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All Journal BALI MEDICAL JOURNAL (BMJ) Buletin Udayana Mengabdi E-Jurnal Medika Udayana The Indonesian Biomedical Journal JBN (Jurnal Bedah Nasional) ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico Jurnal Ilmu Bedah Indonesia Indonesian Archives of Biomedical Research (InABR) Cermin Dunia Kedokteran Jurnal Neuroanestesi Indonesia Physical Therapy Journal of Indonesia Cermin Dunia Kedokteran
Sri Maliawan
Department Of Neurosurgery, Faculty Of Medicine Udayana University/Sanglah General Hospital, Bali-Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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TUBERCULOUS MASTITIS Ni Wayan Ariani Vitriasari; Putu Anda Tusta Adiputra; Sri Maliawan
E-Jurnal Medika Udayana vol 2 no2 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Tuberculous mastitis is a condition marked pathologyly with involvement extensively mamma lobules with epitheloid granuloma with various degree of caseation, what consist of Langhan's cells giant, cells of epiteloid, mononuclear cell infiltrate, with surrounding fibrosis, and with micro forming of abscess, which because of infection of Mycobacterium tuberculosis. Tuberculous mastitis happened more often at developing countries than developed countries, and especially happened at reproductive woman. The risk factors of this disease are lactation, multiparity, trauma, history of previous suppurative mastitis, and acquired immune deficiency syndrome (AIDS). Diagnose of tuberculous mastitis can be confirm by anamnesis, physical examination, and also some additional diagnostic test such as mammography, ultrasonography, computerized tomography scan (CT scan), scintimammography, magnetic resonance imaging (MRI), 3D magnetic resonance mammography, Gd-DTPA enhanced dynamic MRI, cytology, histopatology, culture, polymerase chain reaction (PCR), X-Ray, dan Mantoux skin test. Anti-tuberculous therapy forms the mainstay of treatment and conservative surgery is restricted to selected cases.
KARAKTERISTIK HISTOLOGIS, STADIUM KLINIS, DAN TERAPI KANKER KOLON PADA PASIEN LANJUT USIA DI RSUP SANGLAH Komang Ayu Vitriana Gamayanti; Sri Maliawan; Ketut Siki Kawiyana
E-Jurnal Medika Udayana vol 3 no 11(2014):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Kanker kolon merupakan jenis kanker yang umum dijumpai pada populasi geriatrik. Namun, penelitian mengenai karakteristik histopatologi, stadium klinis, dan terapi kanker kolon pada populasi geriatrik masih sangat terbatas. Penelitian ini bertujuan mendeskripsikan karakteristik histologi, stadium klinis, dan terapi kanker kolon pada kelompok pasien geriatri di RSUP Sanglah selama periode 2009-2013. Penelitian ini merupakan penelitian epidemiologi deskriptif yang menggunakan data register kanker kolon RSUP Sanglah selama periode tahun 2009-2013. Data mengenai jenis kelamin, tingkat pendidikan, tipe histologi, stadium, dan jenis terapi yang diperoleh dianalisis berdasarkan kelompok usia (<60 tahun vs. ?60 tahun). Sebanyak 97 pasien terdiagnosis kanker kolon berdasarkan hasil pemeriksaan histopatologi selama periode tahun 2009-2013, 68 (70,1%) diantaranya berusia di bawah 60 tahun sedangkan 29 (29,9%) pasien berusia 60 tahun ke atas. Adenokarsinoma merupakan tipe histologi yang paling umum dijumpai pada kedua kelompok usia. Proporsi kasus adenokarsinoma lebih tinggi pada kelompok pasien geriatrik (96,5% vs. 82,4%). Kelompok usia muda memiliki proporsi kasus mucinous adenocarcinoma, signet-ring cell carcinoma, small cell carcinoma, dan malignant GIST (gastrointestinal stromal tumor) yang lebih tinggi. Kelompok pasien geriatrik memiliki proporsi kasus dengan stadium dini yang lebih rendah (stadium in situ, I, dan II: 41,4% vs. 51,5%) dan proporsi kasus dengan stadium lanjut yang lebih tinggi (stadium IV: 20,7% vs. 13,2%). Proporsi kasus yang menerima pembedahan kuratif lebih rendah pada kelompok pasien geriatrik (75,9% vs. 80,9%). Dapat dimpulkan bahwa pasien geriatrik dengan kanker kolon cenderung memiliki stadium tumor yang lebih lanjut dan dengan demikian, kurang representatif untuk menerima terapi pembedahan kuratif. Faktor-faktor yang berkontribusi terhadap fenomena ini harus ditelaah lebih jauh pada penelitian selanjutnya.
