herniyati Herniyati Hestieyonini Hadnyanawati I Dewa Ayu Ratna Dewanti I Dewa Ayu Susilawati IDA Susilawati Iin Eliana Triwahyuni Kartikasari, Dania Latifa Eksa Salsabila Leliana Sabdra deviade Putri Leliana Sandra Devi Ade Putri Lisa Miftakhul Janna Maria Devitha Masari, Al Mayangsari, Zahra Melok Aris Wahyukundari Melok Aris Wahyukundari, Melok Aris Morauli, Fatricia Muchamad Ziyad Afif Nahdiya Fitriyana Nailah Rahmadani Nailufar, Khanun Perwitasuci, Brigitta Damai Prameswari, Syefira Putri Prasetya, Rendra C. Prihatiningrum, Berlian Pudjiastuti, Peni Pujiana Endah Qurratul Aini Wahyu Pratiwi Raditya Nugroho Riclas Yusuf Punta Wibisono Saikha Adila Azzah Sari Setyaningsih Setyaningsih, Sari Sholehah, Almaratus Sri Hernawati Suhartini Suhartini Tantin Ermawati Utha, Maria Fransisca Wanodyo, Ari Tri Wulandari, Widya Nurfitriastuti Yuliana Mahdiyah Daat Arina Zahara Meilawaty Zahara Meilawaty Zahreni Hamzah