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High Neutrophils to Lymphocytes Ratio in Maternal Blood Serum as Risk Factor for Preterm Premature Rupture of Membrane Nicholas Renata Lazarosony; I Wayan Artana Putra; Ryan Saktika Mulyana; I Made Darmayasa; Ida Bagus Gde Fajar Manuaba; I Gde Sastra Winata; I Nyoman Gede Budiana
International Journal of Social Service and Research Vol. 3 No. 9 (2023): International Journal of Social Service and Research (IJSSR)
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v3i9.518

Abstract

Introduction: Neutrophil-to-lymphocyte ratio (NLR) has been extensively studied as a prognostic factor for various diseases based on systemic inflammation. Premature rupture of membranes (PROM) is an obstetric problem that does not only occur in term pregnancies but can also occur in preterm pregnancies. One of the main etiologies for premature rupture of membranes is inflammation. Knowing the difference in the NLR between preterm prematurerupture of membranes (PPROM) and without PPROM is important to increase understanding of the crucial role of NLR in predicting the incidence of PPROM. Method: This analytic case-control study compared NLR values ??in maternal blood serum between PPROM and without PPROM. This research was conducted in the emergencydelivery room and obstetrics and gynecology outpatient clinic at Prof. dr. I.G.N.G. Ngoerah Hospital Denpasar from February to June 2022. Results: A high NLR in maternal blood serum may be a risk factor for PPROM. Patients with a high NLR had a 4.5 times greater likelihood of experiencing PPROM than those with a low NLR (OR = 4.5; 95% CI = 1.4 – 13.83; p = 0.007). Conclusion: A high NLR in maternal blood serum is a marker of inflammation with an increased risk of 4.5 times for the occurrence of PPROM.
TINGKAT PENGETAHUAN REMAJA MENGENAI KANKER SERVIKS DI DUA SEKOLAH DI KABUPATEN GIANYAR, BALI I Komang Darma Wijaya; I Nyoman Gede Budiana; Ida Bagus Gede Fajar Manuaba; Endang Sri Widiyanti
Essence of Scientific Medical Journal Vol 21 No 2 (2024): Volume 21 No. 2 (Juli - Desember 2023) Essential: Essence of Scientific Medical
Publisher : Kelompok Ilmiah Hippocrates Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/essential.v21i2.109356

Abstract

ABSTRACT Cervical cancer become the second highest cancer case in Indonesia which attacks women with a mortality rate of up to 50%. The prevalence of this case has increased in recent years. This cancer, which is caused by infection with the HPV virus, can infect women from the age of 20 until the women is not in their reproductive age. The aim of this study was to determine the level of knowledge of adolescents regarding cervical cancer in two schools in Gianyar Regency. This research is descriptive study with a stratified random sampling method. The data collection method used was by giving questionnaires to students attending SMP Negeri 1 Gianyar and SMA Negeri 1 Gianyar. The questionnaire used consists of 2 aspects, namely knowledge of cervical cancer and knowledge of how to prevent cervical cancer. From this research, 209 respondents were obtained from the two schools, there are 30.14% had a good level of knowledge, 60.29% had a fairly good level of knowledge, and 9.57% had a poor level of knowledge.
Strategies for Managing Chronic Diseases Based on the Perspective of Bioethics and Human Rights Within the Framework of Health Law of The Republic of Indonesia Number 17 on year 2023 Ni Putu Purnianti; Ida Bagus Gede Fajar Manuaba
Journal of Law, Politic and Humanities Vol. 5 No. 4 (2025): (JLPH) Journal of Law, Politic and Humanities
Publisher : Dinasti Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jlph.v5i4.1526

Abstract

The increasing prevalence of chronic diseases in Indonesia requires serious attention to management strategies. This study aims to analyze chronic disease management strategies within the framework Health Law of the Republic of Indonesia Number 17 on year 2023 incorporating bioethical perspectives and human rights (HR). The approach ensures that health policies address not only technical and administrative aspects but also respect ethical values and justice. Using a qualitative method with a policy analysis approach, the research involves literature review, regulation analysis, and in-depth interviews with health and legal experts. The findings highlight bioethical principles, such as patient autonomy, equitable access to healthcare, and non-maleficence, which are key in supporting fair and inclusive policies. Furthermore, the right to health as part of HR emphasizes the importance of providing equitable services, particularly for vulnerable groups like chronic disease patients. The study concludes that the implementation of Health Law of the Republic of Indonesia Number 17 on year 2023 should consistently adhere to bioethics and HR principles to create a holistic, just healthcare system.