LUMBAR SPINAL CANAL STENOSIS, DIAGNOSTIC AND MANAGEMENT Putu Indah Budi Apsari; I Ketut Suyasa; Sri Maliawan; Siki Kawiyana
E-Jurnal Medika Udayana vol 2 no 9 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Lumbar spinal canal stenosis is a narrowing of the osteoligamentous vertebral canal and/or the intervertebral foramina causing compression of the thecal sac and/or the caudal nerve roots. The prevalence are five per 1000 person over 50 years old in USA. Male more than female, the most affect L4 -L5 and L3-L4. Low back pain is the most symptom. Routine diagnostic examination can be done plain x-ray lumbosacral, CT scan, and MRI. Management therapy can divide to two conservative and operative therapy. Complication of operative therapy is infection, vacular injury, cardiorespiratory disturbance due to embolization and death. The prognosis related with severity of symptom, degree of stenosis, surgical procedure and comorbid conditions.
BREAST CORE NEEDLE BIOPSY Reni Widyastuti; Putu Anda Tusta Adiputra; Sri Maliawan
E-Jurnal Medika Udayana vol 2 no2 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Nowadays, there are many kinds of biopsy. One that can be done in breast is core needle biopsy. Core needle biopsy is a tissue sampling procedure using hollow core needle size 11-16 gauge. The operator can direct the needle directly into the palpable lesion or by using imaging. This is a safe, effective, time efficient, and less costly. The disadvantage among others, can lead to infection, scarring at the biopsy area, and spread of malignant cells in the needle route.
SKIN CANCER Made Putri Hendaria; AAGN Asmarajaya; Sri Maliawan
E-Jurnal Medika Udayana vol 2 no2 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Skin is an organ which protect the human body from the environment. It was build by milion cells. According to the changes in human lifestyle which tends to unhealthy life, increasing ultraviolet radiation, toxins, and genetics makes the cells who build the skin do the abnormal growth being cancer cells. Classification of skin cancer is according the most common three types, they are Basal Cell Carcinoma, Squamous Cell Carcinoma, and Malignant Melanoma. More than 3,5 milion skin cancer cases was happened in United States, which makes it become the most common cancer type in that country. Skin cancer diagnosis is build from anamnesis, physic examination about skin eufloressence, using dermoscopy, and histopatologic examination as the gold standar. Therapy for skin cancer is classified to surgery and non surgery therapy and its prognostic is depend to the types of the skin cancer itself.
DIAGNOSIS AND TREATMENT OF URETHRAL STRICTURE A.A. Ngr. Agung Wistara Widya; A.A. Gde Oka; Ketut Siki Kawiyana; Sri Maliawan
E-Jurnal Medika Udayana vol 2 no3 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Retention of urine is the lower urinary tract obstruction caused by the inability of squirting urine, so that the urine collected in the bladder exceeds the maximum limit. One reason is due to narrowing of the lumen of the urethra, called urethral stricture. The diagnosis of urethral stricture can we enforce by way of history, physical examination, and investigation. Curative treatment of this disease is surgery, but not as rare as some surgical techniques can lead to high disease recurrence for patients.. Thus the proper and adequate treatment is necessary to avoid the risk of recurrence of urethral stricture disease.
MANAGEMENT OF INTERNAL HEMORRHOID WITH RUBBER BAND LIGATION PROCEDURE I Made Arya Winangun; Putu Anda Tusta Adiputra; Sri Maliawan; Ketut Siki Kawiyana
E-Jurnal Medika Udayana vol 2 no 10 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Hemorrhoid is regarded as the cases most seen in population. The prevalence of this cases about 4,4% with the incidence 12 of 1.000 patient. The current management of hemorrhoid is lifestyle modification, conservative management such as farmacology, minimally invasive treatment and more aggressive therapy using surgical procedure. Rubber band ligation was one of the minimally invasive procedures. This procedure was easy, inexpensive, and can be done outpatient using simple tools without complicated procedure like hemorrhoidectomy. Some studies explained rubber band ligation effectively done in internal hemorrhoid grade II and grade III even this procedure still had minimal complication such as bleeding and unpleasentness
Comparison of Mortality and Glasgow Outcome Scale Extended (GOSE) between Craniotomy and Decompressive Craniectomy in Patients with Traumatic Acute Subdural Hematoma at Sanglah General Hospital, Bali Ni Luh Putu Julita Yanti; I Wayan Niryana; Sri Maliawan; I Nyoman Semadi; Tjokorda G. B. Mahadewa; I G. A. B. Krisna Wibawa
JBN (Jurnal Bedah Nasional) Vol 6 No 1 (2022): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2022.v06.i01.p03

Abstract

Background: Craniotomy and decompressive craniectomy and are surgical modalities for the evacuation of acute subdural hematoma (SDH). These two techniques show different outcomes in various existing studies. The superiority between either techniques remains controversial. Objective: To determine the outcome comparison of mortality and Glasgow Outcome Scale Extended (GOSE) craniotomy with decompressive craniectomy in patients with traumatic acute SDH. Methods: This is a historical cohort study. Samples of the study were collected from January 2018 to March 2020 at Sanglah General Hospital. All patients with acute traumatic SDH who underwent SDH evacuation with craniotomy and decompressive craniectomy were assessed for mortality status at discharge and GOSE 3 months after surgery. Independent T-test will be carried out if the numerical variable were all normally distributed, while Mann-Whitney U test will be performed if otherwise. A Chi-square test will be performed on all unpaired categorical variables. Statistical analysis was performed with SPSS 25 with 95% confidence intervals. Results: As many as 40 subjects with traumatic acute SDH who underwent craniotomy and 40 subjects with traumatic acute SDH who underwent decompressive craniectomy were included in this study. There was no significant difference in mortality (RR: 1; 95% CI 0.67-1.87; p=0.651) and GOSE score (p=0.718) in traumatic acute SDH who underwent craniotomy or decompressive craniectomy. Conclusion: There was no difference in mortality and GOSE outcomes between a craniotomy and decompressive craniectomy for management of traumatic acute SDH.
