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All Journal Majalah Kedokteran Bandung Althea Medical Journal Global Medical and Health Communication The Indonesian Biomedical Journal Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) JTP - Jurnal Teknologi Pendidikan Jurnal Integrasi Kesehatan dan Sains Jurnal Kebidanan Khatulistiwa JOURNAL LA MEDIHEALTICO Jurnal Kesehatan Metro Sai Wawai Media Penelitian dan Pengembangan Kesehatan
Setyorini Irianti
Department Of Obstetric And Gynecology, Faculty Of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : JOURNAL LA MEDIHEALTICO

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Folate Metabolism and Its Implications in Pregnancy Puspitasari, Maya Khaerunnisa; Irianti, Setyorini; Pramatirta, Akhmad Yogi; Wirawan, Wahyudi; Islamy, Nurul; Maelissa, Merlin Margreth; Lumentut, Anastasia Mariane
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1885

Abstract

The impact of folate nutritional status on a variety of pregnancy outcomes has been acknowledged for a considerable period of time. Folate is increasingly recognized not just as a nutrient required to prevent megaloblastic anemia during pregnancy, but also as a vitamin necessary for reproductive health. Folate plays an important role in several metabolic processes including DNA synthesis and methylation. Changes in folate status can affect the stability and integrity of DNA or affect the methylation patterns of some tissues. Folate is required for cell division and cell maintenance, as it acts as a co-enzyme in the transfer and processing of carbon units and plays an important role in the synthesis of nucleotides (thymidine) that are essential for de novo construction or DNA repair. The purpose of this article is to examine the function of folic acid in human health especially in pregnancy and to evaluate the benefits, concerns, and epigenetic effects of maternal FA in light of recent discoveries that are crucial for the development of future research.
Co-Authors Adhi Pribadi Ahmad Parwis Ahmad Parwis Akhmad Yogi Pramatirta, Akhmad Yogi Alfonsus Zeus Amillia Siddiq Ana Mariana, Ana Andi Kurniadi, Andi Andri Reza Rahmadi Anita D Anwar Anita Deborah Anwar Anwar, Anita D Aprianti, Nurul Azmi Arshandi Faisal Shiddiq Avivi, Safiya Fathina Aziz, Muhammad Alamsyah Benny Hasan Purwara Billy Nusa Anggara Budi Handono Budi Setiabudiawan Dany Hilmanto Dida Akhmad Gurnida Dodi Suardi Dyah Ayu Puspita Eddy Fadlyana Eduward Yacub Prasangka Fadhilah Zulfa Fahdiansyah Fahdiansyah Fahdiansyah Fahdiansyah Fauzi, Ali Amali Fidkya Allish Gusasih, Bahar Sangkur Herman Susanto Johanes C. Mose Johannes Cornelius Mose Jusuf Sulaeman Effendi Krisnadi, Sofie Kurnia Wahyudi, Kurnia Kusteja, Nadya Fauzia Laniyati Hamijoyo, Laniyati Lillah, Alfarisi Syukron Lulu Eva Rakhmilla, Lulu Eva Lumentut, Anastasia Mariane M. Rizkar Arev Sukarsa Maelissa, Merlin Margreth Nugrahani, Annisa Dewi Nurul Islamy Octaviana, Hana Rifa Passamula, Muhammad Hasan Puspitasari, Maya Khaerunnisa Raden Tina Dewi Judistiani Ramdhan, Muhammad Raihan Ruswana Anwar Sapiie, Tuti Wahmurti A. Sefty Mariany Samosir Sofia, Norlaila Sofie R. Krisnadi Sulaiman, Aina Zakia Supriyatin, Dedeh Susiarno, Hadi Syahidah, Putri Nadya Sylvia Rachmayati Tan, Zaki Miftah Nalalindra Teuku Kyan Nuryasin Truly Deti Rose Sitorus Truly Deti Rose Sitorus Vebri Anita Sinaga Will Hans Windi Nurdiawan Wirawan, Wahyudi Wiryawan Permadi Wulan Ardhana Iswari Yuni Susanti Pratiwi, Yuni Susanti Yuniartis, Putri Yunita Suryani Yunita Suryani Zulvayanti Zulvayanti