Dekompresi Mikrovaskular pada Neuralgia Trigeminalis dan Spasme Hemifasialis Sri Maliawan; Tjokorda G.B. Mahadewa; Nyoman Golden; Wayan Niryana
Jurnal llmu Bedah Indonesia Vol. 35 No. 2 (2007): Desember 2007
Publisher : Ikatan Ahli Bedah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46800/jibiikabi.v35i2.129

Abstract

Pendahuluan : Menurut konsesus spesialis bedah saraf pada The 5th International Meeting of The Society for Microvascular Decompression Surgery, 2002, di Matsumoto, Jepang, terapi terpilih untuk neuralgia trigeminalis dan spasme hemifasialis adalah melakukan operasi dekompresi mikrovaskular (DMV). Tujuan penulisan ini untuk mengetahui hasil operasi DMV pada penderita dengan neuralgia trigeminalis (NT) dan spasme hemifasialis (SHF) di RS Sanglah (RSS), Denpasar. Metode : Studi kohort tanpa kelompok kontrol dilakukan terhadap data rekam medis penderita NT dan SHF di RS Sanglah (RSS), Denpasar, yang menjalani DMV selama periode tahun 1991-2006. Prosedur DMV terdiri atas tindakan memperbaiki posisi pembuluh darah yang menekan dan membebaskan sumbu nervus trigeminus dengan meletakkan teflon di antara nervus dan pembuluh darah. Subjek dievaluasi dalam kurun waktu antara 1 sampai 12 tahun pascoperasi. Data dianalisis untuk memperoleh angka kesembuhan segera, tingkat kepuasan pasien, angka kesembuhan tidak sempurna, angka kekambuhan, dan komplikasi operasi. Hasil : Dari 37 orang subjek terdapat 30 orang dengan NT dan 7 orang dengan SHF. Kesembuhan segera setelah operasi 93,3% pada NT dan 85,7% pada SHF. Subjek merasa puas dengan tindakan yang dilakukan sebanyak 83,3% pada NT dan 71,4% pada SHF. Kesembuhan tidak total 10% pada NT dan 14% pada SHF. Gangguan pendengaran pascaoperasi 13,3% pada NT dan 14% pada SHF. Diskusi : Teknik reposisi pembuluh darah yang menekan nervus trigeminus atau nervus fasialis sebagai prosedur DMV dapat memberikan hasil yang memuaskan untuk mengobati NT dan SHF.
Purple Sweet Potato Reduces Malondialdehyde and TNF-a, Increases p53, and Protects Histopathological Appearance in Formaldehyde-induced Nasopharyngeal Carcinoma Rats Ni Ketut Susilawati; I Wayan Putu Sutirta Yasa; Wayan Suardana; Sri Maliawan; I Made Jawi; Achmad Chusnu Romdhoni; Hamsu Kadriyan; I Wayan Gede Artawan Eka Putra; I Gusti Kamasan Nyoman Arijana
The Indonesian Biomedical Journal Vol 14, No 2 (2022)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v14i2.1906

Abstract

BACKGROUND:Purple sweet potato tuber ethanol extract (PSPTEE) has been known to have benefits in various disease, including to prevent nasopharyngeal carcinoma (NPC). However, there has been no research on PSPTEE in preventing the proliferation of nasopharyngeal mucosal epithelial cells induced by formaldehyde through the oxidative stress mechanisms and inflammatory process. Studies have proven the effect of PSP on various cancer cells, but the carcinogenesis process of the nasopharyngeal mucosal epithelium is still limited. Hence, this study aimed to demonstrate the mechanism for preventing histopathology changes with PSPTEE due to formaldehyde exposure.METHODS: Thirty-two formaldehyde-induced Wistar rats were treated with or without 1g/kgBW/day PSPTEE for 16 weeks. Malondialdehyde (MDA) level were examined with spectrophotometry method, while tumor necrosis factor (TNF)-α and p53 with enzyme linked immunosorbent assay (ELISA) method. The histopathology appearance of the nasopharyngeal epithelium was observed with hematoxylin-eosin (HE) staining.RESULTS: MDA and TNF-α levels in control and treatment group were 22.89±2.84 μM; 9.83±0.89 μM and 84.18±11.58 ng/L; 73.92±10.59 ng/L, respectively, and they showed significant difference. Meanwhile, the level of p53 showed no significant difference. Histopathology appearance showed a significant difference. Path analysis for MDA, TNF-α and p53 levels contributed 28.7% to histopathology appearance. MDA have an effect on significant direct effect on TNF-α. TNF-α has a significant direct effect to histopathological appearance. Indirect influence MDA on histopatological appearance were smaller than the direct effect. TNF-α has the greatest influence on histopatological appearance.CONCLUSION: Formaldehyde induces the histopathology appearance in nasopharyngeal epithelium. This study also demonstrates the mechanism to prevent the nasopharynx epithelial histopathology appearance by administration of PSPTEE.KEYWORDS: PSP, MDA, TNF-α, p53, nasopharynx epithelial
Co-Authors A.A. Gde Oka A.A. Ngr. Agung Wistara Widya AA GN Asmara Jaya AAGN Asmarajaya Agung Bagus S. Satyarsa Andi Asadul Islam Arasy, Mohd Firdaus Astawa N. M., Astawa N. Astawa P., Astawa B. Sinaga D.P.W. Wardhana Dewa Putu Wisnu Wardhana Dian Megasafitri Dwikinta, Made Anindya Eka J. Wahjoepramono Ekaputra Ekaputra, Ekaputra G. I. B Bomba Gatot S. Lowrence, Gatot S. Gde Rastu Adi Mahartha Gede Febby Pratama Kusuma Gede Wirya Kusuma Duarsa Gunawan, Made Favian Budi Hamsu Kadriyan I Dewa Made Sukrama I Gede Sutawan I Gusti Agung Bagus Krisna Wibawa I Gusti Ayu Agung Laksemi I Gusti Kamasan Arijana I Gusti Putu Hendra Sanjaya I Ketut Suyasa I Ketut Wiargitha I Made Arya Winangun I Made Bakta I Made Gotra I Made Jawi I Made Stepanus Biondi Pramantara I Nyoman Semadi I W. Sudarsa I Wayan Gede Artawan Eka Putra I Wayan Niryana I Wayan Putu Sutirta Yasa I. B. Tjakra Wibawa Manuaba Ida Bagus Adi Kayana Ilhamjaya Patellongi Iwan Antara Suryadi Johansyah, Theodorus Kevin Putra K.K. Putra Kadek Dede Frisky Wiyanjana Kadek Dede Frisky Wiyanjana Ketut Putu Yasa Ketut Siki Kawiyana Kevin Kristian Putra Koerniawan, Heru Sutanto Komang Ayu Vitriana Gamayanti L. K. Widnyani Wulan Laksmi L. R. M. Lengkong M Wiryana Made Agus Mahendra Inggas, Made Agus Mahendra Made Indra Erlangga Prathiwindya Made Putri Hendaria Mardliyah, Mumtazah Moses Kharisma Setyawan Ni Ketut Susilawati Ni Luh Putu Julita Yanti Ni Putu Enny Pratiwi Suardi Ni Wayan Ariani Vitriasari Niryana, , I Wayan Nyoman Golden Putu Anda Tusta Adiputra Putu Indah Budi Apsari Putu Pramana Suarjaya Putu Primeriana Nugiaswari Raka-Sudewi A. A. Reni Widyastuti Romdhoni, Achmad Chusnu S. Awyono Satoto D., Satoto Setiawan, I Gede Budhi Sista Satyarsa, Agung Bagus Sista Soetomo, Cindy Thiovany Stanley-Ketting Oliver Suryadi N. T., Suryadi N. Tiffany, Tiffany Tjokorda Gde Agung Senapathi Tjokorda Gde Bagus Mahadewa W. A., W. Wayan Suardana Willy Adhimarta Wiryana M., Wiryana Yutina Himawan